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Medical Forum / Diseases and Disorders / Hepatitis / May 2007

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SVR

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rhanson - 23 May 2007 09:56 GMT
Hi Everyone,

Last year I posted a couple questions here and recieved wonderful responses
from some of you. You guys helped me realize the importance of researching
the disease and that I should have taken a more active role in my treatment.
Thanks for that! I know I read something about the likelyhood of SVR and
testing undetectable at 12 or 24 weeks but can't seem to find that
information again. I have been all over the place trying to find the info. I
was hoping someone could point me in the right direction. My uncle recently
started the Tx and so have some others that I know. I would like to offer
them a few pointers so they don't make the same mistakes I did during the
treatment and to help make sure they have the best chance possible at beating
this. There is power in knowledge (and numbers) right?

Thanks!
greyhackles - 23 May 2007 15:11 GMT
>Hi Everyone,
>
[quoted text clipped - 11 lines]
>
>Thanks!

Short answer: For genotype 1s, a viral load drop of at least 2log (that'd be
99%) by week 12 is generally necessary to remain in the running for SVR, and
clearing by week 12 portends a very good shot at SVR.

Conversely, failure to reach a 2log drop at week 12, or not being clear by
week 24, are profoundly negative indicators for SVR for g1s. Not clearing by
24 weeks usually leads to treatment discontinuation if following the
conventional treatment regimen.

/greyhackles
 
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