Medical Forum / Diseases and Disorders / Hepatitis / May 2009
No Clearance Of Hep C
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ironjustice - 05 May 2009 14:33 GMT Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
ironjustice - 05 May 2009 16:24 GMT Spamming Fuckwit
ironjustice - 05 May 2009 16:40 GMT On May 5, 8:24 am, ironjustice <flakey...@aol.com> wrote: snip <<
Shteater you and your buddies .. commonly .. are carrying this sht ..
Don't be cutting this and make sure to tell your buddy about this article and how you are NOT cured like you've been telling everybody for years ..
You shteating .. lying .. freak ..
Again .. this one is VERY important to protect the general population from you Hepatitis ridden shteaters ..
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Ken - 05 May 2009 17:17 GMT Spamming Fuckwit
ironjustice - 05 May 2009 17:49 GMT On May 5, 9:17 am, Ken <flakey...@earthlink.net> wrote: snip <<
Shteater you and your buddies ALL are carrying this sht .. around ..
Don't be cutting this article and make sure to tell your buddy about this .. article
You are NOT cured ..
You shteating .. freak ..
Sooo once again .. this one is VERY important to protect the general population from you disease Hepatitis ridden mutated shteaters ..
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
ironjustice - 05 May 2009 20:23 GMT Rusty the Retard..Spamming Fuckwit
ironjustice - 05 May 2009 22:43 GMT On May 5, 12:23 pm, ironjustice <flakey...@earthlink.net> wrote:snip <<
Shteater ..
All of you shteaters were TOLD to stay off my posts ..
All of you shteaters were TOLD .. no posting to my threads ..
All of you shteaters .. MUST .. remember .. when you cut my posts .. it is evidence OF .. the dysfunctional predatorial nature of you .. disease ridden mutated shteating .. **freaks** ..
Don't be cutting this article shteater ..
You shteating disease ridden mutated freaks are NOT .. welcome ..
This article is VERY important .. shteater ..
It is to protect the general population from you disease hepatitis ridden mutated shteaters ..
Don't cut this article .. shteater ..
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
ironjustice - 05 May 2009 23:39 GMT Spamming Fuckwit
ironjustice - 06 May 2009 03:14 GMT On May 5, 3:39 pm, ironjustice <flakey...@aol.com> wrote: snip <<
You shteaters seem to have a hard time understanding ..
You shteaters are abnormal ..
You shteaters are disease ridden mutant .. freaks ..
Shteaters are not allowed on my threads ..
You shteaters were .. all .. TOLD .. no congregating ..
Shteaters .. remember .. when you cut my posts .. it is evidence OF .. the dysfunctional predatorial nature of you .. disease ridden mutated .. shteating .. **freaks** ..
You disease ridden mutated shteaters must remember that dysfunctional nature of yours is VERY common to men who prefer .. to have sex with boys ..
http://www.traditionalvalues.org/homosexual_movement_and_pedophilia/
http://www.talk2action.org/story/2006/10/3/21245/3789
http://predatorsafety.blogspot.com/2008/11/homosexual-grooming-of-chi...
Predator Safety Dedicated To The Protection Of Our Children
All these posts .. evidence .. mental instability .. common to homosexuals .. IE: "Dysfunctional Homosexuals"
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Dwight - 06 May 2009 03:21 GMT > On May 5, 3:39 pm, ironjustice <flakey...@aol.com> wrote: snip << > [quoted text clipped - 108 lines] > DEAD PEOPLE WALKING > http://tinyurl.com/zk9fk tom, please quit crossposting.
Thank you,
Dwight
Chuck - 06 May 2009 21:41 GMT Who is this moron and why is he allowed to walk amongst the human populous of earth? I guess the pig farms in Mexico wouldn't have him.... or maybe they did.
ironjustice - 07 May 2009 00:38 GMT On May 6, 1:41 pm, "Chuck" <ch...@canada.ca> wrote:: snip <<
You act like the shteaters ..
They too seem to have a hard time understanding ..
YOU specifically were TOLD to stay off my threads ..
DOOOO .. it ..
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
Cactus Jammies - 07 May 2009 04:27 GMT Don't let him get you worked up, Chuck. I trimmed the address line in this reply to this group only. He likes to spam five at once and gets his jollies from the negative feedback, which rationalizes him using his foul and derogatory language. Leave him be, put him in your killfile so that his messages don't get to your computer. It should be under tools, put in trash immediately or something like that. You don't need to be baited. It only increases your suffering and not his to get worked up about it and reply to his stuff.
cool is best, the liver has to clean up your bloodstream that fills with fight or flight adrenaline and cortisol. It cannot be burned off as you suffer through treatment, and beyond it, for that matter.
cactus jammies
> Who is this moron and why is he allowed to walk amongst the human populous > of earth? I guess the pig farms in Mexico wouldn't have him.... or maybe > they did. Waterspider - 07 May 2009 19:22 GMT > Don't let him get you worked up, Chuck. I trimmed the address line in > this reply to this group only. He likes to spam five at once and gets his [quoted text clipped - 14 lines] >> populous of earth? I guess the pig farms in Mexico wouldn't have him.... >> or maybe they did. Sadly, ole Ironsides is mentally ill and cannot be prevented from making a fool of himself on unmoderated newsgroups. CJ's advice is the best-- put him in your killfile.
ironjustice - 10 May 2009 08:46 GMT On May 7, 11:22 am, "Waterspider" <nos...@all.com> wrote: snip <<
You think you are special .. ?
You didn't say a word about .. iron .. liver .. or fat ..
Now unless I misunderstand how the groups work .. that precludes you from posting to my threads ..
Either stay on topic .. iron in the liver .. elevated iron in the liver .. fat in the liver .. or fkff ..
Understand .. you "Still Contagious" dckhd .. ?
DOOOO .. it .. you "Still Contagious" dckhd ..
And stay FARRR away from ME ..
-----------------
Patients With Resolved Hepatitis C Likely Still Contagious ScienceDaily (May 4, 2009) —
Patients with chronic hepatitis C that has been resolved through therapy or immune response may still be able to infect others with the virus.
About 170 million people worldwide are infected with hepatitis C virus, which can progress to chronic hepatitis, cirrhosis and even liver cancer. In some individuals, the infection seems to resolve, either spontaneously from the efforts of the immune system, or after treatment with interferon and ribavirin.
Patients who achieve a sustained viral response show no clinical or biochemical evidence of liver disease and standard tests can no longer detect the virus in their blood. However, more sensitive research tests are finding that such patients often still have miniscule amounts of the virus in their bodies. No one knows if these trace remainders are infectious.
Researchers led by Tomasz I. Michalak of Memorial University of Newfoundland, Canada examined this question using a system that allows for propagation of HCV in human T cells in vitro.
They began with nine patients with HCV who had achieved a sustained viral response that persisted for at least two years after treatment. HCV RNA was detectable in their blood only with the more sensitive tests.
The researchers set up twelve cultures of lymphoid cells from healthy donors, and exposed them to plasma or to supernatants of cultured circulating lymphoid cells from the HCV patients. Eleven of the cell cultures became HCV RNA positive. Furthermore, HCV from three of the nine patients was able to establish active HCV replication in the cultures.
“These findings provide in vitro evidence that trace quantities of HCV persisting in the circulation for a long time after therapeutically induced resolution of CHC can remain infectious,” the authors report.
Interestingly, HCV replication in the T cells was prevented after neutralization of the virus, and by treatment with interferon.
This study is the first to investigate the infectivity of HCV traces that remain when the infection is occult. It agrees with previous animal studies of the same question.
“Our present findings reveal that HCV circulating in some individuals with resolved hepatitis C is capable of inducing productive infection in vitro at doses of 20 to 50 copies,” the authors conclude. “This can be interpreted as a strong indication of potential virus infectivity in vivo.”
--------------------------------------------------------------------------------
Journal reference:
MacParland, Sonya A.; Pham, Tram N.Q.; Guy, Clifford S.; Michalak, Tomasz I. Hepatitis C Virus Persisting at Low Levels after Clinically Apparent Sustained Virological Reponse to Antiviral Therapy Retains Its Infectivity in Vitro. Hepatology, May 2009 Adapted from materials provided by Wiley-Blackwell.
Who loves ya. Tom
Jesus Was A Vegetarian! http://tinyurl.com/2r2nkh
Man Is A Herbivore! http://tinyurl.com/a3cc3
DEAD PEOPLE WALKING http://tinyurl.com/zk9fk
"Cactus Jammies" <cactusjamm...@retinalcircus.orb> wrote in message
> news:RysMl.27097$PH1.24396@edtnps82... > [quoted text clipped - 22 lines] > > - Show quoted text -
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