On May 4, 11:31 am, ironjustice <flakey...@earthlink.net> wrote: snip
<<

You shteaters .. are everywhere .. aren't ya .. shteater ..

On our phones .. in our parks .. in our schools .. on the internet ..

Displaying .. predation ..

They are going to jail or hang you in Scotland .. shteater ..

Which do YOU .. prefer .. shteater .. personally ..

Would you prefer .. death by misadventure .. spontaneous
combustion .. or .. suicide ..

This is for those less informed among us .. that wouldn't be
a smart guy like you who eats .. sht .. so you don't have to worry ..

It IS for most shteaters .. though ..

For the less informed amongst us ..

Phytic acid and catechin are both found in plants ..

So a tomato sandwich .. or something ..

"Phytic acid with catechin in the treatment and prevention of hepatic
cirrhosis"

Possible Synergestic Role of Phytic Acid and Catechin
in Ameliorating the Deteriorative Biochemical Effects
Induced by Carbon Tetrachloride in Rats
Journal of Applied Sciences Research, 3(11): 1449-1459,
Corresponding Author: Sohair Aly Aly Hassan,
Medicinal Chemistry Department, National Research Centre.
E-mail: sohaireslam...@hotmail.com, Tel: 02241015611449
The Sohair Aly Hassan, Maha Zaki Rizk, Fathia El-Sharkawi,
Osama Badary and Mai Osman Kadry 11231
Medicinal Chemistry Department, National Research Centre.
1Biochemistry Department, Faculty of Pharmacy, Helwan University.
2Clinical Pharmacy Department, Faculty of Pharmacy, Ain shams
University.

Abstract:
Carbon tetrachloride (CCl )-induced hepatotoxicity in rats
was used to assess the effect ofcatechin, phytic acid and
their combination on the indexes of in rats cirrhosis.
Liver profileenzymes,oxidative status and histological
examinations revealed that catechin and phytic acid
significantly4arrested progression of hepatic cirrhosis
induced by CCl .
Reduced activities of serum alanineaminotransferase
(ALT), aspartate aminotransferase (AST), alkaline
phosphatase (ALP), lactatedehydrogenase (LDH) and
cholesterol level, were detected while the levels of total
protein and albuminwere increased.
Electrophoretic separation of LDH isoenzymes revealed
a marked reduction in LDH 4 &54isoenzymes by combined
treatment with both phytic acid and catechin.
The development of CCl -inducedhepatic cirrhosis altered
the redox state resulting in decreased hepatic glutathione
(GSH), increased serumnitric oxide (NO) levels and the
formation of liver lipid peroxidative products which were
partially normalized by treatment with catechin and its
combination with phytic acid, respectively.
Moreover, P53 was increased significantly with catechin
while a marked reduction in sialic acid level was noted post
phytic acid treatment.
Histological examinations showed that the combination of
both phytic acid andcatechin nearly returned collagen fiber
distribution to normal pattern.
These results demonstrate that administration of phytic acid
together with catechin may be useful in the treatment and
prevention of hepatic cirrhosis on the experimental level.

4. Key words: Cirrhosis, Catechin, Phytic acid, Synergism, P53, CCl
2007© 2007, INSInet Publication

Who loves ya.
Tom

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