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Medical Forum / Diseases and Disorders / Hepatitis / October 2008

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MOM! DAD! IM HOME!

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maha - 23 Oct 2008 00:55 GMT
About two years ago, I wandered in here and lurked for awhile as I was
starting treatment for my Hep C.  Never participated much, but I did
like reading posts from people who were going through the same thing I
was.  I failed to get an SVR.  In fact, the virus had returned in week
24 but due to problems with the lab, I didin't even find out until a
year after my treatment had ended.  As you can understand, I was
crestfallen and a bit angry that I had been subjected to an additional
5 months of unnecessary side effects.

There is a new study that is specifically for Genotype 1 patients that
did not respond to the conventional therpay.  It's the same drill with
the peg-intron and ribavirin, excepth they have added an experimental
drug called boceprevir (a protease inhibitor) which has it's own set
of delightful side effects..  From what I understand, the initial
results have been very promising.  

I start again Friday.  I have this unreal since of dread about the 48
weeks of feeling ill, but I still think it's the right thing to do.

Graham
greyhackles - 23 Oct 2008 03:48 GMT
>About two years ago, I wandered in here and lurked for awhile as I was
>starting treatment for my Hep C.  Never participated much, but I did
[quoted text clipped - 16 lines]
>
>Graham

Yup, Boceprevir is Schering-Plough's candidate alternative to Vertex's
Telaprevir. Both are protease inhibitors, and both are showing solid
enhancement of SVR rates when combined with the conventional therapy drugs.
Telaprevir has been in Phase 3 studies, while Boceprevir is in Stage 2, but
coming on strong from all the reports.

Cheers - and here's hoping you are in the study arm that gets the Boceprevir!

/greyhackles
Paul - 23 Oct 2008 21:19 GMT
On Wed, 22 Oct 2008 18:55:43 -0500, maha <rgf3@RemovEbellsouth.net>,

>About two years ago, I wandered in here and lurked for awhile as I was
>starting treatment for my Hep C.  Never participated much, but I did
[quoted text clipped - 14 lines]
>I start again Friday.  I have this unreal since of dread about the 48
>weeks of feeling ill, but I still think it's the right thing to do.

Welcome back.  I'm glad I only needed one stab at tx and I feel for
you.  I'm disgusted that you were subjected to so much unnecessary tx
as well.  Not the worst horror story I've heard but certainly a
candidate for the top 20%.
Best of luck with it this time around.
 
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