Medical Forum / Diseases and Disorders / Hepatitis / October 2008
For the newbies
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Suds - 05 Jul 2008 20:05 GMT It's like a band of malicious vagabonds is wandering around inside your body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry from the assembled hooligans. "But first," says their leader, how about a little nausea?" A louder cheer goes up, and they start off to do their mischief, but a small voice pipes up and says, “headache, let’s do a headache”. A murmur runs through the pack, and the leader says, headache goes without saying. It’s de rigor.” “Balance.” Cries yet another virus. Let’s make him stagger like a drunk.” “They begin chanting, “Balance, balance, balance, until the leader raises his hand and quiets the crowd. If we have time, we’ll do balance, but headache diarrhea and nausea is plenty for one day. We’ll start with balance first thing in the morning. But let’s get started.” They tramp off chanting headache diarrhea nausea, headache diarrhea nausea in cadence with their footfalls.
Suds
Thip - 05 Jul 2008 22:58 GMT > It's like a band of malicious vagabonds is wandering around inside your > body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry [quoted text clipped - 15 lines] > > Suds I ain't no newbie, but I sure needed a good laugh! Thanks, Suds.
Waterspider - 05 Jul 2008 23:42 GMT > It's like a band of malicious vagabonds is wandering around inside your > body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry [quoted text clipped - 15 lines] > > Suds Hahahahah, oh my, that sure does bring back some fond memories ;-)
Great stuff, thanks for posting.
Dwight - 06 Jul 2008 00:08 GMT >> It's like a band of malicious vagabonds is wandering around inside your >> body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry [quoted text clipped - 19 lines] > > Great stuff, thanks for posting. I agree with the others, great post. I think I can remember those meetings taking place just before waking each morning.
Dwight
topcat - 06 Jul 2008 01:50 GMT > It's like a band of malicious vagabonds is wandering around inside your > body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry from [quoted text clipped - 11 lines] > > Suds And then a small voice in the back yells, "what about ITCHIES", don't forget the ITCHIES hang in there Suds. TC
greyhackles - 06 Jul 2008 04:40 GMT >It's like a band of malicious vagabonds is wandering around inside your >body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry from [quoted text clipped - 11 lines] > >Suds Ah, yes - Act One. For some reason it's a lot funnier reading it than I remember living it.
I can't wait to read about Acts Two and Three ;-)
/greyhackles
dBo - 06 Jul 2008 23:01 GMT ROFL yes far funnier remembering than walking thru it -
let's see I think
Act 2 invovled stuff like mixing up envelopes and mailing credit card payments to myself (lets hear it for Late Fees!) (No Brain Fog problems, HERE! )
Act 3 involved ripping the bottom of my radiator out on a brand new extra high curbing installed at my local hospital when I went for blood tests, yup yup yup great memories.
Hang in there Suds and keep the sense of Humor Intact, it will definitly help get you thru!
Thip - 07 Jul 2008 01:13 GMT > ROFL yes far funnier remembering than walking thru it - > [quoted text clipped - 10 lines] > Hang in there Suds and keep the sense of Humor Intact, it will > definitly help get you thru! Don't forget about the times you forgot to sign the check....or the time(s) you forgot to pay the bill entirely....or going to the bank to cash a check, then counting the money and insisting the clerk shorted you $200--til you found it in another wallet compartment (I wanted to crawl under a rock).
Ah, the good ole days. And when you fail to slay the dragon, the good ole days just keep coming back and back and back and back and.......
Dwight - 07 Jul 2008 01:24 GMT >> ROFL yes far funnier remembering than walking thru it - >> [quoted text clipped - 18 lines] > Ah, the good ole days. And when you fail to slay the dragon, the good ole > days just keep coming back and back and back and back and....... One of my favorites was trying to remember if I had taken my Riba yet. Someone here suggested pouring all the pills on the counter, divide by 4 and see where you were at that point. With a three month supply and not being able to think clearly enough to count, much less divide, I usually just gave up and took them again. Elmo was the one that gave me the easiest solution, put them in a pill container with the days of the week on the lids, duh. :) Some of the World's greatest revelations seem to be the easiest. Wish Elmo would stop by again for a visit.
Dwight
Thip - 07 Jul 2008 21:25 GMT >>> ROFL yes far funnier remembering than walking thru it - >>> [quoted text clipped - 30 lines] > > Dwight Yeah, me too. I miss the old goofball.
I've kept my pills in 7-day reminders for years now. I have my a.m. and p.m., and while I do forget to take them occasionally, at least the full cup reminds me that I forgot.
TX-012 - 08 Jul 2008 20:14 GMT > >>> ROFL yes far funnier remembering than walking thru it - > [quoted text clipped - 38 lines] > > - Show quoted text - My process involves a large pill container, my various bottles of pills, and two shelves. When I get up, and after I pee, etc. I trudge over to the shelves. All of the pill bottles will be on one shelf; today, the lower shelf. I grab the large empty pill bottle in which I store all my various pills and capsules for the day, and, one by one, put each daily supply of vitamin c, ribavirin, omega-3s, etc. in said bottle, after which I place the vitamin c, ribavirin, omega-3s, etc. on the other (today, upper) shelf.
And then during the course of the day I consume all my meds and vitamins and crap which I have placed in The Daily Pill Bottle. Voila!
amzolt - 10 Jul 2008 18:48 GMT And, Act Four:
"Hey, how much muscle ache does this guy get today?"
"Can't we screw up his vision more?!"
"OK, vision/muscles and a bonus today is making him forget who he really, actually IS!"
"Yeah!" "Right On!!" "Fuckin' A!!!"
~ Alex
metspitzer - 12 Jul 2008 01:55 GMT >>> ROFL yes far funnier remembering than walking thru it - >>> [quoted text clipped - 29 lines] > >Dwight Asking yourself........am I in the bathroom because I have taken my meds or because I need to take them?
chardonney9 - 09 Jul 2008 01:52 GMT > It's like a band of malicious vagabonds is wandering around inside your > body. "Gee, what shall we do today? "Diarrhea diarrhea!" Comes the cry from [quoted text clipped - 11 lines] > > Suds It's nice to hear the truth from those going through it rather than what the doctors tell you. They admit side effects but gloss over them and go onto something else as soon as possible.
Am I right to assume that most of you don't get treatment till you are pretty sick from the hep c? I know many places won't let you get it unless you are pretty far along.
My GP doctor runs a clinic for hep c and I went to a meeting where we were told what the treatment was and what would happen should be choose to go through with it. The good part is that I don't have to wait and I can start treatment soon as I want to. The bad news is I live alone and must work to support myself. I don't feel I can do this and go through the treatment at the same time.
At that time I was so tired all the time that I'd go out and work cleaning houses and businesses and come home exhausted, not even able to keep up with my own housework.
Since then, since I have time, I've tried a few natural alternatives for treatment and for energy and other symptoms. I wll be asking for a fresh viral load test tomorrow when I see the doc.
Chardonney
chardonney9 - 11 Jul 2008 02:19 GMT Is there a reason nobody has responded to my post? Did I do something wrong? I really need to talk to people who have been through this.
Char
> It's nice to hear the truth from those going through it rather than what > the doctors tell you. They admit side effects but gloss over them and go [quoted text clipped - 20 lines] > > Chardonney greyhackles - 11 Jul 2008 02:39 GMT >Is there a reason nobody has responded to my post? Did I do something >wrong? I really need to talk to people who have been through this. [quoted text clipped - 25 lines] >> >> Chardonney Heck, you didn't say anything "wrong", it just wasn't clear you were actually looking for feedback.
As to the question you posed, I suspect most folks start treatment because of test results, not significant symptoms. Sure, there are those whose disease has progressed to some degree of frankness, but most aren't there yet.
Otherwise....It's been said often here, but some folks get through treatment with minimum side effects - while others get pounded. Aside from any pre-existing head trips that may get significantly amplified, I don't think there's any way to predict which bin one will fall in.
And then there is the duration of treatment to consider. There is no doubt that folks on the 48 week course (or longer) will generally get whacked the hardest, verses the luckier ducks that can scoot by on the 24 week plan.
So, if you happen to be infected with genotypes 2 or 3, you'd be more likely to get it over and done before having to face the "rock pile" of that last 24 weeks that genotypes 1 and 4 have to pound. That's a major advantage in many ways, for sure.
How long have you been HCV+? Have you had a biopsy? If not, does your doctor plan on doing one?
Cheers
/greyhackles
chardonney9 - 11 Jul 2008 14:43 GMT >> Is there a reason nobody has responded to my post? Did I do something >> wrong? I really need to talk to people who have been through this. [quoted text clipped - 53 lines] > > /greyhackles I'm lucky enough to have type 2 which I understand is easier to kill. Far as I know I've been positive since the 1970's. I didn't know it till about a year ago or so. I had a blood transfusion during that time which may have been the cause.
I've not had a biopsy and she didn't mention one. Should I have one?
I have no symptoms except for being tired all the time and I've found alternative solutions for that. I'm just one of those people who usually get every symptom possible when taking meds. It took me decades to find something to actually treat my depression. I was on St John's Wort for years and it was helping a lot till last year something changed and it wouldn't work on this new depression. Best I found is it was related to a tumor on my parathyroid gland.
From what I've read, several factors would make me a bad candidate for the clinic. Depression, being fat, having other problems like diabetes.
I have reduced my viral load from almost 15 million down to less than 3 million, and maybe more. I've not been tested in a few months. I did most of it by using colloidal silver and now I'm trying a couple other methods that have worked for others. The silver and alpha lipoic acid have both helped with my energy levels quite a bit. Even if they did nothing to reduce the hepc I'd still take them just for the energy factor.
Char
Cactus Jammies - 11 Jul 2008 15:59 GMT > I'm lucky enough to have type 2 which I understand is easier to kill. Far > as I know I've been positive since the 1970's. I didn't know it till about [quoted text clipped - 22 lines] > > Char Chardonnay: Three million is twice what my VL was when I entered tx. Take tx. As you have stated, you have an excellent chance to kill the dragon, certainly moreso than many of us because of differences in genotypes. Take tx.
The other stuff is snake oil.
cactus jammies
chardonney9 - 11 Jul 2008 22:37 GMT >> I'm lucky enough to have type 2 which I understand is easier to kill. Far >> as I know I've been positive since the 1970's. I didn't know it till about [quoted text clipped - 32 lines] > > cactus jammies I will do it should what I'm doing fail.
Could you be more specific as to what you are calling snake oil? I know colloidal silver works for a lot of things and works well. Even hospitals use silver in a newborn's eyes, in salve for burns, in bandages, etc. What do you know about alternative treatments?
I've used it instead of antibiotics many times. It's gotten rid of many infections in and on me as well as my pets. I did find two other modalities to try in addition to the silver and I will find out shortly if they are working. I was supposed to have an appointment a few days ago but someone screwed up my appointment time and I could not see anyone.
Char
greyhackles - 12 Jul 2008 02:10 GMT >I will do it should what I'm doing fail. > [quoted text clipped - 10 lines] > >Char So, you advocate Colloidal Silver for *viral* infections. And you think antioxidants will cure chronic HCV - based on an unvetted testimonial covering 3 alleged patient histories written at least a decade or two ago by a "doctor" pushing his book. And you will wait until your condition worsens before seriously considering the standard of care - which, for your genotype - has a cure rate better than 3 out of 4.
My diagnosis: you're at least a couple of sandwiches short of a picnic.
But good luck anyway...
/greyhackles
chardonney9 - 12 Jul 2008 02:31 GMT >> I will do it should what I'm doing fail. >> [quoted text clipped - 12 lines] > > So, you advocate Colloidal Silver for *viral* infections. Yes I do and so do many others. Can you show me it doesn't work for viral infections?
And you think
> antioxidants will cure chronic HCV - based on an unvetted testimonial covering > 3 alleged patient histories written at least a decade or two ago by a "doctor" > pushing his book. It was a valid published study.
And you will wait until your condition worsens before
> seriously considering the standard of care - which, for your genotype - has a > cure rate better than 3 out of 4. I was never told I was seriously sick at this point. Did they forget to tell me something?
Char
> My diagnosis: you're at least a couple of sandwiches short of a picnic. > > But good luck anyway... > > /greyhackles Paul - 13 Jul 2008 08:35 GMT On Fri, 11 Jul 2008 21:31:28 -0400, chardonney9 <chardonney9@notearthlink.net>, in message ID <3_-dnTGYyejzlOXVnZ2dnUVZ_qbinZ2d@earthlink.com>, in the newsgroup alt.support.hepatitis-c wrote:
>> So, you advocate Colloidal Silver for *viral* infections. > >Yes I do and so do many others. Can you show me it doesn't work for >viral infections? It's also true that most people who have got rid of hep-c have drunk milk at some time in their lives.
Waterspider - 13 Jul 2008 18:36 GMT > On Fri, 11 Jul 2008 21:31:28 -0400, chardonney9 > <chardonney9@notearthlink.net>, in message ID [quoted text clipped - 8 lines] > It's also true that most people who have got rid of hep-c have drunk > milk at some time in their lives. And all heroin addicts drank milk, so obviously drinking milk leads to hard drugs and heroin addiction ;-)
Paul - 15 Jul 2008 00:50 GMT On Sun, 13 Jul 2008 10:36:37 -0700, "Waterspider" <nospam@all.com>, in message ID <hJidnbl6EMutoOfVnZ2dnUVZ_vKdnZ2d@posted.deltacablecommunications>, in the newsgroup alt.support.hepatitis-c wrote:
>And all heroin addicts drank milk, so obviously drinking milk leads to hard >drugs and heroin addiction ;-) Damn !! No wonder I got in such a mess :-)
Waterspider - 15 Jul 2008 01:13 GMT > On Sun, 13 Jul 2008 10:36:37 -0700, "Waterspider" <nospam@all.com>, in > message ID [quoted text clipped - 6 lines] > > Damn !! No wonder I got in such a mess :-) Bet you wore diapers, too. Very sad, you never had a chance ;-)
Paul - 15 Jul 2008 23:54 GMT On Mon, 14 Jul 2008 17:13:48 -0700, "Waterspider" <nospam@all.com>, in message ID <1Oednf1Wru2-c-bVnZ2dnUVZ_gadnZ2d@posted.deltacablecommunications>, in the newsgroup alt.support.hepatitis-c wrote:
>> On Sun, 13 Jul 2008 10:36:37 -0700, "Waterspider" <nospam@all.com>, in >> message ID [quoted text clipped - 8 lines] > >Bet you wore diapers, too. Very sad, you never had a chance ;-) And I was a middle child too. No hope for me eh? :-)
TX-012 - 12 Jul 2008 20:10 GMT > My diagnosis: you're at least a couple of sandwiches short of a picnic. > > But good luck anyway... > > /greyhackles Hmmm. Needless to say, there are many people out there who are neither as bright nor as rational about treatment options as yourself. Regardless of whether or not Chardonney falls into this category , a shitload of people with hep c certainly DO. Look at the article below. Don't know what the demographics of the CA prison system are, but I imagine the average hepper-in-prison is probably less intelligent than the average inmate, who is in turn less intelligent than the average American; you are probably looking at an average IQ under 90 for this population...Minimally educated, too...
Reaching and treating these people is gonna be...challenging, to say the least, notwithstanding the fact that many are black and do much less well on interferon to begin with...
I'm not sure writing these people off is the best option...even if, only cynically, it makes poor economic sense, given the cost of treatment later on down the line.
Needless to say, though, patience and persistence are assets in dealing with such a population. And of course communications must be catered to the target audience...
Suit alleges inadequate care of hepatitis C outbreak in California prisons An attorney in the federal class-action lawsuit says up to 40% of the 171,000 inmates in state prisons may be infected by hepatitis C.
By Patrick McGreevy
Los Angeles Times Staff Writer
July 9, 2008
SACRAMENTO — California prison officials are failing to adequately treat an outbreak of hepatitis C that has infected thousands of inmates, a federal class-action lawsuit alleged Tuesday.
The lawsuit was filed in Los Angeles on behalf of inmates including Kevin Jackson, who is at the California State Prison at Solano and alleges that he has not received proper treatment since being diagnosed with the disease in August 2007.
Up to 40% of the 171,000 inmates in state prisons may be infected with hepatitis C, said Shawn Khorrami, an attorney for Jackson.
The lawsuit alleges that the California Department of Corrections and Rehabilitation is wrongly excluding thousands of inmates from liver biopsies and antiviral treatments and allowing their diseases to progress to more advanced stages of liver damage. Khorrami said the lack of proper diagnostic testing and treatment further spreads the disease among inmates.
"The Department of Corrections is playing judge, jury and executioner and doling out a punishment that no court would allow," Khorrami said. "This is unacceptable, inhumane and constitutes cruel and unusual punishment."
The lawsuit against Robin Dezember, director of the Division of Correctional Health Care Services for the prison system, is the latest in a string of legal challenges alleging that officials have failed to provide adequate medical care to inmates.
In response to previous litigation alleging substandard treatment of chronic diseases, the federal court appointed J. Clark Kelso as a receiver authorized to take control of and overhaul healthcare in the prison system. Kelso has been pressuring the state to spend billions of additional dollars to upgrade medical treatment for inmates, including the addition of 10,000 hospital beds in the prison system.
As a result, the receiver believes that the lawsuit is redundant, spokesman Luis Patino said.
"This lawsuit is seriously flawed," he said. "I can't imagine how many times the same class is going to sue the same agency for the same reason."
Kelso is aware of the problem with treating hepatitis C and "it is already being fixed," Patino said.
However, Khorrami said the receiver has not made enough progress in addressing the epidemic, which has the potential to affect the general public as infected prisoners are released into their communities.
Waterspider - 12 Jul 2008 20:24 GMT <snip> the average inmate, who is in turn less intelligent than the average American; you are probably looking at an average IQ under 90 for this population...Minimally educated, too...
Whoa right there. The average IQ in a federal penal institution is *higher* than on the street. Formal education is irrelevant here too; IQ tests are designed to measure intelligence, not education. Intelligence is an ability to learn, not how much one has been taught.
TX-012 - 12 Jul 2008 21:07 GMT > <snip> > the average inmate, who is in turn less intelligent than the average [quoted text clipped - 5 lines] > designed to measure intelligence, not education. Intelligence is an ability > to learn, not how much one has been taught. When you are done building your straw man, perhaps a straw hat might be useful, it being summer.
1) The average inmate in US prisons is certainly less intelligent than the average American.
2) The CA Prison system is not a federal prison system.
For fun sadistics on this sorta stuff, check out
http://www.lagriffedulion.f2s.com/
http://www.vdare.com/
Waterspider - 13 Jul 2008 00:53 GMT On Jul 12, 12:24 pm, "Waterspider" <nos...@all.com> wrote:
> "TX-012" <withba...@aol.com> wrote > [quoted text clipped - 9 lines] > ability > to learn, not how much one has been taught. When you are done building your straw man, perhaps a straw hat might be useful, it being summer. 1) The average inmate in US prisons is certainly less intelligent than the average American. 2) The CA Prison system is not a federal prison system. For fun sadistics on this sorta stuff, check out http://www.lagriffedulion.f2s.com/ http://www.vdare.com/
Yeah, your straw hat links were fun :-) Perhaps the average US prison inmate is less intelligent than the average US free citizen, but not so in Canada. When I worked in corrections in the early 1980s, a study proving this was released internally. I'm sorry to say that I can't find a damn thing about it from googling though, so I'll drop it.
greyhackles - 12 Jul 2008 21:22 GMT >> My diagnosis: you're at least a couple of sandwiches short of a picnic. >> [quoted text clipped - 4 lines] >Hmmm. Needless to say, there are many people out there who are neither >as bright nor as rational about treatment options as yourself. [...]
Not sure what your point - if there was one - actually is, but I posted a link to that story five days ago, and there's virtually no relevance to this thread to be found therein.
This isn't about someone with arguably no treatment options, this is about someone already symptomatic, tx-naive, with the easiest-to-treat genotype, consciously deciding to avoid the one regimen that could have significantly positive effects.
I don't think one has to be particularly bright, rational - or well educated on the subject - to find that hard to support...
/greyhackles
TX-012 - 12 Jul 2008 21:43 GMT this is about
> someone already symptomatic, tx-naive, with the easiest-to-treat genotype, > consciously deciding to avoid the one regimen that could have significantly > positive effects. > > I don't think one has to be particularly bright, rational - or well educated > on the subject - to find that hard to support... Obviously, I don't support that ("consciously deciding to avoid the one regimen that could have significantly positive effects") . But I also would urge patience with such people--greater patience than I think you've shown thus far...They may come around at some point. Whether or not you wish to try is up to you...
The story of Anne Sullivan Macy & Helen Keller comes to mind...
chardonney9 - 12 Jul 2008 22:30 GMT >>> My diagnosis: you're at least a couple of sandwiches short of a picnic. Actually I tend to be years ahead of others in thinking.
>>> But good luck anyway... >>> [quoted text clipped - 11 lines] > consciously deciding to avoid the one regimen that could have significantly > positive effects. Show me that it's the one regimen that could cure me. I've heard it stated more than once that alternative medicine doesn't work but nobody has given me anything to back that up. I want to know specifically which ones you know won't work and why. I want to know specifically if you have information about the ones I'm using.
Show me that colloidal silver won't work, show me alpha lipoic acid won't work, show me oleander won't work. All of you have been glossing over all that. If you really believe they won't work then show me why it won't work.
Simple enough thing to want to know.
Char
> I don't think one has to be particularly bright, rational - or well educated > on the subject - to find that hard to support... > > /greyhackles Sara - 11 Jul 2008 17:50 GMT (snipped)
> I'm lucky enough to have type 2 which I understand is easier to kill. Far > as I know I've been positive since the 1970's. I didn't know it till about [quoted text clipped - 22 lines] > > Char Please quit playing games with your health and get to a doc and get on treatment. you have a great chance to clear the virus, and you'd only have to be on the meds for 24 weeks. Most of us don't start getting really dragged out from the meds til about that point in tx anyway -- and the things you are putting into your body are surely causing more harm than good. Do some research, talk to a doctor... just check the archives for this group even! I'd recommend a good hep-c clinic at a teaching hospital, but find someone who knows what they are talking about, get a biopsy done to see what kind of shape your liver is in, and get on the meds. And, for what it's worth, viral load means squat -- the counts vary all the time but if you have a viral count of thousands as opposed to millions, you've still got the virus and you still need the drugs that can destroy it.
Sara
TX-012 - 11 Jul 2008 21:32 GMT > (snipped) > [quoted text clipped - 39 lines] > > Sara Amen. The sooner you start, the better your chances of clearing. If you ARE already symptomatic, you need to do this ASAP. In the meantime, lose some weight. This will improve your chances of an SVR.
And if your doctor does not have a problem with it, try to get on 20-80 mgs Lescol per day while you are on tx, unless you are already on another statin. Google Lescol or fluvastatin and hepatitis c for more info.
chardonney9 - 11 Jul 2008 22:43 GMT > Amen. The sooner you start, the better your chances of clearing. If > you ARE already symptomatic, you need to do this ASAP. I'm not except for being tired but that's been going on for years.
In the
> meantime, lose some weight. This will improve your chances of an SVR. Been trying for many years and it just doesn't happen. I don't drink sodas, eat very few carbs, not into sweets. I think it's thyroid related but they insist it's not.
> And if your doctor does not have a problem with it, try to get on > 20-80 mgs Lescol per day while you are on tx, unless you are already > on another statin. Google Lescol or fluvastatin and hepatitis c for > more info. I won't take statins. Horrible side effects! I did read that they work well for this and did try to take them once but now I know a lot more about them. Talk about snake oil!
Char
TX-012 - 12 Jul 2008 01:25 GMT > > Amen. The sooner you start, the better your chances of clearing. If > > you ARE already symptomatic, you need to do this ASAP. > > I'm not except for being tired but that's been going on for years.<< Being excessively fatigued is a classic hep c symptom. The fact that it's been going on for years is not good.
> In the > [quoted text clipped - 12 lines] > well for this and did try to take them once but now I know a lot more > about them. Talk about snake oil! Statins, while ineffective by themselves, do apparently help combo treatment for hep c work better for many people. They do indeed have side effects for some, but in the context of Pegasys, ribavirin and possibly NEUPOGEN, any side effects you experience from 20 mgs of Lescol per day are likely to be trivial---if that.
chardonney9 - 14 Oct 2008 14:42 GMT >>> And if your doctor does not have a problem with it, try to get on >>> 20-80 mgs Lescol per day while you are on tx, unless you are already [quoted text clipped - 9 lines] > possibly NEUPOGEN, any side effects you experience from 20 mgs of > Lescol per day are likely to be trivial---if that. Cholesterol-lowering drugs and the effect on muscle repair and regeneration
http://www.eurekalert.org/pub_releases/2008-09/aps-cda092308.php
HILTON HEAD, SC—Statins are powerful drugs that reduce "bad" cholesterol and thus cut the risk of a heart attack. While these medications offer tremendous benefits to millions, they can carry side effects for some. The most frequently reported consequence is fatigue, and about nine percent of patients report statin-related pain. Both can be exacerbated when statin doses are increased, or physical activity is added. The results of a new study may offer another note of caution for high-dose statin patients. Working with primary human satellite cell cultures, researchers have found that statins at higher doses may affect the ability of the skeletal muscles–which allow the body to move–to repair and regenerate themselves.
The study is entitled "Simvastatin Reduces Human Primary Satellite Cell Proliferation in Culture." It was conducted by Anna Thalacker-Mercer, Melissa Baker, Chris Calderon and Marcas Bamman, University of Alabama at Birmingham. They will discuss their findings at the American Physiological Society (APS; www.The-APS.org) conference, The Integrative Biology of Exercise V. The meeting is being held September 24-27, 2008 in Hilton Head, SC.
The Study
Statins have been reported to have adverse effects on skeletal muscle in both human and animal models causing cramping and fatigue and potentially myopathy. Relatively little is known regarding the effect of statins on the muscle progenitor cells (i.e., satellite cells (SC)) which play a key role in skeletal muscle repair and regeneration following exercise or injury. SC remain in a quiescent state until stimulated to proliferate. Statins are known to have antiproliferative effects in other cell types and therefore may inhibit or effect this critical step in muscle repair. Thus it is important to understand the influence of statins on SC function which may further affect the overall health and physiology of human skeletal muscle..
The study examined the proliferative capacity of human satellite cells in culture, which were exposed, to a lipophilic statin: simvastatin. The aim of the study was to determine SC viability during proliferation when treated with statins which may be indicative of the ability of SCs to undergo mitosis (i.e. divide to make new cells).
The research team used primary cell lines isolated from quadriceps muscle biopsies. SC were mixed and grown for 48 hours with several concentrations of statin: 0.0, 0 plus the solvent DMSO (control), 0.05, 0.1, 1.0, 10, or 100µM. The MTS assay was utilized to measure cell viability/reproducibility.
Additionally the investigators determined the effects of varying concentrations of simvastatin on SCs in different states (i.e., undergoing differentiation or differentiated into myotubes).
Key Findings
The researchers found the following:
* There was a dose dependent decrease in the viability of the satellite cells at 1.0, 10 and 100µM concentrations of simvastatin. At approximately 5.0 µM concentration the viability of the proliferating cells was reduced by 50% (equivalent to the availability of simvastatin in circulation from a 40 milligram dose per day used in some patients). Specifically, the higher end concentrations led to reduced SC proliferation, which would likely negatively affect the muscle's ability to heal and/or repair itself.
* There was no change in the viability of satellite cells at concentrations of 0.05 or 0.1µM.
* Cell viability was reduced by approximately half in differentiating cells and myotubes with concentrations of 1.0 and 5.0 µM, respectively.
Next Steps
According to Dr. Thalacker-Mercer, a member of the research team, "While these are preliminary data and more research is necessary, the results indicate serious adverse effects of statins that may alter the ability of skeletal muscle to repair and regenerate due to the anti-proliferative effects of statins."
Looking ahead, she added, "We are very interested in these effects in the older population. It is possible that older adults may not be able to distinguish between muscle pain related to a statin effect or an effect of aging and therefore adverse effects of statins in older adults may be under-reported. Therefore, our next step is to examine statins among older adults."
lorettaann - 12 Jul 2008 23:39 GMT > > Amen. The sooner you start, the better your chances of clearing. If > > you ARE already symptomatic, you need to do this ASAP. [quoted text clipped - 19 lines] > > Char Crap. I just posted an introductory post, and it went - I think - to the wrong place. I should have posted here, but it went in under the thread heading "Interesting article." I am new here and haven't figured out how all this works yet. So, it's there, if anyone, you know, is interested. ;)
chardonney9 - 11 Jul 2008 22:28 GMT > (snipped) >> [quoted text clipped - 28 lines] > Please quit playing games with your health and get to a doc and get on > treatment. I don't believe in games. I would not have tried what I did without seeing proof it could work. There is not a great deal of scientific proof naturally, the drug companies can't control these methods and have no interest in paying money out to studies they can't make money on.
you have a great chance to clear the virus, and you'd only
> have to be on the meds for 24 weeks. Most of us don't start getting > really dragged out from the meds til about that point in tx anyway -- That's good to know should I end up going that route. And I will should my other methods fail. I do need to give them a try though.
> and the things you are putting into your body are surely causing more > harm than good. Do some research, I did do research which is why I am doing what I am doing. I'm extremely prone to depression and till a few months ago couldn't find an alopathic med that actually worked. I'm on generic Zoloft now and it's ok but I don't think it would keep me together under extreme stress. I've tried most the other ones out there with disastrous results.
Did you research the methods I'm using? How can you say they will "surely" cause more harm than good? Do you really think that only doctors have solutions? I was hoping that someone here had genuinely looked into alternative meds, even if just to lessen the symptoms. Have you?
I've found two different things that give me back my energy so I can get up and do things. My doctor tells me there is nothing she can do to give me energy and then next visit asks me if I'm exercising. As if I had enough energy to get off the bed after work and ride a bike or something!
talk to a doctor... just check the
> archives for this group even! I'd recommend a good hep-c clinic at a > teaching hospital, That is what I have available but they scare me quite honestly. I've been in pain, most likely from a tumor on my parathyroid gland for over ten months now and can't get them to remove it because my test results don't fit their criteria. Nevermind my bones were hurting from my body pulling calcium from them. They only care about the numbers.
but find someone who knows what they are talking
> about, I think I have done that.
get a biopsy done to see what kind of shape your liver is in,
See what I mean? Nobody has mentioned a biopsy over the past few years. And they do tests they don't tell you about, they don't give you results. I've been waiting for about a month now to find out what my neck MRI actually showed. Only a doctor can tell me but I can't get in front of one to ask.
and
> get on the meds. I'm on meds. They just aren't the same as yours.
And, for what it's worth, viral load means squat -- the
> counts vary all the time but if you have a viral count of thousands as > opposed to millions, you've still got the virus and you still need the > drugs that can destroy it. Then what should I be looking at if not my viral load?
Char
> Sara metspitzer - 12 Jul 2008 01:27 GMT > get a biopsy done to see what kind of shape your liver is in, > [quoted text clipped - 3 lines] >neck MRI actually showed. Only a doctor can tell me but I can't get in >front of one to ask. No news usually means good news. Had something abnormal showed up in your MRI (and maybe your labs), you would have probably received a phone call.
I don't know much about alternative methods, but I am putting my money on modern medicine.
It took me two times to clear, but I have been clear for over 3 years now. I took "the pen" (still not sure what they call that---Intron A?) for 10 months and then straight to Pegasus for a year.
chardonney9 - 12 Jul 2008 02:34 GMT >> get a biopsy done to see what kind of shape your liver is in, >> [quoted text clipped - 7 lines] > your MRI (and maybe your labs), you would have probably received a > phone call. I did get a phone call, from a nurse passing on a vague message from the ENT doc. When I asked for specifics she said only a doctor could do that but that she could not get a doctor to call me. I had to make an appointment with my GP just for that.
> I don't know much about alternative methods, but I am putting my money > on modern medicine. > > It took me two times to clear, but I have been clear for over 3 years > now. I took "the pen" (still not sure what they call that---Intron > A?) for 10 months and then straight to Pegasus for a year. How many of those 22 months were problems for you? Char
metspitzer - 12 Jul 2008 03:22 GMT >>> get a biopsy done to see what kind of shape your liver is in, >>> [quoted text clipped - 22 lines] >How many of those 22 months were problems for you? >Char None of them were fun, but all of them were worth it.
Treatment sucks, but liver failure sux worse.
Sara - 12 Jul 2008 03:48 GMT (snipped)
> And, for what it's worth, viral load means squat -- the >> counts vary all the time but if you have a viral count of thousands as >> opposed to millions, you've still got the virus and you still need the >> drugs that can destroy it. > > Then what should I be looking at if not my viral load? The results of your liver biopsy :)
> Char >> >> Sara Paul - 13 Jul 2008 08:55 GMT On Fri, 11 Jul 2008 17:28:41 -0400, chardonney9 <chardonney9@notearthlink.net>, in message ID <9tadna1s_d4XTerVnZ2dnUVZ_qfinZ2d@earthlink.com>, in the newsgroup alt.support.hepatitis-c wrote:
>Then what should I be looking at if not my viral load? Liver condition (determined by biopsy) is more important than viral load. I had mid range damage to my liver yet my viral load was a mere 91,000. LFTs were all normal (or very close) too. Relying on viral load to make your choices is like trying to understand a film from one snapshot of it. I'm not having a go at you honestly but I checked out a number of things to try and avoid interferon as well. As you say, it's hard to totally disprove many of the "alternative" remedies as it's not financially viable for drug companies to do the tests. However, although some alternatives may give a feel good factor that may (or may not) boost the immune system which may (or may not) in turn reduce viral load, such things can turn out to be fool's gold. Now it may well be that an elderly hep-c patient would be better off not treating if they were non-symptomatic as they would likely die from old age before suffering with their liver. Also there are other very good reasons for not treating because the side effects for some are worse than living with the disease and, in rare cases, can kill. Some other illnesses can exclude the possibility of tx. But you know all this already. So why am I bothering? Oh yeah. I lost two good friends to hep and it's not a pretty way to die. As far as I know, interferon (latterly taken along with ribavirin) are the only things that shift the virus and keep it shifted. Yes I suffered while taking the stuff. Not as badly as some. It did work though - and I had the relatively easy geno 2 which was a big help.
chardonney9 - 11 Jul 2008 22:47 GMT > get a biopsy done to see what kind of shape your liver is in How do they biopsy a liver?
Char
TX-012 - 12 Jul 2008 02:25 GMT > > get a biopsy done to see what kind of shape your liver is in > > How do they biopsy a liver? > > Char http://digestive.niddk.nih.gov/ddiseases/pubs/liverbiopsy/
You may or may not need one. I had an ultrasound, but no biopsy.
chardonney9 - 12 Jul 2008 03:11 GMT >>> get a biopsy done to see what kind of shape your liver is in >> How do they biopsy a liver? [quoted text clipped - 4 lines] > > You may or may not need one. I had an ultrasound, but no biopsy. I have had two ultrasounds and discovered I have gall stones. So if the ultrasound looks good I don't need a biopsy?
Sounds good to me! Char
Waterspider - 12 Jul 2008 20:33 GMT >>>> get a biopsy done to see what kind of shape your liver is in >>> How do they biopsy a liver? [quoted text clipped - 8 lines] > ultrasound looks good I don't need a biopsy? > Sounds good to me! Yep, sounds good (just like coloidal silver), but it's not. Ultrasound will show gallstones (in the gallbladder or ducts) and other masses that shouldn't be in the area. It will *not* show cellular damage, which is what's destroying your liver, cell by cell, three billion times a day. Btw, gallstones are common in those with hepatitis c (that's how my hep c was finally diagnosed).
Paul - 13 Jul 2008 08:57 GMT On Fri, 11 Jul 2008 22:11:49 -0400, chardonney9 <chardonney9@notearthlink.net>, in message ID <2aednTjDs_x5j-XVnZ2dnUVZ_trinZ2d@earthlink.com>, in the newsgroup alt.support.hepatitis-c wrote:
>I have had two ultrasounds and discovered I have gall stones. So if the >ultrasound looks good I don't need a biopsy? > >Sounds good to me! My ultrasound was fine. My biopsy revealed mid range damage (roughly translated as stage 2 grade 3).
greyhackles - 13 Jul 2008 16:41 GMT >On Fri, 11 Jul 2008 22:11:49 -0400, chardonney9 ><chardonney9@notearthlink.net>, in message ID [quoted text clipped - 8 lines] >My ultrasound was fine. My biopsy revealed mid range damage (roughly >translated as stage 2 grade 3). Same here - indeed, the ultrasound tech kept telling me how great my liver looked - no masses, no enlargement, clean smooth edges, and on and on.
Then I got my biopsy report: stage 2 going on 3, grade 3 inflammation. Whoa! That got me off the fence in a hurry...
Cheers
/greyhackles
Waterspider - 12 Jul 2008 20:28 GMT On Jul 11, 2:47 pm, chardonney9 <chardonn...@notearthlink.net> wrote:
> Sara wrote: > > get a biopsy done to see what kind of shape your liver is in > > How do they biopsy a liver? > > Char http://digestive.niddk.nih.gov/ddiseases/pubs/liverbiopsy/
You may or may not need one. I had an ultrasound, but no biopsy.
TX, you should know this by now, but an ultrasound does not show damage to the liver cells (although it will show an enlarged liver or a suspicious mass). Please don't tell people they may not need a biopsy when they need to know the extent of their liver damage. Please.
TX-012 - 12 Jul 2008 21:04 GMT > On Jul 11, 2:47 pm, chardonney9 <chardonn...@notearthlink.net> wrote: > [quoted text clipped - 13 lines] > mass). Please don't tell people they may not need a biopsy when they need to > know the extent of their liver damage. Please. I never wrote that, of course. An ultrsound (best = Fibroscan) does not, naturally, allow microscopic examination of *actual liver cells*. What it does provide is useful info as to the condition of the liver as a whole. I don't believe anyone disputes the fact that, biopsies, though imperfect (they are not always representative of the liver as a whole) are _better_ than the best ultrasounds as a diagnostic tool for prospective hep c patients. But ultrasounds/scans are often used in place of biopsies these days for certain groups, for certain reasons. Interesting links:
http://tinyurl.com/64uzea
http://www.echosens.com/Expertise/FibroScan.html
http://en.wikipedia.org/wiki/Ultrasound
http://www.natap.org/2005/HCV/093005_01.htm
http://www.wistv.com/global/story.asp?s=8649027
http://www.fibroscan.co.uk/
chardonney9 - 12 Jul 2008 22:54 GMT >> TX, you should know this by now, but an ultrasound does not show damage to >> the liver cells (although it will show an enlarged liver or a suspicious [quoted text clipped - 22 lines] > > http://www.fibroscan.co.uk/ Thanks for the great links. I will look them all over. Char
Waterspider - 13 Jul 2008 00:36 GMT On Jul 12, 12:28 pm, "Waterspider" <nos...@all.com> wrote:
> "TX-012" <withba...@aol.com> wrote in message > [quoted text clipped - 17 lines] > to > know the extent of their liver damage. Please. I never wrote that, of course. An ultrsound (best = Fibroscan) does not, naturally, allow microscopic examination of *actual liver cells*. What it does provide is useful info as to the condition of the liver as a whole. I don't believe anyone disputes the fact that, biopsies, though imperfect (they are not always representative of the liver as a whole) are _better_ than the best ultrasounds as a diagnostic tool for prospective hep c patients. But ultrasounds/scans are often used in place of biopsies these days for certain groups, for certain reasons.
Sorry, but because you said, "You may not need one. I had an ultrasound, but no biopsy," in a discussion of how to determine extent of liver damage, I assumed you meant she could consider an ultrasound instead of a biopsy. I stand corrected. Confused, but corrected.
Dwight - 11 Jul 2008 02:56 GMT > Is there a reason nobody has responded to my post? Did I do something > wrong? I really need to talk to people who have been through this. [quoted text clipped - 25 lines] >> >> Chardonney The first time I went through tx, I had been HCV+ for about 18 years and didn't have any symptoms that I knew of. When I was first diagnosed I was just told that at some point in my life I had non-A, non-B hep and that was about the extent of it. I had biopsies done 5 and 6 years before ever going through tx. At the time of the first biopsies I already had cirrhosis. I went through a 48 week tx and never responded. I didn't have any sides during the first round. My second round was a little different, not as bad as many, but bad enough. I went through 60+ weeks before quitting, I never even came close to clearing the virus. Now I'm just waiting. I get a little fatigued, but that is about it.
Dwight
Sara - 11 Jul 2008 04:39 GMT > Is there a reason nobody has responded to my post? Did I do something > wrong? I really need to talk to people who have been through this. [quoted text clipped - 25 lines] >> >> Chardonney I was avoiding responding to this note because I felt others here more qualified to answer you than I am. But I can share my thoughts :) First, I think most folks with hep-c have it for many years before being diagnosed because it takes a long time before it starts really taking it's toll on the body. I know in my case I probably had it close to 30 years, and my only real symptoms were that I was tired all the time, and didn't have a lot of energy to do things. I went to several doctors, to try to find out why I was always so tired, and I got some pretty crazy reasons from some of them as to why I was so fatigued, but no one checked me for hep-c until 2005, and that test came back positive. So, I wanted treatment, hoping that would cure me of the fatigue I'd been dealing with for sooooo long.
In my case, treatment worked and I'm currently virus free. I sure hope to stay that way :) But the ONLY way to get rid of the virus at this point in time is to receive the current treatment of pegylated interferon and ribavirin. "natural alternatives" do not cure the virus, and I imagine that many of them can actually be harmful to your liver, which is already having enough problems without you giving it more toxins to deal with.
Many people do work and do the treatment. It's not easy, but it's doable for many heppers. I hope you decide to try the treatments and see how you do on them before deciding that you can't handle working and treatment at the same time.
Sara
metspitzer - 12 Jul 2008 03:06 GMT <snip>
>because it takes a long time before it starts really taking it's toll on the >body. I know in my case I probably had it close to 30 years, and my only [quoted text clipped - 11 lines] >that many of them can actually be harmful to your liver, which is already >having enough problems without you giving it more toxins to deal with. Do you still have fatigue?
I have been clear for over 3 years and I still have fatigue. I have had thyroid tests. They gave me another CMV test. <-- that is some wicked stuff. Iron tests, and a couple of more I can't remember at the moment and nothing showed. I have some good days but most days I am dragging. I have felt a little better lately as you can probably tell by the number of posts.
I also have a terrible skin condition. My skin burns like it is on fire sometimes. Cream helps but it doesn't go away.
I also have constant congestion. Nasal spray helps, but it never goes away.
I think all three are directly caused by the HepC, but I am considered negative.
Sara - 12 Jul 2008 03:45 GMT >(snipped)
> Do you still have fatigue? > [quoted text clipped - 13 lines] > I think all three are directly caused by the HepC, but I am considered > negative. I still have 'some' fatigue, but it's way better than it was before tx... I just don't have the stamina I'd like to have. That said, I do have more energy than I did for many many years, I can walk a mile without getting winded or aching from head to toe, I can play cards for a couple of hours without feeling like I need a nap in the middle, and I can grocery shop AND come home and put the food away, then cook dinner -- all without a long break in between each part.
My skin's not too bad, but I am dryer than I used to be.... mostly my fingertips and cuticles. I've upped my fishoil capsules to 2 a day instead of 1, and it does seem to be helping a bit. and of course, I still drink LOTS of water :)
The congestion -- yes ;) I'm always dealing with sinus issues and coughs -- and I can't take decongestants. Doc says I can take regular allegra or claritin and that helps some, but makes me sleepy :) vicious circle! I've finally learned to take them at night instead of in the morning, d'uh. dunno how much is from tx and how much is just allergies (I live in Michigan, Detroit area, and it's humid, polluted, and pollenated, so who knows) I keep cough drops in my pockets ;)
I'm also about 50 lbs overweight, and my doc feels that if I lose some of that, it would help with the fatigue issues. He's probably right :)
Sara
Waterspider - 12 Jul 2008 00:21 GMT > Is there a reason nobody has responded to my post? Did I do something > wrong? I really need to talk to people who have been through this. Char, I've been through this, and I've been exactly where you are: not sure about anything, scared to death of "chemo" and rationalizing playing with "alternative medicine." The best advice I was given was to stop wasting my money, stop being an idiot, suck it up and do the treatment-- the ONLY treatment that can work. I have no idea what kind of research you're doing, but it's all wrong. So, here are some facts you need to know...
1. There is no alternative medicine cure for hepatitis, none, nada, zilch. In addition to being a waste of money, playing with this is dangerous. You could be doing even more damage to your liver.
2. The only way to determine the extent of your liver damage (which is likely substantial because you've had hep c for decades now), is a biopsy. That's a needle into your liver to take a sample of the tissue. Yes, ouch. But your liver function test are pretty much meaningless until you go into end-stage liver disease. At this point you might survive a year, but the transplant list is twice that long. Get the biopsy. If no one has offered it to you, ask for it nicely and if that doesn't work, then demand it. Your life is at stake.
3. Lose weight. If you're told it's not a thyroid problem then it's not a thyroid problem. So, to lose weight you must eat less and exercise more. No energy to exercise? Eat less. Getting rid of your excess fat will make you feel better, give you more energy and greatly improve your chances of a successful treatment.
4. Most people have only mild symptoms from hep c until end-stage liver disease. Don't kid yourself that this isn't serious because you're still feeling okay. That nasty virus is replecating in your liver to the tune of three billion copies each and every day and destroying liver cells as it does so. Yes, the liver can regenerate itself, but not with hepatitis c and not with cirrhosis.
There ya go. Next step, make an appointment to see a conventional doctor for a referral to a liver specialist to treat your hepatitis c.
Waterspider
chardonney9 - 12 Jul 2008 01:32 GMT >> Is there a reason nobody has responded to my post? Did I do something >> wrong? I really need to talk to people who have been through this. [quoted text clipped - 4 lines] > money, stop being an idiot, suck it up and do the treatment-- the ONLY > treatment that can work. Ever? No person has been cured any other way? http://www.rose-laurel.com/Berksonstudy.htm
I didn't get on this path with only promises. I've talked with people who are cured and others who are on their way.
I have no idea what kind of research you're doing,
> but it's all wrong. So, here are some facts you need to know... > > 1. There is no alternative medicine cure for hepatitis, none, nada, zilch. > In addition to being a waste of money, playing with this is dangerous. You > could be doing even more damage to your liver. There are actually three that I've found. None cause liver damage.
> 2. The only way to determine the extent of your liver damage (which is > likely substantial because you've had hep c for decades now), is a biopsy. [quoted text clipped - 4 lines] > to you, ask for it nicely and if that doesn't work, then demand it. Your > life is at stake. Ok I will do that.
> 3. Lose weight. If you're told it's not a thyroid problem then it's not a > thyroid problem. Not so. Many people go undiagnosed for years because the test they use doesn't actually test the thyroid.
So, to lose weight you must eat less and exercise more. No
> energy to exercise? Eat less. Starve? I don't eat that much as it is.
Getting rid of your excess fat will make you
> feel better, give you more energy and greatly improve your chances of a > successful treatment. It sure would!
> 4. Most people have only mild symptoms from hep c until end-stage liver > disease. Don't kid yourself that this isn't serious because you're still > feeling okay. That nasty virus is replecating in your liver to the tune of > three billion copies each and every day and destroying liver cells as it > does so. Yes, the liver can regenerate itself, but not with hepatitis c and > not with cirrhosis. When I've asked to know more about what is going on I'm told they don't have the time to tell me. It's a huge joke.
> There ya go. Next step, make an appointment to see a conventional doctor for > a referral to a liver specialist to treat your hepatitis c. My general practitioner is head of the local hep c clinic but as I said, I don't get told much of anything. I'm getting medical attention through a county program and honestly it's not so hot. I have a partially numb hand right now because when I cut the palm the emergency room scrubbed it till they severed the nerve. Then when it healed itself they insisted on an operation that took away the feeling again. It's still numb.
I went to the hep clinic and had their "beginners class" but later realized their figures weren't based in reality. And with being a life long sufferer of depression I don't want to go back there again.
I wish I could pay for better care but I can't. That might be why I wasn't offered a biopsy. I dunno....
> Waterspider Dwight - 12 Jul 2008 02:01 GMT >>> Is there a reason nobody has responded to my post? Did I do something >>> wrong? I really need to talk to people who have been through this. [quoted text clipped - 76 lines] > >> Waterspider I don't mean to be negative about this and I mean what I'm about to say in the kindest of ways, but why did you come here and ask for advice or support when you are refusing to believe anything you've been told. Waterspider isn't joking, there isn't another way to cure hep-c at this time. It doesn't work for everyone either, but the alternative methods just don't work. I am tired of watching people die from this disease to sit by and watch another person let it kill them without putting up a fight. I hope you will reconsider the only viable option for a cure and listen to what you are being told.
OK, back into the shadows again.
Dwight (I hate this damned disease.)
TX-012 - 12 Jul 2008 02:14 GMT > >>> Is there a reason nobody has responded to my post? Did I do something > >>> wrong? I really need to talk to people who have been through this. [quoted text clipped - 83 lines] > time. It doesn't work for everyone either, but the alternative methods > just don't work. This is true.
Something else to consider: If you start treatment, and after a week or six or twenty you feel like you cannot continue, _you can always stop._
Today is day 288 for me. That's a reassuring thought---that I am _choosing_ to do this.
chardonney9 - 12 Jul 2008 03:20 GMT >> I don't mean to be negative about this and I mean what I'm about to say >> in the kindest of ways, but why did you come here and ask for advice or >> support when you are refusing to believe anything you've been told. Actually I've not said that I didn't believe anything said that I can think of. Indeed, it's been more the other way around.
>> Waterspider isn't joking, there isn't another way to cure hep-c at this >> time. It doesn't work for everyone either, but the alternative methods >> just don't work. But I know people who used them and it did work. I posted a legitimate published study (and it's not all I know about alternative cures) that proves there are other effective methods and it was turned into "some guy trying to write a book". I haven't even mentioned the oleander soup yet.
> This is true. > [quoted text clipped - 4 lines] > Today is day 288 for me. That's a reassuring thought---that I am > _choosing_ to do this. True!
Tell you what. I will get tested again and then strongly consider it. Are my viral figures relatively high? How high can they go? And where do I fit in on that scale?
Is there another better way to keep track of how sick I am?
Char
TX-012 - 12 Jul 2008 07:05 GMT > Are my viral figures relatively high? How high can they go? And where do > I fit in on that scale?<< IIRC, you said it was currently about 3 million?
http://hepatitis-c.emedtv.com/hepatitis-c/hepatitis-c-viral-load-p2.html
"Generally, the cutoff for high and low hepatitis C viral load is approximately 1 million IU/mL, which is equivalent to 2 million RNA copies/mL. The different numbers are used because differences exist in how the test results are expressed. Results are usually expressed as International Units/mL (IU/mL) or RNA copies/mL.
Most patients with chronic hepatitis C have a viral load between 100,000 and 10,000,000 RNA copies/mL. Expressed as IU, these averages are 50,000 to 5 million IU/mL."
> Is there another better way to keep track of how sick I am?<< Yes. The best way would be a combination of a blood work, medical history and a liver biopsy--or, at the very least, an ultrasound. Viral load is useful to monitor when you're on treatment because how fast viral load drops is an excellent predictor of treatment success, and can tell you if it might be useful to switch medication, increase dosage, or stay on treatment longer than normal (why I plan to stay on tx for 72 week rather than 48).
But the correlation between viral load and degree of liver damage is apparently slim to none, counterintuitive as that may seem...
Sara - 12 Jul 2008 04:00 GMT >>>> Is there a reason nobody has responded to my post? Did I do something >>>> wrong? I really need to talk to people who have been through this. [quoted text clipped - 90 lines] > > Dwight (I hate this damned disease.) Thanks, Dwight. as I was reading these posts I was starting to wonder the exact same thing :)
Sara
metspitzer - 12 Jul 2008 03:12 GMT >> Is there a reason nobody has responded to my post? Did I do something >> wrong? I really need to talk to people who have been through this. [quoted text clipped - 36 lines] > >Waterspider Good answer.
TX-012 - 11 Jul 2008 08:29 GMT > > Suds > > It's nice to hear the truth from those going through it rather than what > the doctors tell you. They admit side effects but gloss over them and go > onto something else as soon as possible.<< I just had another appt with my pain management doctor today for a refill of OxyContin. I hesitate to make broad sweeping statements, but in MY experience, doctors are the people LEAST likely to "get" or "appreciate" or "grasp" what you are going through, no matter the fact that you may tell them in more detail than almost anyone else. Exactly WHY, I do not know...
> Am I right to assume that most of you don't get treatment till you are > pretty sick from the hep c? I know many places won't let you get it > unless you are pretty far along.<< In my case, I was either asymptomatic or mildly symptomatic. I discovered I had hep c while in the later stages of testing to be a kidney donor.
> My GP doctor runs a clinic for hep c and I went to a meeting where we > were told what the treatment was and what would happen should be choose > to go through with it. The good part is that I don't have to wait and I > can start treatment soon as I want to. The bad news is I live alone and > must work to support myself. I don't feel I can do this and go through > the treatment at the same time.<< I am doing exactly this, and 1) I am doing treatment for 72 weeks, and 2) while I have not experienced every side effect in the book (my skin is almost normal, for example), the side effects I have had have been Gawd Awful---severe pain (why I'm on 40mgs oxycodone/day), anemia, neutropenia, exhaustion, brain fog, nausea, etc.
My point is...this is, or can be, VERY VERY hard. But if I can do it, you can probably do it, too. You just trudge through, one day at a time...
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