Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Hepatitis / June 2008

Tip: Looking for answers? Try searching our database.

New Technology May Help Treat Hepatitis B and C

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Jamffer - 25 Jun 2008 22:31 GMT
Whole story.link...
http://www.hepatitis-central.com/mt/archives/2008/06/new_technology.html

"By applying just the right amount of vibration to a virus, scientists
believe that it can be rendered harmless."

"As one of the leading causes of liver disease, both the Hepatitis B and C
viruses remain difficult to eliminate. Although medical technology has
produced some potent medicines to battle these liver-invading viruses, they
are ineffective for a significant percentage of those infected. However,
scientists from Arizona have stepped into an entirely new field of medicine
that proposes a completely different approach to dismantling a virus. By
mathematically determining the frequency by which viruses can be shaken to
death, physics may trump the biological sciences in the quest to safely
eliminate viral pathogens."

=>=>=>=>=>=>=>=>

This sounds great.  Maybe, in a few years, who knows.  This is not a drug so
it might get approved on a faster track, if it works.
Jamffer
greyhackles - 25 Jun 2008 23:52 GMT
>Whole story.link...
>http://www.hepatitis-central.com/mt/archives/2008/06/new_technology.html
[quoted text clipped - 17 lines]
>it might get approved on a faster track, if it works.
>Jamffer

I read the article. Like all similar schemes, this one left me utterly
unimpressed. It describes yet another theoretical method of killing
free-floating virions while having no potential to effect the site of
replication - not dissimilar to the quackery behind "UVC Light treatment" of
HCV.

As has been shown time and time again, simply eliminating free-floating
virions from the blood stream - even to a point below the level of detection -
will not cure a chronic HCV infection. If it did, the first time a person on
therapy received an "undetectable" test result - even using the most sensitive
of the current test methods - that person could immediately stop therapy and
be "cured".

Of course, it doesn't work that way - the replication machinery isn't in the
blood stream - and supposing it takes free-floating virions to maintain those
replication sites would be pretty naive thinking, considering the liver - the
site of the replication - is the most vascular region of the body.

Simply put, don't hold your breath, because it won't work - even if they could
strap a patient down and bombard their entire body with sound waves, light
waves, whatever waves, the little bastids will keep reproducing deep within
the liver, where none of those externally applied forces can safely reach.

And because of that - and knowing a chronic HCV infection can replicate a
TRILLION VIRIONS EVERY DAY - the concept of using this theory to form a
periodic therapeutic measure similar to dialysis (the money-making crux behind
"UVC Light" wackos) is a non-starter. Within hours if not minutes, virions
would be back to pre-treatment levels.

Bottom line: There's hope - and there's false hope. If it isn't a systemically
applied compound or combination of compounds, it ain't gonna work. That's the
only way to disrupt viral replication in situ...

/greyhackles
Jamffer - 26 Jun 2008 01:14 GMT
> >Whole story.link...
> >http://www.hepatitis-central.com/mt/archives/2008/06/new_technology.html
[quoted text clipped - 52 lines]
>
> /greyhackles

They didn't claim any cure.  They are only perusing a new line of research.
It's all hypothesis and it may or may not result in an additional line of
attack, to add to existing standard treatment.  Like with the new
therapeutic vaccines in testing, anything to lower the viral numbers can't
be bad, especially those who do not respond to standard treatment.
I too am skeptical, until real clinical trials have been completed.  Until
then this is nothing, until proven.
I wouldn't call it quackery, to peruse untried avenues of research.  At
least they are doing it scientifically.
So maybe we should cut them some slack, while hoping a shot in the dark
might get lucky.
Jamffer.
greyhackles - 26 Jun 2008 01:34 GMT
>> >Whole story.link...
>> >http://www.hepatitis-central.com/mt/archives/2008/06/new_technology.html
[quoted text clipped - 83 lines]
>might get lucky.
>Jamffer.

I didn't specifically call this "quackery" yet - though I certainly did
associate it with demonstrable quackery ("UVC Light"). Of course, if anyone
ever actually proposes an embodiment of this theoretical work as a therapeutic
device, then it will indeed have crossed the line from "research" to
"quackery". I can wait - though I very much doubt it will ever get that far.

You're entitled to your opinion, and you can cut them all the slack you wish,
but this is not a path to cure, nor a path to any viable maintenance strategy.
Even as an adjuvant to drug therapy, it makes no sense. And I doubt there will
*ever* be any clinical trials, because they won't be able to define any
reasonable expectation as an endpoint or goal, thus there won't be any grounds
for trials. Which is as it should be...

/greyhackles
Jamffer - 26 Jun 2008 01:59 GMT
> >> >Whole story.link...
> >>
[quoted text clipped - 99 lines]
>
> /greyhackles

Although this innovative technology's potential for fighting Hepatitis B or
C is currently in a conceptual stage, the logic behind it is intriguing and
hopeful.  It's too bad that greyhackles has lost all hope for new research.
It's a good thing that the scientists haven't.  To think that something as
simple as resonate sonic waves on the liver might change treatment outcome
is in no way shape or form like UVC light.
greyhackles - 26 Jun 2008 04:01 GMT
>> >> On Wed, 25 Jun 2008 17:31:47 -0400, "Jamffer" <jamffer@hotmail.com>
>wrote:
[quoted text clipped - 92 lines]
>simple as resonate sonic waves on the liver might change treatment outcome
>is in no way shape or form like UVC light.

ahahahahahahaha. Resorting to putting words in my mouth now?
Nice try - let's see if you gain any traction with that ;-)

I am a technologist by trade, for nearly four decades now. I have dozens of
technology-based patents. I'm a huge fan of basic research, and I am *ever*
hopeful for new research in treatments for chronic HCV - research that is
intrinsically sound, that is. This isn't even close to intrinsically sound.
New drugs are where I put my hope and expectations for the future treatment of
chronic HCV.

This "innovative technology" is *exactly* in the same ballpark as "UVC Light"
- that you fail to recognize this exposes a critical flaw in your thinking.
Both are based on treating peripheral blood with "waves" - UltraViolet-C for
the quackery known as "UVC Light" verses sound waves for this "innovative
technology". Both seek to break down virions in the blood stream. The former
has already been shown to be ineffective, the latter will as well - for the
same, intrinsic reason: they do nothing to shut down the viral factories
resident in the liver.

You can mischaracterize my verbal thoughts all you want, but it won't change
the reality. Misplaced hope is a tragedy in the making. I only hope no
significant public funds are wasted in this effort, that could be better spent
on research into treatments that have a realistic chance of actually changing
the course of chronic HCV.

That's all there is to it...

/greyhackles
Jamffer - 26 Jun 2008 16:36 GMT
> ahahahahahahaha. Resorting to putting words in my mouth now?
> Nice try - let's see if you gain any traction with that ;-)
[quoted text clipped - 24 lines]
>
> /greyhackles

"Technologist by trade", typical boast of a probable GED graduate.  And the
technology that you are involved with, is in what specialty?  I hope it's
not drugs because I'm sure you would have called HCV incurable years ago and
went on to work on robots, or the like.
If someone claimed that a fungus could kill bacteria, you would have laughed
at that also, eh?
You and I both know that a researcher needs to try a wide comprehensive
array of things, no matter how strange, to find the needles in the giant
haystack.  A one in a million shot could take millions of hours to find but
that one or two in a million would seem like a miracle to suffers, who'd
rather die of old age, instead of a virus.
A few things like milk thistle have been tested in controlled studies and
show no remarkable benefit to HCV.
Controlled studies are the judge here, not me or you.  Cheer up.
Jamffer
Sara - 26 Jun 2008 17:58 GMT
>> ahahahahahahaha. Resorting to putting words in my mouth now?
>> Nice try - let's see if you gain any traction with that ;-)
[quoted text clipped - 56 lines]
> Controlled studies are the judge here, not me or you.  Cheer up.
> Jamffer

Jamffer, are you on treatment right now, or are you looking for that elusive
'miracle cure' still?
Last time you were posting a lot, you were full of it, and seems you still
don't know your butt from a hole in the ground....  but of course you'll
continue to blather nonsense rather than to listen to anyone who has their
sh.t together like Grey has.

It's irritating to read about things that really have no chance of going
anywhere -- why don't you try to research some REAL potential breakthroughs
in HepC treatment instead of pushing snake oil here on people who deserve
better.

Sara
Jamffer - 26 Jun 2008 19:34 GMT
> >> ahahahahahahaha. Resorting to putting words in my mouth now?
> >> Nice try - let's see if you gain any traction with that ;-)
[quoted text clipped - 70 lines]
>
> Sara

Sorry, but I don't rule out anything before it's proven or disproved in the
real world.  I am the first to be skeptical about any test tube results.
The real world of controlled studies, is the judge.  I never will advocate
anything that has not been proven, and never will.  I don't know where you
got that impression.
I started treatment, but was ordered to stop until (possible ulcer) was
cleared up. (Pegasys-Riba),  which I think was working, because my lymph
nodes became normal, in only day after start of tx.  I don't think any
(natural) treatment is of much benefit.
Cheer up.  I promise to keep quiet about very early research, but some need
hope for what seems like hopelessness.  There are a few phase 3 promising
trials in the pipeline, as you all have probably seen.
Jamffer
TX-012 - 26 Jun 2008 21:07 GMT
even if they could
> strap a patient down and bombard their entire body with sound waves, light
> waves, whatever waves, the little bastids will keep reproducing deep within
> the liver, where none of those externally applied forces can safely reach.

You means I will has to stop curing my hep c by sitting on top of za
washing machine?

ohdamn
Jamffer - 26 Jun 2008 21:38 GMT
>"TX-012" <withbacon@aol.com> wrote in message
news:267402df-360f-42cf-b07e-79ba5b35ca00@j33g2000pri.googlegroups.com...
even if they could
>> strap a patient down and bombard their entire body with sound waves, light
>> waves, whatever waves, the little bastids will keep reproducing deep within
>> the liver, where none of those externally applied forces can safely reach.

>You means I will has to stop curing my hep c by sitting on top of za
>washing machine?

>ohdamn

Sound waves will penetrate miles of sea water (through liquid).  Maybe
killing every cell in your body, might be a side effect.  This idea will
probably be put into the city dump of tried and failed ideas, to combat
viruses.
I want them to discover that having sex with three cheerleaders at once,
will cure HCV.  But you need to take them twice a week, for them to work.
Jamffer
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2009 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.