Paxil

Thread view:

Enable EMail Alerts

Start New Thread

Thread rating:

Rusty - 05 May 2008 17:46 GMT

Hello All,

I was just given a prescription for Paxil 20Mg (Paroxetine HCL) and want to
know if this is really bad for the liver.
I have HCV and a non-responder. As far as I know, my liver damage is "mild"
at this stage. I'll know more after my 5 year biopsy in a couple of months.

Anybody here use Paxil? Any comments about it?

Thanks for your help

Reply to this Message

tom - 05 May 2008 21:39 GMT

> Hello All,
>
[quoted text clipped - 6 lines]
>
> Thanks for your help

Liver Function Tests: In placebo-controlled clinical trials, patients
treated with PAXIL exhibited abnormal values on liver function tests at no
greater rate than that seen in placebo-treated patients. In particular, the
PAXIL-versus-placebo comparisons for alkaline phosphatase, SGOT, SGPT, and
bilirubin revealed no differences in the percentage of patients with marked
abnormalities.

~~~~~~~~~~~~~~~~~~~~~~~~~~~~

Specific Populations: Renal and Liver Disease: Increased plasma
concentrations of paroxetine occur in subjects with renal and hepatic
impairment. The mean plasma concentrations in patients with creatinine
clearance below 30 mL/min. was approximately 4 times greater than seen in
normal volunteers. Patients with creatinine clearance of 30 to 60 mL/min.
and patients with hepatic functional impairment had about a 2-fold increase
in plasma concentrations

~~~~~~~~~~~~~~~~~~~~~~~~~~~~

http://www.healthyplace.com/medications/paroxetine.asp

Reply to this Message

TX-012 - 06 May 2008 01:37 GMT

> Hello All,
>
[quoted text clipped - 6 lines]
>
> Thanks for your help

It's not bad for your liver. I've used it. What are you being Rx'd
Paxil for, and why Paxil?

Reply to this Message