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Medical Forum / Diseases and Disorders / Hepatitis / December 2007

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Sick Boy - 29 Nov 2007 02:29 GMT
Just wanted to write a short post--albeit a belated one--about my
end-of-Tx results. I haven't got the time to repeat my particulars
right now, except that my HCV viral load was 2.7 million at the
beginning, genotype 3b, high ALT/AST, but otherwise normal tests. I
had been infected in about 2000. I began treatment on May 18, 2007,
with no biopsy, ALT/AST went back to normal at week 2 and has been
normal ever since, undetectable VL at week 4 and 12.

So, I had my last lab test on October 31st, a few days after my final,
24th shot of Peg-Intron. Hg is still slightly lower, but everything is
normal, including ALT and AST. I was happy to find out that my VL was
still undetectable--as usual, the first did the test with the 50 IU/ml
(or whatever the units are), and forwarded the sample for a more
sensitive test, which showed that I had <5 IU/ml...as far as the test
is concerned, undetectable. The Dr. told me to come see him in 3
months. I'm keeping my fingers crossed.

Life is sure funny post-Tx, isn't it? I've read some posts here on the
subject. I didn't have as severe side effects as many other people
have reported, so maybe the difference is not as profound for me.
Still, I guess there's a pressure of sorts to live my life the way I
want it, rather than the way is expected, and not worry about future
so much. <g>

I wanted to ask if anyone has experienced aches/tenderness in the
liver area even after successful EoTx response, and what it can
possibly mean. It worries me now more than when I knew I had a couple
of millions of that stuff per ml of my blood. Maybe I'm paying too
much attention to the way I'm feeling.

I just wanted to drop in and share this. Any recommendations specific
for post-Tx period, perhaps? Also, I've been experiencing some joint
pain, too--can it be that interferon is lingering in my body 5 weeks
after the last shot?
I hope everyone is doing well. Thanks for all your support. For the
people who recently finished, or are finishing up their treatment (I
know that most people are not as lucky as I was, doing a year of Tx),
my thoughts are with you.
Good luck,
Signature

Sick Boy

dBo - 30 Nov 2007 21:23 GMT
> I wanted to ask if anyone has experienced aches/tenderness in the
> liver area even after successful EoTx response, and what it can
> possibly mean. It worries me now more than when I knew I had a couple
> of millions of that stuff per ml of my blood. Maybe I'm paying too
> much attention to the way I'm feeling.

Well now THERE is something many of us have questioned as well. I
never had any discomfort prior be the surpries diagnosis - after tx
began it became very pronounced and when I asked my BLCD he said "well
of course its uncomfortable there's a WAR going on in there right
now!"  The discomfort stayed with me thru 38 weeks of Tx and continued
on thur the past year post tx. I recently discussed this with him at 1
yr post tx checkup (still virus free hooray!) Some of the things we
discussed were even the possiblity that I wondered if it is all in my
head... and like he said, you become overly sensitized by TX etc. I
even laughed and told him that I keep trying to tell myself that the
discomfort may be coming from my liver regenerating itself and growing
all those new cells now that it is healthy again, haha! Who knows,
right? He suggested if I wanted to we could order an MRI, but I said I
would wait and see how it goes... I felt the same way, worrying about
the continued discomfort post tx even knowing I was cured.

If you read up on Live transplants where a healthy donor donate half
their liver it is astounding how quickly the healthy donors half
remaining liver regenerates itself to full sized...seems like that
*might* cause some "discomfort" as it is growing bigger again day by
day. Why would this not be the same, if you had a really unhealthy
liver going into tx, beat the f*ing dragon, and your liver started
growing back again once it was getting healthy again...??

Ironically, since the 1 yr post tx discussion with my BLCD and
reassurances that I am "fine" now, and my liver has probably reverted
all the way back even to possibly stage 1 from stage 3, the
"discomfort" seems to be less and less noticeable. Go figure! Maybe I
jsut needed that reassurance to quit worrying about it so much, or
maybe and "unhealthy" liver regenerates slower than a "healthy" one,
and enought time has gone by now that things are that much better.

I don't have an answer for you, but those are my thoughts. :)
TX-012 - 01 Dec 2007 07:49 GMT
. Any recommendations specific
> for post-Tx period, perhaps? Also, I've been experiencing some joint
> pain, too--can it be that interferon is lingering in my body 5 weeks
> after the last shot?
> Sick Boy

I doubt it's the interferon itself after 5 weeks, but rather the
effects of the interferon. For example, when I slam my 40,000 IU of
EPO, it clears the body within a few days, but the maximum hematocrit
elevation from that shot takes a few weeks to appear.

My take is that interferon is basically catabolic and pro-inflamatory
with respect to soft tissue, in general. While "ideally" this might be
a splendid time for a cycle of certain anabolic steroids + HGH, that
would be difficult (not impossible) and costly to obtain legally, and
doing this otherwise would cause you to break the law, which as we all
know is only done by criminals, and criminals are bad. Because they
break the law;)

Sooo. If you want some generic post-tx joint pain Rx using OTC shite,
here goes. Take both of the following for 8 weeks:

4 caps/day of http://www.nutraplanet.com/product/primaforce/cissus-40-ketosterones-120-caps.html

10 caps/day of http://www.nutraplanet.com/product/nutraplanet/bulk-fish-oil-caps-1000-softgels.html

Now, if you're interested in an OTC pro-hormone cycle, lemme
know...even post-ban, there are still some useful, mild substances out
there WRT joint health, such as the boldenone precursor...
 
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