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Medical Forum / Diseases and Disorders / Hepatitis / September 2007

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amzolt - 26 Sep 2007 16:23 GMT
So...

At week 12 I found out, through my Primary Care Doc at the VA, that my
load was down from 1.5 MIl to about 600.

At week 16 I saw one of my IC team and they clarified:

At 12 weeks, my load was listed as <625.

This, he explained, is the way they write "cleared" since, even if it
was 0, they'd still write <625...

He also said my red count was back to normal so I could cut the Epogen
down to every other week.

Thing is, since I decided to forgo the Epogen shot last week, each day
has seen a strong increase in fatigue...

Just shot the Interferon and the Epogen so, we shall see......

~ Alex
greyhackles - 26 Sep 2007 16:55 GMT
>So...
>
[quoted text clipped - 17 lines]
>
>~ Alex

Well that *is* much better, isn't it? :-)

From what I've read here over the years it is not unusual for labs to
essentially parrot the sensitivity of the test instead of an actual count if
the sample doesn't cause a positive test result.

I really wish they'd smarten up on that - how hard is it to write "below
threshold"? My lab, otoh, listed the test sensitivity (>5 IU/ml) and added
"not detected" - together, very easy to understand.

What that also tells you, btw, is they're not using one of the more sensitive
tests, for whatever reason, and they're not doing you any favors with that...

As for the fatigue, are you *really* drinking enough water?

Cheers - and hang in there - you have extra motivation now :-)

/greyhackles
amzolt - 26 Sep 2007 19:42 GMT
> What that also tells you, btw, is they're not using one of the more sensitive
> tests, for whatever reason, and they're not doing you any favors with that...

Should I demand a more accurate test? He claimed the <625 meant I was
"negative"...
greyhackles - 26 Sep 2007 21:37 GMT
>> What that also tells you, btw, is they're not using one of the more sensitive
>> tests, for whatever reason, and they're not doing you any favors with that...
>
>Should I demand a more accurate test? He claimed the <625 meant I was
>"negative"...

Clearly, if the test sensitivity threshold is 625 IU/ml, and there is no
observed reaction, the test result is called "negative", aka "undetectable".

And that's good, certainly. Don't mistake my point here. I'm simply relating
the fact that there are modern viral load tests that are two orders of
magnitude more sensitive (eg: 5IU/ml) and you have to wonder why one isn't
being used.

The difference is cost, of course, but that may not be the reason why your doc
is still using that particular test. He may simply not be aware that there are
more sensitive tests available. Who knows? You might ask him when you get
ready for your end-of-treatment test to use the more sensitive test and see
what response you get...

Cheers

/greyhackles
amzolt - 26 Sep 2007 22:15 GMT
>You might ask him when you get
> ready for your end-of-treatment test to use the more sensitive test and see
> what response you get...

Well, I ask about it in two weeks and we'll see what happens.
Thanks.

~ Alex
Russian - 29 Sep 2007 20:32 GMT
> As for the fatigue, are you *really* drinking enough water?

That was probably the main thing I never got right... but when I started
feeling that wipe-out feeling, at least I knew to down a full bottle of
water, and I'd be feeling better again in 5 minutes.
amzolt - 30 Sep 2007 11:41 GMT
>when I started
> feeling that wipe-out feeling, at least I knew to down a full bottle of
> water, and I'd be feeling better again in 5 minutes.

Yet even more water...

Yet, my water intake hasn't changed these past months but the Epogen
shot did...
Should I ignore that fact?
 
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