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Medical Forum / Diseases and Disorders / Hepatitis / July 2008

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Can anyone shed some light on test results?

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Mel - 06 Aug 2007 16:54 GMT
Hi,
I'm new to this group, and was wondering if anyone can
explain a few things I have on my test results that I don't
understand???
The specialist said the results were bad, but didn't go into any
detail.
She was in too much of a hurry....(maybe she was running late for her
compassion & personality implant surgery).

My levels -
ALT - 446
AST - 220
GGT - 143

FERRIAN - 350

INSULIN LEVEL - 36
C-PEPTIDE - 1.87

HEP C RATIO - 5.79

HEP C NAD - POSITIVE
HEP C NAD COMMENTS - (All that was in this one was - The lower limits
of....

Does anyone know how bad this looks???
If anyone can help me with any of these, it would be much appreciated.

Thanks in advance,
Melissa
Cactus Jammies - 06 Aug 2007 17:09 GMT
Melissa,
  First of all, welcome to the support group.  You will find all kinds of
things going on in here.  It is always a bit sad to have to welcome someone
new, but at least they reached out for support and to have vexxing questions
answered asap.

  Your specialist is right, depending on what she was comparing your liver
numbers to.  Have you any other sample results than these, from earlier in
your life?
 Hep C is a progression of a condition and your ALT AST numbers although
high, may not be truly and overall indication of your liver health, which is
what you should be concerned about now, wanting to get cured.  Liver health.
I would say that she is probably lining you up for a biopsy which is a assay
taken from the top area of your liver, by long needle.  It doesn't hurt.
The assay will be analysed to see what stage of  scarring your liver has
because of the virus, as well as discover if you have steatois (fatty liver,
but skinny people have steatosis, too).

Stick around Mel, it is not galloping through you, it is very slow

cactus jammies
> Hi,
> I'm new to this group, and was wondering if anyone can
[quoted text clipped - 26 lines]
> Thanks in advance,
> Melissa
Mel - 06 Aug 2007 18:45 GMT
On Aug 7, 2:09 am, "Cactus Jammies" <cactusjamm...@retinal.circus.orb>
wrote:
> Melissa,
>    First of all, welcome to the support group.  You will find all kinds of
[quoted text clipped - 48 lines]
>
> - Show quoted text -

Hi,
Thanks for your response.
I will be getting a biopsy sometime soon.
I have to wait for the hospital to call me to set up appt.

This was my first comprehensive test.

I have had regular tests over the years, I seem to have contract hep c
over christmas.

Various tests after chrissy showed abnormal liver numbers.

So I got another hep c test, and it came back pos.

I had a test probably eight months prior, and it was neg....they all
have been. Till this one anyway.

I've had an ultrasound...it came back normal...

Thank you for the Welcome...

Melissa
Cactus Jammies - 06 Aug 2007 19:56 GMT
Mel,
 It sounds like you may be having an acute reaction then.  A reaction in
which your body is still fighting the virus and in about 20% of the cases
overall, I think the body does succeed.  Not sure of actual percentage.  Are
you sure it is Hepatitis C and not some other Hepatitis?

cj

> On Aug 7, 2:09 am, "Cactus Jammies" <cactusjamm...@retinal.circus.orb>
> wrote:
[quoted text clipped - 82 lines]
>
> Melissa
Janice - 19 Jul 2008 18:38 GMT
You stated that a liver biopsy " does not hurt"! What planet was your biopsy
done?
> Melissa,
>   First of all, welcome to the support group.  You will find all kinds of
[quoted text clipped - 47 lines]
>> Thanks in advance,
>> Melissa
Sara - 19 Jul 2008 19:59 GMT
> You stated that a liver biopsy " does not hurt"! What planet was your
> biopsy done?
>(snipped)

My biopsy didn't hurt.  It was 'uncomfortable' but not painful.   Scary,
more than anything.  I was nervous so it was not a comfortable procedure for
me.   But it wasn't really a painful experience -- the needle shoots in and
out so fast you hardly know it happens (except my ribs are very close
together, so there was a 'sound' thing going on that was freaky for me)

It's the hours you have to spend lying on your side afterwards that will get
to you -- you feel 'fine' and you want to be out of there!   I read.....
not the easiest thing to do lying on your side lol

Sara
Waterspider - 19 Jul 2008 22:40 GMT
> You stated that a liver biopsy " does not hurt"! What planet was your
> biopsy done?

My biopsy did not hurt at all. In fact, I wasn't even aware of it being
done. Happily, it was done at the same time as a gall bladder removal, so I
was unconscious :-)
bob - 28 Jul 2008 00:41 GMT
> You stated that a liver biopsy " does not hurt"! What planet was your
> biopsy done?

Mine was done on earth and was completely pain free.
Kozure Ookami - 07 Aug 2007 00:40 GMT
>Hi,
>I'm new to this group, and was wondering if anyone can
[quoted text clipped - 26 lines]
>Thanks in advance,
>Melissa

Hmmm, did your doctor say you tested positive for hepatitis C?  Hep C
NAD - No Abnormalities Detected - POSITIVE.  Normally positive next to
Hep C means the virus was detected presumably in an antibody test
which is probably the case here.  Testing positive for hep c
antibodies doesn't mean you have chronic hepatitis C but those liver
function tests (ALT,AST,GGT) are very high above normal so it would
seem likely unless something else is up with your liver.  FERRIAN?  I
assume you mean ferritin and that's pretty high for a female.  That
relates to iron levels and is often elevated when someone has
hepatitis (inflammation of the liver).  

Regarding the insulin...
"A 'normal' insulin level would be less than 30uU/ml. A fasting level
should be nearly undetectable. If you are in Europe, the level may
have been run in pmol/L. If this is the case, the level should be 35 -
145 pmol/L. Again the fasting level should be at the low end. "
(from http://forums.obgyn.net/pcos/PCOS.0003/0415.html)

So, if I'm interpreting your results correctly they would normally do
a quantitave test to measure the viral load (how many of the virii
counted per some unit of blood), maybe a qualitative test which is
more sensitive than the quantitative and just says whether or not the
virus was found.  Last but not least they determine what genotype of
the virus you have which tells you whether you have the tougher to
treat variant of the virus or one of the easier to treat variants.  

Normally you also get an imaging like ultrasound or CAT scan of the
abdomen so they can look for any abnormalities there and a biopsy
which is usually the one that tells what kind of condition your liver
is in.

But you also said in a follow up note that you believe you acquired
hep C in December but I'm not clear on why you thought that.  What
brought about these tests?  Are you having symptoms of some sort?  How
do you think you acquired the disease if you don't mind telling.
People often have this disease for decades and don't know about it.

Don
Kozure Ookami - 07 Aug 2007 01:08 GMT
>But you also said in a follow up note that you believe you acquired
>hep C in December but I'm not clear on why you thought that.  What
[quoted text clipped - 3 lines]
>
>Don

Ok, I had another look at that follow up note and see that you have
had some recent prior tests that were negative and already had the
ultrasound.  Did you already have the viral load and genotype tests as
well?  Were you having some symptoms that were the reason for all that
testing?  I wonder if a biopsy is necessary if you've only had hcv for
7  months.  Especially if you are younger.

Don
Mel - 07 Aug 2007 12:11 GMT
> >But you also said in a follow up note that you believe you acquired
> >hep C in December but I'm not clear on why you thought that.  What
> >brought about these tests?  Are you having symptoms of some sort?  How
> >do you think you acquired the disease if you don't mind telling.
> >People often have this disease for decades and don't know about it.

> >Don
>
[quoted text clipped - 4 lines]
> testing?  I wonder if a biopsy is necessary if you've only had hcv for
> 7  months.  Especially if you are younger.

Hi Don,

When I was younger, I indulged in risky behaviours.
And throughout my life, (not any more) had some issues with alcohol -
over
indulgence (binge drinking), usually leading to unprotected sex.
Hence the regular "Usual Suspects" tests.
I always have had the Hep C test, if I was having the HIV one, may
aswell,
and wasn't sure whether it was an STD or not.

Anyhow, for the last 5 years or so, I have suffered depression....not
always
managed properly - on my part. And last year, got stuck into the grog
a fair bit.
Over Christmas, I went through some very stressful financial issues
(mainly sorting
them out), and had to do the whole - tell the family thing, which was
very upsetting
to me, cause I didn't want to disappoint them.

One night out, intoxicated, I ran into an old "user" friend, and ended
up visiting old
territory. I didn't share the needle, but he did it for me.
He has been a long time user, it had been 15 years since I saw him
last, and
he was on the methadone, and still using aswell.
I knew he would have to have hep c, but I didn't share, so thought I
would be safe.

What happened was unrelated really, a slight indiscretion, and that
was what I
was worried about.

I'm a bit of a hypercondriac and always watch for signs of nasty
diseases.

About 1 week later, I got a throat infection, that lasted about 4
weeks, then it turned into
what I think was pleurisy. I basically had flu like symptoms, for an
extended period of
time, without being able to put a name to it.

I had some regular blood tests about 1 month after that, and they
showed abnormal liver
activity....can't find it at the moment. Straight away, (I was already
worried anyway) I thought
there was something to it.

Keep in mind, I still thought it was possible to get it through sex.

So a week later, I went and got the hep c and hiv test. It basically
showed positive
for hep c antibodies, roughly three months after the incident.

After researching on the net, I found out just how easy it is to get
it during
IV drug use. He could have just had some minute blood on his hands....
Which is the likely case, as he did me after him.

I am ashamed to put this on here, but as you can see, I'm an honest
person, and
an open book. I'll pretty much tell anyone anything they want to know.
But that doesn't mean I'm proud of my actions, or lack of "life lesson
learning" skills.

These things usually catch up with us one day, you can't be lucky
forever.
Especially when you keep doing the wrong things.

I was just blown away though, as I really didn't think it was that
easy to catch.

Well I am glad to say, that I did not contract HIV.

My Genotype is 1 - that's it, i'm sure it's sposed to have a letter
after it.....but that's all that's
on my report.
Also, they didn't do a viral load test, she couldn't tell me why, but
she ordered
one from some left over blood. (Hopeless.....)

I'm sure i was acute when I got the test, because I was extremely
fatigued, couldn't
stay awake to save my life some days, and had trouble regulating my
temperature.

Also, another sure sign is the urine....(nice colour and smell - NOT).
That really scared me.

I know I'm not acute now, as I only get sick (which is usually sleepy)
after I have misbehaved.

So maybe the blood I got her to take a couple of weeks ago will show
better results.

So there's my sorry and long winded tale (apologies for putting you to
sleep:))

Regards,

Mel.....

> Don
Kozure Ookami - 08 Aug 2007 10:04 GMT
sults.

>So there's my sorry and long winded tale (apologies for putting you to
>sleep:))
>
>Regards,
>
>Mel.....

Indiscretions with needles has landed quite a few of us in here.
Unless that needle was being used for the first time it wouldn't have
been safe from HCV contamination.  The HCV virus unlike the HIV virus
can survive a long time outside of the host I've been told.  That's
why you can get it from toothbrushes etc.  

Your story makes me feel kind of sad though it is not unfamiliar.
Mistakes sometimes are costly.  Fortunately, this particular disease
is not necessarily the worst.  Unfortunately, you got one of the
tougher to treat variants which is also the one most people get in the
US, UK, Europe, Australia, Japan, and probably other places.  Still,
it can be beaten.  People do it every day.  It can be a tough decision
whether to  because the treatment carries some risks.  Either way this
is a pretty good place to talk things over with people in the same
boat or who have beaten the virus.  I slew my dragon years ago.  I had
it easy though being a genotype 2.  Still, the treatment was no
picnic.

One thing I've heard is that getting the virus later in life is worse
than getting it when younger because liver damage can occur faster.
I'm not sure what the details are but that might be something to
discuss with the doctor.  Also, that it is easier to treat if you get
it early in the infection period but I don't know how early that is.
Just in the acute phase or what.    Did your doctor say you would need
a biopsy this soon?  I wonder if significant damage could occur so
soon.  

Anyways, welcome to the group and I hope you find it useful.  We all
have issues going on in our lives at one time or another and I hope
your situation improves very soon.  

Don
 
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