Sorry, there is no treatment, there is no cure.
If you have hepaptits c, peg-interferon+riba treatment may diminish your
liver damage, your stage of fibrosis.
You can live for a long time with fibrosis/cirrhosis, if you look after
yourself. That mean absoluely no alcohol and taking care of yourself in
terms of a healthy diet, moderate exercise and avoiding toxins to your liver
through other means such as being inhaled and absorbed through your skin.
Beware of snake-oil salesmen and "miracle cures" that do you no good and
maybe even cause serious harm.
Your condition is serious. Do some research, take care of yourself, stick
around here... you'll get better advice than you would from most doctors. It
would be helpful if you told us more about your condition.
Good luck, and hang in there.

On Mar 2, 11:32 am, Jack.Kir...@gmail.com wrote:

They are not positive yet .. but reducing the iron in the liver is
showing promise.

<<snip>>
Cirrhosis (and possibly fibrosis in other organs) may be reversible if
underlying profibrotic conditions are eliminated.
<<snip>>

BRIEF COMMUNICATION
Reversibility of Cirrhosis in Patients Cured of Thalassemia by Bone
Marrow Transplantation
Pietro Muretto, MD; Emanuele Angelucci, MD; and Guido Lucarelli, MD

7 May 2002 | Volume 136 Issue 9 | Pages 667-672

Background: Cirrhosis is a well-known complication of thalassemia
major. In this context, it is a consequence of iron overload and
hepatitis C virus infection and generally seems to be irreversible.

Objective: To determine whether cirrhosis in thalassemia major can be
reversible.

Design: Retrospective study.

Setting: Bone Marrow Transplantation Unit and Pathology Service,
Pesaro Hospital, Pesaro, Italy.

Patients: 6 patients who developed liver cirrhosis before or after
their thalassemia was cured by bone marrow transplantation (age at
transplantation, 11 to 25 years). After diagnosis of cirrhosis, the
patients received iron depletion and antiviral therapies.

Measurements: Each liver biopsy specimen was coded. A liver
pathologist and a member of the transplantation center with expertise
in hepatopathology graded the specimens by using the Ishak staging and
grading systems. Neither knew the patient's identity or the sequence
of biopsy with regard to the time of treatment.

Results: After the patients received iron depletion and antiviral
therapies, liver biopsy specimens showed impressive reduction in liver
iron stores. In 4 patients, iron removal was complete. Serum
aminotransferase levels decreased in all patients and normalized in 5;
histologic inflammatory activity decreased in all patients and
disappeared in 2. Follow-up biopsies showed regression of incomplete
or definite cirrhosis in all patients; 3 patients had presented with
portal fibrosis without bridging, and the others had portal fibrosis
and portal-to-portal bridging. Several biopsies and the presence of
many portal spaces confirmed the diagnosis of cirrhosis; follow-up
biopsies confirmed regression of cirrhosis.

Conclusion: In some patients in whom bone marrow transplantation has
cured thalassemia, cirrhosis may be reversible after iron removal
treatment.

Editors' Notes

Context

Thalassemia is usually accompanied by conditions that cause cirrhosis,
such as iron overload and hepatitis C virus (HCV) infection.
Allogeneic bone marrow transplantation can cure thalassemia, and iron
removal and treatment of HCV infection after transplantation may
eliminate stimuli for fibrosis. Whether cirrhosis can recede after
treatment is unknown.

Contribution

Six selected patients with thalassemia cured by bone marrow
transplantation had liver biopsies before and after treatment. Biopsy
specimens were evaluated by pathologists blinded to patient
identification and sequence of biopsy. Cirrhosis improved
substantially in all patients.

Implications

Cirrhosis (and possibly fibrosis in other organs) may be reversible if
underlying profibrotic conditions are eliminated.

-The Editors

Who loves ya.
Tom

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