Home | Contact Us | FAQ | Search & Site Map | Link to Us
Sign In | Join | Other 45 Sites in Network
Home
Discussion Groups
General
GeneralCardiologyVisionDentistryPharmacyLaboratoryNutritionAlternative
Diseases and Disorders
AIDSAlzheimer'sArthritisAsthmaCancerBreast CancerDiabetesEpilepsyGlaucomaHepatitisHerpesLupusProstate BPHProstate CancerProstatitisSinusitisTinnitus

Medical Forum / Diseases and Disorders / Hepatitis / January 2007

Tip: Looking for answers? Try searching our database.

Katie

Thread view: 
Enable EMail Alerts  Start New Thread
Thread rating: 
Mom - 20 Jan 2007 11:21 GMT
Hello all. Back for more input. Katie has been having a battery of tests run
to see if she is a candidate for treatment. I have got to give this doctor
one thing for sure.......he is very thorough which makes me feel better. He
wasn't going to recommend treatment unless he thought she was ready for it.
I think he would have preferred like so many of you thought to wait for
something better. She has had doctor appointments every week now for over a
month from bloodwork to eye exams to an ultrasound and more.

Today the blood results came back and totally shocking to both Katie and
myself they came back as her having genotype 3A! She was originally
diagnosed with 1A as many of you will remember. If my memory is correct 3A
is a shorter treatment and has a higher cure rate? Should she have a third
test to confirm genotype?

When she was first diagnosed her LTF's? were a little over 2 million. They
are now over 8 million. The doctor has decided she is a good candidate for
treatment. The next step is scheduling a biopsy. The closer this gets the
more anxious I get but that is neither here nor there as it is not me going
to go through it. I will be there for her that is for sure.

Any words of wisdom? Thomas? Elmo? Paul? WS? Anyone? Come out, come out
wherever you are.

Mom

--------------------------------------------------------------------------------
elmoemerson@webtv.net - 20 Jan 2007 15:16 GMT
If indeed Katie is a geno 3a, that'd be very good news for the reasons
you mentioned.  Like you though, I'd probably want to confirm the test
with one more.  Can't hurt anything.
LFT's are 8 million.  ahahahahahahaha!!!  Sorry, Mom.  I couldn't help
but laugh.  I think you're confusing LFT's with viral load (pcr).  If
her LFT's were that high, she'd be a scientific marvel of some sort.
They'd wonder how she was still walking and talking.  
With a viral load of 8 million, that's on the high side of mid-range.
But if she's a geno 3a, probably not a big deal.  Viral load fluctuates
and maybe they caught it on the high end of the cycle.  There's a good
chance that her previous test wasn't able to accurately measure viral
load that high.....newer and different tests can more accurately
determine viral load on the upper end of the scale.      
It looks to me like Katie is bound and determined to get this battle
over with now as opposed to later.  A shorter tx duration (3a) is alot
more doable.  I'm curious to see what her biopsy results are. In any
case, I'm on the support bandwagon for Katie.  Give her a hug for me.
elmo
////////////////
Hello all. Back for more input. Katie has been having a battery of tests
run to see if she is a candidate for treatment. I have got to give this
doctor one thing for sure.......he is very thorough which makes me feel
better. He wasn't going to recommend treatment unless he thought she was
ready for it. I think he would have preferred like so many of you
thought to wait for something better. She has had doctor appointments
every week now for over a month from bloodwork to eye exams to an
ultrasound and more.
Today the blood results came back and totally shocking to both Katie and
myself they came back as her having genotype 3A! She was originally
diagnosed with 1A as many of you will remember. If my memory is correct
3A is a shorter treatment and has a higher cure rate? Should she have a
third test to confirm genotype?
When she was first diagnosed her LTF's? were a little over 2 million.
They are now over 8 million. The doctor has decided she is a good
candidate for treatment. The next step is scheduling a biopsy. The
closer this gets the more anxious I get but that is neither here nor
there as it is not me going to go through it. I will be there for her
that is for sure.
Any words of wisdom? Thomas? Elmo? Paul? WS? Anyone? Come out, come out
wherever you are.
Mom
----------------------------------------------

http://community.webtv.net/elmoemerson/DocElmosHepFile

http://community.webtv.net/elmoemerson/TheFamilyAlbum
Dwight - 20 Jan 2007 16:27 GMT
> If indeed Katie is a geno 3a, that'd be very good news for the reasons
> you mentioned.  Like you though, I'd probably want to confirm the test
[quoted text clipped - 42 lines]
>
> http://community.webtv.net/elmoemerson/TheFamilyAlbum

Hi Mom, I agree with Elmo. Get the test redone to check the type. If she
is 3A good for her. Whatever she decides to do tell her she has my
support as well. 24 weeks of tx and a better success rate sounds
terrific. My best to both of you.

Dwight
Thomas Wagner - 20 Jan 2007 15:37 GMT
>Today the blood results came back and totally shocking to both Katie and
>myself they came back as her having genotype 3A! She was originally
>diagnosed with 1A as many of you will remember. If my memory is correct 3A
>is a shorter treatment and has a higher cure rate? Should she have a third
>test to confirm genotype?

That's very surprising - yes, I'd absolutely request a third test, since
genotype determines treatment duration, and you don't want just 24 weeks
when her genotype is 1 instead of 3. I'm not sure if it's even possible,
but could she be infected with two genotypes at once? Grey?

>When she was first diagnosed her LTF's? were a little over 2 million. They
>are now over 8 million. The doctor has decided she is a good candidate for
>treatment. The next step is scheduling a biopsy. The closer this gets the
>more anxious I get but that is neither here nor there as it is not me going
>to go through it. I will be there for her that is for sure.

The 8 million is probably her viral load, and that can fluctuate quite a
lot. It's not necessarily a sign that things are worse. The real measure
is the biopsy. I'd doubt that she has major damage after such a short
time, but you never know.

If it turns out she really is genotype 3, then I'd recommend she do the
treatment even if she has no damage. 24 weeks are usually doable (no
walk in the park, but doable) and the success rate for geno 3 is around
80-90%. But the genotype matter has to be absolutely clear first.

Thomas
P.S.: Yes, it was your attachment that caused your posts to disappear.
Most servers will reject posts with attachments in non-binary groups.
Signature

To reach me, complete my last name in the address.

greyhackles - 20 Jan 2007 16:23 GMT
>>Today the blood results came back and totally shocking to both Katie and
>>myself they came back as her having genotype 3A! She was originally
[quoted text clipped - 6 lines]
>when her genotype is 1 instead of 3. I'm not sure if it's even possible,
>but could she be infected with two genotypes at once? Grey?

Absolutely, yes, co-infection with multiple genotypes is apparently common
enough in the IVDA community that it has to be considered. I'm not familiar
with this young lady's history but if she is/was IVDA+ it would be a *really*
good idea to have that third g-type test.

I think we all pretty much agreed it would be a good idea for Katie to just do
the treatment for g2 or g3 when Mom last posted, but perhaps best to wait a
while if g1. The 24 week tx regimen is almost as likely to be successful with
g3 as g2. And as g3 seems to have the highest correlation with HCC, it really
would be wise to be pro-active about starting tx at the earliest age when it
is most likely to be beaten.

If g1 is *added* to the mix, I'd go back to making the decision based on the
biopsy results. If staging is 0 to 1, I think I'd opt to wait for up to two
more years to see if treatment enhancements appear in 2008 (eg: vx950). I
staging is above a solid 1, I'd go for tx now, unless there's some significant
other health issue(s) that have to be resolved first...

Cheers

/greyhackles
Cactus Jammies - 20 Jan 2007 18:36 GMT
Mom,
 From what I understand, the drug Ecstasy can speed up damage to the liver,
especially if it is used while infected with hep or there is prior liver
damage.  Just to let everyone know on here.  I lost the trace to the study
or articles mentioning that fact, I believe it is still out there.

FYI

cactus jammies
(good luck to Katie, she probably has a pretty good liver, she is young and
the liver does repair itself, although more slowly while being continually
'insulted' by things like booze or X or the hard drugs.

......................

>>Today the blood results came back and totally shocking to both Katie and
>>myself they came back as her having genotype 3A! She was originally
[quoted text clipped - 27 lines]
> P.S.: Yes, it was your attachment that caused your posts to disappear.
> Most servers will reject posts with attachments in non-binary groups.
Michael Arends - 20 Jan 2007 19:48 GMT
Smiling Wickedly,  Mom answered:
> Hello all. Back for more input. Katie has been having a battery of tests run
> to see if she is a candidate for treatment. I have got to give this doctor
[quoted text clipped - 20 lines]
>
> Mom

Hi Mom,

I was a 3a also.  Usually the treatment is shorter. 24 vs 48 weeks.
However, that being said, if she is a slow responder, don't let the
doctor have her quit. My doctor had the balls to have me do the whole 48
weeks, because at the 24 week mark I had only only started responding.

I got my SVR, and i'm working on 1 1/2 years now.

Signature

*..· ´¨¨))
    ¸.·´ .·´¨¨))
  ((¸¸.·´  .·´-:¦:-((¸¸.·´(º·.¸(¨*·.¸  ¸.·*¨)¸.·º)
                            «.·°·. Michael .·°·-:¦:-

Paul - 21 Jan 2007 12:48 GMT
On Sat, 20 Jan 2007 06:21:46 -0500, "Mom" <mom@nospamplease.net>, in
message ID <iJmdnRnMzsHMZizYnZ2dnUVZ_h2pnZ2d@adelphia.com>, in the
newsgroup alt.support.hepatitis-c wrote:

>Hello all. Back for more input. Katie has been having a battery of tests run
>to see if she is a candidate for treatment. I have got to give this doctor
[quoted text clipped - 22 lines]
>
>--------------------------------------------------------------------------------

Looks like it's all been said really Mom.  Definitely re-test to
confirm genotype though.
If geno 3, maybe could get away with biopsy if treating in the near
future due to the much higher chance of success.  However, if tx
doesn't work, you would be left with no baseline to assess the speed
at which the liver damage is progressing (although this can vary
anyway so may not be critical).
I hope it's a geno 3.
I have heard things about geno 3 being a bit harder to treat than geno
2 and there were rumblings in the UK at one point of making geno 3 a
36 weeker.  I don't know what was decided but I haven't heard of it
happening yet.  Maybe it was deemed unnecessary.
 
Sign In
Join
My Latest Posts
My Monitored Threads
My Blog
My Photo Gallery
My Profile
My Homepage

Start New Thread
Enable EMail Alerts
Rate this Thread



©2009 Advenet LLC   Privacy Policy - Terms of Use
This website includes both content owned or controlled by Advenet as well as content owned or controlled by third parties.