curried rats with brown rice

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kjoh - 10 Dec 2006 00:32 GMT

Hey don't laugh this is real science. I have been looking through the
conventional and alternative literature for information about (safe?)
foods and herbs that stimulate bile production. Bile is synthesized in
the liver. It dissolves fat. Curcumin is the yellow stuff in curry
powder (turmeric). It is either coincidental or cosmic that they are the
same color :-)

Here are blurbs from three articles in pubmed.gov. I searched bile +
turmeric. As herbals go, this one is relatively well studied. Ping
Thomas: a while back you posted a source for safety profiles of common
herbal remedies. Do you remember where it was? I would like to look at
it again. Tia.

Best,
Koko

Digestive stimulant action of three Indian spice mixes in experimental
rats..."...the bile volume as well as the bile acid secretion were almost
doubled in spice mix III treatment." 2002

Alternative treatment of gallbladder disease: "...Herbal medicine such as
turmeric etc. may reduce gallbladder inflammation and relieve LIVER
CONGESTION. Elimination of offending foods, not necessarily 'fatty'
foods, is often successful and recommended by many holistic physicians."
2003

Curcumin combats against cigarette smoke and ethanol-induced lipid
alterations in rat lung and liver: "...CONCLUSION: This biochemical
picture on cotreatment with curcumin suggests that curcumin could
counteract the injurious effects of combined CS and EtOH and thus might
help to reduce the risk of hyperlipidemic disorders which develop due to
smoking and drinking." 2006

"...CONCLUSIONS: Turmeric, an approved food additive, or its component
curcumin, has shown surprisingly beneficial effects in experimental
studies of acute and chronic diseases characterized by an exaggerated
inflammatory reaction. There is ample evidence to support its clinical
use, both as a prevention and a treatment." 2003

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12577586&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=12450782&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstra
ctPlus&list_uids=16691314&query_hl=2&itool=pubmed_docsum

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=R
etrieve&dopt=abstractplus&list_uids=16387899

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Cactus Jammies - 10 Dec 2006 02:11 GMT

That business about bile production and such is what I am looking into.
Only I started on the most commonly used 'liver tonic', Milkthistle (MT).
silybum marianum (I like the sound of silybum, I guess)
The active ingredient in Milkthistle is Silymarin. Please keep in touch
about your experiences with curry/tumeric.

I wonder if there were any bites on this grant from nih.

http://grants.nih.gov/grants/guide/rfa-files/RFA-AT-05-006.html

grant application details:
3.A. Receipt, Review and Anticipated Start Dates
Letter of Intent Receipt Date: August 15, 2005
Application Receipt Date(s): September 12, 2005
Peer Review Date: October/November 2005
Council Review Date: February 3, 2006
Earliest Anticipated Start Date: April 1, 2006

Scientific knowledge to be achieved through research supported by the
special program: Efficacy and toxicity data at different doses of silymarin
against chronic hepatitis C and NASH.
a.. Objectives of this research program:
Estimation of the optimum dose of silymarin with respect to efficacy and
toxicity against one or more conditions of untreated chronic hepatitis C,
previously treated hepatitis and NASH.
a.. Types of research and experimental approaches that are being sought to
achieve the objectives:
Application for a Clinical Site should consider the standard components of
a Phase I/II clinical protocol such as background, study population, outcome
criteria, dose-ranging scheme, sample size, study site, and efficacy and
safety parameters. Because this is a study of dietary supplement in multi
sites, the following should also be considered.
cheers

cactus jammies --------------------

> Hey don't laugh this is real science. I have been looking through the
> conventional and alternative literature for information about (safe?)
[quoted text clipped - 42 lines]
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?itool=abstractplus&db=pubmed&cmd=R
etrieve&dopt=abstractplus&list_uids=16387899

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