The short answer is: it's working :-)

Otherwise, there's nothing that jumps out of your numbers as alarming.

The WBC drop will be something to keep an eye on, obviously, but so far you're
a long way from neutropenia. The Basophil/Monophils/Eosinophil numbers are
rarely interesting beyond the academic level. On treatment you can expect to
see all kinds of weird counts - and weird cells in both the WBC group (and RBC
group, for that matter) in differential analysis (just wait until you see
"Bizarre RBCs" on your differential ;-) The cells you're really interested in
are the Neutrophils; you should have an ANC (Absolute Neutrophil Count)
included in your tests.

And you're doing better in the RBC & HGB department than I did at the end of
four weeks, so even though you're feeling a lack of stamina now, hopefully you
won't experience deep anemia and have to go on the Procrit/Epogen.

The total Bilirubin is a bit high, but I had a similar spike early in
treatment, and another a few months in, but by the 6 month point it started
the slow fall back down and was well within the normal range at the end of the
48 weeks.

The ALT/AST numbers would be more interesting if the pre-tx numbers were
available. ALT/AST numbers on therapy seems to be quite "personalized" - some
folks have them leap up, some plummet down, some wander around the middle.
Mine happened to plummet, but they were almost twice yours to begin with.

Your platelet count is the one thing I think that stands out, but again one
would need to know your pre-tx number to characterize the current value. If
you were well within the normal range pre-tx (say up around 250), then that's
a fairly steep drop in four weeks. Otoh, it isn't uncommon for heppers to
sport low platelet counts before starting therapy, particularly if there is
significant liver damage present, so if you were at the low end of "normal" to
begin with the drop isn't that significant. The threshold for concern while on
therapy is down in the 50K/ml range. One thing to consider is taking Advil
(Ibuprophen) or Aspirin will negatively affect platelets, so if you're using
either of those you might consider switching to Tylenol.

So....Dropping your VL from somewhere around 3 million down to 13K is a 2 to 3
log drop, in a mere four weeks. That's a really good start! Keep up the good
work!

Cheers

/greyhackles