Medical Forum / Diseases and Disorders / Hepatitis / April 2006
NEWS: Spontaneous HCV Clearance More Common Than Previously Thought
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Thomas Wagner - 20 Apr 2006 23:37 GMT Spontaneous HCV Clearance More Common Than Previously Thought
NEW YORK (Reuters Health) Apr 19 - Spontaneous clearance of hepatitis C virus (HCV) after chronic infection is thought to be a rare event, but new research suggests that clearance rates as high as 8% may occur.
Roughly 15% to 30% of people who become infected with HCV will clear the virus during the acute phase. Until recently, it was believed that the remaining patients with chronic infection seldom, if ever, clear the virus.
In a Japanese study reported in 2003, an HCV clearance rate of 3.7% was described in patients with chronic infection. The present findings, which appear in Clinical Infectious Diseases for April 1, suggest that the rate may be higher still.
The study involved 139 Alaskan natives who had tested positive for HCV RNA on three separate occasions and were followed on a regular basis for a mean period of 7 years.
Eleven of the patients (8%) had at least one test with undetectable HCV RNA during follow-up. Seven of these patients were considered to have probable or possible HCV clearance, yielding an annual clearance rate of 0.74% per person year.
Follow-up testing of nine of the seronegative patients identified five that still appeared to be virus-free, the report indicates. A low HCV RNA titer predicted spontaneous nondetectability of HCV RNA.
In a related editorial, Dr. Georg M. Lauer and Dr. Arthur Y. Kim, from Harvard Medical School in Boston, point out that "more studies are needed before we can feel confident about the incidence of spontaneous viral clearance in chronic HCV infection or before we start investigating the genetic disposition of Alaska Natives and its relevance to viral control."
"Meanwhile, clinicians should stay alert to this rare outcome of HCV infection, and further investigations of this phenomenon should be strongly encouraged," the editorialists add.
Clin Infect Dis 2006;42:945-954.
http://www.medscape.com/viewarticle/530299
Thomas
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elmoemerson@webtv.net - 21 Apr 2006 00:30 GMT NEWS: Spontaneous HCV Clearance More Common Than Previously Thought Group: alt.support.hepatitis-c Date: Thu, Apr 20, 2006, 6:37pm (CDT+1) From: tomw@capecod.com (Thomas Wagner) Spontaneous HCV Clearance More Common Than Previously Thought NEW YORK (Reuters Health) Apr 19 - Spontaneous clearance of hepatitis C virus (HCV) after chronic infection is thought to be a rare event, but new research suggests that clearance rates as high as 8% may occur. Roughly 15% to 30% of people who become infected with HCV will clear the virus during the acute phase. Until recently, it was believed that the remaining patients with chronic infection seldom, if ever, clear the virus. In a Japanese study reported in 2003, an HCV clearance rate of 3.7% was described in patients with chronic infection. The present findings, which appear in Clinical Infectious Diseases for April 1, suggest that the rate may be higher still. The study involved 139 Alaskan natives who had tested positive for HCV RNA on three separate occasions and were followed on a regular basis for a mean period of 7 years. Eleven of the patients (8%) had at least one test with undetectable HCV RNA during follow-up. Seven of these patients were considered to have probable or possible HCV clearance, yielding an annual clearance rate of 0.74% per person year. Follow-up testing of nine of the seronegative patients identified five that still appeared to be virus-free, the report indicates. A low HCV RNA titer predicted spontaneous nondetectability of HCV RNA. In a related editorial, Dr. Georg M. Lauer and Dr. Arthur Y. Kim, from Harvard Medical School in Boston, point out that "more studies are needed before we can feel confident about the incidence of spontaneous viral clearance in chronic HCV infection or before we start investigating the genetic disposition of Alaska Natives and its relevance to viral control." "Meanwhile, clinicians should stay alert to this rare outcome of HCV infection, and further investigations of this phenomenon should be strongly encouraged," the editorialists add. Clin Infect Dis 2006;42:945-954. http://www.medscape.com/viewarticle/530299 Thomas
 Signature It's probably due to the whale blubber the Eskimos are so fond of eating. :-) elmo
http://community.webtv.net/elmoemerson/DocElmosHepFile
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kjoh - 21 Apr 2006 03:02 GMT It is. Eat oolichan oil and pickled herring. Seriously. :-) (Good find, Thomas!)
kj
"It's probably due to the whale blubber the Eskimos are so fond of eating." :-) elmo
Russ - 22 Apr 2006 14:26 GMT f.cker, you took the words out of my mouth!!!!! ;)
I'll bet it's the stinky fish heads they eat... you know, bury a bunch of fish heads till they are nice and "soft", yum, yum..... Call me around dinner time I'll tell ya some more tasty recipes..... LOL.....
 Signature Russ
Visit Alaska @ http://www.tannersacre.com
NEWS: Spontaneous HCV Clearance More Common Than Previously Thought
Group: alt.support.hepatitis-c Date: Thu, Apr 20, 2006, 6:37pm (CDT+1) From: tomw@capecod.com (Thomas Wagner) Spontaneous HCV Clearance More Common Than Previously Thought NEW YORK (Reuters Health) Apr 19 - Spontaneous clearance of hepatitis C virus (HCV) after chronic infection is thought to be a rare event, but new research suggests that clearance rates as high as 8% may occur. Roughly 15% to 30% of people who become infected with HCV will clear the virus during the acute phase. Until recently, it was believed that the remaining patients with chronic infection seldom, if ever, clear the virus. In a Japanese study reported in 2003, an HCV clearance rate of 3.7% was described in patients with chronic infection. The present findings, which appear in Clinical Infectious Diseases for April 1, suggest that the rate may be higher still. The study involved 139 Alaskan natives who had tested positive for HCV RNA on three separate occasions and were followed on a regular basis for a mean period of 7 years. Eleven of the patients (8%) had at least one test with undetectable HCV RNA during follow-up. Seven of these patients were considered to have probable or possible HCV clearance, yielding an annual clearance rate of 0.74% per person year. Follow-up testing of nine of the seronegative patients identified five that still appeared to be virus-free, the report indicates. A low HCV RNA titer predicted spontaneous nondetectability of HCV RNA. In a related editorial, Dr. Georg M. Lauer and Dr. Arthur Y. Kim, from Harvard Medical School in Boston, point out that "more studies are needed before we can feel confident about the incidence of spontaneous viral clearance in chronic HCV infection or before we start investigating the genetic disposition of Alaska Natives and its relevance to viral control." "Meanwhile, clinicians should stay alert to this rare outcome of HCV infection, and further investigations of this phenomenon should be strongly encouraged," the editorialists add. Clin Infect Dis 2006;42:945-954. http://www.medscape.com/viewarticle/530299 Thomas
 Signature It's probably due to the whale blubber the Eskimos are so fond of eating. :-) elmo
http://community.webtv.net/elmoemerson/DocElmosHepFile
http://community.webtv.net/elmoemerson/TheFamilyAlbum
elmoemerson@webtv.net - 24 Apr 2006 04:49 GMT Nothing like greasy farts just before dinner unless it's greasy farts after dinner. (sounds really romantic, don't it Dort.......aahahahhahahahaha) sh.t, Russ!! You're going to have to get down here for some real Ozarks hospitality......fantastic bbq and jammin' blues music. I got me a real smokin' machine and there's plenty of good music. Don't forget to bring 'Suzie Q', I aint seen her since I sent her to you UPS. :-) A friend of mine is 'procuring' me a gallon of the real McCoy Arkansas moonshine next week. With a little luck, I'll go blind from it. :-0 elmo ///////////// f.cker, you took the words out of my mouth!!!!! ;) I'll bet it's the stinky fish heads they eat... you know, bury a bunch of fish heads till they are nice and "soft", yum, yum..... Call me around dinner time I'll tell ya some more tasty recipes..... LOL.....
 Signature Russ Visit Alaska @ http://www.tannersacre.com <elmoemerson@webtv.net> wrote in message news:20809-44481990-358@storefull-3251.bay.webtv.net... NEWS: Spontaneous HCV Clearance More Common Than Previously Thought Group: alt.support.hepatitis-c Date: Thu, Apr 20, 2006, 6:37pm (CDT+1) From: tomw@capecod.com (Thomas Wagner) Spontaneous HCV Clearance More Common Than Previously Thought NEW YORK (Reuters Health) Apr 19 - Spontaneous clearance of hepatitis C virus (HCV) after chronic infection is thought to be a rare event, but new research suggests that clearance rates as high as 8% may occur. Roughly 15% to 30% of people who become infected with HCV will clear the virus during the acute phase. Until recently, it was believed that the remaining patients with chronic infection seldom, if ever, clear the virus. In a Japanese study reported in 2003, an HCV clearance rate of 3.7% was described in patients with chronic infection. The present findings, which appear in Clinical Infectious Diseases for April 1, suggest that the rate may be higher still. The study involved 139 Alaskan natives who had tested positive for HCV RNA on three separate occasions and were followed on a regular basis for a mean period of 7 years. Eleven of the patients (8%) had at least one test with undetectable HCV RNA during follow-up. Seven of these patients were considered to have probable or possible HCV clearance, yielding an annual clearance rate of 0.74% per person year. Follow-up testing of nine of the seronegative patients identified five that still appeared to be virus-free, the report indicates. A low HCV RNA titer predicted spontaneous nondetectability of HCV RNA. In a related editorial, Dr. Georg M. Lauer and Dr. Arthur Y. Kim, from Harvard Medical School in Boston, point out that "more studies are needed before we can feel confident about the incidence of spontaneous viral clearance in chronic HCV infection or before we start investigating the genetic disposition of Alaska Natives and its relevance to viral control." "Meanwhile, clinicians should stay alert to this rare outcome of HCV infection, and further investigations of this phenomenon should be strongly encouraged," the editorialists add. Clin Infect Dis 2006;42:945-954. http://www.medscape.com/viewarticle/530299 Thomas -- It's probably due to the whale blubber the Eskimos are so fond of eating. :-) elmo http://community.webtv.net/elmoemerson/DocElmosHepFile http://community.webtv.net/elmoemerson/TheFamilyAlbum
http://community.webtv.net/elmoemerson/DocElmosHepFile
http://community.webtv.net/elmoemerson/TheFamilyAlbum
Russ Tanner - 25 Apr 2006 04:33 GMT ah the les paul,,, I don't play it much.. I'm way into the banjo, hot licks man!!! Fingers smoking! I love it.....
Yea love those BBQ,s. Your high on my visit list buddy.. Cya next winter!
 Signature Russ
http://www.tannersacre.com
> Nothing like greasy farts just before dinner unless it's greasy farts > after dinner. (sounds really romantic, don't it [quoted text clipped - 11 lines] > of fish heads till they are nice and "soft", yum, yum..... Call me > around dinner time I'll tell ya some more tasty recipes..... LOL..... elmoemerson@webtv.net - 25 Apr 2006 13:20 GMT I'll keep the smoker warmed up for ya, Russ! elmo //////////// ah the les paul,,, I don't play it much.. I'm way into the banjo, hot licks man!!! Fingers smoking! I love it..... Yea love those BBQ,s. Your high on my visit list buddy.. Cya next winter!
 Signature Russ http://www.tannersacre.com <elmoemerson@webtv.net> wrote in message news:6366-444C4AE5-849@storefull-3252.bay.webtv.net... Nothing like greasy farts just before dinner unless it's greasy farts after dinner. (sounds really romantic, don't it Dort.......aahahahhahahahaha) sh.t, Russ!! You're going to have to get down here for some real Ozarks hospitality......fantastic bbq and jammin' blues music. I got me a real smokin' machine and there's plenty of good music. Don't forget to bring 'Suzie Q', I aint seen her since I sent her to you UPS. :-) A friend of mine is 'procuring' me a gallon of the real McCoy Arkansas moonshine next week. With a little luck, I'll go blind from it. :-0 elmo ///////////// f.cker, you took the words out of my mouth!!!!! ;) I'll bet it's the stinky fish heads they eat... you know, bury a bunch of fish heads till they are nice and "soft", yum, yum..... Call me around dinner time I'll tell ya some more tasty recipes..... LOL..... -- Russ Visit Alaska @ http://www.tannersacre.com <elmoemerson@webtv.net> wrote in message news:20809-44481990-358@storefull-3251.bay.webtv.net... NEWS: Spontaneous HCV Clearance More Common Than Previously Thought Group: alt.support.hepatitis-c Date: Thu, Apr 20, 2006, 6:37pm (CDT+1) From: tomw@capecod.com (Thomas Wagner) Spontaneous HCV Clearance More Common Than Previously Thought NEW YORK (Reuters Health) Apr 19 - Spontaneous clearance of hepatitis C virus (HCV) after chronic infection is thought to be a rare event, but new research suggests that clearance rates as high as 8% may occur. Roughly 15% to 30% of people who become infected with HCV will clear the virus during the acute phase. Until recently, it was believed that the remaining patients with chronic infection seldom, if ever, clear the virus. In a Japanese study reported in 2003, an HCV clearance rate of 3.7% was described in patients with chronic infection. The present findings, which appear in Clinical Infectious Diseases for April 1, suggest that the rate may be higher still. The study involved 139 Alaskan natives who had tested positive for HCV RNA on three separate occasions and were followed on a regular basis for a mean period of 7 years. Eleven of the patients (8%) had at least one test with undetectable HCV RNA during follow-up. Seven of these patients were considered to have probable or possible HCV clearance, yielding an annual clearance rate of 0.74% per person year. Follow-up testing of nine of the seronegative patients identified five that still appeared to be virus-free, the report indicates. A low HCV RNA titer predicted spontaneous nondetectability of HCV RNA. In a related editorial, Dr. Georg M. Lauer and Dr. Arthur Y. Kim, from Harvard Medical School in Boston, point out that "more studies are needed before we can feel confident about the incidence of spontaneous viral clearance in chronic HCV infection or before we start investigating the genetic disposition of Alaska Natives and its relevance to viral control." "Meanwhile, clinicians should stay alert to this rare outcome of HCV infection, and further investigations of this phenomenon should be strongly encouraged," the editorialists add. Clin Infect Dis 2006;42:945-954. http://www.medscape.com/viewarticle/530299 Thomas -- It's probably due to the whale blubber the Eskimos are so fond of eating. :-) elmo
http://community.webtv.net/elmoemerson/DocElmosHepFile
http://community.webtv.net/elmoemerson/TheFamilyAlbum
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