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Medical Forum / Diseases and Disorders / Hepatitis / January 2006Blood test results
Hey, Aside from my VL which I reported earlier I also have some out of range results that I'd like to share. Normal range in parens: WBC 2.2 (4.0 - 10.5) RBC 3.53 (4.10 - 5.60) Hemoglobin 10.6 (12.5 - 17.0) Hematocrit 31.0 (36.0 - 50.0) RDW 16.8 (11.7 - 15.0) Lymphs 48 (14 - 46) Neutrophils .9 (1.8 - 7.8) Can anyone comment upon these? Doc didn't advise me to do anything differently but I'll call this week to discuss anyway. Thanks. BTW: Happy New Year! > Hey, > Aside from my VL which I reported earlier I also have some out of range [quoted text clipped - 11 lines] > Thanks. > BTW: Happy New Year! Hi Stretch, I don't remember enough of Treatment Pharmacology 101 to give you any good info on your results, but I'm sure you'll get lots of good info from the others. Happy New Year to you too, dragonslayer! Waterspider >Hey, > [quoted text clipped - 17 lines] > >BTW: Happy New Year! You may have mentioned it elsewhere, but what week are you in, and what's your genotype? The whites, reds and hemoglobin/hematocrit are ok, low but not alarming. I'd only be concerned about these if you are early in therapy. The high RDW is your body trying to make up for low Red Blood Cell counts by making *larger* red cells, so no real worries here. It's expected, I had the same thing happen, and if anything, lower RDW on top of depressed RBCs would be the thing to worry about. The Neutrophil count appears to be Absolute Neutrophils, and yours are pretty darned low. Your doc should be keeping a really close eye on this particular metric as it's not far off from when dose reduction is recommended. Otoh, the Lymphs score appears to be %Lymphocytes, not Absolute Lymphocyte count. %Lymphs shows what percentage of total WBCs are due to Lymphocytes, not an actual count per volume. And because total WBC is mostly Neuts and Lymphs in a roughly 2:1 ratio, respectively, when your Neutrophils go to hell the Lymphs make up a larger proportion of the total WBC count. In your case, given the drop in Neuts, 48% Lymphs is easy to fathom, so I wouldn't be concerned about the Lymphs. The worries - if there are any - are in the Neuts. Has your doc suggested using growth factors (eg: Neupogen) to boost your Neutrophils? If not, I think it'd be prudent for you to bring the topic up for discussion... Cheers - and hang in there! /greyhackles >>Hey, >> [quoted text clipped - 50 lines] > > /greyhackles Week 9 and 1b. Thanks for your detailed response. I really appreciate it . Re: Blood test results Group: alt.support.hepatitis-c Date: Sun, Jan 1, 2006, 6:21pm (CST+1) From: lonepawn@mail.com (Stretch) greyhackles wrote: Hey, Aside from my VL which I reported earlier I also have some out of range results that I'd like to share. Normal range in parens: WBC 2.2 (4.0 - 10.5) RBC 3.53 (4.10 - 5.60) Hemoglobin 10.6 (12.5 - 17.0) Hematocrit 31.0 (36.0 - 50.0) RDW 16.8 (11.7 - 15.0) Lymphs 48 (14 - 46) Neutrophils .9 (1.8 - 7.8) Can anyone comment upon these? Doc didn't advise me to do anything differently but I'll call this week to discuss anyway. Thanks. BTW: Happy New Year! You may have mentioned it elsewhere, but what week are you in, and what's your genotype? The whites, reds and hemoglobin/hematocrit are ok, low but not alarming. I'd only be concerned about these if you are early in therapy. The high RDW is your body trying to make up for low Red Blood Cell counts by making *larger* red cells, so no real worries here. It's expected, I had the same thing happen, and if anything, lower RDW on top of depressed RBCs would be the thing to worry about. The Neutrophil count appears to be Absolute Neutrophils, and yours are pretty darned low. Your doc should be keeping a really close eye on this particular metric as it's not far off from when dose reduction is recommended. Otoh, the Lymphs score appears to be %Lymphocytes, not Absolute Lymphocyte count. %Lymphs shows what percentage of total WBCs are due to Lymphocytes, not an actual count per volume. And because total WBC is mostly Neuts and Lymphs in a roughly 2:1 ratio, respectively, when your Neutrophils go to hell the Lymphs make up a larger proportion of the total WBC count. In your case, given the drop in Neuts, 48% Lymphs is easy to fathom, so I wouldn't be concerned about the Lymphs. The worries - if there are any - are in the Neuts. Has your doc suggested using growth factors (eg: Neupogen) to boost your Neutrophils? If not, I think it'd be prudent for you to bring the topic up for discussion... Cheers - and hang in there! /greyhackles Week 9 and 1b. Thanks for your detailed response. I really appreciate it ///////////// Yep, Grey's response was right on target. It IS time you discuss Neupogen with your doc in lieu of any thoughts of dose reduction. elmo http://community.webtv.net/elmoemerson/DocElmosHepFile http://community.webtv.net/elmoemerson/TheFamilyAlbum Hi Stretch, My Doc put me on Neupogen at week 28 when my WBC's dropped to 2.4 and my neutrophils were at 0.8. It didn't make me feel fabulous, but helped a bit. My RBC at that time was a normal 4.3 and a few weeks ago at roughly shot #42 my RBC had dropped to 3.8. No Procrit (yet). Hemoglobin a tad low at 11.9. My tx will extend 6 extra weeks because I took a break at week 12, so 9 shots to go. Yay. Just my numbers for comparison. Kathy Geno1b/Virgo Not that I believe in any of that stuff (NTIBIAOTS) > Hemoglobin 10.6 (12.5 - 17.0) about where I was at, enough to make me huff and puff, but I could walk around the block ok. I couldn't do anything strenuous though. > Neutrophils .9 (1.8 - 7.8) I was down to .7 around week 20 and the doc ordered a follow up CBC a week later, said if the Neutrophils dropped below .7 to cut my Pegasys 1/2, but the came up a point and later to about 1.1 and leveled out for the rest of the treatment. Russ > Hey, > [quoted text clipped - 17 lines] > > BTW: Happy New Year! |
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