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Medical Forum / Diseases and Disorders / Hepatitis / December 2005Infergen costs
A little over a week ago I was advised to discontinue treatment because my damn virus was still replicating after 29 weeks of 15 mcg of Infergen and 1200 mg. I have decent insurance, 10 six packs of Infergen, and 3 jars of Riba 84s. If anyone is having financial difficulty paying for this type of tx please email me directly by adding dog to my username, or using your reader features. Love Life, Peace and happy holidays to all. Steve >A little over a week ago I was advised to discontinue treatment because > my damn virus was still replicating after 29 weeks of 15 mcg of > Infergen and 1200 mg. Sorry to hear this, Steve. Merry f.cking Christmas, eh? It's hard to dig anything positive out of this disappointment (that may be a bit of an understatement), but remember that tx, successful or not, gives your liver a real holiday from hcv. Btw, your description of tx seems a bit chopped off (just like the tx itself, I suppose), but were you taking peg-ifn with the Infergen or just riba? Waterspider Just Infergen & Riba - I can't imagine doing Peg at the same time. But I may be finding out in round 3. Yeah my enzymes were normal during tx so that is a good thing. I think I'll try to find a more agressive BCLD for the next round. I am G1a & F3 with high VL so it is getting serious and I want be rid of HCV pretty badly. I can't take a year off work or anything like that - all that lying around feeling like sh.t would drive me totally f.cking insane anyway. Wouldn't that be justice to get my SVR and be so crazy that I didn't even know it. Kill HCV and a happy holiday, Steve > Just Infergen & Riba - I can't imagine doing Peg at the same time. But > I may be finding out in round 3. Round three? Sorry, I didn't realize this was your second dance with the dragon. > Yeah my enzymes were normal during tx so that is a good thing. > I think I'll try to find a more agressive BCLD for the next round. I am > G1a & F3 with high VL so it is getting serious and I want be rid of HCV > pretty badly. Yup, sounds like the big guns are needed in your case, bring on the peg, bring on the peg, bring on the peg... Don't worry, Elmo's a pretty good coach about that particular program. I can't take a year off work or anything like that - all > that lying around feeling like sh.t would drive me totally f.cking > insane anyway. Wouldn't that be justice to get my SVR and be so crazy > that I didn't even know it. LOL! Good luck, Steve. Waterspider Now I'm confused (well, not just now OK) - My BCLD told me that with G1 & F3, and my previous non response to IFN alpha 2 a/Riba, my chances of SVR were much higher with Infergen/Riba than with peg-ifn/Riba tx. You gotta trust somebody sometimes for something. Is he an idiot or just playing it safe? Peace & Happiness, Steve Hi Steve. I have been under the impression that current retreatment for relapsers/nonresponders was daily infergen, but I can't find a quick reference. There may not be a clear answer to your question. Statistical probablilites for SVR are getting murkier by the day because there are so many studies with so many permutations. I did find the bit of info pasted below (from a good website called clinicaloptions.com/requires free registration). It's extracted from an outline of recent study results. Also, this is a link to research article about retreatment that involves something called ‘daily high-dose induction therapy' with interferon. Yuck. Anyway, I hope you can piece together part of your answer from this. kj http://hivandhepatitis.com/hep_c/news/2005/ad/091905_c.html From clinicaloptions.com: Some HCV-Infected Interferon Nonresponders/ Relapsers Achieve Sustained Virologic Response Following 48-Week Retreatment With Peginterferon Alfa-2b Plus Ribavirin Summary of Key Conclusions: ~20% of HCV-infected patients who failed prior treatment with standard interferon with or without ribavirin achieved sustained virologic response (SVR) following 48-week retreatment with peginterferon alfa-2b plus ribavirin ***33% of previous relapsers achieved SVR ***14% of nonresponders achieved SVR ***12% of difficult-to-treat HCV genotype 1 nonresponders achieved SVR Background Treatment options not well defined for HCV-infected patients who relapse or do not respond to prior treatment with interferon with or without ribavirin ***No clear consensus guidelines ***No FDA-approved therapies >>Now I'm confused (well, not just now OK) - My BCLD told me that with G1 & F3, and my previous non response to IFN alpha 2 a/Riba, my chances of SVR were much higher with Infergen/Riba than with peg-ifn/Riba tx. You gotta trust somebody sometimes for something. Is he an idiot or just playing it safe? Peace & Happiness, Steve kj wrote: >From clinicaloptions.com: Some HCV-Infected Interferon Nonresponders/ Relapsers Achieve Sustained Virologic Response Following 48-Week Retreatment With Peginterferon Alfa-2b Plus Ribavirin Thanks kj - Another medical research site to add to my ever expanding list. I really am beginning to think that the medical people don't have a clue. They just seem to agents of the drug companies. Next time I try tx, I will be stronger and much better informed. This 2nd tx I entered reluctantly, (never missed a dose though) therefore not as well prepared as I could have been. > A little over a week ago I was advised to discontinue treatment because > my damn virus was still replicating after 29 weeks of 15 mcg of [quoted text clipped - 10 lines] > > Steve email sent about meds. Happy Holidays, Jim > > A little over a week ago I was advised to discontinue treatment because > > my damn virus was still replicating after 29 weeks of 15 mcg of [quoted text clipped - 10 lines] > > > > Steve Thank you Steve. This really helps and is very greatly appreciated. Santa came twice this year :-) It came today. The best of luck in when you decide to try treatment again. Thanks again, Jim > A little over a week ago I was advised to discontinue treatment because > my damn virus was still replicating after 29 weeks of 15 mcg of > Infergen and 1200 mg. I have decent insurance, 10 six packs of Infergen, and 3 jars of Riba > 84s. If anyone is having financial difficulty paying for this type of tx > please email me directly by adding dog to my username, or using your > reader features. > Love Life, Peace and happy holidays to all. Steve, You must be a really caring and nice person.Wishing you the best and happy holidays as well. john |
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