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Medical Forum / Diseases and Disorders / Hepatitis / October 2005

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Good news: ETR

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ghibelno - 06 Oct 2005 14:24 GMT
Hi all,
    I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
Yes!

LFTs do look great to me too:
   
    ALT:    24
    AST:    22

Thyroid levels are in the range, so it looks ok, doesn't it?

Iron is very low (38) and ferritin a little bit over the range: 584,
what do you think about these ones?
Did you experience a high level of ferritin and a so-low iron level,
during treatment?

I feel good today, happy could join greyhackles and CJ in reaching this
target. Hope that this good news will give some relief to all the people
who are now starting treatment, as they gave it to me when I was.

Now, let's relax and enjoy this moment, next checkpoint will be in mid
December, three months after end of treatment.

Have a nice day you all.

:)

Cheers,
jeeb.
elmoemerson@webtv.net - 06 Oct 2005 14:35 GMT
Don't remember what my ferratin and iron levels were at end of tx, so I
can't comment about that.  But your numbers look pretty darn good, Jeeb.
Congrads on making it thru and all the best towards getting your SVR!
elmo

http://community.webtv.net/elmoemerson/DocElmosHepFile

http://community.webtv.net/elmoemerson/TheFamilyAlbum
ghibelno - 06 Oct 2005 14:49 GMT
elmoemerson@webtv.net ha scritto:
> Don't remember what my ferratin and iron levels were at end of tx, so I
> can't comment about that.  But your numbers look pretty darn good, Jeeb.

Thanks Elmo! :)

> Congrads on making it thru and all the best towards getting your SVR!
> elmo

You helped a lot, as well as others, here.

I don't know, I feel the need to celebrate this someway, don't know how
but I'll manage to find something...

Cheers,
jeeb.
greyhackles - 06 Oct 2005 23:20 GMT
>elmoemerson@webtv.net ha scritto:
>> Don't remember what my ferratin and iron levels were at end of tx, so I
[quoted text clipped - 9 lines]
>I don't know, I feel the need to celebrate this someway, don't know how
>but I'll manage to find something...

lol - I have the same sense of need. I'm thinking a half-glass of some nice
red wine with dinner tonite, for the first dram in 18 months...

Cheers

/greyhackles
JV - 06 Oct 2005 15:47 GMT
Well glad you made it Geeb your labs look good. Though your iron levels
are off. I have read ferritin levels can be deceiving in Hep C and not
tell the whole story. Mine was over range in Ferritin before tx, but now
it is 70 which is on the low side with bottom cut off being 10.  Did
they do a Total Binding Iron test. If TBI is high it means your binding
serum is looking for iron and your low. Actually your iron doesn't make
sense yet. Give it some time but keep a close eye on it.
I don't see you Thyroid labs here? I would suggest that you get tested
for thyroid antibodies, this is a good marker for judgment later if
needed. Some lose all their antibodies against the thyroid after tx,
some get more or less after tx.  
Enjoy the fact that tx is behind you :›)....
                                        Juanita  

¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬¬
Hi all
                I just got 48th week
(End of treatment) lab results: UNDETECTABLE! :)
Yes!
LFTs do look great to me too:
                ALT:   24
        AST:   22
Thyroid levels are in the range, so it looks ok, doesn't it?
Iron is very low (38) and ferritin a little bit over the range: 584,
what do you think about these ones?
Did you experience a high level of ferritin and a so-low iron level,
during treatment?
I feel good today, happy could join greyhackles and CJ in reaching this
target. Hope that this good news will give some relief to all the people
who are now starting treatment, as they gave it to me when I was.
Now, let's relax and enjoy this moment, next checkpoint will be in mid
December, three months after end of treatment.
Have a nice day you all.
:)
Cheers,
jeeb.
ghibelno - 06 Oct 2005 16:21 GMT
JV ha scritto:
> I have read ferritin levels can be deceiving in Hep C and not
> tell the whole story.

Yes, my doctor keeps telling me it's normal that ferritin is not being
in the range during treatment.

> Did
> they do a Total Binding Iron test. If TBI is high it means your binding
> serum is looking for iron and your low. Actually your iron doesn't make
> sense yet. Give it some time but keep a close eye on it.

I don't think TBI was scheduled. Thanks for the advice, I will keep an
eye on it.

> I don't see you Thyroid labs here? I would suggest that you get tested
> for thyroid antibodies,

FT3:     3.2     (used range: 2.3-4.2)
FT4:    1.24    (used range: 0.8-1.7)
TSH:    1.47    (used range: 0.1-4.0)

What do you think about them?

> Enjoy the fact that tx is behind you :›)....
>                                          Juanita  

Thanks,
jeeb.
JV - 06 Oct 2005 17:26 GMT
Your labs on thyroid look really, really good. Their all in a good
balance for finishing up tx. . Mid range or better. TSH looks real good
as well. Your Free T4 is only 44 digits above bottom cut off so watch it
with the iron. Getting back to the iron. Iron Total, Transferrin, Total
iron binding, Iron % sa, and Ferritin will provide more information next
time around.. Have you had your B12 checked? Its vital to life an if you
have low iron which it looks like, the possibility of low B12 is more
likely as well.  
On the antibodies I now have both types
Thyroglobulin ab    20      range  0.0– 25.0 TPO ab      1.0
range        0.0–2.0
Mine are below limit, no telling what they were before thyroid meds or
on tx. Still waiting for those records. I didn't have them before tx got
labs to prove it having them is a attack on the thyroid whether their in
10, 100, 1000, 10000s.
Well your off to a very good start now, glad you made it. Tizz time to
have some fun. Energy returning is such a nice buzzzzzz.
                                        Juanita    
greyhackles - 06 Oct 2005 23:17 GMT
>Hi all,
>    I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
>Cheers,
>jeeb.

Your numbers look beautiful, jeeb!

Along with the LFTs, and a TSH of 1.36 (comfortably normal) I had a similar
serum ferritin reading in Week 48: it was 656 ng/ml, about double the
high-normal point of 322 ng/ml for my lab.

But context is everything: my serum ferritin levels went from pre-tx of 340 to
1190(!) a month into tx, but have been slowly coming down since, so 600+ is
actually a good indicator for me. If you were following the same track, I'd
take 584 as a sign of recovery from the sx...

Good stuff! Congrats!

/greyhackles
mags - 07 Oct 2005 00:49 GMT
Way to go jeeb.  don't leave the site as us newbies need experienced people
like you!

Mags
> Hi all,
> I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
> Cheers,
> jeeb.
pajaritaflora - 07 Oct 2005 04:30 GMT
> Hi all,
>     I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
> Cheers,
> jeeb.

Congratulations Jeeb,
I'm wicked happy for you. :)Fingers crossed for an SVR.
MaryAnn
Russ - 07 Oct 2005 06:46 GMT
Right on man, it's great to finish isn't it? The best wishes for your post
tx PCR!!!!!

Signature

Russ

Visit Alaska @ http://www.tannersacre.com

> Hi all,
> I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
> Cheers,
> jeeb.
Paul - 07 Oct 2005 09:11 GMT
On Thu, 06 Oct 2005 15:24:45 +0200, ghibelno
<ghibelno@_NOSPAMMEPLEASE_yahoo.it>, in message ID
<di38j3$5g8$1@domitilla.aioe.org>, in the newsgroup
alt.support.hepatitis-c wrote:

>Hi all,
>    I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
>Cheers,
>jeeb.

Wow !! Loads of good news around here lately  :-)

Signature

Paul

Use the reply by email facility in your
newsreader to send email

Ikiru - 07 Oct 2005 22:22 GMT
>Hi all,
>    I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 4 lines]
>    ALT:    24
>    AST:    22

Jeeb, I don't really know about those ferratin and iron levels because
I didn't get those at the end of tx.  But I'd like to congratulate you
on finishing tx and with undetectable status and nice LFTs.  You
deserve some kind of celebration that's fore sure.

Don
ghibelno - 08 Oct 2005 10:42 GMT
> Hi all,
>     I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 12 lines]
> Cheers,
> jeeb.

Well, thanks all for your comments, they helped me a lot, as usual :)

I'm just coming from my family doctor's office, now, as he said he
wanted to check labs et cetera.
He was actually satisfied by the response during treatment.
He said liver parameters looks fine, and thyroid too.
He is still concerned about the anemia I showed during and at the end
of treatment, anyway.
In his opinion an iron level value of 38 is a little bit to low.
He would like me to start taking an iron supplement, make labs to check
for blood in bowels and have another lab test to check LFT, iron and
ferritin in a month.
So, I told my gastroenterologists about this and they said they agree
but about taking iron.
In their opinion, in fact, anemia (and then low iron) is due to the
fact my body was still on treatment when I gave the last blood sample
(one week after the last Interferon injection and the morning after the
last riba pills). And, more, taking iron with a high ferritin level
(which in their opinion should be related to treatment as well) is not
a good thing.
So they're going to talk one another about the whole thing on Monday
and then let me know what to do.

So that's the way it is. I still feel good and going to celebrate,
tonight or tomorrow, somehow.

Have a nice day you all.

Cheers,
jeeb.
greyhackles - 08 Oct 2005 18:09 GMT
>> Hi all,
>>     I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 43 lines]
>Cheers,
>jeeb.

Was that 38 your actual iron level, or was it your iron saturation level? If
the former, it's indeed remarkably low; if the latter, it's almost dead center
of normal range.

With all of this, what actually were your RBC and HGB levels on the same test?

I suspect our cases are more identical than not. My tests were drawn 5 days
after my last IFN shot, and with a few days of Riba to finish. My iron
saturation level (Iron over Total Iron Binding Capacity) was 38% on that test
(Iron was 132 ug/dl, TIBC was 344). Again, smack dead center of normal range.

In this case, I certainly would take your GI docs advise over your GP, and
wait for another set of test results taken at least a couple of week outs from
the end of therapy. And definitely *don't* throw iron at your anemia, which
almost certainly is a transient side effect of therapy.

So how are you feeling these days? Feeling any rise in energy levels yet?

Cheers

/greyhackles
ghibelno - 10 Oct 2005 09:24 GMT
greyhackles ha scritto:
> [...]
> Was that 38 your actual iron level, or was it your iron saturation level? If
> the former, it's indeed remarkably low;

The former. In fact it is low...
Anyway, Iron has been around 60 (lower range value) during all the
terapy. Then, I was put on a vitaminn supplement from week 40 to week
43/44 (about one month) to help WBC and RBC count grow.
My gastroenterologist doctor says that being off these vitamins for the
last weeks probably made my body consume more Iron to keep building RBC
up and that could be the reason it is remarkably lower than it used to be.

> what actually were your RBC and HGB levels on the same test?

WBC:    3.1    (ANC:    1,7 * 10^3)
RBC:    3.2
HGB:    10.1

> I suspect our cases are more identical than not. [...]
> [...] I certainly would take your GI docs advise over your GP, and
> wait for another set of test results taken at least a couple of week outs from
> the end of therapy. And definitely *don't* throw iron at your anemia, which
> almost certainly is a transient side effect of therapy.

Well, your words are the same of my gastroenterologist doctor.
She scheduled the next set of test in a couple of weeks (it will be 4
weeks after the end of treatment, then) and TIB and UIB values will be
checked, too.
More, she said that she does expect to see a lower Ferritin level and an
increase in blood cells count and hemoglobin, but she also said that
iron might still be low, just because body will be using a lot of it to
build up blood cells.

> So how are you feeling these days? Feeling any rise in energy levels yet?

Yes.
I can say I did notice the return of appetite (I actually found myself
almost salivating in front of a pasta, yesterday :) ) and that I'm not
so short of breath and weakened after a couple of floors of stairs in
the morning.

Cheers,
jeeb.
elmoemerson@webtv.net - 09 Oct 2005 15:01 GMT

Re: Good news: ETR  

Group: alt.support.hepatitis-c Date: Sat, Oct 8, 2005, 2:42am (CDT-2)
From: ghibelno@yahoo.it (ghibelno)
ghibelno wrote:
Hi all,
               I just got 48th week (End
of treatment) lab results: UNDETECTABLE! :) Yes!
LFTs do look great to me too:
                ALT:   24
        AST:   22
Thyroid levels are in the range, so it looks ok, doesn't it?
Iron is very low (38) and ferritin a little bit over the range: 584,
what do you think about these ones?
[...]
Cheers,
jeeb.
Well, thanks all for your comments, they helped me a lot, as usual :)
I'm just coming from my family doctor's office, now, as he said he
wanted to check labs et cetera.
He was actually satisfied by the response during treatment. He said
liver parameters looks fine, and thyroid too. He is still concerned
about the anemia I showed during and at the end of treatment, anyway.
In his opinion an iron level value of 38 is a little bit to low. He
would like me to start taking an iron supplement, make labs to check for
blood in bowels and have another lab test to check LFT, iron and
ferritin in a month.
So, I told my gastroenterologists about this and they said they agree
but about taking iron.
In their opinion, in fact, anemia (and then low iron) is due to the fact
my body was still on treatment when I gave the last blood sample (one
week after the last Interferon injection and the morning after the last
riba pills). And, more, taking iron with a high ferritin level (which in
their opinion should be related to treatment as well) is not a good
thing.
So they're going to talk one another about the whole thing on Monday and
then let me know what to do.
So that's the way it is. I still feel good and going to celebrate,
tonight or tomorrow, somehow.
Have a nice day you all.
Cheers,
jeeb.
////////////
Your GI doc has it correct.  
Elmo

http://community.webtv.net/elmoemerson/DocElmosHepFile

http://community.webtv.net/elmoemerson/TheFamilyAlbum
ghibelno - 10 Oct 2005 09:26 GMT
elmoemerson@webtv.net ha scritto:
> Your GI doc has it correct.  
> Elmo

Yes, Elmo, I do think so as well.
Now the task is to make them agree about the Iron thing.

Cheers,
jeeb.
JV - 10 Oct 2005 16:54 GMT
It would make sense to wait and see where your labs take you in a month.
My Ferritin used to be over the limit as well which has normalized now.
Give it time and recover from tx, have fun celebrating.
Juanita
elmoemerson@webtv.net - 09 Oct 2005 14:58 GMT
Looking back, my ferratin levels were high too during tx.  It was
explained to me by my NP that that was not unusual due to all the
exploding red blood cells
elmo

 

http://community.webtv.net/elmoemerson/DocElmosHepFile

http://community.webtv.net/elmoemerson/TheFamilyAlbum
Shawn - 11 Oct 2005 01:54 GMT
Congrats!!!

Signature

Shawn
(use the "reply feature on your browser to send a private reply via E-Mail.)

> Hi all,
> I just got 48th week (End of treatment) lab results: UNDETECTABLE! :)
[quoted text clipped - 25 lines]
> Cheers,
> jeeb.
 
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