Spontaneous Clearance

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anonymousone - 28 Sep 2005 20:00 GMT

Does anybody know if there are any studies about this supposedly 15-20%
spontaneous clearance?

Specifically, does this tend to happen at any particular time. Right
after infection, the first few years, or perhaps at any time?

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Thomas Wagner - 28 Sep 2005 20:11 GMT

>Does anybody know if there are any studies about this supposedly 15-20%
>spontaneous clearance?
>
>Specifically, does this tend to happen at any particular time. Right
>after infection, the first few years, or perhaps at any time?

It's within the first 6 months, while the infection is still acute. Once
the HCV has become chronic, spontaneous clearance is extremely rare.

Thomas

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Incantatrix - 28 Sep 2005 20:26 GMT

Thomas Wagner <tomw@capecod.com> <chqlj19va0qnggii5il0jpj64prhilmcv8@4ax.com> :

>>Does anybody know if there are any studies about this supposedly 15-20%
>>spontaneous clearance?
[quoted text clipped - 6 lines]
>
>Thomas

a friend of mine here in belgium is such an extremely rare case. she was infected over twenty years
ago (then diagnosed as nonA/nonB, later when tests were available dx with chronic HCV)
(and sidenote: she only stopped using dope for three years, she didn't change her lifestyle
at all, clearance happened after she started using speed again, how ironic)
i am not going to give that a try though. lol. i am infected for over twenty years as well
but i have no liver damage at all. i managed to battle the chronic fatigue i suffered with
traditional chinese medicine, with the blessing of my liver specialist. he was amazed about
the results and is now even forwarding other patients of him who suffer CFS (that often comes
with hcv) to my chinese doctor. i hope for them their results will be as beneficial as they
were for me.
regards thomas
anja

--

mhm 35x6
smeeter 37(?)
wsd40

we are all in the gutter but some of us are looking at the stars
wilde

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Thomas Wagner - 28 Sep 2005 22:22 GMT

>a friend of mine here in belgium is such an extremely rare case. she was infected over twenty years
>ago (then diagnosed as nonA/nonB, later when tests were available dx with chronic HCV)
>(and sidenote: she only stopped using dope for three years, she didn't change her lifestyle
>at all, clearance happened after she started using speed again, how ironic)

Heh... ironic indeed. I don't believe I've seen any clues to the
possible cause of those cases. There probably are too few to find a
pattern. I've heard rumors about a possible connection to pregnancy in
women (immune system + hormone boost, the virus seems to have problems
with estrogen). But I haven't seen any confirmation, and your friend's
case probably didn't involve a pregnancy (at least I'd hope not).

>i am not going to give that a try though. lol. i am infected for over twenty years as well
>but i have no liver damage at all. i managed to battle the chronic fatigue i suffered with
>traditional chinese medicine, with the blessing of my liver specialist. he was amazed about
>the results and is now even forwarding other patients of him who suffer CFS (that often comes
>with hcv) to my chinese doctor. i hope for them their results will be as beneficial as they
>were for me.

Cool. Whatever works. If you can stay damage-free for the next 4-5
years, I believe we'll see much gentler treatments becoming a reality.
With so much active research from so many different angles, something
just has to work.

Thomas

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Incantatrix - 28 Sep 2005 23:08 GMT

Thomas Wagner <tomw@capecod.com> <ut1mj1h870m5al6qak52ugemhre9kn95kc@4ax.com> :

>>a friend of mine here in belgium is such an extremely rare case. she was infected over twenty years
>>ago (then diagnosed as nonA/nonB, later when tests were available dx with chronic HCV)
[quoted text clipped - 4 lines]
>possible cause of those cases. There probably are too few to find a
>pattern.

i wonder if their blood circulates in laboratories all over the world to find one.

>I've heard rumors about a possible connection to pregnancy in
>women (immune system + hormone boost, the virus seems to have problems
>with estrogen). But I haven't seen any confirmation, and your friend's
>case probably didn't involve a pregnancy (at least I'd hope not).

she hates children and so took care to never get pregnant. she is 46 now btw, a little late
for still getting preggers, she cleared two years ago. doctors are stunned, especially because
they know about her lifestyle.
btw, she never had any liver damage either when she still was positive and she drinks a lot on top
of the speed as well.

>>i am not going to give that a try though. lol. i am infected for over twenty years as well
>>but i have no liver damage at all. i managed to battle the chronic fatigue i suffered with
[quoted text clipped - 7 lines]
>With so much active research from so many different angles, something
>just has to work.

my hepatologist doesn't find it necessary to treat when having no damage and being infected for so
long.
he prefers also i wait for better things to come. and i trust his opinion. he is a very renomated
doctor in belgium. and very open minded. he does my bloodwork monthly as well to evaluate the
influence of the traditional chinese medicine. we all know it won't clear the hep, but it did
miracles for my CFS and rheumatic pains (which are completely gone with acupuncture!) but even the
bloodtests who where out of range are stabilized now. (cholesterol, glucose, alt (which was formerly
at 28, so never much elevated anyway). my bloodpressure went from a fable 10/6 to an amazing 14/8.
so you can imagine i feel much better now. for the first time in my life i weigh over 50 kilo's
(51.7 to be precise) and that makes me feel much stronger as well.
i am going to take up yoga classes now. i already prepared a meditation room in my house. my ohm
room ;)

time for sleep, have a good night yourself too.
anja

--

mhm 35x6
smeeter 37(?)
wsd40

we are all in the gutter but some of us are looking at the stars
wilde

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Waterspider - 28 Sep 2005 21:42 GMT

> Does anybody know if there are any studies about this supposedly 15-20%
> spontaneous clearance?
>
> Specifically, does this tend to happen at any particular time. Right
> after infection, the first few years, or perhaps at any time?

About 15% of people infected with HCV will clear within six months of
exposure; their immune system destroys the virus. After the six months,
forget it.

Waterspider

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Gordo Mondragon - 28 Sep 2005 22:33 GMT

> Does anybody know if there are any studies about this supposedly 15-20%
> spontaneous clearance?
>
> Specifically, does this tend to happen at any particular time. Right
> after infection, the first few years, or perhaps at any time?

I've seen mentions that it can be up to 24 weeks after infection. The
big question right now is, how can you tell if someone is going to clear
spontaneously? Seems to be a combination of a symptomatic reaction (aka
turning yellow) and a fast reduction in viral load. The problem is that
it's a big risk - if you miss the six-month-after-infection window
you're f.cked.

The 15-20% number is just a big guess. One study found that 52% of
people who presented with symptoms cleared on their own, but none of the
people with no symptoms cleared. There is another study that showed a
much lower rate of spontaneous clearance with genotype 1 than with 3.

Except for a few weird cases, it seems that if you show symptoms and
don't clear by 12 weeks afterwards then you should treat. If you're
within two months of exposure and you're not showing any symptoms then
you need to treat.

If you're not clear by 6 months after infection it seems to be very
unlikely you'll clear on your own.

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elmoemerson@webtv.net - 29 Sep 2005 13:51 GMT

Spontaneous Clearance

Group: alt.support.hepatitis-c Date: Wed, Sep 28, 2005, 12:00pm (CDT-2)
From: tedw2@earthlink.net (anonymousone)
Does anybody know if there are any studies about this supposedly 15-20%
spontaneous clearance?
Specifically, does this tend to happen at any particular time. Right
after infection, the first few years, or perhaps at any time?
////////////
It happens within the first 6 months of infection. After that, it
almost never clears without combo tx.
Elmo

http://community.webtv.net/elmoemerson/DocElmosHepFile

http://community.webtv.net/elmoemerson/TheFamilyAlbum

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