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Medical Forum / Diseases and Disorders / Hepatitis / April 2005Hepatitis C virus infection / IRON
<<snip>> CONCLUSION: HCV infection is significantly associated with higher serum levels of ferritin and iron in the US population. <<snip>> Clin Infect Dis. 2005 Mar 15;40(6):834-41. Epub 2005 Feb 21. Related Articles, Links Association of hepatitis C virus infection with serum iron status: analysis of data from the third National Health and Nutrition Examination Survey. Shan Y, Lambrecht RW, Bonkovsky HL. Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA. Shan@uchc.edu BACKGROUND: There is growing evidence that mildly increased amounts of iron in the liver can increase hepatic injury, particularly if combined with other hepatotoxic factors, such as alcohol use, use of porphyrogenic drugs, or chronic viral hepatitis. In the present study, the association of hepatitis C virus (HCV) infection with serum measurements of iron status was assessed in the US population. METHODS: We analyzed data from a total of 14,462 participants in the Third National Health and Nutrition Examination Survey. We excluded subjects who were aged <12 years, subjects for whom measurements of serum levels of iron or ferritin or the results of liver function tests were missing, and subjects who had a serum transferrin saturation of > or =50% (to help exclude subjects with hemochromatosis). RESULTS: Mean serum levels of ferritin and iron (+/- standard error) were significantly higher among subjects with HCV infection (100+/-3 ng/mL and 229+/-17 microg/dL, respectively) than among subjects without liver disease (83+/-0.3 ng/mL and 101+/-2.1 microg/dL, respectively) (P<.0001). Serum levels of ferritin were directly and significantly correlated with serum levels of alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyl transpeptidase (r=0.25, r=0.24, and r=0.28, respectively; P<.0001), whereas platelet counts were inversely correlated with serum levels of ferritin (r=-0.12; P<.0001). CONCLUSION: HCV infection is significantly associated with higher serum levels of ferritin and iron in the US population. PMID: 15736017 [PubMed - in process] -------------------------------------------------------------------------------- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > Tom > Jesus Was A Vegetarian! No! He went fishing and he even gave other people fish to eat. You can't go twisting things round like this yaknow. Firebird >> Tom >> Jesus Was A Vegetarian! [quoted text clipped - 4 lines] > >Firebird That's ok, there's little to no consensus that serum ferritin in HCV patients has any correlation with....anything.... /greyhackles > >> Tom > >> Jesus Was A Vegetarian! [quoted text clipped - 9 lines] > > /greyhackles Oh I know that, and I argued on that topic with Tom many times in the past, but people don't understand the science and get pissed-off at me, but anybody can pick up a Bible and read how Jesus gave people fish to eat, and a lie is a lie, and God is truth. Either you accept the whole story of Jesus including the part in which he was a fisherman and gave his friends fish and bread to eat, or you reject the whole story, and anybody who twists a story that can be read and understood by anybody at all, must be one hell of a flim-flan man. Firebird >>There's little to no consensus that serum ferritin in HCV patients has any correlation with .. anything << Consensus .. ? Consensus .. ? If you are waiting for .. consensus .. FROM .. a group {medical professionals] .. WHO .. believe .. we are MISSING .. iron filings from our diet .. then .. I think you may be .. dreaming .. Even six year olds can understand when I explain it to them .. but .. others .. Real .. rocket scientists .. Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://pages.ivillage.com/ironjustice/manisaherbivore DEAD PEOPLE WALKING http://pages.ivillage.com/ironjustice/deadpeoplewalking > >>There's little to no consensus that serum ferritin in HCV patients > has any correlation with .. anything << [quoted text clipped - 15 lines] > Jesus Was A Vegetarian! > Man Is A Herbivore! Can you also explain why a herbivore would need incisors? All "herbivores" have flat grinding teeth. Man has sharp incisors. Maybe you can fool a 6 year old, but not us. Well, my ferratin levels were high and out of normal range although iron was normal. But I doubt that Jesus was a vegetarian. The buddha probably was though. In either case though, so what? "Kozure Ookami" > Is a crossposting idiot. > Stop crossposters by using this message as [quoted text clipped - 4 lines] > the sooner they'll learn. > Keep The Internet Free - of Idiots Andrew >> It takes a few seconds to excommunicate >> the idiots, and the more people that do it, >> the sooner they'll learn. >> Keep The Internet Free - of Idiots > >Andrew Great idea. You can do you part by staying off. Moron. |
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