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Medical Forum / Diseases and Disorders / Hepatitis / October 2004

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Hybrid

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Dltcynthia - 11 Oct 2004 02:52 GMT
I've had my liver bisopy and it shows no damage, my blood work came back and
when I asked what genotype was told they didn't know asked what exactly did
that mean she said it could be that the viral count is under 1000 or it could
be a  HYBRID, can anybody explain that to me! When I started my viral count was
over 2 million, 4 months later another DR who sayes I'm under 1000 or a hybrid
what am I to do? Have an app. in Nov. to recheck. What is a HYBRID???
Don - 11 Oct 2004 03:42 GMT
>I've had my liver bisopy and it shows no damage, my blood work came back and
>when I asked what genotype was told they didn't know asked what exactly did
>that mean she said it could be that the viral count is under 1000 or it could
>be a  HYBRID, can anybody explain that to me! When I started my viral count was
>over 2 million, 4 months later another DR who sayes I'm under 1000 or a hybrid
>what am I to do? Have an app. in Nov. to recheck. What is a HYBRID???

I haven't heard of any "hybrids" but I hear it is possible to have
more than one strain.  Still, the Doctor should be able to explain
better.  Which is it?  And what is a hybrid?  What did they tell you
when your viral count was over 2 million, should have had a genotype
then.  Recheck?  Maybe the labs were just botched.   I always make
sure to get my own copies.
Paul - 11 Oct 2004 07:20 GMT
On 11 Oct 2004 01:52:30 GMT, dltcynthia@aol.com (Dltcynthia), in
message ID <20041010215230.16506.00001322@mb-m27.aol.com>, in the
newsgroup alt.support.hepatitis-c wrote:

>I've had my liver bisopy and it shows no damage, my blood work came back and
>when I asked what genotype was told they didn't know asked what exactly did
>that mean she said it could be that the viral count is under 1000 or it could
>be a  HYBRID, can anybody explain that to me! When I started my viral count was
>over 2 million, 4 months later another DR who sayes I'm under 1000 or a hybrid
>what am I to do? Have an app. in Nov. to recheck. What is a HYBRID???

First of all, I'm pleased to hear that your liver is undamaged.
For reasons that I won't detail in here, I actually went and paid for
a genotype test (cost me about 110 pounds sterling) and the result was
about 12 weeks getting back to me as they kept having to retest the
sample as they called it a hybrid.  My understanding of "hybrid" is
that it is a mix of genotypes.  However, in the final analysis, they
called my genotype 2B.  It doesn't matter if you do have a hybrid, so
long as the genotype that would require the most treatment is found.
It sounds like my "hybrid" was 2B and another genotype that also only
needed 24 weeks tx.  However, they clearly stated that it was not a
geno 1 and not a geno 4.  A previous geno test had ruled out genos 5
and 6.  By process of elimination, mine was a 2 or a 3 which both
required same tx.  It's not absolutely necessary to pinpoint exact
genotype so long as the ones needing 48 weeks tx are ruled out.

As for the viral load, that can fluctuate a lot anyway.  Having said
that, 2 million to under a thousand does sound like quite a wild
fluctuation.

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Paul

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