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Medical Forum / Diseases and Disorders / Hepatitis / April 2004

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12 week response vs svr

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spokin - 28 Apr 2004 16:51 GMT
Back at my 12 week test on combo, I'd been hearing a consensus that a
detectable vL response @ 12 weeks indicated a probability of
non-response (no SVR). My gastro at that time said he thot no, that
more association was with >2 log vL reduction, and I had more than
that reduction, so he was optimistic.

Just got my 6 mo vL - still undetectable. (!!)  My 12 wk vL was NOT
undectable, but was REAL low. This would stand as (anecdotal) evidence
that the >2 log drop by 12 weeks indicates higher probability of SVR @
6 months. That's a little more optimistic than the "Got to have
undectable @ 12 weeks" thinking.

Hang in there everybody.

Mark
Paul - 28 Apr 2004 19:18 GMT
On 28 Apr 2004 08:51:53 -0700, spoking@bellsouth.net (spokin), in
message ID <cb8310a2.0404280751.1765b849@posting.google.com>, in the
newsgroup alt.support.hepatitis-c wrote:

>Just got my 6 mo vL - still undetectable. (!!)  My 12 wk vL was NOT
>undectable, but was REAL low. This would stand as (anecdotal) evidence
>that the >2 log drop by 12 weeks indicates higher probability of SVR @
>6 months. That's a little more optimistic than the "Got to have
>undectable @ 12 weeks" thinking.

Sounds good.  Undetectable today.  I also have heard that the earlier
the virus clears, the better the chance of sustaining it.  I don't
know if it's fact but it does seem logical.
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Paul

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