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Medical Forum / Diseases and Disorders / Glaucoma / June 2006

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Ben Beck - 28 May 2006 15:58 GMT
Official medicine: high pressure in the eyeball is treated with
pressure-lowering medications (eye drops).
Question: is there sufficient support from the statistics that the benifits
off this treatment overweigh the drawbacks?

In the BusinessWeek of last week (dated MAY 29,2006) there is on pages 72-79
an article (Medical Guesswork by John Carey) describing several common
medical treatments which seem to be more based on traditions and vested
interests than on scientific facts.

I cite from page 75:
"Appointed a full professor at Stanford, then recruted as chairman of the
Center for Health Policy Research & Education at Duke Unversity, Eddy proved
again and again that the emperor has no clothes. In one study, he ferreted
out decades of research evaluating treatment of high pressure in the
eyeball, a condition that can lead to glaucoma and blindness. He found about
a dozen studies that looked at outcomes with pressure-lowering medications
used on millions of people. The studies actually suggested that the
100-year-old treatment was harmful, causing more cases of blindness, not
fewer.
  Eddy submitted a paper to the Journal of the American Medical Assn.
(JAMA), whose editors sent it out to specialists for review. It was
amazing, Eddy recalls. The tom-toms sounded among all the
ophthalmologists, who marshaled a counterattack.  I felt like Salman
Rushdie.  Stanford ophthalmologist Kuldev Singh says: Dr. Eddy challenged
the community to prove that we actually had evidence. He did a service by
stimulating clinical trials, which showed that the treatment did slow the
disease in a minority of patients."

Comments?
tkopan1@yahoo.com - 19 Jun 2006 23:29 GMT
I would suggest that the author supply the statistics on thse patients
who are not helped by the drops.  There are several classes of drops,
the newest of which are the prostogladins like Xalatan, and Lumigan and
Travatan which lower pressures over 20%.

Studies show that high pressures over long periods of time will slowly
kill the retina and leave you first with tunnel vision and then total
blindness.  Studies also show that the use of eye drops and/or oral
medications have been shown to effectively lower and control the
prssures.

There are obviously cases that may require surgery to keep the
pressures under control.  My experience is that these are the exception
rather than the rule.

One needs to consult their doctor before even considering such a
measure.

--Dr. Tom
> Official medicine: high pressure in the eyeball is treated with
> pressure-lowering medications (eye drops).
[quoted text clipped - 26 lines]
>
> Comments?
Ben Beck - 20 Jun 2006 18:21 GMT
Perhaps things are more complex.
From the following 3 articles it seems that it is not clear  if the benefits
of early treatment always outweigh the harms.
http://www.ahrq.gov/clinic/uspstf05/glaucoma/glaucrs.htm
http://www.ahrq.gov/clinic/uspstf/uspsglau.htm
http://www.scientificamerican.com/article.cfm?chanID=sa003&articleID=000EF2AE-7C
3F-1D0A-8E49809EC588EEDF


BB

>I would suggest that the author supply the statistics on thse patients
> who are not helped by the drops.  There are several classes of drops,
[quoted text clipped - 52 lines]
>>
>> Comments?
 
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