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Medical Forum / Diseases and Disorders / Glaucoma / February 2005xalatan
Has anyone had problems with insomnia from xalatan or lotemax. I take 1 drop of xalatan before bedtime and wondered if i took it in the morning would be okay? James I have many patients on Xalatan and have not had this complaint. That doesn't mean it's not related. You might have to try stopping one at a time (with your doc's permission, of course), or you'll never know which one is causing the insomnia. Good luck, Rick Cohn, MD >Has anyone had problems with insomnia from xalatan or lotemax. not for me with Xalatan. >I take 1 >drop of xalatan before bedtime and wondered if i took it in the morning >would be okay? Pharmacia stresses that Xalatan is intended for evening use. I don't actually take it anymore, however, I seem to recall getting some annoying side effect (maybe dry eyes) after taking it. Obviously, if you're sleeping, you won't notice it (which is probably why they suggest evening use). I think this may have been discussed here earlier. Maybe try a search at Google (groups.google.com?). The drug info doesn't seem to indicate insomnia as a side effect for either product (but I'm a little tired, so everything is a little blurry). http://www.rxlist.com/cgi/htsearch.cgi?method=boolean&format=builtin-short&sort= score&config=htdig&restrict=&exclude=&words=LATANOPROST+and+side+and+effects&go_ key.x=9&go_key.y=9 http://www.rxlist.com/cgi/htsearch.cgi?method=boolean&format=builtin-short&sort= score&config=htdig&restrict=&exclude=&words=LOTEPREDNOL+and+side+and+effects&go_ key.x=9&go_key.y=9 Perhaps it's something else you're taking, or something else is causing it. This site used to check drug interactions (If it's still there, it may help) http://www.drugdigest.org/DD/Interaction/ChooseDrugs/ - --- Norman Please reply via group. E-mail ID does not exist. > Has anyone had problems with insomnia from xalatan or lotemax. I take 1 > drop of xalatan before bedtime and wondered if i took it in the morning > would be okay? > > James I am wondering why all these IOP lowering drugs have warnings against infection in the product information. Is the danger of infection greater with these drugs greater than with Visine for instance. Why are all these drug manufacturers protecting themselves against the danger of infection? My experiment with vitamin C did not work too well, which leaves THC as the only safe alternative. Xalatan has a short clinical history. This drug is also a hormone and I am not convinced that taking a hormone for years and years is safe especially one with a short history of clinical usage. I am also worried that this drug changes eye color. I don't really want to have eyes with two different colors. I also understand that your IOP is highest at night. This suggests that a dosage of THC at night would have maximum effect with minimal psychogenic side effects. Am I the only one teed off that no research is being done here? I know I am pounding this subject into the ground but I think it deserves it. > Has anyone had problems with insomnia from xalatan or lotemax. I take 1 > drop of xalatan before bedtime and wondered if i took it in the morning > would be okay? > > James My GS said it was okay to take Xalatan in the morning, even though it is labeled for use in the evening. I think that using Xalatan in the p.m. prolongs its effects, as the eye is subsequently closed. DrG Interesting deduction. And it is valid for any drop, not only Xalatan, isn't it? Small pupil > I think that using Xalatan in the p.m. prolongs its effects, as the eye > is subsequently closed. > > DrG >Interesting deduction. And it is valid for any drop, not only Xalatan, isn't it? > [quoted text clipped - 4 lines] >> >> DrG In the absence of data, my wild guess is "not valid". After medicine application and a couple of minutes with a closed eye, the medicine has diffused into the eyeball through the cornea. Then a few blinks and normal tearing will clear the external eye of almost all medicine, and the process is complete. After that maybe you could even go swimming without much effect? John. > >Interesting deduction. And it is valid for any drop, not only Xalatan, isn't it? > > [quoted text clipped - 13 lines] > > John. There is some research to suggest that p.m. dosing results in more even IOP control. Also, since conjunctival redness is a side effect of prostaglandin analogues, it might be better to have this occur at night rather than in the daytime. DrG >> >Interesting deduction. And it is valid for any drop, not only >Xalatan, isn't it? [quoted text clipped - 24 lines] > >DrG Thanks. I can easily live with redness, but my really annoying side effect (I take Xalatan, Betagan and Alphagan P) is that my eyelids itch and itch and itch. Which medicine is guilty? Are there any additional drops that would alleviate this? John It's been mentioned several times here, including by Dr. Cohn, that Alphagan often causes allergic reactions. I developed contact dermatitis with it. If that's your problem, I'd guess you'll need to switch meds. Talk to your doctor. Laura >I can easily live with redness, but my really annoying side >effect (I take Xalatan, Betagan and Alphagan P) is that my >eyelids itch and itch and itch. Which medicine is guilty? Are >there any additional drops that would alleviate this? >It's been mentioned several times here, including by Dr. Cohn, that >Alphagan often causes allergic reactions. I developed contact [quoted text clipped - 7 lines] >>eyelids itch and itch and itch. Which medicine is guilty? Are >>there any additional drops that would alleviate this? Thanks much Laura. Here is Dr. Ritch's message from an "Alphagan AND itch" search of my saved articles: ======================= TNARTLADY@webtv.net (\( TN Artist, trish,tn \)) wrote in message news:<26259-40951B02-56@storefull-3256.bay.webtv.net>... > My pharmacy is OUT of my Rescula drops I use in the am , I use xalatan > in the pm - Question --I have Alphgan P here that was used for the [quoted text clipped - 4 lines] > > No, not really...but relax....Gosh, Trish, you need to take a deep breath or something. First of all, Rescula is a fairly worthless medication...it lowers IOP by maybe a point or two. Alphagan is a much better medication in general. It usually lowers IOP by 5 to 10 points. Anyway, if you tolerate the Alphagan, you may want to ask your doc if you can stay on it long term...just a thought. Alphagan can cause a little dry mouth and fatigue in some, and quite a few folks become allergic to it eventually, causing redness and itch (which goes away after the drop is discontinued). Think about it. Take it easy, Dr. C ================ I wonder if there is a difference between straight Alphagan and the P version of Alphagan in this allergic reaction. For what little it's worth, at the time of insertion Alphagan P seems totally mild. John I think that's been discussed too, although I don't remember it as clearly. I seem to recall that the two forms of Alphagan have different preservatives, and the "P" version is milder. However, it can still cause an allergic reaction. It was the "P" form I didn't get along with, albeit I developed my reaction after being on straight Alphagan for awhile and then on the "P" version for just a few months. Laura >I wonder if there is a difference between straight Alphagan and >the P version of Alphagan in this allergic reaction. For what >little it's worth, at the time of insertion Alphagan P seems >totally mild. |
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