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Medical Forum / Diseases and Disorders / Glaucoma / May 2004

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Questions about Lumigan

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Gisele - 25 May 2004 14:51 GMT
Hello, I am new to the group and would greatly appreciate any
information, advice and help.

I was diagnosed with glaucoma in both eyes in 1999, aged 42.  Pressure
of 30 in both eyes, no family history of glaucoma.  Betagan twice
daily kept my pressures at around 16 and 19 until three months ago
when they rose to 19 and 23.  The hospital prescribed Xalatan.  I
immediately reacted to the drops, very red, sore eyes and it was
discovered at my next examination, two months later that both eyes had
a pressure of 23.

I was prescribed Lumigan and told that I would experience some redness
for the first week - but that since my eyes were already quite red I
probably wouldn't notice this.  I was given a follow up appointment
for July.  I'm in the UK and our National Health Service is not very
helpful.

A few days after I started using Lumigan, my eyes were both still
sore, I now also have headaches and my eyelids have swollen up to the
extent that I can't go out socially and my business is also suffering.

I feel quite low, to be honest, really very depressed about the
situation.

Is Lumigan a last resort medication?  Is it what is prescribed because
nothing else will work and the next step is surgery?  If Lumigan
works, will I always have soreness, redness, swelling, headaches (not
to mention blurred vision)?  I know there are so many things that are
worse than glaucoma but I feel quite devastated by the changes in my
eyes and the fact that my looks, confidence and personality have been
affected in this way.

Sorry if this is all a bit vague but it's a been quite a shock -
Betagan seemed to work for such a long time, I had some minimal
irritation but it was nothing compared with this and I'm wondering
what the future holds.

Thanks in anticipation and apologies for rambling
Sherry - 25 May 2004 15:08 GMT
<snip>

> A few days after I started using Lumigan, my eyes were both still
> sore, I now also have headaches and my eyelids have swollen up to
[quoted text clipped - 11 lines]
> the changes in my eyes and the fact that my looks, confidence and
> personality have been affected in this way.

OMG! With a reaction like that I would have contacted my doctor
IMMEDIATELY!  Call NOW!  Tell them you're having an allergic reaction
to a medication.  Some redness is one thing, but migraines and
swelling is something else!

There are a lot of other medications they can try.

Sherry
Leigh Melton - 25 May 2004 21:47 GMT
><snip>
>>
[quoted text clipped - 9 lines]
>
>There are a lot of other medications they can try.

I agree with Sherry.  I'm using Lumigan now in my left eye and it's
bright pink all the time from it (my glaucoma specialist said this
would last for about three weeks) but the symptoms you describe sound
really out of bounds for a "normal" reaction (normal of course being a
relative term!).  

Leigh

--
Consequences, shmonsequences, as long as I'm rich.  - D. Duck
Paul Williamson - 25 May 2004 21:14 GMT
Hello Gisele,

I can't help you with your queries about the medication, but I am sure
there are others on the group who will.

I noticed your comment about being in the UK and not finding the National
Health Service very helpful.  I am sorry this has been your experience.  
I have two children (now adults) who got glaucoma when they were very
young (5 or 6 years old) as a result of Juvenile Rheumatoid Arthritis,
and they have received excellent treatment for around 25 years now.

It may be that I can ask their specialist to suggest some way that you
can get more satisfactory treatment, so if you would like me to make some
enquiries for you please contact me by direct e-mail and let me know
whereabouts you are in the UK.

Meanwhile all my best wishes to you - I hope you soon resolve your
difficulties.

Paul

>Hello, I am new to the group and would greatly appreciate any
>information, advice and help.
[quoted text clipped - 35 lines]
>Thanks in anticipation and apologies for rambling
>.
Laura - 26 May 2004 00:36 GMT
So sorry about the problems you're having...

I can't answer all your questions.  But as to Lumigan being a last
resort medication:  Well, from what my doctor tells me, I believe it
IS a very strong medication.  But maybe your doctor can try combining
meds?  I myself am on 3 glaucoma drops at once.  I think the idea is
that multiple meds may work where one alone can't.

Laura

>Is Lumigan a last resort medication?  Is it what is prescribed because
>nothing else will work and the next step is surgery?  If Lumigan
[quoted text clipped - 3 lines]
>eyes and the fact that my looks, confidence and personality have been
>affected in this way.
David L.W. - 26 May 2004 02:02 GMT
I was also diagnosed with glaucoma in 1999. I was put on Alphagan and Timoptic.
When these didn't work after a period of time, my MD added Xalatan, which a
member of the prostaglandin family.  These drugs are commonly used along with
other glaucoma drugs, and they usually start with Xalatan.  I did have some
irritation, but not like yours, and it did lessen with time.  My doctor later
switched me over to Travatan, and then to Lumigan, which does seem to work the
best.  It gave me the same side effects at first, but they went away with time.
I hope yours will lessen with time, too.  

Good luck,
David(Houston, Texas)
Reason - 26 May 2004 11:46 GMT
My IOP (left eye only) started above 40.
The specialist prescribed Xalatan and Alphagan - one drop each per day.
He said the X would do most of the work, and the A would drop a few points
more.
They got the pressure down to about 14.
Great so far.

Then not long after, I started to find that my eye was bloodshot much of the
time.

It turned out that I am allergic to Alphagan.
Although Xalatan worked fine, it was not strong enough on its own.

So the doc said a new drop Lumigan is related to Xalatan but stronger.

I started taking Lumigan one drop per night - no problems.
It is also cheaper and more convenient than two different drops.
It keeps my pressure at about 16.

Docs can tell if an allergy is involved.

Good luck,
Stephen
Bill484923 - 26 May 2004 13:23 GMT
Lumigan is actually the "in " drug right now. It is not a lst resort.
cocktailing of drops is the last resort. Have no fear of surgry a filter
procesure is no big deal and is highly effective. As to your imediate reactions
, get yourself back there imediately. The reactions are far too severe and are
not mormal.
Checkout - 26 May 2004 19:01 GMT
Hello Gisele,

I have had glaucoma for a few years and live in the UK too. I have had
an adverse reaction to medication which was quite severe. I telephoned
the NHS eye clinic and asked to speak to the nursing staff, explained
the situation and was told to come in immediately for treatment. I was
seen by a consultant within an hour and told that I had become
allergic to a preservative in a prescribed drop. The medication was
changed and the problem resolved within two days when I was seen by
the consultant again. Phone up and explain the situation, I'm sure you
will be helped immediately.
 
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