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Medical Forum / Diseases and Disorders / Glaucoma / April 2004

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I.O.P. variance with Corneal Thickness

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Dennis Rekuta - 23 Apr 2004 04:39 GMT
I was first diaganosed with glaucoma in 1993 after a left branchiole
occulusion. I had always been checked for glaucoma so it must have
appeared after my previous change in glasses. It has worsened in the last
two years, progressing from Timolol to Cosopt, and then adding Alphagan,
and finally Lumigan. For the last 6 - 8 months, I.O.P. have been stuck at
mid to high twenties in both eyes. My field tests have not deteriorated,
and there has been no evidence of optic nerve damage, even with moderate
Type 2 Diabetes (A1c ranges 6.0 to 6.5).

In January, my ophthamologist checked the drainage angle (goniscopy)
which seemed fine, and had an "orbscope" (sp?) done to measure corneal
thickness before he considered doing a trab. The measurement has come
back at 620 microns, considerable thicker than the supposed average of
520 - 550 microns. He considers my readings to have been elevated by 5
points because of this, and so yesterdays measurements of L26, R27 were
not as much of a concern as before, and I will be continuing on the drops
only.

Checking resources from the FAQ's and Google, the adjustment ranges to
I.O.P. for corneal thickness varied, and I was unable to get a hold of
the data that indicates the sliding scale used.

Is 5 points a reasonable adjustment for a tonoscope reading when the
cornea is at 620 microns?

Dennis
Rick Cohn, M.D. - 24 Apr 2004 02:46 GMT
> Is 5 points a reasonable adjustment for a tonoscope reading when the
> cornea is at 620 microns?
>
> Dennis

That's fairly close to the mark, Dennis.  The rule of thumb I use is 1
point of IOP variation for every 20 microns off normal (I use an
average of 540 microns).  For instance, a patient with a corneal
thickness of 480 microns is 60 microns thinner than normal which would
account for an IOP variation of approximately 3 mm Hg.  In other
words, if I measure an IOP of 23 in that patient, it might really be
26 mm Hg inside the eye.  His/her cornea is easier than normal to
flatten because it is so thin.  Hope that helps.
--Rick Cohn, MD
Glaucoma Specialist
Winter Park, FL
Dennis Rekuta - 24 Apr 2004 21:43 GMT
> > Is 5 points a reasonable adjustment for a tonoscope reading when the
> > cornea is at 620 microns?
[quoted text clipped - 12 lines]
> Glaucoma Specialist
> Winter Park, FL

Thanks Dr. Cohn. That is one more of my problems under control for the
moment. ;-)

Dennis
 
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