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Medical Forum / Diseases and Disorders / Epilepsy / January 2005Dilantin
Hi All Is anyone out there still on Dilantin like me? If so, do you have times where the level rises very quickly and you start feeling really irritable and tired then your sense of balance and even walking properly isn't possible? The reason I ask is because that's what happened to me over the last couple of weeks and I ended up in ER a few days ago. What's weird is that I made no adjustment to my meds and took them at the same time. My GP had just received a blood level which was slightly above the therapeutic range and lowered the dosage and when it was taken in ER it was way above what she had received back. Has anyone else had this experience and what was the follow-up? Cheers Fran >Hi All > [quoted text clipped - 11 lines] >Cheers >Fran Are you taking any other medications? There are a number of medications which, by interacting with Dilantin, can cause the Dilantin level to fluctuate significantly. Best, Bob Robert A. Fink, M. D. Neurological Surgery 2500 Milvia Street Suite 222 Berkeley, CA 94704-2636 USA 510-849-2555 ********************************** NOTE: The material above is not "medical advice". Medical advice can only be given after an in-person contact between doctor and patient. ********************************** Hi. This Re:Dilantin message puzzles me. It seems to be a response to a message that was presumably mailed this afternoon. However, I never received or read the original message. This seems to be occurring more and more within this alt.support.epilepsy group. So many Re:Messages minus the original. Any advice or wisdom? Thanks, Tim > Hi. This Re:Dilantin message puzzles me. It seems to be a response to a > message that was presumably mailed this afternoon. However, I never [quoted text clipped - 4 lines] > Any > advice or wisdom? Thanks, Tim Headers of the posts are below (I hope they don't mind me displaying them here, although trolls who wanted them have them already anyway). Is there anything in path or addressing (they're in New Zealand) that you might be filtering out? E.G. If you have a filter set to Discard messages that have a Hidden Source sender, in mails or groups? the <>s work the same way as [ ]s and make the address Invisible to Phisher robots. Although you can see that opening the headers manually, worked below. 2 years ago I used to get lots of 'trash mails' that appeared on 'here', that others complained they never got. When I changed my Newsreader, after being away (and deleting the group), the messages I had under the First Newsreader offered to me by the operating system, Disappeared when I subscribed on the Second one when I resubscribed. G./ Headers of the message you didn't get --> Path: border1.nntp.dca.giganews.com!nntp.giganews.com!news.maxwell.syr.edu!sn-xit-04!sn-xit-12!sn-xit-06!sn-post-01!supernews.com!corp.supernews.com!not-for-mail From: "kompressor" <franryan@xtra.co.nz> Newsgroups: alt.support.epilepsy Subject: Dilantin Date: Sat, 15 Jan 2005 14:05:40 -0500 Organization: www.talkaboutsupport.com Message-ID: <7bd07f803e4acf3fd7739b46caeed2a5@localhost.talkaboutsupport.com> X-Newsreader: www.talkaboutsupport.com Content-Type: text/plain; X-Complaints-To: abuse@supernews.com Lines: 16 Xref: number1.nntp.dca.giganews.com alt.support.epilepsy:67276 Thank you Robert. Yes, just a controlled-release iron supplement (ferrogradumet)because the Dilantin caused anaemia a few years ago. I'm a vegetarian but had no previous probs with anaemia until Dilantin came on the scene. > Hi All > [quoted text clipped - 11 lines] > Cheers > Fran Fran, I've been taking dilantin approaching two years now. The symptoms you decribe definitely conform to an overdose. With dilantin, once your blood is saturated (at high end of theraputic range) just a little extra (50-100mg) can send you into an overdose condition. This happens because concentrations of the drug rise non-linearly (much faster proportional to incremental dose) once blood is saturated. Two guesses on what happend to you: 1) You accidently took an extra dose. I put my day's supply in a pill box the night before to avoid overdose. It's very easy to forget you've taken your pills, especially if you split dose in half like I do. 2) You drank alcohol in significant volume. Alcohol is eliminated through the liver by the same enzymes that eliminate Dilantin. When you drink it takes longer for the body to eliminate Dilantin allowing your blood levels to climb. 3) You took some other drug that interacted with dilantin. Your doctor should be aware of all drugs you are taking. I don't take anything without first consulting my doctor and pharmacist as an overdose can kill you or perminantly damage your liver. My money is on guess (1) as I've come close many times to taking one too many doses in a day. Hope you don't have another bad experience. Regards, Bill One other possibility that has happened to me (which may or may not be the case for anyone else). Slowing metabolism. In my case, an anti-depressant seems to have slowed my metabolism down to the point that I no longer need as much dilantin. I first begin to feel a different type of headache/head pressure. It takes me a few days to figure out what the problem is, because I've had headaches all my life, but it is a different feeling. Then by the time my pressure turns to dizziness and severe brain fog I realize I'm toxic. I usually feel best at the low end of the required level, sometimes just below (like an 8 or 9, when 10-10 is normal). Lainie Thanks all for your comments and suggestions. The iron supplement has been removed because tests revealed toxicity from an 'iron overload'. The dilantin has been significantly reduced also and I'm feeling decidedly healthier. Cheers Fran |
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