Medical Forum / Diseases and Disorders / Epilepsy / November 2004
Aspartame / Phenylalanine
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Daz_n_Pat - 31 Oct 2004 06:59 GMT I have a word document which is a composite of a lot of information I have found regarding the effects of aspartame / phenylalanine (contained in artificial sweeteners) on people with various ailments.
As for myself, I have found that they have a PROFOUND effect on my seizures. Eating sweets containing artificial sweeteners causes me to have extremely violent cluster seizures.
Anyone interested in a little light reading on the subject can email me on darryl.gaye@paradise.net.nz and I will send you this document for your perusal.
Cheers.
Darryl.
cabbagecaff - 02 Nov 2004 00:14 GMT How interesting! My daughter has been off Aspartame for about 9 months and free of all the strange dizzy, sick, fainting problems she previously had. I KNOW that it was aspartame that caused her problems. Now my husband has had 2 seizures out of the blue -and I DID wonder if he had been having too much aspartame, but dismissed it, as I felt perhaps I was being paranoid! Now I am DEFINATELY going to get rid of every single trace of the blessed stuff -it is in EVERY lemonade in England, and almost all chewing gums, childrens vitamin tablets, brearth freshener squares, and obviously every sugar free pudding, and sweets. There is a lot of frightening information on the net about this stuff -and I don't understand why it is allowed to be in all our foodstuffs. Bring back sugar, and honey and natural sweet ingredients. Thanks Darryl, for bringing this to folks attention. I spread the word here in England all the time! Cathy
Paul Dalrymple - 02 Nov 2004 16:01 GMT > How interesting! My daughter has been off Aspartame for about 9 months > and free of all the strange dizzy, sick, fainting problems she [quoted text clipped - 11 lines] > Thanks Darryl, for bringing this to folks attention. I spread the word > here in England all the time! The following was posted in April, 2001 by an AOL user under "ASPARATAME Users Beware". I had already stopped using any diet products b/c I suspected it was triggering my seizures- even things such as sugar-free cough drops or mints! I enjoyed Diet Coke and was using it b/c of weight problems, knowing how regular sodas are nothing but sugar & calories. Relatives of mine in the health industry said I was full of BS, wrong, etc. But I saved the post just for this reason. ----------------- I know there have been a lot of posts about the dangers of aspartame but after reading this, I thought it important to share with you.
"Aspartame" marketed as 'NutraSweet', 'Equal', and 'Spoonful'. In the keynote address by the EPA, they announced that there was an epidemic of multiple sclerosis and systemic lupus, and they did not understand what toxin was causing this to be rampant across the United States. I explained that I was there to lecture on exactly that subject.
When the temperature of Aspartame exceeds 86 degreesF, the wood alcohol in Aspartame converts to formaldehyde and then to formic acid which in turn causes metabolic acidosis. (Formic acid is the poison found in the sting of fire ants). The methanol toxicity mimics multiple sclerosis in error. The multiple sclerosis is not a death sentence, where methanol toxicity is.
In the case of systemic lupus, we are finding it has become almost as rampant as multiple sclerosis, especially with Diet Coke and Diet Pepsi drinkers.
Also with methanol toxicity, the victims usually drink three to four 12oz. cans of them per day, some even more. In the cases of systemic lupus, which is triggered aby Aspartame, the victim usually does not know that the aspartame is the culprit . The victim continues its use, aggravating the pupus to such a degree, that sometimes it becomes life-threatening. When we get people off the aspartame, those with systemic lupus usually become symptomatic. Unfortunately, we cannot reverse this disease.
On the other hand in the case of those diagnosed with MS, when in reality, the disease is methanol toxicity most of the symptoms disappear. We have seen cases where their vision has returned and even their hearing has returned. This also applies to cases of tinnitus.
During a lecture I said, "if you are using Aspartame, NutraSweet, Equal, Spoonful, etc.) and you suffer from fibromyalgia symptoms, spasms, shooting pains, numbness in your legs, cramps, vertigo, dizziness, headaches, tinnitus, joint pain, depression, anxiety attacks slurred speech, blurred vision, or memory loss, you probably have Aspartame Disease."
Aspartame changes the brain's chemistry. It is the reason for severe seizures. This drug changes the dopamine level in the brain imagine what this drug does to patients suffering from Parkinson's Disease. This drug also causes Birth Defects.
There is absolutely no reason to take this product. It is NOT a diet product! The Congressional record said "It makes you crave carbohydrates and will make you FAT". Dr. Roberts stated that when he got patients off aspartame, their average weight loss was 19 pounds per person. The formaldehyde stores in the fat cells, particularly in the thighs..."
The article goes on to say..."I assure you that MONSANTO, the creator of Aspartame knows how deadly it is. They fund the American Diabetes Association, American Dietetic Association, Congress, and the Conference of the American College of Physicians. The New York Times on Nov. 15, 1996 ran a article on how the American Dietetic Association takes money from the food industry to endorse their products.
Therefore, they cannot criticize any additives or tell about their link to Monsanto. How bad is this? We told a mother who had a child on NutraSweet, to get off the product. The child was having grand mal seizures every day. The mother called her physician,who called the ADA who told the doctor not to take the child off the NutraSweet. We are still trying to convince the mother that the aspartame is causing the seizures.
Every time we get someone off of aspartame, the seizures stop. If the baby dies you know whose fault it is, and what we are up against. There are 92 documented symptoms of aspartame, from coma to death. The majority of them are all neurological, because the aspartame destroys the nervous system. ....
The article is quite lengthy and goes on to blame Gulf War Syndrome on Aspartame as cases of Diet Soda were stored out in the scorching desert heat and turned the aspartame more deadly.
After reading the article, there was no question in my mind that aspartame should be avoided at all costs.
I believe the article was by Dr. H.J. Roberts, a diabetic specialist and world expert on aspartame poisoning. It also refers to Dr. Russell Blaylock, author of EXCITOTOXINS, THE TASTE THAT KILLS.
Klenow - 02 Nov 2004 01:31 GMT > I have a word document which is a composite of a lot of information I have > found regarding the effects of aspartame / phenylalanine (contained in [quoted text clipped - 11 lines] > > Darryl. I've been looking through the scientific literature on aspartame and seizures and it seems pretty clear to me that aspartame does not induce seizures or lower seizure threshold in animal epilepsy models and does not lower seizure threshold in humans. Yet, the controversy continues. I'd be very interested to see the literature you've acquired to compare it with what I've found. I'd like to compare the methodology just to satisfy my curiosity. Can you email me a copy? I've sent a copy of this to the address you provided.
Thanks.
Theo - 02 Nov 2004 09:13 GMT > I have a word document which is a composite of a lot of information I > have found regarding the effects of aspartame / phenylalanine [quoted text clipped - 11 lines] > > Darryl. I was told long ago to stay away from the stuff. I dont know how valid the idea is, but its not like telling someone to stay away from water.
Daz_n_Pat - 02 Nov 2004 20:19 GMT >> I have a word document which is a composite of a lot of information I >> have found regarding the effects of aspartame / phenylalanine [quoted text clipped - 14 lines] > I was told long ago to stay away from the stuff. I dont know how valid > the idea is, but its not like telling someone to stay away from water. Have you found it's made any improvements since staying away from it? Darryl.
Theo - 03 Nov 2004 01:54 GMT "Daz_n_Pat" <daryl.gaye@paradise.net.nz> wrote in news:x5Rhd.29187 $mZ2.939675@news02.tsnz.net:
>>> I have a word document which is a composite of a lot of information I >>> have found regarding the effects of aspartame / phenylalanine [quoted text clipped - 17 lines] > Have you found it's made any improvements since staying away from it? > Darryl. its been awhile but no I dont think so. maybe it did and I just dont notice it.
Rich Murray - 03 Nov 2004 00:46 GMT *********************************************************************
Rich Murray, MA Room For All rmforall@comcast.net 1943 Otowi Road Santa Fe, New Mexico 87505 USA 505-501-2298 http://groups.yahoo.com/group/aspartameNM/messages group with 135 members, 1,129 posts in a public, searchable archive.
The moderated newsgroup, bionet.toxicology , has accepted 20 of my long reviews since March 24:
Dr. Charles "Chuck" A. Miller III rellim@tulane.edu Associate Professor of Environmental Health Sciences 374 Johnston Building, SL29 Tulane Univ. School of Public Health and Tropical Medicine 1430 Tulane Avenue New Orleans, LA 70112 (504)585-6942 Bionet.toxicology news group http://www.bio.net/hypermail/toxicol/current
http://groups.yahoo.com/group/aspartameNM/message/1128 hangover symptoms from methanol from dark wines and liquors or 11% methanol part of aspartame, review of research: Jones AW 1988: Murray 2004.10.23 rmforall
Fully 11% of aspartame is methanol -- 1,120 mg aspartame in 2 L diet soda, almost six 12-oz cans, gives 123 mg methanol (wood alcohol). However, about 30% of the methanol remains in the body as cumulative durable toxic metabolites of formaldehyde and formic acid, 37 mg daily, a gram every month, accumulating in and affecting every tissue -- over 60 times the USA EPA limit for formaldehyde in drinking water.
Aspartame is made of phenylalanine (50% by weight) and aspartic acid (39%), both ordinary amino acids, bound loosely together by methanol (wood alcohol, 11%). Similar amounts of methanol in many fruits and vegetables, locked up in complex pectin molecules, and always paired with ethanol, its natural antidote, are not usually released by human digestion and so are harmless. But the readily released methanol from aspartame is within hours largely turned by the liver into formaldehyde and then formic acid, both potent, cumulative toxins.
Red wine contains twice as much methanol as does diet soda as an impurity, about one part in ten thousand. It is the natural conversion by the body of this methanol into formaldehyde and formic acid that is the main cause of the well known "morning after" hangover symptoms: headache, nausea, weakness, impaired memory, irritability, anxiety, "brain fog", body pains -- the same symptoms as aspartame victims.
Jones AW. Elimination half-life of methanol during hangover. Pharmacol Toxicol. 1987 Mar; 60(3): 217-20. PMID: 3588516
" But higher blood-methanol concentrations are definitely associated with higher blood-ethanol in this sample of Swedish drinking drivers.
Frequent exposure to methanol and its toxic products of metabolism, formaldehyde and formic acid, might constitute an additional health risk associated with heavy drinking in predisposed individuals. " Jones AW 1988
Forensic Sci Int. 1988 Jun; 37(4): 277-85. Relationship between the concentration of ethanol and methanol in blood samples from Swedish drinking drivers. Jones AW, Lowinger H. Department of Alcohol Toxicology, University Hospital, Linkoping, Sweden. Jones AW has 341 items in PubMed.
http://groups.yahoo.com/group/aspartameNM/message/1106 hangover research relevant to toxicity of 11% methanol in aspartame (formaldehyde, formic acid): Calder I (full text): Jones AW: also some methanol from fruit pectin in colon: Murray 2004.09.11 rmforall
http://bmj.bmjjournals.com/search.dtl search to get free full text British Medical Journal 1997 (4 January); 314(7073): 2. Ian Calder, F.R.C.A. [ Tel/Fax: 0171 720 9279 Consultant Anaesthetist at the National Hospital for Neurology and Neurosurgery, London WCIN 3BG, UK ]
Editorials Hangovers: Not the ethanol - perhaps the methanol
" Pawan compared the hangover produced by different types of drink (but only one brand of each) in his study of 20 volunteers. The severity of hangover symptoms declined in the order of brandy, red wine, rum, whisky, white wine, gin, vodka, and pure ethanol.(6) Vodka and pure ethanol caused only mild headaches in two volunteers. "
6. Pawan GL. Alcoholic drinks and hangover effects. Proc Nutr Soc 1973 May; 32: 15A. PMID: 4760771
J.A. Oppermann's Searle Co. lab proved that 30% of the methanol in aspartame fed once to monkeys remained -- surely as formaldehyde and formic acid in all tissues (1973, 1976, 1979).
This was confirmed by an expert team at the University of Barcelona (Trocho C, Alemany M, et al, 1998): " ...the binding of methanol-derived carbon [ from low levels of aspartame fed to rats for 10 days ] to tissue proteins was widespread, affecting all systems, fully reaching even sensitive targets such as the brain and retina...These are indeed extremely high levels for adducts of formaldehyde, a substance responsible for chronic deleterious effects (33), that has also been considered carcinogenic. " Prof. Mari? Alemany alemany@bio.ub.es Life Sci. 1998 June 26; 63(5): 337-49. PMID: 9714421
http://groups.yahoo.com/group/aspartameNM/message/1016 President Bush & formaldehyde (aspartame) toxicity: Ramazzini Foundation carcinogenicity results Dec 2002: Soffritti: Murray 2003.08.03 Ann N Y Acad Sci. 2002 Dec; 982: 87-105. Results of long-term experimental studies on the carcinogenicity of formaldehyde and acetaldehyde in rats. M. Soffritti et al. Cancer Research Center, European Ramazzini Foundation for Oncology and Environmental Sciences, Bologna, Italy. crcfr@tin.it p. 88 " The sweetening agent aspartame hydrolyzes in the gastrointestinal tract to become free methyl alcohol, which is metabolized in the liver to formaldehyde, formic acid, and CO2. (11) " Ref. (11) is: Medinsky MA & Dorman DC. 1994; Assessing risks of low-level methanol exposure. CIIT Act. 14: 1-7.
http://groups.yahoo.com/group/aspartameNM/message/1128 hangover symptoms from methanol from dark wines and liquors or 11% methanol part of aspartame, review of research: Jones AW 1988: genotoxicity in human cells proven, Rencuzogullari E et al 2004 Aug: Murray 2004.10.23 rmforall
Drug Chem Toxicol. 2004 Aug; 27(3): 257-68. Genotoxicity of aspartame. Rencuzogullari E, Tuylu BA, Topaktas M, Ila HB, Kayraldiz A, Arslan M, Diler SB. Biology Dept, Faculty of Arts and Sciences, Natural and Applied Sciences Institute, Cukurova University, Adana, Turkey. reyyup@mail.cu.edu.tr PMID: 15478947 This expert team found DNA damage in human lymphocytes. Rencuzogullari E has 4 other similar studies in PubMed.
http://groups.yahoo.com/group/aspartameNM/message/1088 Murray, full plain text & critique: chronic aspartame in rats affects memory, brain cholinergic receptors, and brain chemistry, Christian B, McConnaughey M et al, 2004 May: 2004.06.05 Pharmacol Biochem Behav. 2004 May; 78(1): 121-7. PMID: 15159141 Mona M. McConnaughey, Ph.D. Research Assistant Professor 252-744-2756 mcconnaugheym@mail.ecu.edu Twelve rats fed aspartame at otherwise nontoxic levels for 4 months forgot how to turn right to get a treat, and had specific brain changes.
http://groups.yahoo.com/group/aspartameNM/message/1067 eyelid contact dermatitis by formaldehyde from aspartame, Hill AM & Belsito DV, Nov 2003: Murray 2004.03.30 Contact Dermatitis. 2003 Nov; 49(5): 258-9. PMID: 14996049 A mysterious dermatitis was caused by a dose the same as two packets Equal daily.
http://groups.yahoo.com/group/aspartameNM/message/846 aspartame in Merck Maxalt-MLT worsens migraine, AstraZeneca Zomig, Eli Lilly Zyprexa, J&J Merck Pepcid AC (Famotidine 10mg) Chewable Tab, Pfizer Cool Mint Listerine Pocketpaks: Murray 2002.07.16 rmforall
Migraine MLT-Down: an unusual presentation of migraine in patients with aspartame-triggered headaches. Newman LC, Lipton RB Headache 2001 Oct; 41(9): 899-901. [ Merck 10-mg Maxalt-MLT, for migraine, has 3.75 mg aspartame, while 12 oz diet soda has 200 mg. ] Headache Institute, St. Lukes-Roosevelt Hospital Center, New York, NY Department of Neurology newmanache@aol.com Albert Einstein College of Medicine, Bronx, NY Innovative Medical Research RLipton@aecom.yu.edu
http://groups.yahoo.com/group/aspartameNM/message/855 Blumenthall & Vance: aspartame chewing gum headaches Nov 1997: Murray 2002.07.28 rmforall
Harvey J. Blumenthal, MD, Dwight A Vance, RPh Chewing Gum Headaches. Headache 1997 Nov-Dec; 37(10): 665-6. Department of Neurology, University of Oklahoma College of Medicine, Tulsa, USA. neurotulsa@aol.com Aspartame, a popular dietetic sweetener, may provoke headache in some susceptible individuals. Herein, we describe three cases of young women with migraine who reported their headaches could be provoked by chewing gum sweetened with aspartame. [ 6-8 mg aspartame per stick chewing gum ]
http://groups.yahoo.com/group/aspartameNM/message/1077 eight depressed people react strongly to aspartame, Prof. Ralph G. Walton, MD, 1993 double-blind study, full text: Murray 2004.04.26 rmforall They reported with aspartame, compared to placebo, much higher levels of anxiety, poor memory, nausea, depression, anger, and malaise. A 60 kg subject would have had 1800 mg aspartame, the same as nine 12-oz diet sodas, daily for 7 days. 330-740-3621 rwalton193@aol.com PMID: 8373935
http://groups.yahoo.com/group/aspartameNM/message/1124 8 more Rapid Responses to Aspartame and its effects on health, BMJ: Murray 2004.10.18 rmforall
http://groups.yahoo.com/group/aspartameNM/message/1120 5 critical Rapid Responses to Aspartame and its effects on health, Michael E J Lean and Catherine R Hankey, BMJ 2004; 329: 755-756: Murray 2004.10.05 rmforall
http://groups.yahoo.com/group/aspartameNM/message/1117 Aspartame and its effects on health, Michael E.J. Lean, Catherine R. Hankey, Glasgow UK, British Medical Journal: 11% methanol component of aspartame, and same level of methanol in dark wines and liquors, turns to formaldehyde and formic acid, the main cause of chronic hangover symptoms: Murray 2004.10.04 rmforall http://bmj.bmjjournals.com/cgi/eletters/329/7469/755#76712
http://groups.yahoo.com/group/aspartameNM/message/927 Donald Rumsfeld, 1977 head of Searle Corp., got aspartame FDA approval: Turner: Murray 2002.12.23
http://groups.yahoo.com/group/aspartameNM/message/1065 politicians and celebrities hooked on diet sodas (aspartame): Murray 2004.03.24 Senator John Edwards still has a dozen Diet Cokes daily -- a gallon, which gives as much methanol as a half-gallon of red wine.
http://groups.yahoo.com/group/aspartameNM/message/1071 Aspartame (NutraSweet, Equal, Canderel, E951), after eight years of controversy, was suddenly and capriciously approved in July 1981 by a new FDA commissioner, Arthur Hull Hayes, Jr ( just appointed by President Reagan ), disregarding the negative vote of his own Scientific Board of Inquiry.
http://google.com gives 249,000 websites for "aspartame", with the top 8 of 10 listings being anti-aspartame, while http://groups.google.com finds on 700 MB of posts from 20 years of Usenet groups, 101,000 posts. http://news.google.com many recent aspartame items from 4500 sources. http://www.ncbi.nlm.nih.gov/PubMed lists 771 aspartame items.
http://groups.yahoo.com/group/aspartame/messages 833 members, 17,549 posts in their public archive http://www.presidiotex.com/aspartame/ Aspartame Victims Support Group bryanth@presidiotex.com
http://www.dorway.com/enclosur.html http://groups.yahoo.com/group/aspartameNM/message/53 aspartame history Part 1/4 1964-1976: Gold: Murray 1999.11.06
http://www.holisticmed.com/aspartame/scf2002-response.htm a detailed critique of European Commission Scientific Committee on Food re aspartame ( 2002.12.04 ) http://www.HolisticMed.com/aspartame mgold@holisticmed.com Aspartame Toxicity Information Center Mark D. Gold also Co-Moderator 12 East Side Drive #2-18 Concord, NH 03301 603-225-2110 http://www.holisticmed.com/aspartame/abuse/methanol.html "Scientific Abuse in Aspartame Research"
Many scientific studies and case histories report: * headaches * many body and joint pains (or burning, tingling, tremors, twitching, spasms, cramps, stiffness, numbness, difficulty swallowing) * fever, fatigue, swollen glands * "mind fog", "feel unreal", poor memory, confusion, anxiety, irritability, depression, mania, insomnia, dizziness, slurred speech, sexual problems, poor vision, hearing (deafness, tinnitus), or taste * red face, itching, rashes, allergic dermatitis, hair loss, burning eyes or throat, dry eyes or mouth, mouth sores, burning tongue * obesity, bloating, edema, anorexia, poor appetite or excessive hunger or thirst * breathing problems, shortness of breath * nausea, diarrhea or constipation * coldness * sweating * racing heart, low or high blood pressure, erratic blood sugar levels * hypothryroidism or hyperthyroidism * seizures * birth defects * brain cancers * addiction * aggrivates diabetes, autism, allergies, lupus, ADHD, fibromyalgia, chronic fatigue syndrome, multiple chemical sensitivity, multiple sclerosis, pseudotumor cerebri, Grave's disease, Parkinson's disease, and interstitial cystitis (bladder pain). **********************************************************************
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