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Medical Forum / Diseases and Disorders / Epilepsy / May 2004

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New Drugs, Hip Fracture Rehab, Geriatric Patient

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Mac - 22 May 2004 04:41 GMT
New Drugs, Hip Fracture Rehab, Geriatric Patient

Hi,
My father is recovering from hip surgery, but despite my efforts is not
getting a neurological follow-up at the otherwise full-service and
teaching hospital. His AEDs are minimum therapuetic level Dilantin and
oxcarbamazepine (spelling is likely wrong).

According to these articles (please see below), I strongly suspect that
he would benefit from a change in AED therapy. Why? Because the
drowsiness and/or dizziness and possibly over-eating could be reduced in
the short term, thus allowing him to regain his walking skills faster.
He always had problems with 'sailor's walk', and yes, he was a sailor
but not all his working life. In the long term (he is an 88 year-old),
the rate of loss of bone density caused by AEDs could be reduced.

Here are the articles:

<http://www.princetonhcm.com/public/2003-31-3/report141.html>
Identifying and Managing Adverse Effects of Antiepileptic Drugs

and ../report142.html
Understanding the Role of Bone Health in Seizure Management

If a neurologist needs more info, please contact me at
mogiljan at yahoo dot com.


Thank You!
CyberCafe - 22 May 2004 16:42 GMT
> New Drugs, Hip Fracture Rehab, Geriatric Patient
>
[quoted text clipped - 8 lines]
> drowsiness and/or dizziness and possibly over-eating could be reduced in
> the short term, thus allowing him to regain his walking skills faster.

> He always had problems with 'sailor's walk', and yes, he was a sailor
> but not all his working life. In the long term (he is an 88 year-old),
[quoted text clipped - 13 lines]
>  
> Thank You!

Thanks for providing the links to the articles.  They were informative.
   They did a bone scan on me within the last year.  My hips were just
fine, the spine showed osteoporosis.  I've been postmenopause for quite
a few years and on Dilantin 14 years and calcium intake had been low for
many, many years.  The bone scan technician said weight bearing seems to
 help save the hips from bone loss (one advantage of being over-weight!).

A few years ago I read an article on some of these hip fractures
actually being due to blood clotting disorders (such as factor V Leiden
or activated protein C resistance).

It certainly wouldn't hurt for your father to see his neurologist
because his low drug level of AEDs might be contributing to some of his
problems. I've had more problems at times of more serious health
problems, the ones that have been associated with a prolonged elevated
temperature, but now that I think about it, maybe it was the body stress
and not the fever that produced a few breakthrough symptoms.

There are medications to help prevent bone loss (like Fosamax).
Apparently bone is being made by the body but the loss is greater than
what the body can remake.  Some of these drugs help balance/slow down
that gain/loss ratio a little better.

Barb
Mac - 24 May 2004 08:49 GMT
Hi Barb,
It takes a few months for the calcium to 'kick in', I was told.
Best Wishes
Mac

> There are medications to help prevent bone loss (like Fosamax).
> Apparently bone is being made by the body but the loss is greater than
> what the body can remake.  Some of these drugs help balance/slow down
> that gain/loss ratio a little better.
>
> Barb

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