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Medical Forum / Diseases and Disorders / Epilepsy / November 2006DILANTIN COMEING UP A
positive for barbiturate in a urine test ???? BEWARE GROUP LOOK THIS UP .you go look for a job ect... and come up positive for a barbiturate ?? my doc said no way it will.. hummmmm i need your help on this can you all please take your time looking in on this thanks very much every one that takes DILANTIN WILL COME UP POSITIVE FOR A BARBITURATE IN A URINE TEST iv talked too drug makers of PHENYTOIN) ER (DILANTIN) the FDA ect . make them aware of this little mess up... we all need too know this.. they tell me they did not know this ?? humm let me know if anyone knows this THANKS > positive for barbiturate in a urine test ???? BEWARE GROUP LOOK THIS UP > .you go look for a job ect... and come up positive for a barbiturate ?? [quoted text clipped - 5 lines] > we all need too know this.. they tell me they did not know this ?? humm > let me know if anyone knows this THANKS Which thread would you prefer to talk about this on? was anyone informed about dilantin comeing up like this ?? is all im geting at just wanted people too know it does > was anyone informed about dilantin comeing up like this ?? is all im > geting at just wanted people too know it does Dilantin -is- excreted through urine, although I don't know of it showing up on drug tests. >> was anyone informed about dilantin comeing up like this ?? is all im >> geting at just wanted people too know it does > > Dilantin -is- excreted through urine, although I don't know of it showing up > on drug tests. The body has various methods by which it breaks down the various meds into other chemical compounds and eliminates them from the body. It's a byproduct of the breakdown process of Dilantin/phenytoin that shows up in the urine and triggers a positive on the drug tests, not Dilantin/phenytoin itself. partials were did you find that info ? > partials were did you find that info ? What info? You didn't quote any part of what I said, so I can't tell what you're referring to. Is that a limitation of WebTV? I'm not familiar with WebTV, but almost all programs automatically quote the message that you're responding to and have it sitting there ready for you to add your reply to. Let me know and I'll figure it out if that program doesn't let you quote. all sorry i meant how it breaks down in your body sorry im sorry partials i meant the break down of PHENYTOIN in the urine. comeing up positive for drugs . was just asking were you found that info. sorry i was thinking you could read my mind lol > im sorry partials i meant the break down of PHENYTOIN in the urine. > comeing up positive for drugs . was just asking were you found that > info. sorry i was thinking you could read my mind lol :) That comes from a couple of places. My favorite website for prescription drug information is http://rxlist.com Plug in Dilantin and then select phenytoin sodium by "Generic Name" on the left. Then on the next screen select the Clinical Pharmacology tab. There it describes the metabolism process: "Most of the drug is excreted in the bile as inactive metabolites which are then reabsorbed from the intestinal tract and excreted in the urine.". Then from the website on drug testing at http://www.drugtestinfo.com/faq.htm the offending metabolite is identified: "Will Dilantin or Phenobarbital cause a positive test for barbiturates? . . . Phenytoin (Dilantin) is not a barbiturate; however a metabolite, p-hydroxyphenytoin has minimal cross reactivity on the initial screening test. There is no interference on the confirmatory GC/MS test, therefore, Dilantin (Phenytoin) has no effect on the eventual result for barbiturates.". As it states there, there are 2 tests: initial and confirmatory. The confirmatory GC/MS test needs to be run by a lab if there is a false positive. thanks partials. yes thats the lab test i had done GC/MS it came back negative on the drug screen
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