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Medical Forum / Diseases and Disorders / Epilepsy / January 2006

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Anyone on lamictal that controls botth tonic clonic and absence seizures?

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jess - 16 Jan 2006 21:58 GMT
Hi there,

I am in the process of removing zarontin (ethosuximide) - which
supposedly controls my absence seizures. My neuro would like to try me
on lamictal only.

I have read a few articles about lamictal being able to control both
absence and tc seizures and was wondering if anyone had any experience
or was on lamictal as a monotherapy for both types of seizures.

I was also curious what dosages people were on and if a higher dosage
was needed to control both

Cheers

Jess
purple-cow - 17 Jan 2006 19:13 GMT
Jess,

I want to say to you that Lamictal can be used to control the tonic-clonic
and absence seizures, plus several other seizures as well. But for
yourself, there is no single person, not I, not anyone, and not even
yourself, who is going to be able to say that lamictal, will definitely
work for you. Even if you were to receive feedback replies from the over
50 million people with epilepsy worldwide, the only way that you are going
to find out the utmost truthful answer is by having your doctor to place
you on the lamictal itself. You will then need to go through the process
pertaining to what's called 'pharmacokinetics' in order to search for your
individual therapeutic range. Your therapeutic range may be high or it
might be low. It can also be wide or even narrow. The keyword on this is
*your*. This process may be short and quick, with the doctor's goal of you
having no seizures AND no side effects. But it’s also possible that you may
have severe/intolerable side effects. Now if it appears that there's no
noticeable change at all just yet, then you're going to need to increase
the dosage amount as many times necessary, which might be a long dragged
out process, until you become seizure-free. If you happen to come to a
certain point when it appears that the seizures have been reduced rather
well, but not fully, and that some intolerable side effects are starting
to creep in, then your doctor should either lower the dosage amount and
add-on another antiepileptic medication; or completely wean you off of the
lamictal and repeat the same pharmacokinetics process on a different
antiepileptic medication.

Something you need to remember is that if you do find out that lamictal
(or whatever medication) is going to be right for you, it may not be right
for you forever. Over time, our bodies change, this means that it’s
possible that some changes may need to be done on the medication. For
example, when we become older adults the medication in our bloodstream is
eliminated somewhat slower. So the amount of medication that is consumed
by mouth may need to be somewhat lowered, if necessary.

Hope this helps you.

Bruce
jess - 17 Jan 2006 20:21 GMT
Hi Bruce,

As always thanks for your replies. I have been on 500mg of lamotrigine
for a while as well as zarontin. As you said, with age comes changes
and I am sure that my hormones would have calmed down a wee bit as I
was in puberty when I got epilepsy. So I guess it is fingers crossed. I
have been off zarontin for three days now and have not had any absence
seizures --- yay . To be fair though, Zarontin never really totally
controlled my absene seizures.

One of my big concerns of course is that in the next 5 years, I would
like to fall pregnant and lamotrigine as monotherapy is the safest drug
as far as I can tell.

The other thing that I was wondering is  when you reducing your meds,
how long does it take aproximately for your body to adjust. I.e. is it
as soon as the drug is out your system leaving you with a lower dose or
does it need some time to adjust to the lower dose once the drug is out
your system. Hope that makes sense.

Have a great day

Jess
purple-cow - 18 Jan 2006 05:20 GMT
Jess,

The best thing I can think of concerning an approximate time for the body
to adjust when reducing the medication is probably going to be roughly the
same amount of time it took when you were increasing the medication. Just
in a reverse process. Most likely, you will be tapered off the zarontin
over several weeks. Something that might be a good idea is for you to keep
track of how your body is responding to being tapered off the zarontin, or
any medication. For example, if you start to realize hey, I’m not feeling
so drowsy or dizzy anymore. Heck, write it down so you’ll have record of
what appeared to side effects when you were taking zarontin.

Now about Lamictal and pregnancy. Let me point you to a website that
should give you some helpful information. It is, in my opinion, via the
best fully loaded online website I know of that contains thoroughly
detailed information about epilepsy. The one individual site is, I guess
you could say, titled ‘If a woman takes Lamictal during pregnancy, will it
hurt the baby?’
http://www.epilepsy.com/medications/b_lamictal_pregnancy.html
This next website is going to be the start of a group of websites, title
‘Pregnancy & Motherhood’.
http://www.epilepsy.com/info/women_pregnancy.html
Please notice that in the menu guide on the left hand side of the screen,
there are several more ‘branch sites’ [Pregnancy & epilepsy medications;
The AED Pregnancy Registry; FDA pregnancy categories; AND Advice on
breastfeeding].

As you can tell, all of these individual websites tie into
www.epilepsy.com. It might take you several weeks, maybe even several
months, but if you are really interested in wanting to learn so much more
in detail about epilepsy, a good place to start is through the
epilepsy.com site map, which is located at
http://www.epilepsy.com/sitemap/sitemap.html I guarantee, you are going to
be rather busy going through it. I still haven’t gone through all of it
myself and I found out about it somewhere around the winter of 2004. The
biggest thing that I’m hoping and praying for is to be allowed to return
back to that website’s community forum. For I now know much more about
epilepsy, but still learning proper community forum etiquette.

Glad to help.

Bruce (aka grez-monkey; batman; purple-cow)
 
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