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Medical Forum / Diseases and Disorders / Epilepsy / January 2006

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Medications???

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Mike Kelliher - 10 Jan 2006 02:05 GMT
I would like to know something that maybe only a few really know, or maybe
more but I sure don't.
What is the deal with all the meds under different names but being almost
identical.
All Benzos
Clonazapam Lorazapam diazapam and others.
All SSRIs
Prozac Zoloft Celexa Paxil and the 100 others or so.
Isn't this the pharmacy just reissuing a medication so as to keep that 7
years on it with a slight chemical change.
I know that Benzos cause what is called pseudo spindles in the EEG, doesn't
matter what Benzo your on. And (all) SSRIs cause what is called Prozac eyes,
a pronounced rolling of the eyes during sleep
Mo Money Mo Money Mo Money.
I am sure there are other types of meds.
This is all I know of but it makes me go MMMMMMMM.
Mike
howdydave - 11 Jan 2006 19:10 GMT
Howdy Mike!

As I understand it, all of the cousins have slight chemical
differences.  These slight differences make for slight variations of
the molecular structures.

Some will bond better with your brain cells and others will bond better
with mine.
Elsea - 14 Jan 2006 18:46 GMT
You make a good point.  In the case of Prilosec, it recently went
generic so the drug company turned out Nexium, which is very similar to
Prilosec so they could get a name brand back on the market again for
another 7 years.
Benzodiazipines are different though.  Clonazepam worked well for my
dystonia, Zanax did nothing.  Oxazepam made me sick.  So there's
differences.
Elsea
> I would like to know something that maybe only a few really know, or maybe
> more but I sure don't.
[quoted text clipped - 13 lines]
> This is all I know of but it makes me go MMMMMMMM.
> Mike
polaris - 15 Jan 2006 14:29 GMT
Pharmaceutical companies conduct a great deal of research and development,
which is very expensive.   All the new drugs becoming available don't
simply fall from
the sky.  Seven years for a patent is very short when compared
to other industries.

Many people seem to be oblivious to the fact that economics applies to
medicine.
The industry is far too restricted by government regulations already.

Screaming that a drug should be made "affordable" doesn't reduce the cost of
producing that drug by a single penny.

Anyone who doesn't believe this should simply watch in the near future
as pharmaceutical
companies try to absorb the cost of the US prescription drug plan.
Those with epilepsy
currently receiving their drugs on special plans - if they aren't
elderly - may find
they can no longer get their drugs because pharmaceutical companies can
no longer
afford to continue those plans.

> You make a good point.  In the case of Prilosec, it recently went
> generic so the drug company turned out Nexium, which is very similar to
[quoted text clipped - 4 lines]
> differences.
> Elsea
partials - 15 Jan 2006 17:08 GMT
<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN">
<html>
<head>
 <meta content="text/html;charset=ISO-8859-1" http-equiv="Content-Type">
 <title></title>
</head>
<body bgcolor="#ffffff" text="#330033">
<blockquote cite="mid43CA5C64.8050403@intrstar.net" type="cite">Pharmaceutical
companies conduct a great deal of research and development,
 <br>
which is very expensive.&nbsp;&nbsp; All the new drugs becoming available don't
simply fall from
 <br>
the sky.&nbsp; Seven years for a patent is very short when compared
 <br>
to other industries.
 <br>
 <br>
Many people seem to be oblivious to the fact that economics applies to
medicine.
 <br>
The industry is far too restricted by government regulations already.
 <br>
 <br>
Screaming that a drug should be made "affordable" doesn't reduce the
cost of
 <br>
producing that drug by a single penny.
 <br>
</blockquote>
It was more or less ok up to this point.<br>
<blockquote cite="mid43CA5C64.8050403@intrstar.net" type="cite">Anyone
who doesn't believe this should simply watch in the near future as
pharmaceutical
 <br>
companies try to absorb the cost of the US prescription drug plan.
Those with epilepsy
 <br>
currently receiving their drugs on special plans - if they aren't
elderly - may find
 <br>
they can no longer get their drugs because pharmaceutical companies can
no longer
 <br>
afford to continue those plans.
 <br>
</blockquote>
You're joking of course?&nbsp; I don't know where you're getting that from,
but from everything that I've seen and experienced, the pharmaceutical
companies aren't out a nickel in the deal. The brunt of the cost is to
the Federal budget deficit aka the American taxpayers and to the
patients.<br>
<br>
We also got a New Year's present from the pharmaceutical companies. The
basic monthly cost of my Pfizer Neurontin just went up from $236 to
$274, or about a 16% increase. The cost of my Pfizer Dilantin went from
$38 to $42, a 31% increase for a drug whose research costs have
supposedly been paid off.. Another medication I use went up 35%. I pay
a price that's discounted from those numbers, but not all that much
lower and still higher than last year, only because of insurance that I
pay for out of my own pocket.<br>
<br>
ticked<br>
<br>
<br>
<br>
</body>
</html>
Mike Kelliher - 15 Jan 2006 20:34 GMT
Well that's all nice and good but capitalism taken to its end means that the
rich get the meds and poor and elderly don't.
The whole point of this discussion is not that having a drug for 7 years is
inappropriate but that having 10 copy cat drugs is inappropriate.
I mean really Lexapro comes out as another SSRI and claims to do the exact
same thing as Paxil, an SSRI????
How would you feel if you were buying a car and someone told you this car is
faster and better except when you took it home it was the same car you
bought 7 years prior. Except now you paid a lot more.
While I am not a chemist I do see a tremendous amount of copycat drugs where
I work.
I think there is a tremendous amout of motivation "money that is" to repeat
these drugs again and again. They lobby very strong in Congress and send a
lot salesman to all the doctors offices for a reason.
Generally the very nature of health care is altruistic. These drug companies
are not.
They are seen more like insurance companies where the bottom line is only
the dollar.

> Pharmaceutical companies conduct a great deal of research and development,
> which is very expensive.   All the new drugs becoming available don't
[quoted text clipped - 28 lines]
>> differences.
>> Elsea
polaris - 17 Jan 2006 04:16 GMT
> Well that's all nice and good but capitalism taken to its end means that the
> rich get the meds and poor and elderly don't.

Good summary of Karl Marx's definition of capitalism.

>> The whole point of this discussion is not that having a drug for 7 years is
>> inappropriate but that having 10 copy cat drugs is inappropriate.

Who gets to decide what is "appropriate" FOR THE PATIENT if not the
patient and
their doctor?  Any doctor will know that two drugs are identical, as
well as any pharmacist.

Your concern about copycat drugs is fear-mongering.

> These drug companies are not [altruistic].  They are seen more like insurance
companies where the bottom line is only the dollar.

It's good that someone is looking out for the bottom line.  Where health
care is
involved, many patients certainly are not.  Most patients simply do not know
what it costs for an office visit to their doctor.  They know how much
their co-pay
is, but not the true bill.

I had an exchange in this newsgroup a year or two ago with a man
from Canada who asked why the US didn't pass "Universal" health care so
that everyone would be assured of having their health needs met.  He told me
that he could call his neurologist and see him any time he wanted.  It
was only several
messages later that he grudgingly confided that he hadn't seen his
neurologist in 7 years,
even though he was still receiving medication under this doctor's
prescription.

Seven years!

There is much that needs to be fixed about the current state of health
care in the US.  "Universal" health
care will only lead to a rationing of health services, out-migration of
skilled health care workers, and lower
overall quality of health.

Current examples are England, Canada, and Tennessee.

> Well that's all nice and good but capitalism taken to its end means that the
> rich get the meds and poor and elderly don't.
[quoted text clipped - 14 lines]
> They are seen more like insurance companies where the bottom line is only
> the dollar.
G. - 17 Jan 2006 04:46 GMT
Ahead of Christmas, I had occasion to need another repeat of the pills
I use (mentioned in earlier post above-- my Neuro had been refilling my
Anti-seizures meds by phone since my last seizure in 1998).  My Neuro's
office  told the pharmacy, since I hadn't had need to see him in
person, that he wanted to transfer my file back to my Family Doctor who
referred me to him.

  I called my Family Doctor the next morning at 10 AM.  At 130PM (that
day) he wrote me replacement prescriptions for my Tegretol CR and
Frisium, and I had them filled at my Pharmacy that afternoon.  I picked
them up the next day..   Socialized medicine at work.   G./
gomper - 20 Jan 2006 10:46 GMT
>  Ahead of Christmas, I had occasion to need another repeat of the pills
> I use (mentioned in earlier post above-- my Neuro had been refilling my
[quoted text clipped - 7 lines]
> Frisium, and I had them filled at my Pharmacy that afternoon.  I picked
> them up the next day..   Socialized medicine at work.   G./

Pretty much the same way it will work in Norway, where we have got a
health care system that is a remnant of the social democracy we had in
our country since 1945 up to the 70's (and then from last autumn on
again). For an eight year period a conservative government would try to
privatize parts of the health care system, which would (partly) lead to
health institutions with some highly qualified personell, but
economically within reach only for the few, or those willing to take
expensive loans. Well, perhaps not all that bad, but there was an
obvious tendency. Also,  the health system makes sure that noone will
have to pay more that approx. $250/yr. The government will take care of
the rest. The system is still far from perfect, but the most part of the
 Norwegians can afford getting seriously ill, without relying on their
private insurances.
Socialized society at work.

ole k
Dave Keays - 25 Jan 2006 23:52 GMT
>>  Ahead of Christmas, I had occasion to need another repeat of the pills
>> I use (mentioned in earlier post above-- my Neuro had been refilling my
[quoted text clipped - 22 lines]
> private insurances.
> Socialized society at work.

The capitalistic society in the US helped take care of me. I got help from both
the Government and individual corporations. Getting help from the Government was
the most difficult because of all the red-tape and arrogant clerks.

I'm glad socialism helped you, but not everybody agrees with some of the other
issues.

Signature

Dave Keays

polaris - 26 Jan 2006 12:27 GMT
If the government takes care of the rest, then $250 is not the upper limit.

G, where do you think the Norwegian government gets the funds to pay for
health care?

> Also,  the health system makes sure that noone will
>> have to pay more that approx. $250/yr. The government will take care of
>> the rest.
polaris - 26 Jan 2006 12:44 GMT
I asked G, but it looks like that's gomper's quote.

Also, good to hear, G, that socialism works for you.  Many in Canada
want to see a doctor and can't.

> Socialized medicine at work.   G./

> If the government takes care of the rest, then $250 is not the upper limit.
>
> G, where do you think the Norwegian government gets the funds to pay for
> health care?
G. - 26 Jan 2006 16:24 GMT
Where do they live?  There are waiting lists in some areas (new
communities), many closer to resource development, away from major
population centres, but the system is now in about its 44th year.
There are also stresses in  the 5 major Cities where new Canadians
move to, and add to stresses on the system because of previous
Government cutbacks to balance their various budgets at the expense of
the weak or elderly.
 Also if there aren't enough residency spots when Doctors or Nurses
finish Med.School, they go to the U.S.   When they graduate they can
come back here and work at a Capped Income, or work in the U.S. for
(U.S.) Cash.   Most are staying down there. (That was from my Neuro in
1997, when he had his 3rd resident sitting-in, with our session back
then, when I saw him more often.)
 It's us Baby Boomers, here, U.S. and U.K. who will start to increase
the demand in next 10 years.  But that was predicted and should have
been planned for.  The Limits of Growth was probably one of the
earliest books on that, there are lots more now on Economics,
Globalism, that explain a lot of that.
 The new Conservative Government just elected (this week), you'd know,
have promised to fix any backlogs, waiting lists, residency spots,
medical supports, homecare, a puppy for every child and cookies and
chocolates for everyone who voted for them.  Time will tell.  As one of
the Finance Ministers said years ago, changing Supports and Government
Policy is a little like turning an Ocean Liner with a half dozen
oars...   G./
polaris - 26 Jan 2006 21:21 GMT
It sounds like you're happy with:

a doctor who writes a prescription for you without ever seeing you;

(maybe that's related to the physician shortage, do you think?)

politicians deciding the health care you should and should not receive.

By the way, the idea of corporate taxes is a myth.  Corporations don't
pay taxes.  They simply charge more for their
goods and services, and the consumer pays it for them - in addition to
what they already pay in their own individual
taxes to the government.

I'm happy that I don't live in Canada.  :)

> But that was predicted and should have
> been planned for.  The Limits of Growth was probably one of the
> earliest books on that, there are lots more now on Economics,
> Globalism, that explain a lot of that.

> Ask him how Norway pays for
> their healthcare.
>   Probably through Income and Corporate taxes like I do here.
G. - 27 Jan 2006 07:16 GMT
So am I. A course in basic economic theory would show how taxes get
collected/redistributed based on priorities that are set either by
citizens or politicians.   If you had read the other thread, you'd have
seen a post where I said I called my Family Doctor the next morning
(when the Neurologist wanted to transfer my file back to him), saw him
at 1PM, handed the Fresh Prescriptions to the Drug store at 3PM (Paper
copy) and picked them up next day.
  (The earlier neurologist was the one who admitted me to *hospital in
1993 (onset date), and 2 other times from then to 1995. To 1997 I saw
him each 1-3 months depending on level of seizure control and med.
changes, and he renewed the scripts by phone-- we have those up here--
as my doses varied but not the medication.  I saw him when I had my
*last Complex Partial seizure in 1998 and was struck by a car.)
.  He renewed my prescriptions each 100 days, direct to the pharmacy
since I didn't have further seizures (I've only posted this now about
*5 times). Then, as I hadn't had further seizures for several years,
but am still medicated for them, he transferred my file back to my
Family Doctor, who had referred me to him to start with, when the
seizures began.)

 You should ask for a shareholder's report from Exxon or another U.S.
company and see the parts about Federal taxes, Payroll taxes, etc.
paid. When you buy gas at the pumps, not only will you see  Exxon
paying taxes on their income, but there's federal tax already buried in
the Pump Price you're paying, as with clothes, food, anything you buy
or consume.
 The fact that you pay for products that others sell is how the system
works. Whether you exchange deer skins, coloured stones, or paper
money, doesn't change the fundamentals of basic economic theory,
mentioned above.. The choices that arise are merely if you let the
people you elect redistribute the money to people who need it, for
eldercare or medicare, or whether you let them build more missiles. A
lot of cash probably gets 'lost' between ordering a jet plane, and
having it delivered to a battle front. Who do you think pays those
lobbyists?   But that's getting off topic too.   G./
G. - 26 Jan 2006 16:48 GMT
It was ole's quote, who lives in Norway.  Ask him how Norway pays for
their healthcare.
 Probably through Income and Corporate taxes like I do here. G./
Ole Kvaal - 26 Jan 2006 21:15 GMT
G. skrev:
> It was ole's quote, who lives in Norway.  Ask him how Norway pays for
> their healthcare.
>   Probably through Income and Corporate taxes like I do here. G./

Yup. Although quite a few will claim the taxation level is too high, I
even pay my taxes with a smile, knowing that I am not only sort of
paying for my own welfare, but also for others'. But like I wrote in my
previous post, the system is far from perfect, lots of money disappear
on the way into over-administration etc, but on the whole, it works
pretty well.
Also, Norway is the third richest country in the world (only beaten by
Luxembourg and Qatar. That is, compared with the number of citizens.).
All this due to the rich oil resources in the North Sea. And that helps.

Signature

/\,

ole kvaal

G. - 26 Jan 2006 23:11 GMT
 And in neither of our countries does someone need to become bankrupt
if they get a surprise illness, or need healthcare. G./
Dave Keays - 27 Jan 2006 05:23 GMT
> G. skrev:
>> It was ole's quote, who lives in Norway.  Ask him how Norway pays for
[quoted text clipped - 10 lines]
> Luxembourg and Qatar. That is, compared with the number of citizens.).
> All this due to the rich oil resources in the North Sea. And that helps.

I would not feel comfortable with that system unless the society was small and
manageable. I would feel even more comfortable on a commune where I new
everybody and everybody knew me. But the tremendous diversity in America
(culture, knowledge, wealth, attitudes) make it difficult if not impossible for
me to think that my money is being spent in a way that would minimize anothers
pain. Or would it massage the politician/bureaucrat PR/ego.

I don't like to be forced to pay/provide for assistance that I'm not sure is
helpful. That is why I'm staying where I am, doing what I can, enjoying it, and
once I get back on my feet I'll be giving money to kitchens on the streets in LA.

I hope you enjoy your society as much as I'm enjoying mine!

Signature

Dave Keays

G. - 27 Jan 2006 06:31 GMT
I mentioned earlier it's been in place since about 1960 (46 years).
Probably one difference between the 2 systems (you'd have to know how
the US one is run), is the Canada one the Healthcare money is collected
at the Federal Level, then partitioned to each Province based on
population, need, current profiles and payscales of those who can
afford to pay more.   Each Province runs their own Medical System, so
long as it's within Guidelines required by the Federal Health
Department.
 Any bureaucracies then occur at *that level, and not one Big Brother
Central, as some of you seem to assume. Some provinces currently have
shorter wait times than others.  Some already provide a Pharmacare
plan, for prescriptions and rehab. appliances, that others haven't
adopted yet (most Companies provide those as taxable benefits to
employees, and have since above date).
  We've had a non-taxed Dental program at most large companies since
1974 or so.

  Our new Prime Minister has promised to give priority in his first
year to setting up improved, measurable, ElderCare, expanded Medicare
that *might (he hasn't said yet) include Prescription plans for all
Provinces, so that everyone has access to them, again managed by each
Province to Federal standards.
  The only reason that the Provinces get control of Funding and how
services are delivered, is Quebec is 70% French and insists on running
their own plans, independent but funded by Federal and Provincial tax
base. In many respects they are ahead of some provinces in benefits
they provide, in part from having a larger population base and
Corporate Head Offices who carry a higher part of the tax load. But the
balancing from the Top, allows improved care for people who happen to
live in smaller Provinces with smaller populations, so less Tax Base to
draw on.
   A further area that is planned for attention is the 5-6 Large
Metropolitan areas where new Canadians come first and whose hospitals,
transit, services, and medical needs have not been adequately funded
over the last ~15 years by a previous government (now gone), but who
eliminated a ~300 Million Dollar annual deficit.  New plans will be put
into place, without borrowing from our children, to fund what we've
been used to these last 40 years.
 That's different from other countries who print more money, as
needed, not recognizing the long term effect of having a crushing debt
their kids will inherit, or how it devalues money already in
circulation.  I just watched a TV show that said that in 2008 China
will be manufacturing Automobiles with better emission standards for
$8000 Canadian.  That's about $6400 U.S.  Which car plants will be able
to compete with that?    End rambling as I'm getting more off topic. G./
Dave Keays - 27 Jan 2006 07:50 GMT
So now I know more about the Canadian system. I used to think it was a criddle
to grave system (I think) they have in Germany.

It's good to hear it is a de-centralized system that allows for contributions
from outside the system (companies). It is much more like a "safety net" I think
society needs, and FDR set up in the US.

The next thing that I have to affirm as true or a myth is the cost of other
countries pharmaceutical care in US dollars. Basically, 70% to 80% of
pharmaceutical innovations comes from the US who has to carry the RD load
themselves. RD is a tremendous expense in drug companies. The degree of
perfection required. The series of tests required before any human consumption.
Then more testing before it is available for mass consumption. The cost of RD is
usually reflected on by stretching the pricing out to several years.

So now after an American drug company finally got a new drug on the market, many
countries will undermine their long-term pricing by selling items for a
subsidized below market price. Bottom-line; most people benefit, most carry
their share of the immediate cost of the drug, but the drug companies shoulder
the RD costs.

Signature

Dave Keays

partials - 27 Jan 2006 15:56 GMT
> So now after an American drug company finally got a new drug on the market, many
> countries will undermine their long-term pricing by selling items for a
> subsidized below market price.

The drug company is still making a profit at the negotiated price, just
not as large a profit. They wouldn't sell there at all if it was at a loss.

> Bottom-line; most people benefit, most carry
> their share of the immediate cost of the drug, but the drug companies shoulder
> the RD costs.

That has to come out of somebody's pocket and that's the US consumer in
terms of higher prices than elsewhere. Don't forget also that a lot of
the R&D is funded by government and that comes out of the US taxpayer's
pocket.
G. - 27 Jan 2006 21:56 GMT
Please try to cut and paste more accurately.
 The earlier post where you wrote this above, was an inept cut from an
earlier post, done by Dave Keays, as you noted, *quoting me*. When you
picked it up says "G said... "  the part of mine he quoted was cut out
completely, and stuff you left in was his post "so now after an
American drug company finally got a new drug to market etc". isn't my
quote.. It's the reply he did where he Included my stuff with G.wrote,
but you cut My stuff and left his reply.    I didn't write the stuff
you then replied to.     G./
 Part you posted is included below -->
G. wrote:
**************************** I'm the one living in Canada, I didn't
write below.

So now I know more about the Canadian system. I used to think it was a
criddle
to grave system (I think) they have in Germany.

It's good to hear it is a de-centralized system that allows for
contributions
from outside the system (companies). It is much more like a "safety
net" I think
society needs, and FDR set up in the US.

The next thing that I have to affirm as true or a myth is the cost of
other
countries pharmaceutical care in US dollars. Basically, 70% to 80% of
pharmaceutical innovations comes from the US who has to carry the RD
load
themselves. RD is a tremendous expense in drug companies. The degree of

perfection required. The series of tests required before any human
consumption.
Then more testing before it is available for mass consumption. The cost
of RD is
usually reflected on by stretching the pricing out to several years.

So now after an American drug company finally got a new drug on the
market, many
countries will undermine their long-term pricing by selling items for a

subsidized below market price. Bottom-line; most people benefit, most
carry
their share of the immediate cost of the drug, but the drug companies
shoulder
the RD costs.
--
Dave Keays - 28 Jan 2006 01:49 GMT
> Please try to cut and paste more accurately.
>   The earlier post where you wrote this above, was an inept cut from an
[quoted text clipped - 5 lines]
> but you cut My stuff and left his reply.    I didn't write the stuff
> you then replied to.     G./
[snip]

G.

I'm sorry I screwed-up this one.

This is not partials fault. When looking back I found that my post has the line
"G said:" without your words. I either completely cut your words out or I left
the "G. said" line.

Signature

Dave Keays

partials - 28 Jan 2006 02:00 GMT
> Please try to cut and paste more accurately.

I'm sorry about that GR and I really should have caught it and I can
assure you that it wasn't intentional. In a later post I see that Dave
is graciously attempting to accept part of the responsibility, but it
was my post and my snafu and I accept full responsibility.

Please accept my apology and let's put this behind us and get on with
the discussion. :-)
polaris - 28 Jan 2006 11:43 GMT
My last message quoted from your two most recent posts to me, both of
which were written wholly by you and contained no quotations.

The problems of quoting from nested passages have been noted already.  I
only recently joined and did not receive some of the original messages.

Thanks for the reminder.

> Please try to cut and paste more accurately.
>   The earlier post where you wrote this above, was an inept cut from an
[quoted text clipped - 43 lines]
> the RD costs.
> --
Dave Keays - 28 Jan 2006 03:57 GMT
>> So now after an American drug company finally got a new drug on the
>> market, many
>> countries will undermine their long-term pricing by selling items for a
>> subsidized below market price.

These are my arguments, not Gs. I messed-up and made it look like G was making
the statements about American drug Companies. She explained the Canadian medical
system and I responded with my understanding of the American drug companies.

Now let me go on and respond to your responses.

> The drug company is still making a profit at the negotiated price, just
> not as large a profit. They wouldn't sell there at all if it was at a loss.

The question isn't whether or not the drug companies are making a profit, but
whether or not the profit is enough to recover their RD expenses. Then there is
the effect this will have on the market. Since American companies are competing
against foreign companies with a smaller long-term costs, the American companies
would have less of market percentage.

>> Bottom-line; most people benefit, most carry
>> their share of the immediate cost of the drug, but the drug companies
[quoted text clipped - 5 lines]
> the R&D is funded by government and that comes out of the US taxpayer's
> pocket.

Yes, the US consumer prices would be one target, but I still say the drug
companies would be another.

As far as subsidized drugs. That's one issue I'm not sure of. I don't like the
government interfering in the private market, but I understand the need to help
so that a drug can get on the market. We are talking about more than just
Economic issues here, but the Libertarian in me still screams bloody murder.

Signature

Dave Keays

partials - 28 Jan 2006 16:07 GMT
 > Now let me go on and respond to your responses.

>> The drug company is still making a profit at the negotiated price, just
>> not as large a profit. They wouldn't sell there at all if it was at a loss.
>
> The question isn't whether or not the drug companies are making a profit, but
> whether or not the profit is enough to recover their RD expenses.

That's just another way of saying that they may be selling at a loss. I
give them credit for being smarter than that. Perhaps we haven't defined
our terms?

> Then there is
> the effect this will have on the market. Since American companies are competing
> against foreign companies with a smaller long-term costs, the American companies
> would have less of market percentage.

I don't understand. Are you comparing American companies selling
*brand-name* drugs against foreign companies selling *generics* or
foreign companies selling their own "brand-names*?

>>> Bottom-line; most people benefit, most carry
>>> their share of the immediate cost of the drug, but the drug companies
[quoted text clipped - 7 lines]
> Yes, the US consumer prices would be one target, but I still say the drug
> companies would be another.

But they knowingly enter these agreements. The Veterans Administration
negotiates price breaks for their hospitals. The Canadian government
negotiates price breaks. If those prices represent a loss then why do
they sell at those prices? Why not say no, this is our price?

> As far as subsidized drugs. That's one issue I'm not sure of. I don't like the
> government interfering in the private market, but I understand the need to help
> so that a drug can get on the market. We are talking about more than just
> Economic issues here, but the Libertarian in me still screams bloody murder.

Subsidies only encourage the continuation of wasteful practices if
that's what they are. They also come out of the taxpayers' pocket.
Dave Keays - 28 Jan 2006 20:14 GMT
>  > Now let me go on and respond to your responses.
>>
[quoted text clipped - 9 lines]
> give them credit for being smarter than that. Perhaps we haven't defined
> our terms?

In other parts of the post I emphasized "long-term". In essence I mean an
expenditure that is probably amortized over a period of time. For example; when
you buy a building does that only effect your profits for the first year or for
many? When comparing the amount posted on a "balance sheet" to the amount of
money going in/out of a pocket, it would result in a larger profit the first
year and a smaller profit for the rest of the amortization period.

Also, it is not unusual for a company to sell a product at a loss on one market
which covers some of the expenses and may increase "brand recognition" (PR)
thereby improving both sales and the profit in other markets.

>> Then there is
>> the effect this will have on the market. Since American companies are
[quoted text clipped - 6 lines]
> *brand-name* drugs against foreign companies selling *generics* or
> foreign companies selling their own "brand-names*?

I would think it would be both. Without the RD, the drugs wouldn't be used
safely. However, I'm not sure about international patents so I don't know where
the limits are when it comes to "brand-names vs. brand-name".

>>>> Bottom-line; most people benefit, most carry
>>>> their share of the immediate cost of the drug, but the drug companies
[quoted text clipped - 12 lines]
> negotiates price breaks. If those prices represent a loss then why do
> they sell at those prices? Why not say no, this is our price?

See above, about selling at a loss in one market.

[snip]

Signature

Dave Keays

G. - 28 Jan 2006 17:30 GMT
> So now I know more about the Canadian system. I used to think it was a criddle
> to grave system (I think) they have in Germany.
[quoted text clipped - 7 lines]
> pharmaceutical innovations comes from the US who has to carry the RD load
> themselves.

  Why would the Dollar values elsewhere help confrim above?  Most
pharmaceuticals are likely manufactured in the countries they're used.
Why would you think Italy or Germany would ship meds. around the world
from the US?   We had an earlier thread about shelf life and quality
controls affecting whether a pill is ineffective or not.  Why would I
want a pill manufactured somewhere that doesn't have same standards as
my country?
  If the Copyright or Developer of a med. was based in France, they
would get the Fees for use of the copyright, for a number of years (20?
I don't recall what standard Worldwide period is).

I'm sure Hoesch Roessel (sp?) and companies doing research in Germany,
Norway, Sweden, Italy, Canada and other countries would be surprised to
find that the US is doing '70-80% of the research in the World..

 And in most cases, discussed here a year ago, the cost of what you
pick up at the Pharmacy (if that's the Dollar basis you plan to use),
has a Dispensing Fee included in it. One survey done in Canada about 7
years ago found **that part of the Cost of a bottle of pills could vary
from around $10 for Walmart up to $14-15 at other places.  So that
would skew any comparison of eg. a $30 bottle of pills you pick up.
(Mine are 2 types at $75. and $66. for 200, plus a Dispense fee of $12
for each of the 2 bottles. My insurer pays 80% of that, mentioned
before, that becomes Taxable as Income to me.  Others have insurers who
pay Less, Seniors in some Provinces pay Nothing for their meds., and
people below a certain income level-- Subject line above-- so wouldn't
know the cost to compare with your survey.   Many of the people who'd
pay nothing don't even get a receipt, unless possibly at year-end, to
confirm that the Pharmacy didn't overbill for pills not received. )
G./

RD is a tremendous expense in drug companies. The degree of
> perfection required. The series of tests required before any human consumption.
> Then more testing before it is available for mass consumption. The cost of RD is
[quoted text clipped - 6 lines]
> the RD costs.
> Dave Keays

** The formula for the Patented Pill, before Generics are allowed,
isn't released until whatever the period is, that's first allowed to
the Drug Developer -- 10 years?  G./ )
Dave Keays - 28 Jan 2006 22:21 GMT
[snip]

>> The next thing that I have to affirm as true or a myth is the cost of other
>> countries pharmaceutical care in US dollars. Basically, 70% to 80% of
[quoted text clipped - 8 lines]
> want a pill manufactured somewhere that doesn't have same standards as
> my country?

If most medications were manufactured in the country they were used in, then why
was "reimportation" of drugs a big issue in the US a couple of years ago? Some
wanted to be able to buy American made prescription drugs off lower-cost markets
and resell them in America.

I think the standards apply to products sold so consumers in one country would
get medication that met the safety standards of that country. No matter where
the medication was produced.

>    If the Copyright or Developer of a med. was based in France, they
> would get the Fees for use of the copyright, for a number of years (20?
>  I don't recall what standard Worldwide period is).

I just plain don't know. By the way, I think it would be patented, not copyrighted.

>  I'm sure Hoesch Roessel (sp?) and companies doing research in Germany,
> Norway, Sweden, Italy, Canada and other countries would be surprised to
> find that the US is doing '70-80% of the research in the World..

The 70%-80% figure is from my memory of an article by either Thomas Sowell at
Hoover Institute or Walter Williams at CATO. Since I can't find a direct
reference. In my mind the numbers are in question but the idea is still intact.

>   And in most cases, discussed here a year ago, the cost of what you
> pick up at the Pharmacy (if that's the Dollar basis you plan to use),
[quoted text clipped - 11 lines]
> confirm that the Pharmacy didn't overbill for pills not received. )
> G./

I didn't know there was a question about whether prices were higher in the US or
in Canada. It seems to be a common theme in almost every article I've read about
the situation, no matter how they think the situation should be handled.

>  RD is a tremendous expense in drug companies. The degree of
>> perfection required. The series of tests required before any human consumption.
[quoted text clipped - 11 lines]
> isn't released until whatever the period is, that's first allowed to
> the Drug Developer -- 10 years?  G./ )

I don't know.

True, an adequate "patent time" (?) would reduce the impact of the situation but
other factors are involved.

Signature

Dave Keays

Ole Kvaal - 28 Jan 2006 19:57 GMT
Dave Keays skrev:
>> G. skrev:
>>> It was ole's quote, who lives in Norway.  Ask him how Norway pays for
[quoted text clipped - 17 lines]
> me to think that my money is being spent in a way that would minimize anothers
> pain.

I get your point very well, and I agree.

> I don't like to be forced to pay/provide for assistance that I'm not sure is
> helpful. That is why I'm staying where I am, doing what I can, enjoying it, and
> once I get back on my feet I'll be giving money to kitchens on the streets in LA.
>
> I hope you enjoy your society as much as I'm enjoying mine!

I'm sure I do! :-)

Signature

/\,

ole kvaal

Chris Lesurf - 22 Jan 2006 06:12 GMT
> There is much that needs to be fixed about the current state of health
> care in the US.  "Universal" health
> care will only lead to a rationing of health services, out-migration of
> skilled health care workers, and lower
> overall quality of health.

> Current examples are England, Canada, and Tennessee.

On what evidence do you base your sweeping generalisations ?

Chris L.

At present I am taking 4 drugs and seeing my G.P.- sometimes as frequently
as once a week, a consultant psychiatrist-once a month if necessary, a
consultant neurologist-every 6 months, a community psychiatric nurse (CPN
- varying frequencies. He's not very good but is labelled my 'key worker')
and an occupational therapist (OT-varying frequency and others have been
for a lot longer period. This is the one area where the NHS is trying to
reduce their service and not offer any OT outside hospitals).

I also see someone from each of 2 charities - a local Employment Access
Trust and a local Family Support Project which is also helping my husband
when he needs it as my carer.

Perhaps I shouldn't have reacted so strongly because I live in Scotland
not England !
Chris Lesurf - 22 Jan 2006 06:15 GMT
On 22 Jan, christal@orpheusmail.co.uk wrote:

> > There is much that needs to be fixed about the current state of health
> > care in the US.  "Universal" health
> > care will only lead to a rationing of health services, out-migration of
> > skilled health care workers, and lower
> > overall quality of health.

> > Current examples are England, Canada, and Tennessee.

> On what evidence do you base your sweeping generalisations ?

> Chris L.

> At present I am taking 4 drugs and seeing my G.P.- sometimes as frequently
> as once a week, a consultant psychiatrist-once a month if necessary, a
[quoted text clipped - 3 lines]
> for a lot longer period. This is the one area where the NHS is trying to
> reduce their service and not offer any OT outside hospitals).

> I also see someone from each of 2 charities - a local Employment Access
> Trust and a local Family Support Project which is also helping my husband
> when he needs it as my carer.

> Perhaps I shouldn't have reacted so strongly because I live in Scotland
> not England !

I forgot to say that I don't have to pay directly for any of these only
through indirect taxes.

Chris L.
Mike Kelliher - 22 Jan 2006 08:24 GMT
>> Well that's all nice and good but capitalism taken to its end means that the
>> rich get the meds and poor and elderly don't.
>
> Good summary of Karl Marx's definition of capitalism.
Do you work in our health care system with direct patient contact? The poor
get crappy care generally speaking. I am not poor nor a minority but I do
see it happen all the time.The ER is filled with the poor because they can't
afford to go see a doctor so they wait and wait and wait and end up in the
ER. That's why ERs don't make money.

Are you old yet so that your on SS? Have you been so sick as to loose your
job and insurance and be tossed aside? Our health care needs major reform.

Should we be just like Canada, no, but we should change.

>>> The whole point of this discussion is not that having a drug for 7 years
>>> is inappropriate but that having 10 copy cat drugs is inappropriate.
[quoted text clipped - 3 lines]
> their doctor?  Any doctor will know that two drugs are identical, as well
> as any pharmacist.

You are not in our health care system if you believe this. Doctors and
Pharmacists are not chemists nor do they have the time to do research. Some
doctors can't even afford to be doctors because the insurance they require
is way to high. Did you know that the FDA does not test drugs but only
reviews the testing the drug companies do for themselves. In other words
they take their word for it.

>It's good that someone is looking out for the bottom line.  Where health
>care is
[quoted text clipped - 3 lines]
>their co-pay
>is, but not the true bill.

The bottom line is our responsibility and no one else's. Having the
government, Aetna or Merck looking at my bottom line, sorry, not for me.
They have other agendas. I always try to look out for myself or to tell the
patients what they need to do to get the best care.

Do I have a negative slant on things? Yes but when it comes to me, I am
looking out for myself.
Chris Lesurf - 16 Jan 2006 06:11 GMT
That's the advantage of being British. Because my condition is permanent
and incurable, I get all my prescriptions free.

As I'm also labelled disabled for other purposes, I also get a free bus
pass from my local authority (which will now take me to anywhere in
Scotland) and reduce my train fares too. There are often reductions on all
sorts of things such as theatre tickets (which I don't claim because I
want to support our local one).

Chris L.

> Pharmaceutical companies conduct a great deal of research and development,
> which is very expensive.   All the new drugs becoming available don't
> simply fall from
> the sky.  Seven years for a patent is very short when compared
> to other industries.

> Many people seem to be oblivious to the fact that economics applies to
> medicine.
> The industry is far too restricted by government regulations already.

> Screaming that a drug should be made "affordable" doesn't reduce the cost of
> producing that drug by a single penny.

> Anyone who doesn't believe this should simply watch in the near future
> as pharmaceutical
[quoted text clipped - 5 lines]
> no longer
> afford to continue those plans.
Chris Lesurf - 16 Jan 2006 06:15 GMT
Yes, benzodiazepines are different drugs. I take clabazam (sold as
Frisium) to help me sleep and used to take diazepam as an anti-convulsant.

Chris L.

> You make a good point.  In the case of Prilosec, it recently went
> generic so the drug company turned out Nexium, which is very similar to
[quoted text clipped - 4 lines]
> differences.
> Elsea
Chris Lesurf - 16 Jan 2006 06:05 GMT
All I know about the different trade name versions of the same drug is
that even the small differences may affect you.
e.g. I know someone who reacted to the different colouring on two capsules.

Chris L.

> I would like to know something that maybe only a few really know, or maybe
> more but I sure don't.
[quoted text clipped - 13 lines]
> This is all I know of but it makes me go MMMMMMMM.
> Mike
Mike Kelliher - 28 Jan 2006 01:35 GMT
That's a given. Allergic reactions happen all the time for many reasons with
medications.
I am talking about the chemical active ingredient not the inert ingredients.
I guess I am just a cynic but I think I have a good reason to be.
There are reasons that I think I am wrong too. Like lots of SSRIs can
increase your susceptibility to seizures but a SSRI like Celexa is safer for
that purpose. Whos research are they going by and how many people were in
the study?
I wonder about that and would like to know why. Guess I will have to become
an MD in my next life.

> All I know about the different trade name versions of the same drug is
> that even the small differences may affect you.
> e.g. I know someone who reacted to the different colouring on two
> capsules.
>
> Chris L.
Mike Kelliher - 28 Jan 2006 02:00 GMT
Just looked over this site on all the chemical names of the meds and I have
realized today for the 10th time that I don't have a clue :-)
http://www.ncbi.nlm.nih.gov

> That's a given. Allergic reactions happen all the time for many reasons
> with medications.
[quoted text clipped - 14 lines]
>>
>> Chris L.

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