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Medical Forum / Diseases and Disorders / Diabetes / August 2006

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Byetta vs Symlin

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Jim - 13 Aug 2006 21:02 GMT
Does any one know if Byetta provides the same results as Symlin?  The
advantage that I see so far is that Byetta comes in a pen where Symlin
requires a syringe per dose.

Jim
calvin12@sysko.com - 14 Aug 2006 00:52 GMT
"Does any one know if Byetta provides the same results as Symlin?  The
advantage that I see so far is that Byetta comes in a pen where Symlin
requires a syringe per dose."

It does not as it works on a very different principle.  Symlin controls
glucose release from the liver, byetta prompts insulin release when
blood glucose levels get high enough and also helps with liver glucose
release.
Rick - 14 Aug 2006 11:32 GMT
I suggest a google on both byetta and symlin.  Symlin is for insulin
dependent folks where byetta is for glucose tolerance issues - non insulin
dependent.

> "Does any one know if Byetta provides the same results as Symlin?  The
> advantage that I see so far is that Byetta comes in a pen where Symlin
[quoted text clipped - 4 lines]
> blood glucose levels get high enough and also helps with liver glucose
> release.
Jenny - 15 Aug 2006 14:15 GMT
> I suggest a google on both byetta and symlin.  Symlin is for insulin
> dependent folks where byetta is for glucose tolerance issues - non insulin
> dependent.

This is an oversimplification.  I know several people who use insulin
who are getting excellent results from Byetta. Some are severely insulin
resistant. One has MODY and she has functioning beta cells but they
don't  respond correctly to incoming food.

The decider should be whether the person still has living beta cells
that are capable of producing insulin whether or not they produce enough
to control blood sugar.

--Jenny

http://www.phlaunt.com/diabetes  Diabetes Info

http://www.alt-support-diabetes.org/newlydiagnosed.htm Get Your Blood
Sugar Under Control
calvin12@sysko.com - 15 Aug 2006 14:23 GMT
"I suggest a google on both byetta and symlin.  Symlin is for insulin
dependent folks where byetta is for glucose tolerance issues - non
insulin"

If you do you will find both t1 and t2 are suggested forsymlin because
both are helped with liver glucose release.  In fact some endos are also
using byetta with t1s because of its effects with liver glucose release
and other favorable diabetic related effects that symlin doesn't
provide.
oldal4865 - 14 Aug 2006 12:17 GMT
Jim wrote in message ...
>Does any one know if Byetta provides the same results as Symlin?  The
>advantage that I see so far is that Byetta comes in a pen where Symlin
>requires a syringe per dose.
>
>Jim

  Both tend to suppress appetite.   Both tend to slow the digestion of food
(to give whatever insulin we have a fighting chance).    However,  their
mechanisms of operation are different.

In general,   if you are still making insulin,   Byetta is the favored drug.

If you are making little or none,  Symlin is the favored drug.

However,  Symlin and Byetta were part of one of the "hot" symposia at the
last ADA Scientific Conference in D.C.   As the docs' experience increases,
we're going to see what off-label fiddling can produce.    (mixing and
matching)

My friend's sister worked on Byetta for a while  (since quit and moved)
There was a bit of controversy over trying to get Byetta through the FDA as
a prescription weight loss med.    AIUI,  not enough Company resources to
register for both applications.    It's going to be interesting to see what
the docs do;   they can go off-label as they wish.

Regards
 Old Al
Paul_B - 14 Aug 2006 15:02 GMT
> Does any one know if Byetta provides the same results as Symlin?  The
> advantage that I see so far is that Byetta comes in a pen where Symlin
> requires a syringe per dose.
>
> Jim

Also, the Symlin pen is in process. It should be just a matter of
time.

p.
Jim - 14 Aug 2006 17:19 GMT
Unfortunately, there is no target date for a pen release and its' in the
initial steps of discussion on the availability in a pen version - this
information was given to my the manufaturer technical group.  I was sure
hoping that a release was soon coming.

Jim

>> Does any one know if Byetta provides the same results as Symlin?  The
>> advantage that I see so far is that Byetta comes in a pen where Symlin
[quoted text clipped - 6 lines]
>
> p.
 
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