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Medical Forum / Diseases and Disorders / Diabetes / April 2006

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Experiment reverses T1 in mice

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Robert Miles - 21 Apr 2006 15:58 GMT
Some news on an experiment that reversed T1 in mice:

http://www.healthscout.com/news/322/532232/main.html
Nico Kadel-Garcia - 22 Apr 2006 12:58 GMT
> Some news on an experiment that reversed T1 in mice:
>
> http://www.healthscout.com/news/322/532232/main.html

Interesting! We've seen several studies in the last 5 years, including Dr.
Faustman's work at MGH and some work at the University of West Virginia,
where the auto-immune problem of Type 1 was successfully treated and the
animals seemed to generate new insulin-producing cells all on their own,
probably from adult stem cells.

So it seems nice to see that there are other combinations of drugs that can
produce baguely similar results, at least in the lab.
willbill - 25 Apr 2006 07:47 GMT
>>Some news on an experiment that reversed T1 in mice:
>>
>>http://www.healthscout.com/news/322/532232/main.html

> Interesting!

i agree

but i'm not holding my breath on it happening
with t1 humans in "a few years"

for others, it's a 3 part write-up

it also, in part 1, mentions that type-1 is
only 5% of the diabetic population in the USA
(actually the "ref" appears to be to both the
 world as well as the USA)

something i've been saying for several years here

which sometimes has generated heated rebuttal from
a few others here (on m.h.d., where i usually post)

of course, what that means is that us type-1 diabetics
use maybe 2 percent, or at most 3 percent, of all
insulin sold in the USA.  and that the type-1 kids
use maybe 1 percent

<start soapbox>

so the big pharma insulin companies have NO incentive
to provide insulin that is useful for type-1 diabetics

all that counts in the now is the bottom line:
money, money, money (i.e. profits, profits, profits)

the type-2s rule when it comes to the insulin
that is offered in the USA

that's always been true, but that didn't matter
when all we had was real beef insulin and real
pork insulin.  now that we have synthetic insulin
(and especially the weird analogs), it now matters
bigtime for some of the t1 set

and inhaled insulin is only going to make it worse
for us type-1 diabetics (i.e. shrink the sales of
injectable insulin that is useful to type-1s)

the recent discontinuation of human-UL and human-L
(by Lilly) is my proof

<end soapbox>

the one good thing that has happened for t1s
this past 20 years is the competition for blood
glucose meters.  and continuous monitoring is
now available and may become a real (cost wise)
option in the next few years, see:
http://www.washingtonpost.com/wp-dyn/content/article/2006/04/22/AR2006042201354.
html?sub=AR


bill t1 since '57, ex 8-yr pumper, beef-L 1x, simple MDI

> We've seen several studies in the last 5 years, including Dr.
> Faustman's work at MGH and some work at the University of West Virginia,
> where the auto-immune problem of Type 1 was successfully treated and the
> animals seemed to generate new insulin-producing cells all on their own,
> probably from adult stem cells.
 
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