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Medical Forum / Diseases and Disorders / Diabetes / May 2008MOT: HbA1c = 4.9!
Heck - no wonder I've been getting hypos. I need to drop the Lantus again. I've already gone down from 52u per day to 34 - now I've dropped to 30 - all in 4.5 months after starting to take Xenical. My cholesterol is also very low - 1.9. My weight has dropped 10kg (about 1.5 stone) since I started the Xenical. I asked my DSN yesterday about Byetta, but though she's heard of it there doesn't seem to be much awareness of it. Even though I'm doing well on my present meds I would like to drop the insulin altogether and get a hypo -free life back, and it seems I can only do that on Byetta. EN >Heck - no wonder I've been getting hypos. I need to drop the Lantus >again. I've already gone down from 52u per day to 34 - now I've [quoted text clipped - 10 lines] > >EN The A1c is great (pity you hypoed to achieve it); not so sure about the cholesterol. What level would your doc be happy with? Is that weight drop good or too much? I understand that the prime purpose of the Xenical is weight loss; have you achieved your goal? Will you be stopping it when you do? Did the Xenical affect BG's in either direction? Cheers, Alan, T2, Australia. d&e, metformin 1500mg, ezetrol 10mg Everything in Moderation - Except Laughter. -- http://loraldiabetes.blogspot.com Latest:What to Eat Until You Get Your Meter. Angkor Wat http://loraltravel.blogspot.com > On Wed, 21 May 2008 04:35:55 -0700 (PDT), Erica Nurney > [quoted text clipped - 17 lines] > sure about the cholesterol. What level would your doc be > happy with? The DSN didn't seem too worried about the cholesterol, but realising it is a vital fatty acid, I do wonder if it can actually be *too* low. > Is that weight drop good or too much? I understand that the > prime purpose of the Xenical is weight loss; have you > achieved your goal? Will you be stopping it when you do? The weight loss is ideal given the 4.5 month period. It has made me decrease the fat in my diet, mainly because I would rather be without the interesting side effects (if you thought Mefartin causes interesting flatulent effects, you haven't tried Xenical). However, maybe the reduced fat absorption has also reduced my cholesterol - perhaps I should ask the clinicians if I need the statins? > Did the Xenical affect BG's in either direction? As I said in an earlier post on the subject, Xenical combined with a reduced fat intake, caused a sudden drop in my BGs and I have been struggling with hypos ever since. I've yet to have a major incident, as I'm fairly hypo aware, but a couple of night time ones left me staggering down the stairs with my vision blurred and barely able to stab myself for a blood test - 2.1 was the lowest. I do get the feeling that my hypo awareness is diminishing, worryingly. EN > Cheers, Alan, T2, Australia. > d&e, metformin 1500mg, ezetrol 10mg [quoted text clipped - 3 lines] > > Angkor Wathttp://loraltravel.blogspot.com >> <j_peasemold_gruntfutt...@hotmail.com> wrote: >> >Heck - no wonder I've been getting hypos. I need to drop the Lantus [quoted text clipped - 43 lines] > >EN It would seem time to review ALL of your meds. I didn't recall that earlier post. With that cholesterol level I'm darned if I can see any logical need for statins or any other cholesterol-lowering medication. What is the trigs/LDL/HDL breakout? Is it possible Xenical also interacts with the statins similarly to it's interaction with BG reducers? If you had to reduce fats, did you increase any other macronutrients or, like I did during my weight loss phase, have you reduced everything? Cheers, Alan, T2, Australia. d&e, metformin 1500mg, ezetrol 10mg Everything in Moderation - Except Laughter. -- http://loraldiabetes.blogspot.com Latest:What to Eat Until You Get Your Meter. Angkor Wat http://loraltravel.blogspot.com > Heck - no wonder I've been getting hypos. I need to drop the Lantus > again. I've already gone down from 52u per day to 34 - now I've [quoted text clipped - 10 lines] > > EN hmmmmmmmm are you taking a statin med for your Cholesterol? that number is VERY low........i'm not sure i would be too happy about it make an appt with the DSN again and TELL HER you want Byetta, please, because you want to get away from the hypos on insulin..............it is possible that you may have to stay on a low dose of insulin as some other type 2's on byetta have done stay on the 5mcg dose of byetta until you are totally comfortable with it, and move to the 10mcg dose later (they used to put you on 5mcg for the first month only, and others are finding that they do better on 5mcg for 2 or 3 months before they move to the 10 mcg pen) good luck!  Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html > > Heck - no wonder I've been getting hypos. I need to drop the Lantus > > again. I've already gone down from 52u per day to 34 - now I've [quoted text clipped - 23 lines] > the first month only, and others are finding that they do better on 5mcg > for 2 or 3 months before they move to the 10 mcg pen) I do get the feeling that if I demanded, or even politely requested, that I go on Byetta I feel I will be given the brush-off. The DSN said that trials weren't complete in the UK - I'm not sure if this is true or not. We do have a GP in the surgery who specialises in DM and his answer to my request was that my previous high HbA1c prior to going on insulin was about 9, therefore my beta cells were shot and Byetta wouldn't help. However, I have since learned that Byetta can help regenerate knackered beta cells. As far as I can see there is no financial reason not to put me on Byetta, as I'm sure the cost of my insulin must be comparable, if not considerably more. Many thanks for your advice and encouragement. EN > good luck! > > -- > kate > type 1 since 1987www.diabetic-talk.orghttp://www.diabetes-support.org.uk/newly%20diagnosed.html >I do get the feeling that if I demanded, or even politely requested, >that I go on Byetta I feel I will be given the brush-off. The DSN said >that trials weren't complete in the UK - I'm not sure if this is true >or not. Not - it's actually OK with NICE - but many PCTs are refusing to prescribe it. Suffolk, where I am, is one such; the local endo is going ballistic on a regular basis to no avail. >We do have a GP in the surgery who specialises in DM and his answer to >my request was that my previous high HbA1c prior to going on insulin >was about 9, therefore my beta cells were shot and Byetta wouldn't >help. This may be bollocks anyway - with that level of weight loss, you may well have brought your IR down enough so your beta cells can cope, somewhat anyway. Byetta sorts out any signalling issues there might be between your gut and your beta cells, so might be worth trying if you have any beta cell production at all. Does the doc intend to keep you on insulin full-time? I'm managing fine on D&E with an A1c at dx of 10.3 - unless there's reason to believe that you should be on it, sounds to me like you could lower your insulin freely? I'd be panicking about that cholesterol level, BTW. The optimum is a U-curve; lifespan is reduced just as much on the low side as the high side, from nasties like violent death and suicide. Be very interesting to know whether the Xenical is stripping out stuff you actually need. How close are you to goal? Could that be on the way out too? Nicky. T2 dx 05/04 + underactive thyroid D&E, 100ug thyroxine Last A1c 5.6% BMI 25 >>We do have a GP in the surgery who specialises in DM and his answer to >>my request was that my previous high HbA1c prior to going on insulin [quoted text clipped - 6 lines] > between your gut and your beta cells, so might be worth trying if you > have any beta cell production at all. Woah? Signalling issues between gut and beta cells... could well be one of my problems. Since I definitely have beta cell production but never at the right times, am now pretty slim and adding more metformin has done more harm than good... (as I understand it, metformin reduces both insulin resistance AND insulin overproduction, am I correct in this? So if one has no more insulin resistance to knock down, then adding more metformin to someone with "normal" or "slightly low" levels of insulin production would logically seem to be counterproductive... although I must have certainly had levels of insulin resistance at diagnosis, metformin certainly did me some serious good then.) And yes, I'm now struggling to keep my average test figure down in single figures, nowhere near as good as a couple of years ago. Except that about once every couple of weeks I wake up with a "normal" test, like a 5.9 or something, which is in fact totally incongruous given that most of my tests these days are landing between 8 and 13-ish. Sounds like maybe I ought to see if I can persuade someone to try me on Byetta... Jonathan. >Signalling issues between gut and beta cells... could well be one of my >problems. Since I definitely have beta cell production but never at the [quoted text clipped - 6 lines] >insulin resistance at diagnosis, metformin certainly did me some serious >good then.) Not quite. Metformin does two things, as I understand it. Firstly it reduces insulin resistance by activating a pathway into cells that allows glucose to get in without insulin's action - almost the same action as when the muscle's exercised. Then it calms down the production of glucose and related sugars by the liver. It doesn't act directly on insulin levels itself, except that your beta cells would be pumping out insulin to counteract an overenthusiastic liver or high IR; adding metformin should actually REDUCE your insulin production related to that fault. >And yes, I'm now struggling to keep my average test figure down in single >figures, nowhere near as good as a couple of years ago. Except that about [quoted text clipped - 4 lines] >Sounds like maybe I ought to see if I can persuade someone to try me on >Byetta... Or Januvia, which does the opposite job - instead of giving you a synthetic gut hormone, as Byetta does, Januvia stops your body clearing out the stuff you produce too quickly. It's a pill instead of an injection. Which, if either of them, work, depends on what exactly is going wrong with your body - and you certainly don't fit the standard T2 patterns. Would be worth seeing if you could get your hands on them... or a genetics check for MODY, LADA, etc... Some Mody variants do astonishingly well on tiny doses of insulin, do you read Jenny's blog? http://diabetesupdate.blogspot.com/ Nicky. > Signalling issues between gut and beta cells... could well be one of my > problems. Since I definitely have beta cell production but never at the > right times, am now pretty slim and adding more metformin has done more harm > than good... (as I understand it, metformin reduces both insulin resistance I'm in the same situation - upping the dose on the metformin either has no effect at all or actually increases my BG readings. And a 1-hour brisk walk with the dogs doesn't seem to drop my BG at all - it's generally higher afterwards than before. > And yes, I'm now struggling to keep my average test figure down in single > figures, nowhere near as good as a couple of years ago. Except that about Sounds *just* like me. I was in Gliclazide for 2 years with very good numbers until the last 2 months or so when the number started to climb into double figures. 2 months of metformin doesn't seem to have reversed the trend much. Phil SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' >> Signalling issues between gut and beta cells... could well be one of my >> problems. Since I definitely have beta cell production but never at the [quoted text clipped - 17 lines] > > Phil byetta? or a low dose of Lantus at bedtime? Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html >> And a 1-hour brisk walk with the dogs doesn't seem to drop my BG at all >> - it's generally higher afterwards than before. [quoted text clipped - 9 lines] > > byetta? or a low dose of Lantus at bedtime? Indeed. I'll do my A1C bloodtest at the end of this week and go to see the quack sometime late next week. We shall see. Phil SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' >>> 2 months of metformin doesn't seem to have reversed the trend much. >> byetta? or a low dose of Lantus at bedtime? [quoted text clipped - 5 lines] > > Phil good luck ! ! Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html >>> And a 1-hour brisk walk with the dogs doesn't seem to drop my BG at >>> all - it's generally higher afterwards than before. [quoted text clipped - 15 lines] > > We shall see. What is your weight like and blood pressure? With low cholesterol you don't exactly fit a type 2 mould. >> Indeed. I'll do my A1C bloodtest at the end of this week and go to see >> the quack sometime late next week. [quoted text clipped - 3 lines] > What is your weight like and blood pressure? With low cholesterol you don't > exactly fit a type 2 mould. My BMI (for what it's worth) is firmly in the 'ideal' range - I'm 6 ft tall and weigh 13 stone. My blood pressure is 120/80 when tested in non-stressful situations (I have a BP tester at home). Which is why I don't take the statins or blood pressure medication that was given me early on - taking them made me feel really really ill. Even my triglicerides are at the normal non-diabetic levels (or were 6 months ago). So no - I don't exactly fit the usual profile. But my mother (and her brother) are both T2 so I guess that's where I got it! Phil SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' >>> Indeed. I'll do my A1C bloodtest at the end of this week and go to see >>> the quack sometime late next week. [quoted text clipped - 15 lines] > > Phil Phil, have you read up about MODY? you have the classic 'profile' of a MODY type 2 http://www.phlaunt.com/diabetes/14047009.php Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html >> My BMI (for what it's worth) is firmly in the 'ideal' range - I'm 6 ft >> tall and weigh 13 stone. My blood pressure is 120/80 when tested in [quoted text clipped - 6 lines] >> So no - I don't exactly fit the usual profile. But my mother (and her >> brother) are both T2 so I guess that's where I got it! > Phil, have you read up about MODY? Some bits - but not in great depth. And since I was on a sulph drug at the time (Gliclazide) I didn't take it any further. I only stopped the gliclazide when it started being ineffective even at 160mg doses. > you have the classic 'profile' of a MODY type 2 And looking at the Wikipedia page on it I have other parts (very large birth weight - or at least I would have been big if I'd gone full-term but I was born before RH+ shots were available and my 3 older brothers had nicely prepped my mothers blood with antibodies against mine! As a consequence I was born several weeks early by c-section and spent my first 6 weeks in an incubator..) It would also explain why (at the moment) I'm feeling like I'm having a hypo when my BG reading is 6.8! I'll mention it to the doctor and see if I can get her to put me down for a test for it. Phil. SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' >>> My BMI (for what it's worth) is firmly in the 'ideal' range - I'm 6 ft >>> tall and weigh 13 stone. My blood pressure is 120/80 when tested in [quoted text clipped - 31 lines] > > Phil. Phil, what meds do you take if you are off the sulf? typically insulin is the next step for a MODY to get their bg under control if you go to insulin DO NOT let them give you that MixTURD cra*, insist on a proper basal (background) insulin such as Lantus or Levemir and a proper bolus insulin such as Humalog or Novorapid sometimes the Dr's insist on MixTURD, so you have to build up a record over a month or so to show them that it's forcing you to eat to feed the insulin, and then they will put you on proper basal/bolus Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html > Phil, what meds do you take if you are off the sulf? typically insulin > is the next step for a MODY to get their bg under control Metformin. Which doesn't seem to be doing the trick.. > if you go to insulin DO NOT let them give you that MixTURD cra*, insist > on a proper basal (background) insulin such as Lantus or Levemir and a > proper bolus insulin such as Humalog or Novorapid Will do. Phil SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' >> Phil, what meds do you take if you are off the sulf? typically insulin >> is the next step for a MODY to get their bg under control [quoted text clipped - 8 lines] > > Phil no, metformin does nothing for a MODY diabetic they need insulin please see your Dr soon Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html >> Phil, what meds do you take if you are off the sulf? typically insulin >> is the next step for a MODY to get their bg under control > > Metformin. Which doesn't seem to be doing the trick.. http://www.phlaunt.com/diabetes/14047009.php >> Phil, what meds do you take if you are off the sulf? typically insulin >> is the next step for a MODY to get their bg under control > >Metformin. Which doesn't seem to be doing the trick.. Yes you don't seem to have many indicators of insulin resistance so it's presumably the production side that's buggered (technical term) >> if you go to insulin DO NOT let them give you that MixTURD cra*, insist >> on a proper basal (background) insulin such as Lantus or Levemir and a >> proper bolus insulin such as Humalog or Novorapid > >Will do. You'll be lucky, you might first have to prove that mixturd doesn't work before they let you use NPH <sigh> Have a look round here http://www.projects.ex.ac.uk/diabetesgenes/index.htm >> > Heck - no wonder I've been getting hypos. I need to drop the Lantus >> > again. I've already gone down from 52u per day to 34 - now I've [quoted text clipped - 40 lines] > >Many thanks for your advice and encouragement. Unless the rules have changed (and they may well have done, the only good thing about NICE is that they reverse their decisions every so often) Byetta is only an option if you have "unacceptable" HbA1c after being on at least two medications. 4.9 is NOT unacceptable. Therefore you lose. :( Try 8.9 and you may be in with a chance. > On Wed, 21 May 2008 08:06:09 -0700 (PDT), Erica Nurney > [quoted text clipped - 52 lines] > > Try 8.9 and you may be in with a chance. It's not just about my HbA1c though, it's about losing weight, not having hypos anymore - quality of life issues. If economics is the problem, I could look on BNF55 and get an approximate cost comparison - I'll bet there is little difference and Byetta may well be cheaper. The problem is, if the PCT sees just the absolute number for Byetta - £68 per pen - they probably will run away in horror. How can I convince the medicos of my need to at least try Byetta, without undermining their professional sensibilities and offending their accountants? EN On 22 May, 08:04, Erica Nurney <j_peasemold_gruntfutt...@hotmail.com> wrote: > > On Wed, 21 May 2008 08:06:09 -0700 (PDT), Erica Nurney > [quoted text clipped - 62 lines] > undermining their professional sensibilities and offending their > accountants? Just did some sums based on my current medications and prices from BNF55. Lantus cost £23 pm, Novorapid cost £35 pm, Xenical cost £33 pm, total cost of medications which could be replaced by Byetta = £91 pcm. A single pen of Byetta, lasting for 30 days, costs £68. Even if I continue with half of my present Lantus dose, that's still only £80 pm, a full £11 pm cheaper than my present regime. That's not all - I currently use about 100 test strips a month - that could easily be reduced by a half, saving an additional £14 pm. I also use 120 needles a month, that would be halved saving a further £6 pm. In total, using Byetta instead of my existing regime would save the NHS £31 pm, or £372 pa. I would hopefully lose weight, further reducing my demands on the NHS. Some of my blood pressure medications, my statins and other medications I take as a result of my obesity (ranitidine) could be reduced or dispensed with altogether, possibly saving another £10 pm or more.. I know all this sounds just fine and dandy, but I'm not naive and I do realise that Byetta might not suit me, I might not lose weight, I might not be able to tolerate the side-effects, and why should I expect the NHS to make it easy for me to lose weight? By the way, despite my jokey and apparently female name, I am male, and 61 yo. EN > EN >In total, using Byetta instead of my existing regime would save the >NHS £31 pm, or £372 pa. I would hopefully lose weight, further >reducing my demands on the NHS. Some of my blood pressure >medications, my statins and other medications I take as a result of my >obesity (ranitidine) could be reduced or dispensed with altogether, >possibly saving another £10 pm or more.. That kind of set of figures is exactly what our local chief endo has been waving at the PCT for months now. They're not budging :( But good luck, I hope that makes you more, not less, determined... maybe more creative, as you can go outside the system! Nicky. T2 dx 05/04 + underactive thyroid D&E, 100ug thyroxine Last A1c 5.6% BMI 25 >>In total, using Byetta instead of my existing regime would save the >>NHS £31 pm, or £372 pa. I would hopefully lose weight, further [quoted text clipped - 7 lines] >good luck, I hope that makes you more, not less, determined... maybe >more creative, as you can go outside the system! Yes it's worth beating them around the head with as long as you don't expect a sensible decision at the end of the day. I'm currently fuming (again), apparently my blood tests consisted only of fbc, liver and kidney function and total cholesterol. I had to persuade the phlebotomist to add back in the A1c and full lipid panel with some nifty talking, hope I didn't lose her her job! All to save a few pennies, well bollocks if I have to starve for 12 - 14 hours I want something worthwhile to come of it. I feel another letter to my GP coming on, illustrated with graphs. But at the end of the day she's only actink unter orders . . . >>> In total, using Byetta instead of my existing regime would save the >>> NHS £31 pm, or £372 pa. I would hopefully lose weight, further [quoted text clipped - 19 lines] > I feel another letter to my GP coming on, illustrated with graphs. But > at the end of the day she's only actink unter orders . . . ve hav vays yu no RodS > On Thu, 22 May 2008 13:16:08 +0100, Nicky <ukc802466929@btconnect.com> > >On Thu, 22 May 2008 05:11:05 -0700 (PDT), Erica Nurney > >>In total, using Byetta instead of my existing regime would save the > >>NHS £31 pm, or £372 pa. I would hopefully lose weight, further [quoted text clipped - 20 lines] > I feel another letter to my GP coming on, illustrated with graphs. But > at the end of the day she's only actink unter orders . . . That totally sucks. Too many people on this side of the pond are crying, "Oh! I should have free health care." They don't realize the cost of 'free', like you blokes do. If I want a complete, comprehesive blood test, my Diabetician or Serologist does it. Same with other tests by any of my medicos. Maybe Medicare picks up part of it, maybe not. Maybe my (premium paid by me) PPO picks up part of the balance, maybe not. I'll get billed for whatever wasn't picked up. The cheque is in the mail within ten days. SignatureNick. Support severely wounded and disabled Veterans and their families! I've known US vets who served as far back as the Spanish American War. They are all my heroes! Thank a Veteran and Support Our Troops. You are not forgotten. Thanks ! ! ~Semper Fi~ >> On Thu, 22 May 2008 13:16:08 +0100, Nicky <ukc802466929@btconnect.com> >> >On Thu, 22 May 2008 05:11:05 -0700 (PDT), Erica Nurney [quoted text clipped - 27 lines] >"Oh! I should have free health care." They don't realize the cost of >'free', like you blokes do. Only for certain values of free <G> >If I want a complete, comprehesive blood test, my Diabetician or Serologist >does it. Same with other tests by any of my medicos. Maybe Medicare picks >up part of it, maybe not. Maybe my (premium paid by me) PPO picks up part >of the balance, maybe not. I'll get billed for whatever wasn't picked up. >The cheque is in the mail within ten days. Yes we can get no end of stuff done provided we pay privately BUT there have been cases of patients going private for one thing and then being rejected by the NHS for other stuff. With horrible irony I was just watching a TV History documentary, do you realise that we only just finished paying the US back for winning the war for us in 2006? And we NEARLY didn't get the NHS or any of the other "benefits" which are currently being eroded because you guys thought it was a bit Communist and wouldn't allow us to have enough money left over to set it up? The real reason it's failing IMO is that it was a Ponzi scheme (same with pensions) which relied on an increasing population paying in and a decreasing population collecting. This has now been reversed. Plus of course ever increasing amounts of funds are going to Deputy Chief Assistant Undermanagers rather than medical professionals. And much of the rest goes in supporting the profits of huge multinational pharma manufacturers. What I want to know is, where did the vast fortunes made from closing down hospitals and selling them as prime building plots end up? > On 23 May 2008 08:31:57 GMT, Nick Cramer <n_cramerSPAM@pacbell.net> > >> On Thu, 22 May 2008 13:16:08 +0100, Nicky <ukc802466929@btconnect.com> [quoted text clipped - 8 lines] > Communist and wouldn't allow us to have enough money left over to set > it up? Oh, sure! Blame me, why dontcha! ;-D > The real reason it's failing IMO is that it was a Ponzi scheme (same > with pensions) which relied on an increasing population paying in and [quoted text clipped - 5 lines] > made from closing down hospitals and selling them as prime building > plots end up? Over here, Social Security (which I paid into from 1947 to 1998) seems to have turned out to be the same. Plus, the US Congress has constantly raided it to put money into the 'General Fund' to pay for all their pork-barrel spending. And, as usual, the bureaucrats take their lion's share off the top. 'Twas ever thus. ;-( SignatureNick. Support severely wounded and disabled Veterans and their families! I've known US vets who served as far back as the Spanish American War. They are all my heroes! Thank a Veteran and Support Our Troops. You are not forgotten. Thanks ! ! ~Semper Fi~ >> On 23 May 2008 08:31:57 GMT, Nick Cramer <n_cramerSPAM@pacbell.net> >> >> On Thu, 22 May 2008 13:16:08 +0100, Nicky <ukc802466929@btconnect.com> [quoted text clipped - 10 lines] > >Oh, sure! Blame me, why dontcha! ;-D Yes perhaps I should have made a clearer distinction between the American People and your Government. (Much the same here, and for that matter probably in all countries) >> The real reason it's failing IMO is that it was a Ponzi scheme (same >> with pensions) which relied on an increasing population paying in and [quoted text clipped - 11 lines] >spending. And, as usual, the bureaucrats take their lion's share off the >top. 'Twas ever thus. ;-( Yup you got it. :( Erika It makes complete sense that your insulin is being reduced as you lose weight. Insulin is completely adaptable and you can adjust your own as you see fit and feel confident with. The amount you have already reduced it seems high to you but is actually quite reasonable. Perhaps you should think about a time when your insulin was at it's optimum i.e. when it perfectly balanced your weight and now calculate your new weight, factor in reduction in resistance and minus a bit on that. Adjust down 2u and wait 3 days... adjust down if necessary. Why do you need to go downstairs in the night for a hypo? I keep my test kit on the bedside table... with a pack of glucose tabs and a pack of 2 Weightwatchers biscuits (not becos they're WW, but becos they're handily packaged in 2s which come out around 14/15 g carbs - perfect for a hypo!). Of course if you can get Byetta none of that applies... but insulin is livable with if you have to and if your pancreas is worn out then I am afraid you're stuck with it! Patti Hba1c 5.5 On Levemir and Novorapid + meds for BP and thyroid Join us at http://www.diabetes-support.org.uk "The friendly forum!" >>> Heck - no wonder I've been getting hypos. I need to drop the Lantus >>> again. I've already gone down from 52u per day to 34 - now I've [quoted text clipped - 44 lines] >> kate >> type 1 since 1987www.diabetic-talk.orghttp://www.diabetes-support.org.uk/newly%20diagnosed.html oh freak......... trials????????????? byetta is FULLY approved in the UK byetta is used WITH insulin in the USA byetta may stimulate beta cells, but without a c-peptide test (oh, if you are on insulin the c-peptide test will be wrong) but add a pro-insulin and (brain bubble.......... it measures total insulin on board) you can determine if you have remaining beta cells function byetta PROMOTES WEIGHT LOSS and THAT is why you want to be on it! as for the Chol #'s, are you taking a statin med to lower Chol??? some schools of thought believe that too low Chol levels might cause Parkinson's disease............... there is NO evidence that getting your Chol below 4.0 is beneficial to you............. right now, the medics seem to think 'lower is better'..................HOW LOW is my question............ my last Chol was 3.65 and i did NOT like that, so i took my statin med every other day, contrary to Dr's orders......... my current Chol is 4.43 so obviously i can't go to a half dose, but perhaps a full dose on day 1 and a 1/2 dose on day 2 will keep me in the 4% range Signaturekate type 1 since 1987 www.diabetic-talk.org http://www.diabetes-support.org.uk/newly%20diagnosed.html > hmmmmmmmm are you taking a statin med for your Cholesterol? that number > is VERY low........i'm not sure i would be too happy about it My normal reading (pre-diabetes) for cholesterol was 1.6. And was that for all of the tests I took.. My father is the same - so thats one of the few *good* things I got in my genetic lottery.. And my BG readings are *still* in the 6-9[1] range even when moving my metformin dose up to 2000mg :-( Time to go back to the doctor again - I'll have a A1C test before just to give her something to base it on. Phil. [1] And in one case 12.9 - but that was after I foolishly cooked myself some nice fried potatoes with lunch. I forgot the rules and did myself a pre-diabetes sized portion.. SignaturePhil Launchbury, IT PHB 'I'm training the bats that live in my cube to juggle mushrooms' |
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