>>> http://news.bbc.co.uk/1/hi/health/7349980.stm
>>>
[quoted text clipped - 15 lines]
> there have been lots of reports in the past 5 years stating the same
> thing this article did
I gather that the general consensus is that in moderate doses,as well as
in cases where there are deficiencies in the diet, they do no harm,
while in large doses, as mentioned in the study, they can do harm in the
medium to long term.
The way I heard the interview while driving round this morning & again
just now, both sides were agreed that normal, over the counter one-a-day
tablets are harmless, even if they don't help much, whereas the mega
dose tablets need to be taken with care, if at all.
As my diet is forced by my work to be both irregular & not contain a
great amount of fresh food, I take a one-a-day. It's not ideal, but it's
the way I need to do it to pay the bills.

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John.
Tiger_Lily - 16 Apr 2008 19:49 GMT
>>>> http://news.bbc.co.uk/1/hi/health/7349980.stm
>>>>
[quoted text clipped - 29 lines]
> great amount of fresh food, I take a one-a-day. It's not ideal, but it's
> the way I need to do it to pay the bills.
oh, definitely.......... the studies were done on larger doses of one
item ......
Bernard Peek - 16 Apr 2008 20:32 GMT
> I gather that the general consensus is that in moderate doses,as well as
> in cases where there are deficiencies in the diet, they do no harm,
> while in large doses, as mentioned in the study, they can do harm in the
> medium to long term.
Like every other medicine, vitamins will have side-effects for some
people. An overdose is likely to be harmful, and some vitamins are very
toxic in doses not much larger than the therapeutic dose.
There's also a possibility that vitamins may have harmful effects even
in the dosages that are necessary for health. There's no reason why a
medicine can't have harmful effects on one part of the metabolism while
having beneficial effects on a different part. We are now getting so
good at detecting very rare side-effects. If Herr Bayer proposed using
his new-fangled preparation "Aspirin" a a pain-killer it would probably
not pass current safety tests. To put that into perspective, Aspirin had
been in widespread use for a century before it was linked with Reyes
Syndrome.

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Nicky - 17 Apr 2008 12:38 GMT
>The way I heard the interview while driving round this morning & again
>just now, both sides were agreed that normal, over the counter one-a-day
>tablets are harmless, even if they don't help much, whereas the mega
>dose tablets need to be taken with care, if at all.
Mega dose tabs certainly look damn dangerous - but I think there's
enough evidence to say that synthetic versions of common vits may
cause more harm than good. Vit A springs to mind, where the natural
form is all right-handed (I think, might be a leftie!) whereas the
synthetic stuff is a mix. The wrong sort actually blocks takeup of the
right sort.
Personally, I'd rather concentrate on a balanced diet. I take
glucosamine and fish oil, and that's me lot. I am contemplating a vit
D supplement for next winter, though - but the mechanism of that is
different; you take d3 and it's changed to the active form in the
liver and kidneys.
Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6% BMI 25
John Williamson - 17 Apr 2008 14:13 GMT
> Personally, I'd rather concentrate on a balanced diet. I take
> glucosamine and fish oil, and that's me lot. I am contemplating a vit
> D supplement for next winter, though - but the mechanism of that is
> different; you take d3 and it's changed to the active form in the
> liver and kidneys.
I'd love to be able to concentrate on a balanced diet. Unfortunately,
the way I earn my living precludes it to a large extent, & I'm too old
to retrain for another job with enough income to pay the bills. When I'm
home, I can eat well very easily, when I'm touring, it's nigh on impossible.
I didn't know Vitamin A was chiral, though, I'll have to look into it,
but I should get enough of the right sort from my diet anyway.

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John.