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Medical Forum / Diseases and Disorders / Diabetes / May 2007weight loss
Since being diagnosed last October with diabetes I've continued to lose weight. I know this is not norm for type 2 diabetics as they are usually overweight. I'm on three 500mg of metformin a day and my bg on my meter are quite low usually between 3.5 - 5.0 before I've eaten and 7.0 - 9.5 an hour after eating.I'm 5ft 10 in height and now I weigh 12st 6lbs last October I was nearly 16 stones, as you can see this is quite a change. I have also changed my diet but nothing that drastic that would see such a change as I was quite a healthy eater before hand and I play golf twice a week for exercise. I don't have any other symptoms to speak of and feel quite fit. I was just wondering if anyone else has symptoms like myself and will my weight stop falling once my bg's are under control. My last HbA1c was 7.6 which I know is high but that included a month when I hadn't started on metformin I think my next test next month will be lower. Any help would be much appreciated and thanks for taking time to read this. >Since being diagnosed last October with diabetes I've continued to lose >weight. I know this is not norm for type 2 diabetics as they are usually [quoted text clipped - 10 lines] >metformin I think my next test next month will be lower. Any help would be >much appreciated and thanks for taking time to read this. I can only guess at the reason for your weight loss. It was never a problem for me, so I haven't read much on it, but others will be along to explain how out-of-control numbers will do that. Not a great way to lose weight. And that's your real problem. Those after-meal (post-prandial) numbers are too high, which is part of the reason your A1c is also too high. While you wait for the others to answer, here is a little light reading for you that may help: Test, test, test: http://jennifer.flyingrat.net/ Getting Started: http://loraldiabetes.blogspot.com/2006/10/d-day.html Cheers, Alan, T2, Australia. d&e, metformin 1500mg, ezetrol 10mg Everything in Moderation - Except Laughter. -- http://loraldiabetes.blogspot.com/ http://loraltravel.blogspot.com/ latest: Athens and The Adriatic > Since being diagnosed last October with diabetes I've continued to > lose weight. I know this is not norm for type 2 diabetics as they [quoted text clipped - 12 lines] > Any help would be much appreciated and thanks for taking time to > read this. I have had pretty similar experiences, only somewhat more so... I also had lots of weight loss (mostly before being diagnosed, but between about the same parameters - from 16 stone down to 12/7). And similar numbers including an HBa1c that didn't seem to reflect my usually reasonably low pre-meal numbers (implying that post-meal spikes had a tendency to last). Just today, after a year of having been diagnosed and treated as a type 2, I had a battery of other blood tests. Which should give answers to questions about liver function, c-peptide concentration (apparently reasonably good in determining your level of insulin resistance, by showing whether you actually have too *much* insulin and it's still not working properly) and at least two different immune-system antibody reactions (I believe they were something like GAD and ICA antibodies, although I may have gotten the actual acronyms wrong). Apparently they've decided I'm not really a "standard type 2" any more than a "standard type 1" (obviously can't be the latter since I do reasonably well on tablets alone) and want to find out just what the hell is really going on... (I was encouraged by the fact that they DIDN'T bother with the standard Glucose Tolerance Test that I should have had when I was first diagnosed: although I've never had one, I've done enough testing over a year to know that I can get wildly different results from the same meals and same amount of exercise on different days. Evidently they decided to believe that my test results were actually significant.) I wonder if you could be similar? Maybe you're not a "standard type 2" after all and perhaps ought to ask about the possibility of other tests such as the ones above. Jonathan.  SignaturePosted via a free Usenet account from http://www.teranews.com >Apparently they've decided I'm not really a "standard type 2" >any more than a "standard type 1" (obviously can't be the latter since >I do reasonably well on tablets alone) and want to find out just what >the hell is really going on... OK! A step in the right direction! Out of interest, where are you out of spec (apart from the weird numbers), did they say? Nicky. T2 dx 05/04 + underactive thyroid D&E, 100ug thyroxine Last A1c 5.5% BMI 25 Thanks for the info. Jonathan. I'm beginning to wonder if I'm a type 1.5 that they talk about on some of the American sites I've been on to. This is also known as slow ongoing type 1. Apparently it means I'll probably have to start to inject insulin in about 5 years time if I am this type. I don't know if this is the same as yourself or not but I believe there is a test they can do to determine if I have this type I'm just not sure what it's called or if they do it on the NHS. >> Since being diagnosed last October with diabetes I've continued to lose >> weight. I know this is not norm for type 2 diabetics as they are usually [quoted text clipped - 41 lines] > > Jonathan. > Thanks for the info. Jonathan. I'm beginning to wonder if I'm a type 1.5 > that they talk about on some of the American sites I've been on to. This is [quoted text clipped - 3 lines] > they can do to determine if I have this type I'm just not sure what it's > called or if they do it on the NHS. This is also known as LADA (Latent Auto-immune Diabetes in Adults) or slow onset type 1. Generally LADA's go from tablets to injections within 2-3 years of diagnosis. One particular test that can be done is for GAD65 antibodies, if you have these, there is a very high chance that you fit into the LADA category, especially if tablets (usually metformin) controls it initially. I fit into this type. It can sometimes be difficult when speaking with the specialists at the hospital because they tend to want to 'pigeon hole' you into a specific category, my medical notes refer to me as type 2 which is quite worrying as they have been prescribing me with medication suitable for type 2's (e.g. gliclazide). I have another appt with them in a few weeks. As my numbers have been all over the place (usually double figures after 2 hrs) it's clear the gliclazide is not working. Should have my latest A1c figures back in a week. Last was 6.0, I know it will be higher this time. Graham >> Thanks for the info. Jonathan. I'm beginning to wonder if I'm a >> type 1.5 that they talk about on some of the American sites I've [quoted text clipped - 27 lines] > Should have my latest A1c figures back in a week. Last was 6.0, I > know it will be higher this time. I had tests in the end for: - liver function (I presume they're expecting it to be over-active in terms of dumping glucose, both in amounts and timing: the doctor confirmed as much.) - C-peptide (I believe this tests for whether you're currently producing too much insulin, and/or how much you are resistant to it: the doctor seems to be expecting a somewhat above normal figure, but not within the realms of a usual Type 2: since metformin did SOME obvious good for me, but only "so far and no further".) - GAD antibodies (I believe this is the one where your immune system attacks your own pancreatic insulin-producing beta cells. I'm not sure what the results will be for this one, but certainly not within the Classic Type 1 kind of figures. Could be a case of LADA though I'm not certain of it and neither is the doctor.) - Some other antibody test, I believe the initials were ICA. (Not really a clue what this one is, but it seemed to be the one that the doctor was most expecting the unusual result on.) Not only are there more than 2 types of diabetes - even "LADA" doesn't seem to be a single homogenous variety, any more than the several types classified as "MODY" (Maturity Onset Diabetes of the Young) are. Although, "LADA" seems generally to be thought of as being more similar to type 1 but with a slower onset and happening to older people, and "MODY" being more similar to but not exactly the same as type 2s that happen to younger or thinner people than you'd normally expect to have type 2. It sounds like you could do with tests of these kinds as well. Jonathan. SignaturePosted via a free Usenet account from http://www.teranews.com > - Some other antibody test, I believe the initials were ICA. ICA-125 (islet cell antibody). In type 1.5, usually only GAD65 are found. > It sounds like you could do with tests of these kinds as well. I've had the GAD65 tests which came back positive. For some reason they are reluctant to do a C-peptide. I will take this up with the consultant, I think because it doesn't provide a great deal of information that they don't already know from the other tests. You should get all the Renal tests done (Na, K, Creat, Urea) - basically liver, kidneys etc every 3-6 months. C-peptide will show how much insulin you're producing. If the result is normal or high then it's usually a sign of type 2. If very low then type 1, if low->normal then type 1.5 or 2. Not exactly scientific. I also believe this test has to be done when the BG is about 10mmol+ so that insulin production is as high as possible. Graham Hope you get the same surprise I had. Mine was 'elevated but normal for the condition' and needed no change in the medication. And I knew it was going to be a change! REC >> Thanks for the info. Jonathan. I'm beginning to wonder if I'm a type 1.5 >> that they talk about on some of the American sites I've been on to. This [quoted text clipped - 26 lines] > > Graham |
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