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Medical Forum / Diseases and Disorders / Diabetes / October 2006

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Diabetes and depression meta study

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Peter C - 27 Oct 2006 20:44 GMT
People with Type 2 diabetes are far more likely to suffer depression than
those without, according to a study out today which was a meta analysis of
10 papers invloving  51,000 dmers. Women diabetics twice as likely as male
dmers to have depression.

http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=4129
18&in_page_id=1770

Alan S - 27 Oct 2006 22:13 GMT
>People with Type 2 diabetes are far more likely to suffer depression than
>those without, according to a study out today which was a meta analysis of
>10 papers invloving  51,000 dmers. Women diabetics twice as likely as male
>dmers to have depression.
>
>http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=4129
18&in_page_id=1770

I loved the range of comments - I'll copy them below. I
wonder if anyone has done a wider study on a possible
linkage between diagnosis with ANY chronic life-threatening
condition and depression, not just diabetes.

The comments from readers I tend to go along with Sue; Bob
sounds like such a warm, understanding and compassionate
fellow:-)

1. I was ecstatic to discover that I had a life-threatening
disease. Depressed? Of course not. I'm thrilled to know that
I can no longer eat my favourite foods; and testing my blood
several times a day at the ends of my fingers is just so
much fun! I can hardly wait till the pills no longer control
my blood sugars and I get to inject insulin every day. The
things I have to look forward to as a diabetic brings so
much happiness to my life. I can't wait to go blind, maybe
lose a limb or two and, of course, the shortened life span
that I'm expected to have.

Oh, sorry, am I supposed to be depressed?

- Sue B, Wantage, Oxon

2. Are you supposed to be happy to discover you are
diabetic. Its not like winning the lottery.

- Ryk, london

3. A brisk walk and a strong cup of tea would be my answer.

- Bob Roberts, UK

Cheers, Alan, Australia
--
http://loraltravel.blogspot.com/
latest: Liguria to Pisa
Peter C - 28 Oct 2006 01:20 GMT
> I loved the range of comments - I'll copy them below. I
> wonder if anyone has done a wider study on a possible
> linkage between diagnosis with ANY chronic life-threatening
> condition and depression, not just diabetes.

The link between diabetes and depression goes a bit deeper than being upset
because you have been dxed with a chronic illness. The medics seem to be
working towards the idea that depression results from the effects of the
metabolic changes in the brain resulting from diabetes. Which if correct
would make depression as much a recognised complication of diabetes as the
opathies. Let's hope they don't want all T2s on a precautionary valium along
with the statin and ace inhibitor and aspirin.
Perhaps the more baffling connection is why people suffering form depression
are more likely to be dxed with diabetes.
Tibbie - 28 Oct 2006 01:24 GMT
> "Alan S" <nothere@there.com> wrote in message

news:79t4k252p9cg13jn13798avdpifs8edvie@4ax.com...
> > I loved the range of comments - I'll copy them below. I
> > wonder if anyone has done a wider study on a possible
[quoted text clipped - 10 lines]
> Perhaps the more baffling connection is why people suffering form depression
> are more likely to be dxed with diabetes.

and furthermore...... are the meds that are being
blamed for causing diabetes really causing
diabetes... or is the link back to
diabetes/depression

there is a class action suit against the makers of
seroquel right now :-(

sigh
Trinkwasser - 29 Oct 2006 21:12 GMT
>> I loved the range of comments - I'll copy them below. I
>> wonder if anyone has done a wider study on a possible
[quoted text clipped - 10 lines]
>Perhaps the more baffling connection is why people suffering form depression
>are more likely to be dxed with diabetes.

While I wouldn't normally consider the Daily Mail to be any better as
a source of information than the BBC (which I quote from occasionally)
this was interesting from a personal POV since my depression and ADD
symptoms have become considerably more controllable as I got my BG
under control.

Depression is a not uncommon after-effect of a viral infection
(usually self-limiting as the virus dies out) also with some cancers
and other conditions, and just like Type 2 it's a side effect of a
surprising number and variety of drugs.

The brain and nervous system is actually a hugely complex chemical
soup, which interracts with almost all parts of the body: from that
POV it's not that surprising that chemical changes may bring about
other chemical changes. It'll be interesting to see if more specific
information emerges from this, mechanisms involved may be associated
with neuropathy also, and those get-everywhere guys the inflammatory
chemicals may have a part to play.

Oh and valium is *not* an antidepressant, in fact it may induce
depression. GABA is more involved in anxiety, serotonin norepinephrine
and dopamine are all involved in the different subsets of depressive
symptoms, plus undoubtedly other neurochemicals which cannot yet be
directly manipluated.
Jules - 27 Oct 2006 22:30 GMT
> People with Type 2 diabetes are far more likely to suffer depression than
> those without, according to a study out today which was a meta analysis of
> 10 papers invloving  51,000 dmers. Women diabetics twice as likely as male
> dmers to have depression.
>
> http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=4129
18&in_page_id=1770

<de-lurk>

It's not just T2 diabetics who are far more likely to suffer - T1
diabetics are too.  Both my husband and I (both of us T1) are being
treated and have been for several years.  Our GPs (we don't have the
same one), both say that people with any kind of "chronic" illness (the
GP's description, not ours) are more likely to have problems with
depression.

Jules
T1 since 1987
DaveT - 28 Oct 2006 01:40 GMT
> > People with Type 2 diabetes are far more likely to suffer depression than
> > those without, according to a study out today which was a meta analysis of
> > 10 papers invloving  51,000 dmers. Women diabetics twice as likely as male
> > dmers to have depression.

http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=4129
18&in_page_id=1770


> <de-lurk>
>
[quoted text clipped - 7 lines]
> Jules
> T1 since 1987

It depends what age the T1 is diagnosed. Those that are diagnosed late,
often in the same age group as T2s may be prone.
Most T1s are diagnosed young and I am afraid it is the parents of those kids
that do the worrying the children just accept it like they accept every
other new thing that happens to them. Some parts they will like others they
won't. In the end it just becomes part of life to them and they just get on
with it like the many other kids who get other diseases far worse than
diabetes.
Now if I had lived half my life normal, then out of the blue I got some
disease I new little about that made me worry about certain foods, made me
watch my exercise my weight, in fact turned my life upside down I can
understand why they are prone to depression . I do not have to worry about
food as strictly as them. I have always restricted my diet because it had to
match my insulin so it is just second nature. In fact diabetes has never
stopped me doing anything I wanted. Why because my limitations are part of
me, to change them would change me and I would not like that in the same way
as nearly every T2 has had to change and that is why they are more prone to
depression. We have it easy compared to them.
--
DaveT
T1 diagnosed 11/12/1955
BeefL & Lispro
DAFNE
Phil Aypee - 28 Oct 2006 08:21 GMT
Hi Jules,

Maybe you don't know but in medicine the term 'chronic' means 'lingering' or 'constant' (SOED).
It's a fair description of diabetes.

As regards depression - I don't really understand depression.
It certainly isn't the flip side of happy.
I'm not happy to be an insulin-resistant diabetic but I'm not depressed about it.

I'm not denying its existence, I know a couple of depressives and I have known many others.
I don't believe in the 'jolly yourself out of it' philosophy.
That's usually born of ignorance.
I think it's better for lay folk to accept that others *will* be depressed and to offer gentle support and never force any help.

Professionals can help much more.

It is far too common for people to assume that depression is simply deep unhappiness.
It isn't, it's an illness I don't understand, an illness sometimes fatal.

It doesn't surprise me that it's often associated with chronic conditions, (and diabetes is just one).
I think the illness is sometimes really a trigger for depression rather than depression just being a separate illness itself.
But depression seems to be a separate illness too so perhaps it's just coincidence that chronic conditions sometimes live alongside it.

I doubt it, though.

Signature

Take care,
Phil.

"Time wounds all heels."

Diagnosed Type 2 December 2005
Metformin - 3 × 500 mg, Gliclazide - 2 × 80 mg, Simvastatin - 1 × 40 mg
Diet and Exercise
70 kg (fairly) stable

http://uk.geocities.com/philadkinsp/diabetes.html
http://uk.geocities.com/philadkinsp/index.html

DaveT - 28 Oct 2006 11:57 GMT
> People with Type 2 diabetes are far more likely to suffer depression than
> those without, according to a study out today which was a meta analysis of
> 10 papers invloving  51,000 dmers. Women diabetics twice as likely as male
> dmers to have depression.

http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=4129
18&in_page_id=1770


Peter excuse my laymans speak but-
That does not surprise me, when you consider in a T1 case there is an attack
on the body that kills off the cells that produce insulin so we T1s are
totally dependant on what we inject no response action is touched and it
takes place in a very short period of time.
A T2s insulin effectiveness is reduced so more insulin is produced, that is
reversing some of the reactions of the normal person's response system so I
can understand if some other response systems are effected considering the
time scale that often is involved. As the disease progress's drug's (not a
replacement hormone that is natural) are introduced further messing with the
bodies natural responses.
Maybe that can also work in reverse were either the time of depression could
effect or the drugs used to control it could cause T2.
Have you noticed just how many drugs in use have diabetes as one of the
possible side effects? Not just some of those used for depression.
--
DaveT
T1 diagnosed 11/12/1955
BeefL & Lispro
DAFNE
 
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