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Medical Forum / Diseases and Disorders / Diabetes / August 2005

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chemo and diabetes.

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Loretta Eisenberg - 08 Aug 2005 01:40 GMT
I have not really given this a lot of thought, but it just came to me.

My mother had diabetes.  she had hodgkins disease and was on chemo.  She
developed the diabetes after that.

In l994, I had breast cancer.  I went through twelve rounds of chemo
therapy.  I was officially diagnosed in l999.  

At first, I thought it was genetic and did until just a few minutes ago
when this theory came into my head.

Is it possible that chemotherapy, while killing bad cancer cells, also
kills good cells, caused my pancrease not to produce insulin.

I never asked the doctor this and will at my next appointment,  Just
want to hear your opinions.
I am thinking that both my mother and I developed diabetes after having
chemo therapy.

My mother died in 1995 from complications of diabetes and cancer.  

Thanks
Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Alan S - 08 Aug 2005 02:04 GMT
>I have not really given this a lot of thought, but it just came to me.
>
[quoted text clipped - 19 lines]
>Thanks
>Loretta

I'm not sure about chemo Loretta, but many of the people on
my CLL list have prednisone as an adjunct to the chemo
treatment and that can definitely be a factor in type 2. Did
you have prednisone as part of your treatment?

Cheers Alan, T2, Australia.
Signature

Everything in Moderation - Except Laughter.

Loretta Eisenberg - 08 Aug 2005 03:12 GMT
Alan, I am happy to say that I didnt have prednisone.   It was bad
enough having cancer, but having a moon face, would have really
depressed me.  

I have been and always will be vain even though I am overweight :-)

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Grandpa Chuck - 08 Aug 2005 02:06 GMT
> I have not really given this a lot of thought, but it just came to me.
>
[quoted text clipped - 19 lines]
> Thanks
> Loretta

Loretta aren't you Type 2?
If so your pancreas is probably still working away all the time. It's
just that your body has become insulin resistant. (I think that's what
they told me.)

Signature

Grandpa Chuck
-ô¿ô-
  ~

The following information is given with the utmost respect
for the armed forces and civilians who have died in the
current war in Iraq.

According to http://icasualties.org/oif/
The number of Americans killed in Iraq as of August 6, 2005 is 1832.

Each star represents one person killed.

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1,500

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1,832

United Kingdom = 93

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Other = 101

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*

Iraqi civilian deaths are between 24,000 and 100,000 by all estimates.

Loretta Eisenberg - 08 Aug 2005 03:14 GMT
Chuck, I am type II.  Are you saying my pancreas is putting out all the
insulin that is necessary?

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
oldal4865 - 08 Aug 2005 13:31 GMT
Loretta Eisenberg wrote in message
<20752-42F6BFFD-345@storefull-3233.bay.webtv.net>...
Chuck, I am type II.  Are you saying my pancreas is putting out all the
insulin that is necessary?

Loretta

You still may be putting out more insulin than a non-diabetic.    However,
a more pertinent question is "Can you make enough insulin to cover a
non-diabetic's meal?"    (Or pass a Glucose Tolerance Test,   or produce a
FbG less than 126)

If you can't,   you are deficient in insulin and therefore "diabetic".

Non-diabetics have up to 4 times as much insulin capacity as they need to
get through the day.     If you have the T2 genes,   you are likely to get
stuck in the Type 2 Diabetes Progression which entails a progressive but
slow loss of insulin capacity.    The day your loss of insulin capacity is
enough to let your sugars go too high,   you are "diabetic".

The statistically average T2 has lost 50% of their original insulin capacity
at the time of diagnosis.      The 50% loss applied to their original 4
times overcapacity means they (statistically) have about 2 times as much
insulin capacity as a non-diabetic.   However,  since the overwhelming
majority are also highly Insulin Resistant,  that "2 times as much as a
non-diabetic"  is not enough to control their sugars.

That's why the diet and exercise therapy works so well for so many.
They're still making twice as much insulin as a non-diabetic but losing some
abdominal fat and raising their exercise level knocks their Insulin
Resistance down and they can get by.     "Get by",  not "gobble carbs" like
the non-diabetics can.

A vigorous diet and exercise program with some metformin and/or
Actos/Avandia added tends to protect the beta cells.   On the other hand,
gobble carbs,  and let everything go,  and the beta cells continue to die at
a high rate**  and you end up on insulin,  usually more than twice as much
as we T1 use.

(** "high rate":     There is a repair mechanism for T2 beta cells.   They
regenerate.   However the effect of T2 genes mean that they typically die
faster than they regenerate,  i.e. at a high rate.    That repair mechanism
is thought to be reason why some participants experienced an increase in
insulin capacity in the HOPE trial.    The Avandia knocked their Insulin
Resistance down low enough so that the repair mechanism was able to make
some headway against the death mechanism)

Regards
 Old Al
Loretta Eisenberg - 08 Aug 2005 14:38 GMT
Old Al, you are so knowledgeable,  thanks so much

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Grandpa Chuck - 08 Aug 2005 15:38 GMT
Thank you Al. You explained it much better than I could. I just knew
someone would step in and clarify it.

> Loretta Eisenberg wrote in message
> <20752-42F6BFFD-345@storefull-3233.bay.webtv.net>...
[quoted text clipped - 45 lines]
> Regards
>   Old Al

Signature

Grandpa Chuck
-ô¿ô-
  ~

The following information is given with the utmost respect
for the armed forces and civilians who have died in the
current war in Iraq.

According to http://icasualties.org/oif/
The number of Americans killed in Iraq as of August 6, 2005 is 1833.

Each star represents one person killed.

**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
500

**************************************************
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1,000

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1,500

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*********************************
1,833

United Kingdom = 93

**************************************************
******************************************

Other = 101

**************************************************
**************************************************
*

Iraqi civilian deaths are between 24,000 and 100,000 by all estimates.

Jenny - 08 Aug 2005 13:40 GMT
> Chuck, I am type II.  Are you saying my pancreas is putting out all the
> insulin that is necessary?

Loretta,

So sorry to hear that you and your mother had to deal with such a
difficult diagnosis and of your mother's death!

Without testing it is impossible to know if your type 2 diabetes was
caused by damage to beta cells or problems with cell glucose receptors.
 A fasting C-peptide test could answer that question for you.  I
assumed for years that my problem was failing beta cells, but testing
showed it was faulty receptors (or mitochondria, or something else at
the cellular level) as my pancreas is pouring out tons of insulin. My
cells just can't use it.

It could be that exposure to the powerful, toxic, drugs used chemo might
have either 1) caused the problem or 2)pushed a borderline, genetic
condition into full-fledged diabetes. Unfortunately, this is the kind of
question that probably has not been studied. I have read that chemo for
breast cancer can cause permanent cognitive problems and that it has
only been recently that this was discovered.

OTOH, there is a genetic form of type 2 diabetes common among Ashkenazi
Jews which does not result in overt obesity. In fact, a medical book
from the 1920s which I found in an antique store noted that adult
diabetes was very frequently found among Jewish people (and advised a
low carb diet as the only treatment available.)

So it is hard to know. My mom had chemo for a different kind of cancer
without developing any blood sugar problem (I get my diabetes from the
other side of the family.) OTOH, it does seem to have begun her
cognitive slide.

Signature

--Jenny

http://www.geocities.com/lottadata4u/   Diabetes info
http://www.geocities.com/jenny_the_bean/  Low Carb info

Loretta Eisenberg - 08 Aug 2005 14:39 GMT
Jenny, I am having problems with memory and I do attribute that to the
chemo.  Thanks .  I hope your mother is okay.

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Grandpa Chuck - 08 Aug 2005 15:36 GMT
> Chuck, I am type II.  Are you saying my pancreas is putting out all the
> insulin that is necessary?
[quoted text clipped - 5 lines]
> of Israel, two bastions of strength in a world filled with strife and
> terrorism.

That one I am not qualified to answer.

However, when I had my diabetes education classes they said that most
T2 diabetics still have a functioning pancreas that is releasing
insulin when it is called for, but due to insulin resistance it is not
being absorbed by the cells in a normal manner. That is the reason we
need the meds we take. Or if we are lucky we can get the control we
need through exercise and tight carb control.

I believe what some are calling T1.5 or T3 diabetics are people who
have the insulin resistance of a T2 along with a failed weakened pancreas.

Signature

Grandpa Chuck
-ô¿ô-
  ~

The following information is given with the utmost respect
for the armed forces and civilians who have died in the
current war in Iraq.

According to http://icasualties.org/oif/
The number of Americans killed in Iraq as of August 6, 2005 is 1833.

Each star represents one person killed.

**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
500

**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
1,000

**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
1,500

**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
**************************************************
*********************************
1,833

United Kingdom = 93

**************************************************
******************************************

Other = 101

**************************************************
**************************************************
*

Iraqi civilian deaths are between 24,000 and 100,000 by all estimates.

Andrew B. Chung, MD/PhD - 08 Aug 2005 07:41 GMT
> I have not really given this a lot of thought, but it just came to me.
>
[quoted text clipped - 9 lines]
> Is it possible that chemotherapy, while killing bad cancer cells, also
> kills good cells, caused my pancrease not to produce insulin.

Chemotherapy kills off dividing cells.  Your beta islet cells would not
have been dividing cells unless perhaps under the stress of metabolic
syndrome (MetS) when there may be more apoptosis.

> I never asked the doctor this and will at my next appointment,  Just
> want to hear your opinions.
> I am thinking that both my mother and I developed diabetes after having
> chemo therapy.

Type 2 diabetes is not associated with complete loss of beta islet cells
as you are proposing as a consequence of chemotherapy.

> My mother died in 1995 from complications of diabetes and cancer.

My condolences to you for your loss.

> Thanks

You are welcome, Loretta :-)

In Christ's love and service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
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jessie - 08 Aug 2005 10:16 GMT
Hello,

I have a son who was diagnosed when he was eleven with type I diabetes.
I was RH- which I was told was an auto-immune disorder and caused my
immune system to attack the fetus, I almost miscarried at 6 months, and
when my son was diagnosed I was told it developed because of an auto
immune disorder. I also read that wheat and milk can be linked, and I
have celiac and lactose intolerance. I'm just trying to find out if any
other mothers of type I diabetics have rh- blood, are celiac, or
intolerant to lactose. I know nothing about medicine.  I read about the
mother who donated part of her pancreas to her daughter, and want to
learn more about how to go about that, but can't seem to get any info
from out family doctor.

Thanks, have a great day
Jeff - 08 Aug 2005 12:06 GMT
> Hello,
>
[quoted text clipped - 6 lines]
> other mothers of type I diabetics have rh- blood, are celiac, or
> intolerant to lactose.

Yes, Yes, Yes.
,
Some mothers are Rh-. That doesn't cause diabetes. If you got something call
Rhogam while you were pregant, there should be no complications. You can
read more about Rh blood types here:
http://anthro.palomar.edu/blood/Rh_system.htm or do a web search for Rh-.

Lactose intolerance means that you don't make enough of the enzyme that
breaks down lactose to digest milk products. So when you consume milk
products, you gas, diarrhea and other problems. None of these have anything
to do with diabetes or your immune system.

Celiec disease is linked to other autoimmune diseases.
http://digestive.niddk.nih.gov/ddiseases/pubs/celiac/#9

> I know nothing about medicine.

There are many good resources on the internet.  The New York Times has a
good science section on Tuesdays. You can read Scientific American, which
has good articles on science. And you can go to your  local library and
bookstores.

>  I read about the
> mother who donated part of her pancreas to her daughter, and want to
> learn more about how to go about that, but can't seem to get any info
> from out family doctor.

If your son has diabetes, he should probably be followed by a pediatric
endocrinologist. If there is not one nearby, you should be able to find on
at major referral hospitals. Your family doctor and the pediatric
endocriniologist should be able to work together to get excellent care for
your son.

> Thanks, have a great

You too.

Jeff
Andrew B. Chung, MD/PhD - 08 Aug 2005 13:06 GMT
> Hello,
>
[quoted text clipped - 9 lines]
> learn more about how to go about that, but can't seem to get any info
> from out family doctor.

It seems you are wondering if there is a connection between your
autoimmune problems and your 11 year old son developing type 1 diabetes,
which you have correctly surmised is an autoimmune disease.  

The susceptibility toward having autoimmune diseases is inherited with
incomplete penetrance (meaning it is not always expressed even when
inherited) through alleles linked to HLA antigen so there is a
connection.

> Thanks, have a great day

You are welcome, Jessie.

In Christ's love and service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Robert - 08 Aug 2005 18:18 GMT
> > Hello,
> >
> > I have a son who was diagnosed when he was eleven with type I diabetes.
> > I was RH- which I was told was an auto-immune disorder and caused my
> > immune system to attack the fetus, I almost miscarried at 6 months, and

This is not  auto-immune but allo-immune.

> > when my son was diagnosed I was told it developed because of an auto
> > immune disorder.

This is not an auto-immune disorder. This is the mother developing
antibodies against red cell antigens RH pos on the baby.

I also read that wheat and milk can be linked, and I
> > have celiac and lactose intolerance. I'm just trying to find out if any
> > other mothers of type I diabetics have rh- blood, are celiac, or
[quoted text clipped - 6 lines]
> autoimmune problems and your 11 year old son developing type 1 diabetes,
> which you have correctly surmised is an autoimmune disease.

When it comes down to auto-immune disease that is true.
Immunology is inherited to some extent. Hemolytic disease of the newborn is
not auto-immune.

> The susceptibility toward having autoimmune diseases is inherited with
> incomplete penetrance (meaning it is not always expressed even when
[quoted text clipped - 22 lines]
> (6) http://makeashorterlink.com/?I24E5151A
> (7) http://makeashorterlink.com/?I22222129
Loretta Eisenberg - 08 Aug 2005 19:50 GMT
When I was pregnant with my daugher, they told me I was O negative and
had to take blood tests every month for the rh factor.

Only thing is that no one said to test my husband because he was also
negative and there was no problem.  I took all those blood tests for
naught. lol

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
oldal4865 - 08 Aug 2005 14:08 GMT
jessie wrote in message
<1123492561.111714.315410@g44g2000cwa.googlegroups.com>...
>Hello,
>
[quoted text clipped - 11 lines]
>
>Thanks, have a great day

  My little contribution:

My aunt had RH babies.   We were never told that it was an "auto-immune"
disorder.    She had RH- blood,   her husband had RH+ blood.   The babies
were RH+ and my aunt's body reacted to all that "foreign protein".    None
of her "blue-babies" developed diabetes.    (They didn't have any of the
good technology back then,   the baby would die soon after birth unless they
gave it massive blood transfusions)

IOW,   you had an RH problem because of your choice of a father for your
son.

Lactose intolerance is the normal,  majority condition of adult human
beings.   There is a fraction of the race,  often with a genetic heritage
from Northern Europe,  who developed the ability to retain their ability to
digest lactose after reaching adulthood.     It so happens that the US was
settled with a lot of people with Northern Europe genes so we see lactose
intolerance as something strange.

Celiac , OTOH,  is evidence of a possible genetic tendency to overreact to
allergens.    That's a rough description of T1,   the body somehow
overreacting and deciding that its own beta cells are foreign protein.

AFAIK,   we T1 keep the anti-beta cell antibody mechanism going throughout
life.   That suggests that if you gave your son some of your beta cells,
the antibodies would just go after them.    Note that the docs are a bit
uncertain on this topic though.

Not to nag,  but most of the T1 children I am personally aware of are using
some really Godawful old-fashioned insulin regimes.    Keep on looking at
the beta cell tricks** but I hope you have also looked into the efficacy of
your son's insulin regime.

I use a modern,  intensive DAFNE regime with Humalog and Ultralente and can
keep my HbA1c down below 6.   I expect to do better next year when I switch
to Humalog and Levemir.

(**the beta cell trick I am interested in:   There are folks talking about
growing human beta cells in test tubes,  then implanting them.   They think
they won't last very long in T1 or eliminate shots so non-T1 folks think
it's a waste.    However,  I know that if you give me 10-20% of my original
beta cell quota,   I could keep my PITA insulin shot routine and improve my
control to non-diabetic levels.    If I had to have simple surgery every
year or so to replace the cells,  it could easily be a cost-effective
process)

Regards
 Old Al
Jeff - 08 Aug 2005 14:14 GMT
> jessie wrote in message
> <1123492561.111714.315410@g44g2000cwa.googlegroups.com>...
[quoted text clipped - 23 lines]
> they
> gave it massive blood transfusions)

Rh babies are not an autoimmune disease. Rather, the mother's body is
reacting to a foreign protein. There is no effect on the mother. And no
autoimmune problems for the child.

> IOW,   you had an RH problem because of your choice of a father for your
> son.

Unknown. From the post, it is not possible to determine if there was an Rh
problem. A potential problem exists only if the mother doesn't get Rhogam
and has at least one previous baby who is Rh+.

This is not an autoimmune disorder.

> Lactose intolerance is the normal,  majority condition of adult human
> beings.   There is a fraction of the race,  often with a genetic heritage
[quoted text clipped - 3 lines]
> settled with a lot of people with Northern Europe genes so we see lactose
> intolerance as something strange.

There are also some people in Asia who are usually lactose tolerant. But,
most people in the world are lactose intolerant.

This is not an autoimmune problem.

> Celiac , OTOH,  is evidence of a possible genetic tendency to overreact to
> allergens.    That's a rough description of T1,   the body somehow
> overreacting and deciding that its own beta cells are foreign protein.

Celiac disease is an autoimmune disorder.

> AFAIK,   we T1 keep the anti-beta cell antibody mechanism going throughout
> life.   That suggests that if you gave your son some of your beta cells,
[quoted text clipped - 28 lines]
> Regards
>  Old Al
ted rosenberg - 08 Aug 2005 14:57 GMT
Jeff
She said she HAD an RH baby

That means
1) the father was Rh+
2) She was Rh-
3) She had a prior exposure to Rh+

SO, you HAD enough information  You seem to have a recurring problem
with genetics - This is a simple Mendelian situation.  I see where you
are incapable of understanding not non-mendalian characteristics (like
T2 diabetes).  Heaven help you if you get one of those really weird
non-mendalians like calico coloring in cats.

And, it IS an Autoimmune disease  the fetus is part of the body at
first, and the infant's blood is part of its body after birth, SO, it is
n immune reaction to part of one's own body - "AUTO"  "IMMUNE"

>>jessie wrote in message
>><1123492561.111714.315410@g44g2000cwa.googlegroups.com>...
[quoted text clipped - 90 lines]
>>Regards
>> Old Al

Signature

"...in addition to being foreign territory the past is, as history, a
hall of mirrors that reflect the needs of souls observing from the present"
Glen Cook

Jeff - 08 Aug 2005 15:16 GMT
> Jeff
> She said she HAD an RH baby
[quoted text clipped - 3 lines]
> 2) She was Rh-
> 3) She had a prior exposure to Rh+

Yet, from the medical history given, this might have been her first child
and she could have had problems for some other reason.

> SO, you HAD enough information  You seem to have a recurring problem with
> genetics - This is a simple Mendelian situation.  I see where you are
> incapable of understanding not non-mendalian characteristics (like T2
> diabetes).

Personal attack noted. It is a shame that you don't try to educate people
instead of attack them.

I disagree. While what you say is most likely true (I would be quite
surprised if it weren't), she didn't say whether this was not her first
pregancy nor did she provide adequate details to be sure this is the case.

> Heaven help you if you get one of those really weird
> non-mendalians like calico coloring in cats.
>
> And, it IS an Autoimmune disease  the fetus is part of the body at first,
> and the infant's blood is part of its body after birth, SO, it is n immune
> reaction to part of one's own body - "AUTO"  "IMMUNE"

No, it is not an autoimmune disorder. The body is attacking a foreign
protein. This usually occurs because the baby and mother's blood mix at
birth and some of the Rh+ antigen gets into the mother's bloodstream. This
usually does not occur during pregancy, but only during (or after) birth.
(http://www.texashste.com/html/path_im.htm)

Also, I would like to point out that it is the mother's body that is making
the antibodies, not the infant, even though it is the infant's blood that
the antibodies react against.

Furthermore, it is not linked to autoimmune disorders like diabetes or
lupus.

Jeff

PS. I am really sorry that you need to behave this way. You and I have a
disagreement over a particular medical topic. Big deal. That doesn't mean
you need to attack me at every chance. Just for the record, I will not
behave this way against you.

>>>jessie wrote in message
>>><1123492561.111714.315410@g44g2000cwa.googlegroups.com>...
[quoted text clipped - 95 lines]
>>>Regards
>>> Old Al
Andrew B. Chung, MD/PhD - 08 Aug 2005 16:22 GMT
> > Jeff
> > She said she HAD an RH baby
[quoted text clipped - 13 lines]
>
> Personal attack noted.

It seems to be simply an observation though understandably you find the
observation to be personal.

> It is a shame that you don't try to educate people
> instead of attack them.

What Ted enumerated would be for your education, dear Jeff:

http://makeashorterlink.com/?G1974229B

Truth is simple:

http://makeashorterlink.com/?P2264129A

The way to the truth is straight and narrow:

http://makeashorterlink.com/?A2642108A

You will remain in my prayers, dear Jeff whom I love, in Christ's holy
name.

May you reject your pride and accept Him as your personal Lord and
Savior, someday, so that you too will have eternal life and the
fascinating riches of His everlasting kingdom.

Here's how:

http://makeashorterlink.com/?I22222129

Please note that God truly made this special link describing that He is
the great "I am" and that His message is as simple as the number 2 which
is a number between 1 to 9 and reminds us of His 2 commandments,  the 2
arms of the cross, the 2nd part of the Trinity, the 2 finger sign of the
Prince of Peace [who remains *V*ictorious over death and satan], and the
2PD-OMER Approach.  Let it not ever be written that Christ did not make
His presence known here on Usenet :-)

Also, note that Exodus 16:16 continues to remind us that 16 oz plus 16
oz makes 2 pounds, which is "a certain measure of weight," which is what
"omer" literally means in Hebrew.

Enter the 2PD-OMER Approach, which can "cure" metabolic syndrome (MetS)
thereby bringing this thread back on topic for these NGs :-)

http://www.HeartMDPhD.com/wtloss.asp

http://www.HeartMDPhD.com/press.asp

You may hear me speak about the 2PD-OMER Approach in person and meet
others who have been using this WOE here:

http://www.TheHealthFair.com

You may also choose to have me speak to your group or organization about
the 2PD-OMER Approach in person for the usual and customary speaker's
fee of US$30,000.00 made as a tax-deductible contribution to
TheWellnessFoundation.com (it remains my choice to not profit personally
from the 2PD-OMER Approach):

http://www.TheWellnessFoundation.com  

In Christ's love and service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
ted rosenberg - 08 Aug 2005 17:38 GMT
>>Jeff
>>She said she HAD an RH baby
[quoted text clipped - 18 lines]
> surprised if it weren't), she didn't say whether this was not her first
> pregancy nor did she provide adequate details to be sure this is the case.

"most likely"

Yes, I can postulate a situation where it is not the case.

First, I would have to give her an injection of Rh+ blood,  Since she is
Rh-, she would become sensitized, and not have a viable reaction.  Why??
is that a likely occurance? Not in a million years.

THEN, she would need an Rh+ baby without an Rh+ father.  Possible,
mutation???

What are the odds of that happening ???

Why don't you simply postulate that she is an alien from outer space>
The odds are better.

As to your explanation of why it is technically not an autoimmune
disorder.  I'll accept you on that.  I bow to your superior knowledge of
medical jargon.

RhoGam came on the market over 40 years ago, so it is odd she didn't get
tested and inoculated at each birth, but it happens.

>  > Heaven help you if you get one of those really weird
>
[quoted text clipped - 125 lines]
>>>>Regards
>>>>Old Al

Signature

"...in addition to being foreign territory the past is, as history, a
hall of mirrors that reflect the needs of souls observing from the present"
Glen Cook

None Given - 08 Aug 2005 20:13 GMT
> RhoGam came on the market over 40 years ago, so it is odd she didn't get
> tested and inoculated at each birth, but it happens.

My niece aborted a rapist's baby, they didn't test her for anything or give
her a shot.  Later, she married and they wanted a baby, she miscarried and
was told it was because of the Rh thing, she got a shot that time.

Signature

No Husband Has Ever Been Shot While Doing The Dishes

Robert - 08 Aug 2005 20:57 GMT
> > RhoGam came on the market over 40 years ago, so it is odd she didn't get
> > tested and inoculated at each birth, but it happens.
>
> My niece aborted a rapist's baby, they didn't test her for anything or give
> her a shot.  Later, she married and they wanted a baby, she miscarried and
> was told it was because of the Rh thing, she got a shot that time.

Sorry to correct a few things about that story.
Any prenatal testing includes a type and RH along with an antibody screen to
check for Rh antibodies.
The shot is given when the mother does not have an antibody to RH. It
prevents antibodies from forming and thus prevent hemolytic disease of the
newborn in the future babies.
Once an antibody is detected and formed against Rh then the mother has to be
monitored by measuring the strength of the antibody called a titer along
with checking the amniotic fluid for abnormalities. The shot does nothing
for those mothers who already have an antibody and it is therefore not
given. It can not prevent something that is already there.
It is common practice for all threatened abortions regardless of term to do
a type and Rh. If the mother is Rh negative she is always given the shot
AFTER testing to confirm that she is Rh negative and she does not have an
antibody.
Depending on the length of pregnancy, in addition they will always check for
baby cells in the mother in all threatened miscarriage or full term
deliveries. The shot is dependent of the amount of baby cells present so
more than one shot might be required. The test quantifies the amount of baby
blood found.
When a pregnant women has an accident (trauma) then they always check for
baby cells in the mother by drawing blood regardless of the mothers or
babies Rh type. This indicates that the baby is bleeding into the mother or
out through vaginal bleeding.
These are all procedures mandated by medical practice guidelines and by
laboratory testing guidelines.
Loretta Eisenberg - 08 Aug 2005 20:59 GMT
None given, that is a tragic story.  The rh comes in on the second child
and in my mothers case it was the third child.  We are all negatives.

I am glad that your niece was able to move on with her life.

I hope they caught the bastard and threw away the key.

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
Ma¢k - 09 Aug 2005 03:02 GMT
>I hope they caught the bastard and threw away the key.
>
>Loretta

after making him a gelding.

Mâck©®
Type 1 since 1975
http://www.alt-support-diabetes.org
http://www.diabetic-talk.org
http://www.insulin-pumpers.org

"To announce that there must be no criticism of the
President, or that we are to stand by the President
right or wrong, is not only unpatriotic and servile,
but is morally treasonable to the American public."
...Theodore Roosevelt

        (o o)  
--ooO-(_)-Ooo--------------------

"I don't know half of you
half as well as I should like;
and I like less than half of you
half as well as you deserve."

Jesus never hated anyone.
Wild Monkshood - 09 Aug 2005 03:09 GMT
>>I hope they caught the bastard and threw away the key.
>>
>>Loretta
>
> after making him a gelding.

    If we're not into arts & crafts, can't we just buy 'em a gelding and
give it to 'em? :)

Wild Monkshood

> Mâck©®
> Type 1 since 1975
[quoted text clipped - 17 lines]
>
> Jesus never hated anyone.
Andrew B. Chung, MD/PhD - 08 Aug 2005 16:22 GMT
> Jeff
> She said she HAD an RH baby
[quoted text clipped - 6 lines]
> SO, you HAD enough information  You seem to have a recurring problem
> with genetics

This observation with Jeff has been made before especially when Jeff is
arguing in favor of the theory of evolution.

> - This is a simple Mendelian situation.

His problem with genetics is probably not a simple Mendelian situation.

> I see where you
> are incapable of understanding not non-mendalian characteristics (like
> T2 diabetes).  Heaven help you if you get one of those really weird
> non-mendalians like calico coloring in cats.

Heaven does not help him when he tries to convince people that the
theory of evolution should be promoted to law/postulate.

> And, it IS an Autoimmune disease  the fetus is part of the body at
> first, and the infant's blood is part of its body after birth, SO, it is
> n immune reaction to part of one's own body - "AUTO"  "IMMUNE"

Actually, in an Rh negative woman, Rh antigen is not normally part of
herself so her reaction would not be considered autoimmune.


In Christ's love and service,

Andrew

--
Andrew B. Chung, MD/PhD
Board-Certified Cardiologist

**
Suggested Reading:
(1) http://makeashorterlink.com/?G1D5217EA
(2) http://makeashorterlink.com/?W13A4250B
(3) http://makeashorterlink.com/?X1C62661A
(4) http://makeashorterlink.com/?U1E13130A
(5) http://makeashorterlink.com/?K6F72510A
(6) http://makeashorterlink.com/?I24E5151A
(7) http://makeashorterlink.com/?I22222129
Loretta Eisenberg - 08 Aug 2005 14:35 GMT
Jessie, my mother was Rh negative and I was rh negative,  My daughter
does not have diabetes.  My mother and I both had type 2.

I didnt know that they were doing pancreatic transplants,  That is
wonderful.

Loretta

--
In tribute to the United States of America and the State
of Israel, two bastions of strength in a world filled with strife and
terrorism.
 
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