Three reports of interest in the latest issue of the New
England Journal of Medicine.

The first also has implications for our separate discussion
on retinopathy and setting of diagnostic criteria.

***
Hyperglycemia and Adverse Pregnancy Outcomes
http://content.nejm.org/cgi/content/short/358/19/1991?query=TOC
Conclusions
Our results indicate strong, continuous associations of
maternal glucose levels below those diagnostic of diabetes
with increased birth weight and increased cord-blood serum
C-peptide levels.
***

Metformin versus Insulin for the Treatment of Gestational
Diabetes
http://content.nejm.org/cgi/content/short/358/19/2003?query=TOC
Conclusions
In women with gestational diabetes mellitus, metformin
(alone or with supplemental insulin) is not associated with
increased perinatal complications as compared with insulin.
The women preferred metformin to insulin treatment.
(Australian New Zealand Clinical Trials Registry number,
12605000311651.)
***

And the Editorial (full version needs payment)
http://content.nejm.org/cgi/content/short/358/19/2061?query=TOC
Gestational Diabetes — Setting Limits, Exploring Treatments

Pregnancy is associated with relative carbohydrate
intolerance and insulin resistance. Gestational diabetes
mellitus (carbohydrate intolerance first diagnosed during
pregnancy) has long been recognized as a risk factor for a
number of adverse outcomes during pregnancy, including
excessive fetal growth, an increased incidence of birth
trauma and cesarean delivery, and neonatal metabolic
abnormalities such as polycythemia, hyperbilirubinemia, and
hypoglycemia.1 This recognition has led to recommendations
to screen all pregnant women for gestational diabetes
mellitus and to treat those whose glucose-tolerance tests
exceed threshold criteria.2

The threshold criteria for diagnosing gestational diabetes
were initially specified rather arbitrarily as values
greater than 2 . . . [Full Text of this Article requires
payment]

Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraldiabetes.blogspot.com
Latest:What to Eat Until You Get Your Meter.
and Cambodia
http://loraltravel.blogspot.com/2008/03/cambodia.html