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Medical Forum / Diseases and Disorders / Diabetes / August 2007

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Eddie - 14 Aug 2007 04:20 GMT
3 months ago I stopped taking glucovance (glyburide/metformin) which I
was taking 3 times per day for a total of 3.75 mg glyb and 750 mg of
metformin.  I was running an A1C of 5.8%.  All seemed fine, but I was
concerned about taking glyburide which forces the beta cells to produce
insulin whether you need it or not.  Besides, having to make sure that
I got enough carbs to not go hypo, I was worried about the long term
affect of forcing the insulin.

My NP agreed to let me drop the glucovance and we tried (2)850 mg
tablets of Metformin. After 3 months, A1C is still 5.8%.  I'm thrilled.
I'm also learning that if I know I'm going to eat a bad meal (bad
carbs) like out in a restaurant or at a party, I can take a glucovance
before the meal and it really helps keep things in control.  I don't do
that very often, so I don't worry about long term affect of doing it
that way once in a awhile.
Ed
johnniemccoy@ - 14 Aug 2007 04:26 GMT
>3 months ago I stopped taking glucovance (glyburide/metformin) which I was
>taking 3 times per day for a total of 3.75 mg glyb and 750 mg of metformin.
[quoted text clipped - 11 lines]
> don't worry about long term affect of doing it that way once in a awhile.
> Ed

hehe.... that's what we need.... a morning after pill.

John
Eddie - 14 Aug 2007 04:36 GMT
johnniemccoy@ presented the following explanation :
>>3 months ago I stopped taking glucovance (glyburide/metformin) which I was
>> taking 3 times per day for a total of 3.75 mg glyb and 750 mg of metformin.
[quoted text clipped - 15 lines]
>
> John

Actually, more like a morning before pill.  Whatever works.  ....Ed
johnniemccoy@ - 14 Aug 2007 04:50 GMT
> johnniemccoy@ presented the following explanation :
>>>3 months ago I stopped taking glucovance (glyburide/metformin) which I
[quoted text clipped - 19 lines]
>
> Actually, more like a morning before pill.  Whatever works.  ....Ed

Really, I wonder if that could be an answer for those of us who'd like to go
out for a normal dinner once in a while.

John
Eddie - 14 Aug 2007 05:42 GMT
johnniemccoy@ was thinking very hard :
>> johnniemccoy@ presented the following explanation :
>>>>3 months ago I stopped taking glucovance (glyburide/metformin) which I was
[quoted text clipped - 24 lines]
>
> John

Could be, if you're careful.  I was at a wedding Saturday evening.  I
started with a glucovance pill.  Then had 2 rum and diet cokes, couple
of glasses of wine with dinner, coffee, some seafood wraps for
appetizers, some pasta, potato chips (homemade, couldn't resist),
meats, salads and some delicious deserts.  I felt really bloated when I
left at 8pm.  Got home and measured after about 90 minutes since
eating.  Measured 73.  I couldn't believe how low I was.  I do think
that alcohol with glyburide can make you get low, so you have to be
careful.
bj - 14 Aug 2007 18:01 GMT
> Really, I wonder if that could be an answer for those of us who'd like to
> go out for a normal dinner once in a while.

Prandin or Starlix could be useful for that.
bj
ray - 14 Aug 2007 16:01 GMT
> 3 months ago I stopped taking glucovance (glyburide/metformin) which I
> was taking 3 times per day for a total of 3.75 mg glyb and 750 mg of
[quoted text clipped - 12 lines]
> that way once in a awhile.
> Ed

My normal course of oral meds consists of metformin ER 4x500. I started
with the VA in January, and because of their archaic regimen, the doc said
the only thing she could prescribe was glyburide (also told that was not
what she would do in private practice). I have continued with the
metformin and take a glyburide once in a while when I'm running 'high' at
bedtime - it seems to have helped, overall. My last A1C was 5.2.
Ed - 14 Aug 2007 21:03 GMT
>> 3 months ago I stopped taking glucovance (glyburide/metformin) which I
>> was taking 3 times per day for a total of 3.75 mg glyb and 750 mg of
[quoted text clipped - 19 lines]
> metformin and take a glyburide once in a while when I'm running 'high' at
> bedtime - it seems to have helped, overall. My last A1C was 5.2.

Very similar regiman.  Thanks for the support.  I asked my doc if I
should try 2000 mg/day to get A1C lower.  Her answer was that 5.8 was
fine, why take more drugs.  Not sure I agree, but I'll go along with it
for now.
ed
ray - 14 Aug 2007 22:28 GMT
>>> 3 months ago I stopped taking glucovance (glyburide/metformin) which I
>>> was taking 3 times per day for a total of 3.75 mg glyb and 750 mg of
[quoted text clipped - 25 lines]
> for now.
> ed

IMHO - 5.8 is not fine. 4.8 might be fine. How are you doing with diet and
exercise? I find I need all three to keep numbers where I want them. YMMV.
Loretta Eisenberg - 14 Aug 2007 21:39 GMT
Ed, we all have to find what works for each of us individually.  You
have adopted a PLAN that is good for you and I think that is wonderful

I have learned that if I am going to have a higher carb meal, I can take
a glyset and it will be fine.  Of course, I will have the runs, but
sometimes a piece of cake is just worth it. :-)

Loretta.
johnniemccoy@ - 14 Aug 2007 22:35 GMT
> Ed, we all have to find what works for each of us individually.  You
> have adopted a PLAN that is good for you and I think that is wonderful
[quoted text clipped - 4 lines]
>
> Loretta.

...lol, Loretta. That one made me laugh.... a peice of cake is worth the
runs....lol

John
Frank t2 - 15 Aug 2007 00:37 GMT
That's OK when you know where you're running ...

"Loretta Eisenberg" <sassybklynlady@webtv.net> a écrit ...
> Ed, we all have to find what works for each of us individually.  You
> have adopted a PLAN that is good for you and I think that is wonderful
[quoted text clipped - 4 lines]
>
> Loretta.
Ed - 15 Aug 2007 04:41 GMT
> Ed, we all have to find what works for each of us individually.  You
> have adopted a PLAN that is good for you and I think that is wonderful
[quoted text clipped - 4 lines]
>
> Loretta.

I totally agree Loretta.
Frank t2 - 15 Aug 2007 12:08 GMT
If Loretta had written 'beer' instead of 'cake',
I would also agree with you and her ...

Sadly ...

"Ed" <mail@nospammers_edkirstein.com> a écrit ...
>> Ed, we all have to find what works for each of us individually.  You
>> have adopted a PLAN that is good for you and I think that is wonderful
[quoted text clipped - 6 lines]
>>
> I totally agree Loretta.
ray - 15 Aug 2007 15:54 GMT
> Ed, we all have to find what works for each of us individually.  You
> have adopted a PLAN that is good for you and I think that is wonderful
[quoted text clipped - 4 lines]
>
> Loretta.

FWIW - I tend to agree - however, I've noticed that since modifying my
diet it takes a much smaller serving to satisfy me, so often I'm still
within bounds.
W. Baker - 15 Aug 2007 17:47 GMT
:  I'm also learning that if I know I'm going to eat a bad meal (bad
: carbs) like out in a restaurant or at a party, I can take a glucovance
: before the meal and it really helps keep things in control.  I don't do
: that very often, so I don't worry about long term affect of doing it
: that way once in a awhile.
: Ed

My endo has given me Starlix, which is also a beta cell pusher, but of
much shorter duration than the glyburide.  I use this when eting out or
for holidy meals, etc.  Currently, as I am just gettign back on the
Metformin after my recent hospitalization, I will be using the Starlix a
bit more to keep my BGs in contrl while ramping back up on teh metformin
EX I use.

Wendy
 
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