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Medical Forum / Diseases and Disorders / Diabetes / August 2007

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Anyone take Collagen Supplements ?

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mancman - 12 Aug 2007 18:18 GMT
i read some research where it said that diabetics produce only 50% of the
collagen (a protein forming the skin and connective tissue) that normal
people do

and so i decided to look at supplements

because, nothing heals on me. spots/insect bites don't nor do cuts &
bruises. well eventually but often with scar tissue. it's a nightmare

anyone one know if collagen supplements help out ?

mancman
Jeff - 12 Aug 2007 18:21 GMT
> i read some research where it said that diabetics produce only 50% of the
> collagen (a protein forming the skin and connective tissue) that normal
> people do
>
> and so i decided to look at supplements

Collagen is protein. That means when you eat it, your digestive system
will break it down into amino acids. Then, your body will absorb the
amino acids and make new proteins.

So, getting enough protein will help make sure your body can make more
collagen.

However, if you have kidney disease, you may need to limit the amount of
protein you take.

So basically, except getting the right amount of protein, you can't do
much about the amount of collagen you make. I wish had better news.

Jeff

> because, nothing heals on me. spots/insect bites don't nor do cuts &
> bruises. well eventually but often with scar tissue. it's a nightmare
>
> anyone one know if collagen supplements help out ?
>
> mancman
Susan - 12 Aug 2007 18:34 GMT
> However, if you have kidney disease, you may need to limit the amount of
> protein you take.

This is dogma, not science.

In fact, a recent report of an end stage renal patient found improvement
when switched to a high protein diet.

Glucose damages kidneys, not protein.

Susan
Andrew B. Chung, MD/PhD - 12 Aug 2007 20:22 GMT
> > However, if you have kidney disease, you may need to limit the amount of
> > protein you take.
>
> This is dogma, not science.

Incorrect:

http://tinyurl.com/3ycmze

> In fact, a recent report of an end stage renal patient found improvement
> when switched to a high protein diet.

End stage renal patients typically are receiving hemodialysis where it
no longer matters because there are no longer functioning kidneys to
save with a low protein diet.

> Glucose damages kidneys, not protein.

Actually, glucose in normal physiological concentrations does not
damage kidneys.

Amino acids in excessively high concentrations because of a high
protein diet does increase glomerular filtration rate, which can
overtax kidneys that are failing for any number of other reasons (ie
diabetes, hypertension, glomerulopathies, et cetera).

Be healthy... be hungry... be blessed:

http://TheWellnessFoundation.com/PressRelease

Prayerfully in Jesus' awesome love,

Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist
Alan S - 12 Aug 2007 23:31 GMT
>x-no-archive: yes
>
[quoted text clipped - 5 lines]
>In fact, a recent report of an end stage renal patient found improvement
>when switched to a high protein diet.

Reference?

>Glucose damages kidneys, not protein.
>
>Susan


Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraltraveloz.blogspot.com/
latest: Mossman Gorge in the Daintree Rainforest
http://loraldiabetes.blogspot.com/
latest: Self-Testing and Type 2 Management
Jim Chinnis - 12 Aug 2007 19:55 GMT
"mancman" <someone@micro1.com> wrote in part:

>i read some research where it said that diabetics produce only 50% of the
>collagen (a protein forming the skin and connective tissue) that normal
[quoted text clipped - 4 lines]
>because, nothing heals on me. spots/insect bites don't nor do cuts &
>bruises. well eventually but often with scar tissue. it's a nightmare

Collagen is what scars are made of.

If you scar excessively, particularly if the scar is raised or extends
beyond the original injury, you may be producing too much collagen.

I imagine you are having problems with wounds healing because of circulation
problems. If you are having excessive scarring, you should report it to your
doctor.

>anyone one know if collagen supplements help out ?

They would help only in the odd case that you were consuming too little
protein and were unable to produce collagen as a result--not a very likely
scenario.
--
Jim Chinnis   Warrenton, Virginia, USA
Chris Malcolm - 13 Aug 2007 20:40 GMT
> "mancman" <someone@micro1.com> wrote in part:

>>i read some research where it said that diabetics produce only 50% of the
>>collagen (a protein forming the skin and connective tissue) that normal
[quoted text clipped - 4 lines]
>>because, nothing heals on me. spots/insect bites don't nor do cuts &
>>bruises. well eventually but often with scar tissue. it's a nightmare

> Collagen is what scars are made of.

> If you scar excessively, particularly if the scar is raised or extends
> beyond the original injury, you may be producing too much collagen.

Scar tissue is produced when regrowth happens in conditions of low
oxygenation, i.e., poor blood supply. The poor healing in diabetics is
usually found in the extremeties, i.e. those places most affected by
diabetic vascular complications to have the poorest blood supply. You
might be able to increase the blood supply during healing by keeping
the wound warm. You should be able to reduce its need for oxygen by
topical application of vit E, possibly supplemented by internal vit E,
because that reduces the consumption of the locally available oxygen
by the oxidants.

I did find decades ago, long before developing diabetes, that topical
application of vit E to wounds was very effective in the prevention of
the formation of scar tissue. However, you have to be careful not to
all the E to mix with sticky would dressing adhesives which it can
dissolve and carry through the skin, because that can cause very
unpleasant inflammation.

Signature

Chris Malcolm        cam@infirmatics.ed.ac.uk              DoD #205
IPAB,  Informatics,  JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK
[http://www.dai.ed.ac.uk/homes/cam/]

Alan S - 13 Aug 2007 23:40 GMT
>> "mancman" <someone@micro1.com> wrote in part:
>
[quoted text clipped - 28 lines]
>dissolve and carry through the skin, because that can cause very
>unpleasant inflammation.

That's a good point. I recently sliced the tip off my thumb
with a very sharp knife while chopping veges. The wound was
an exposed 5mm (1/4") circle of flesh which, as it slowly
healed, started looking like a crater because the flesh
wasn't moving to cover it, just forming a rim around it. It
looked like it would become a permanent and ugly scar and
was healing slowly and very tender.  After a few days I
replaced the antiseptic cream I had been using with an OTC
vitamin E cream (Redwin, with Evening Primrose Oil) and the
change was very rapid. The healing process seemed to speed
up, the tenderness quickly reduced and the skin started
covering the wound. Two months later there is no scar and
the incident is just a memory.

I wasn't aware of the problem with dressing adhesive - but
I'm usually careful to avoid the cream and adhesive merging
anyway.


Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraltraveloz.blogspot.com/
latest: Mossman Gorge in the Daintree Rainforest
http://loraldiabetes.blogspot.com/
latest: Self-Testing and Type 2 Management
Chris Malcolm - 14 Aug 2007 12:24 GMT
>>> "mancman" <someone@micro1.com> wrote in part:
>>
[quoted text clipped - 28 lines]
>>dissolve and carry through the skin, because that can cause very
>>unpleasant inflammation.

> That's a good point. I recently sliced the tip off my thumb
> with a very sharp knife while chopping veges. The wound was
[quoted text clipped - 9 lines]
> covering the wound. Two months later there is no scar and
> the incident is just a memory.

Antiseptic cream may help if there is a septic problem. But they work
by killing off bacteria by means of oxygen-consuming free radicals,
and thus they depelte local oxygen in the tissues and *retard* healing
and *promote* scar formation if there is no septic problem.

The precautionary medical use of things like antibiotics and
antiseptics causes a lot of harm. These things aren't benign!

> I wasn't aware of the problem with dressing adhesive - but
> I'm usually careful to avoid the cream and adhesive merging
> anyway.

The dressing adhesive problem is what has given the topical
application of vit E to wounds a bad name due to ignorant doctors
misinterpreting the results of badly controlled research.

(I think I'm suffering from fool intolerance today :-)

Signature

Chris Malcolm        cam@infirmatics.ed.ac.uk              DoD #205
IPAB,  Informatics,  JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK
[http://www.dai.ed.ac.uk/homes/cam/]

Alan S - 14 Aug 2007 13:10 GMT
>(I think I'm suffering from fool intolerance today :-)

That can be quite a debilitating malady for users of
usenet...

Cheers, Alan, T2, Australia.
Loretta Eisenberg - 12 Aug 2007 20:27 GMT
mancman, I have had collagen injections years back for some lines, but I
never heard of colagen supplements.  do they make skin smoother cause if
so, I* will add them to my list. lol

Loretta
Andrew B. Chung, MD/PhD - 12 Aug 2007 20:39 GMT
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ted rosenberg - 12 Aug 2007 20:58 GMT
> i read some research where it said that diabetics produce only 50% of the
> collagen (a protein forming the skin and connective tissue) that normal
[quoted text clipped - 10 lines]
>
>  
Lets start out with "supplements"

This SEEMS to be a description, but is, in fact, a legal term meaning
that it is not a food or a medicine

This ,eams that it is not covered under the Pure Food and Drug Act, anf
therefore does not require accurate labeling for content or effecacy.

SO, I can bottle sugar and lable it "collogen supplement" and sell it -
LEGALLY

In the US, you should assume that anything labled supplement may be
fraudulent
Nicky - 12 Aug 2007 21:27 GMT
>because, nothing heals on me. spots/insect bites don't nor do cuts &
>bruises. well eventually but often with scar tissue. it's a nightmare

What kind of bgs are you running?

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6%  BMI 25
Loretta Eisenberg - 12 Aug 2007 22:57 GMT
Ted, I agree with you  I dont like to take any meds that are not fda
approved.  Of course, the vitamins I take I guess are not fda approved,
but they work for me.

folic acid
B6
B12
calcium
magnesium
acidolpholis

Loretta
Jeff - 12 Aug 2007 23:38 GMT
> Ted, I agree with you  I dont like to take any meds that are not fda
> approved.  Of course, the vitamins I take I guess are not fda approved,
[quoted text clipped - 8 lines]
>
> Loretta

I hate to be a pain (but too bad).

How do you know that the vitamins you take do anything for you?

And what country are they most likely made in (hint: if you don't know,
look up toys and lead paint on the internet - the country that comes up
where they make the toys is also the country where most vitamins are made).

Now, are you sure you need them?

Jeff
Loretta Eisenberg - 13 Aug 2007 00:39 GMT
I do not take unprescribed medication.  I know that all my blood work
shows that I am in great health for a sick woman. Jeff.  They were given
to me by my endo and for some reason they help my diabetes.

I will not buy anything that is not made in the USA after the stories on
the lead in the paint from China.  I am not an uninformed person.

My car is american made too.

Loretta
ted rosenberg - 13 Aug 2007 02:49 GMT
> I do not take unprescribed medication.  I know that all my blood work
> shows that I am in great health for a sick woman. Jeff.  They were given
[quoted text clipped - 8 lines]
>
>  
You are sadly misled
There is NO requirement to show country of origin on ANY drugs or
supplements, and most drugs are NOT made in the US

As to China, they have a very simple solution.  Whie Chind does not
export many drugs, they want to.

The head of their FDA wasn't diligent enough, and some bad drugs sjowed
up on the market
They tried and executed him promptly.  They said that the NEW head of
China's FDA will be SURE that their drugs are pure, or he will rapidly
join his predecessor.
Cheri - 13 Aug 2007 03:21 GMT
>> My car is american made too.
>>
>> Loretta

Are you sure of that? It might be a Chevy or a Ford or any of the
"American" cars, but where was it made? Canada? Mexico? So many of
them are these days that buying American doesn't really mean you are,
and check out where all the assembly parts are coming from when
they're actually assembled here. :-)

Cheri
Frank t2 - 13 Aug 2007 07:53 GMT
Agreed.
TVs, radios and computers are also all made in the far east.
I used to work in the department that tried rebadging of
computers from us to Bull.

And the "all american" car you think you bought has probably
less US content than the Toyota you deprived yourself of.

"Cheri" <gserviceatinreachdotcom> a écrit ...

>>> My car is american made too.
>>>
[quoted text clipped - 7 lines]
>
> Cheri
Cheri - 13 Aug 2007 15:08 GMT
Frank t2 wrote in message
<46bffff1$0$21435$79c14f64@nan-newsreader-06.noos.net>...
>Agreed.
>TVs, radios and computers are also all made in the far east.
[quoted text clipped - 3 lines]
>And the "all american" car you think you bought has probably
>less US content than the Toyota you deprived yourself of.

I always bought what I thought were American made cars, butI found out
after the sale that the last Chevrolet I bought was made in Canada.
This time I bought a Toyota that was made in America. LOL

Cheri
Loretta Eisenberg - 13 Aug 2007 22:50 GMT
I am sure that my car is American made Cheri without a doubt.  

I have to believe someone is telling the truth.  

I dont want to have any negative thoughts about my car.  lol  It is a
1999 Caddy and it was made in the good old USA

Loretta
Kurt - 13 Aug 2007 23:10 GMT
On Aug 13, 2:50?pm, sassybklynl...@webtv.net (Loretta Eisenberg)
wrote:
> I am sure that my car is American made Cheri without a doubt.  
>
[quoted text clipped - 4 lines]
>
> Loretta

There's a way to tell what country your car was made in by looking at
the VIN number.  There is a character or number in it that will tell
you that.

http://www.articlegold.com/Article/Auto-VIN-Decoder/5874

Kurt
gg - 15 Aug 2007 09:49 GMT
You can also decode you VIN number automatically at web VIN decoder:
http://www.autobaza.pl/ab/en/web/productaa0100

Best regards,
Marcin
Frank t2 - 13 Aug 2007 23:54 GMT
Loretta,
The only thing under debate is the source of the components of cars.
Is you model a Deville? ... Seville ? ...Catera? ...Concours?

What %age of the parts in your car are made in S.America ? . China ?
... India ?
I personally have no idea, but I am willing to guess at over 40%.
Where does the steel come from ? .. USA or India (India produces a
LOT of the steel used in cars)

"Loretta Eisenberg" <sassybklynlady@webtv.net> a écrit ...
>I am sure that my car is American made Cheri without a doubt.
>
[quoted text clipped - 4 lines]
>
> Loretta
ted rosenberg - 13 Aug 2007 02:44 GMT
> Ted, I agree with you  I dont like to take any meds that are not fda
> approved.  Of course, the vitamins I take I guess are not fda approved,
[quoted text clipped - 10 lines]
>
>  
It is not what thy CLAIM too be, it is who makes them and sells them.  
With the exception of General Nutrition, the odds are that if you get a
house brand for WalMart, Rite Aide, Giant, or Walgreens, you will get
what is claimed, and look for
USP
which means that it claims to be pharmaceutical grade
mancman - 13 Aug 2007 00:08 GMT
hba1c latest 7.2%

mouse

>>because, nothing heals on me. spots/insect bites don't nor do cuts &
>>bruises. well eventually but often with scar tissue. it's a nightmare
[quoted text clipped - 5 lines]
> D&E, 100ug thyroxine
> Last A1c 5.6%  BMI 25
Nicky - 13 Aug 2007 08:24 GMT
>hba1c latest 7.2%

Right. Well, that's why things are taking an age to heal. You need to
get that lower. You a T1 or a T2?

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6%  BMI 25
mancman - 13 Aug 2007 09:05 GMT
t1. my endo sez that a fine figure. we're targeted on 7% here in the uk

mouse

>>hba1c latest 7.2%
>
[quoted text clipped - 5 lines]
> D&E, 100ug thyroxine
> Last A1c 5.6%  BMI 25
Alan S - 13 Aug 2007 10:56 GMT
>t1. my endo sez that a fine figure. we're targeted on 7% here in the uk
>
>mouse

Nicky was right. Doesn't really matter what the endo said or
what that target is. They aren't the ones with the wounds
that don't heal.

You said:

"i decided to look at supplements because, nothing heals on
me. spots/insect bites don't nor do cuts & bruises. well
eventually but often with scar tissue. it's a nightmare"

So, think about that. Why do you think they don't heal?

There has been a lot written about it, start here:
http://tinyurl.com/2nsygw

I'd suggest you reset your goals. It's not just A1c - that's
only a broad indication of past blood glucose numbers. For
example, what was your reading an hour after breakfast
today? Read this to see why I ask:
http://www.alt-support-diabetes.org/NewlyDiagnosed.htm

Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraltraveloz.blogspot.com/
latest: Mossman Gorge in the Daintree Rainforest
http://loraldiabetes.blogspot.com/
latest: Self-Testing and Type 2 Management
mancman - 13 Aug 2007 18:17 GMT
thx man, appreciated. mm

>>t1. my endo sez that a fine figure. we're targeted on 7% here in the uk
>>
[quoted text clipped - 29 lines]
> http://loraldiabetes.blogspot.com/
> latest: Self-Testing and Type 2 Management
Nicky - 13 Aug 2007 20:34 GMT
>t1. my endo sez that a fine figure. we're targeted on 7% here in the uk

Actually, Diabetes UK says never let your bg deviate from 4-7; your 7%
A1c means that you're running 8+ ALL THE TIME. Your endo is still
banging rocks together; suggest you get Bernstein's book from the
library and read up on what's possible.

This is why you're not healing:
http://www.phlaunt.com/diabetes/14045621.php

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6%  BMI 25
Chris Malcolm - 14 Aug 2007 12:39 GMT
>>t1. my endo sez that a fine figure. we're targeted on 7% here in the uk

> Actually, Diabetes UK says never let your bg deviate from 4-7; your 7%
> A1c means that you're running 8+ ALL THE TIME.

<cough> ... given certain assumptions about red blood cell lifespans,
how "all the time" is sampled, etc. ... </cough>

Generally speaking regarding A1C as a translation of some kind of BG
averaging is a rather gross oversimplification which often sort of
works under some specific data sampling and diabetic and physiological
conditions. What's more useful is the idea that a rising A1C means
your BG control is getting worse, and a falling A1C means it's getting
better.

You're right however that an A1C of 7% is only good in the sense that
it's better than 8 or 9%.

> Your endo is still
> banging rocks together; suggest you get Bernstein's book from the
> library and read up on what's possible.

> This is why you're not healing:
> http://www.phlaunt.com/diabetes/14045621.php

Exactly. Peripheral vascular damage.

Signature

Chris Malcolm        cam@infirmatics.ed.ac.uk              DoD #205
IPAB,  Informatics,  JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK
[http://www.dai.ed.ac.uk/homes/cam/]

Nicky - 14 Aug 2007 13:27 GMT
><cough> ... given certain assumptions about red blood cell lifespans,
>how "all the time" is sampled, etc. ... </cough>

Gesundheit! I haven't yet recovered about your revelation abt Scottish
male limbs on view this week :D

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6%  BMI 25
 
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