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Medical Forum / Diseases and Disorders / Diabetes / August 2007

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Test Results

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J J Levin - 09 Aug 2007 22:49 GMT
Ahh, some good news. Test results:

A1c was 5.8% (3 months ago), now 5.3%

Weight loss since February is 43 lbs  (including 7 weeks on Glucovance when
I lost NOT AN OUNCE !!!)

Metformin cut from 1,000 x 2 a day to 500 x 2 a day.

Altace 2.5 mgs. added for protein expelled by kidneys.

HDL good.

LDL up a bit, but not enough for cholesterol meds (yet). We will try
changing diet first (Mozzarella instead of Munster ???)

Thanks to everyone for your encouragement and help,

Jay
Susan - 09 Aug 2007 22:58 GMT
> Ahh, some good news. Test results:
>
[quoted text clipped - 6 lines]
>
> Altace 2.5 mgs. added for protein expelled by kidneys.

Great results, Jay!

> HDL good.
>
> LDL up a bit, but not enough for cholesterol meds (yet). We will try
> changing diet first (Mozzarella instead of Munster ???)

Jay, LDL doesn't correlate nearly as closely to heart attack risk as HDL
and triglycerides do.  Do you have the actual numbers so we can see your
ratios?

I'd eat whatever cheese I want.

Susan
J J Levin - 09 Aug 2007 23:21 GMT
> x-no-archive: yes
>
[quoted text clipped - 19 lines]
> and triglycerides do.  Do you have the actual numbers so we can see your
> ratios?

Total chol  181

HDL 36

LDL  122 (was in good range 3 months ago!

Trigs  116

Jay

> I'd eat whatever cheese I want.
>
> Susan
Susan - 09 Aug 2007 23:36 GMT
> Total chol  181
>
[quoted text clipped - 3 lines]
>
> Trigs  116

Ratios:

TGL/HDL ratio 3.22

This could stand to improve.  You want it below 3, preferably closer to
one.  The way to do that, and to raise your HDL is to cut out more
starches and sugar.

Your LDL number is fine, that's not high, but your VLDL may be more than
desirable, that's the small damaging particles.  The higher your HDL and
lower your TGL, the larger and fluffier your LDL likely is.

Your TC/HDL ratio is over 5; you want to get that lower than 4 for
reduced CVD risk.

My LDL is considerably higher than yours, but my HDL is double yours and
my TGLs are half yours, so my ratios put me in a much lower risk category.

It's not just the numbers, it's the ratios.

You're still in the early control stages and improving numbers, Jay, I'd
just advise you to eat more leafy stuff and cut out starches and sugars,
and exercise to get that HDL up and those TGLs down.

Nice work so far!

Susan
J J Levin - 09 Aug 2007 23:39 GMT
> x-no-archive: yes
>
[quoted text clipped - 33 lines]
>
> Susan

Thanks. I eat very little sugar and starches -- that's how I lost the
weight. But I could still probably improve the numbers with some more
exercise, maybe a small glass of wine a day, and more leafy stuff (gotta
watch the green stuff, though, I am on Coumadin too).

Thanks for your help,

Jay
Susan - 10 Aug 2007 00:15 GMT
> Thanks. I eat very little sugar and starches -- that's how I lost the
> weight. But I could still probably improve the numbers with some more
> exercise, maybe a small glass of wine a day, and more leafy stuff (gotta
> watch the green stuff, though, I am on Coumadin too).

Jay, if you're already eating low carb, then see how much more your
lipids improve as your weight loss continues and your IR continues to
improve.

If you have the wine, make it red and dry.

Susan
Jim Chinnis - 10 Aug 2007 01:43 GMT
"J J Levin" <jjlevin@optonline.net> wrote in part:

>Thanks. I eat very little sugar and starches -- that's how I lost the
>weight. But I could still probably improve the numbers with some more
>exercise, maybe a small glass of wine a day, and more leafy stuff (gotta
>watch the green stuff, though, I am on Coumadin too).

Jay, my understanding is that you can eat all the leafy greens you want on
Coumadin as long as you eat a fairly constant amount each day. If you
suddenly increase your consumption you need to have your prothrombin time
measured to see if the Coumadin dose needs adjusting.

You might want to ask your doctor. It's hard to cut carbs to get TGL down
and HDL up while avoiding leafy greens!

Great weight loss and A1c, BTW.
--
Jim Chinnis   Warrenton, Virginia, USA
J J Levin - 10 Aug 2007 02:12 GMT
> "J J Levin" <jjlevin@optonline.net> wrote in part:
>
[quoted text clipped - 7 lines]
> suddenly increase your consumption you need to have your prothrombin time
> measured to see if the Coumadin dose needs adjusting.

Yup. That's the plan.

Thanks!

Jay

> You might want to ask your doctor. It's hard to cut carbs to get TGL down
> and HDL up while avoiding leafy greens!
>
> Great weight loss and A1c, BTW.
> --
> Jim Chinnis   Warrenton, Virginia, USA
Will, T2 - 09 Aug 2007 22:58 GMT
> A1c was 5.8% (3 months ago), now 5.3%
>
[quoted text clipped - 3 lines]
>
> Metformin cut from 1,000 x 2 a day to 500 x 2 a day.

Fabulous results, Jay. Keep it up....  Yeah!!!

Will, T2
J J Levin - 09 Aug 2007 23:22 GMT
>> A1c was 5.8% (3 months ago), now 5.3%
>>
[quoted text clipped - 7 lines]
>
> Will, T2

Thank you, thank you (humble bow)...

Jay
ray - 09 Aug 2007 23:39 GMT
> Ahh, some good news. Test results:
>
> A1c was 5.8% (3 months ago), now 5.3%

That's great! What have you been doing?

> Weight loss since February is 43 lbs  (including 7 weeks on Glucovance when
> I lost NOT AN OUNCE !!!)

Right on!!

> Metformin cut from 1,000 x 2 a day to 500 x 2 a day.

I'd be inclined not to cut it while A1C is still above 5, but I'm no doc.

> Altace 2.5 mgs. added for protein expelled by kidneys.
>
[quoted text clipped - 6 lines]
>
> Jay
J J Levin - 09 Aug 2007 23:45 GMT
>> Ahh, some good news. Test results:
>>
[quoted text clipped - 11 lines]
>
> I'd be inclined not to cut it while A1C is still above 5, but I'm no doc.

My endo agreed to the cut because I complained of digestive issues, sleep
issues, joint pain issues, leg and feet pains, and a few other minor things
which began when I started on Metformin. Besides, my bgs are generally
excellent ( fbg usually 93-101, 2 hours later ALWAYS under 140 and very few
spikes in between -- well, there was that one incident with pizza :-).

My a1cs went from 8.4 to 8.8 to 6.9 to 5.8 to 5.3  so he's generally happy.

He did stress that I better check the bgs though. If the numbers start going
up, he wants a phone call right away and we will go back to 1,000.

Jay

>> Altace 2.5 mgs. added for protein expelled by kidneys.
>>
[quoted text clipped - 6 lines]
>>
>> Jay
Susan - 10 Aug 2007 00:17 GMT
> He did stress that I better check the bgs though. If the numbers start going
> up, he wants a phone call right away and we will go back to 1,000.

Jay, that makes no sense; you were having a very bad adverse side effect
profile from metformin.  I had a lot of those symptoms and more, and my
lipids got worse, not better, on metformin.  My bg is better now,
without it.

You have made such superb progress, I don't see why you shouldn't be
able to prove to him that you can manage on diet and exercise alone.

Also, if metformin did that to you, your DM may not be from IR, it may
be from elevated adrenal hormones, as it is in at least 10% of type 2 DM.

Susan
J J Levin - 10 Aug 2007 02:15 GMT
> x-no-archive: yes
>
[quoted text clipped - 8 lines]
> You have made such superb progress, I don't see why you shouldn't be able
> to prove to him that you can manage on diet and exercise alone.

I don't think they bgs will go up. That's why I asked for it to be reduced.
I want to do exactly as you suggest -- exercise, diet, and not go back to
1000 Metformin. The doc just wanted to make sure that I call him IF the
numbers go up.

Thanks,

Jay

> Also, if metformin did that to you, your DM may not be from IR, it may be
> from elevated adrenal hormones, as it is in at least 10% of type 2 DM.
>
> Susan
J J Levin - 10 Aug 2007 15:53 GMT
> x-no-archive: yes
>
[quoted text clipped - 5 lines]
> lipids got worse, not better, on metformin.  My bg is better now, without
> it.

Interesting ... my endo said he was not aware that my symptoms were usually
associated with Metformin.

My symptoms include constipation, fatigue,  waking in the middle of the
night and not being able to fall back asleep, and pains in my
thigh/knee/calf/foot (not all at the same time -- the pain sort of travels,
hitting different areas on different nights) ) of the leg on the side I am
sleeping on. This happens only when I lie down., If I'm lying on my left
side, the left foot will be affected. On my right side, the right foot.

Also, pains in my hands. That's very recent ( a week or so). But all the
symptoms have begun within the last 2-3 months, since I am on Metformin.

I hope the symptoms will abate now that we've reduced Metformin from 1000 to
500 mgs.

What kind of symptoms did you have?

Jay

> You have made such superb progress, I don't see why you shouldn't be able
> to prove to him that you can manage on diet and exercise alone.
[quoted text clipped - 3 lines]
>
> Susan
Susan - 10 Aug 2007 16:23 GMT
> Interesting ... my endo said he was not aware that my symptoms were usually
> associated with Metformin.

That's not good news.  :-/

> My symptoms include constipation, fatigue,  waking in the middle of the
> night and not being able to fall back asleep, and pains in my
> thigh/knee/calf/foot (not all at the same time -- the pain sort of travels,
> hitting different areas on different nights) ) of the leg on the side I am
> sleeping on. This happens only when I lie down., If I'm lying on my left
> side, the left foot will be affected. On my right side, the right foot.

> Also, pains in my hands. That's very recent ( a week or so). But all the
> symptoms have begun within the last 2-3 months, since I am on Metformin.
[quoted text clipped - 3 lines]
>
> What kind of symptoms did you have?

All of yours, alternating with diarrhea.  Severe foot and leg spasms.
And it did little for my bg; that was all due to diet.  No increase in
A1c after discontinuing it.

Susan
ray - 10 Aug 2007 19:50 GMT
>> x-no-archive: yes
>>
[quoted text clipped - 25 lines]
>
> Jay

FWIW - many patients find that side effects diminish or disappear after
some period of time. I was lucky, from the outset I had no ill effects.

>> You have made such superb progress, I don't see why you shouldn't be able
>> to prove to him that you can manage on diet and exercise alone.
[quoted text clipped - 3 lines]
>>
>> Susan
Susan - 10 Aug 2007 20:01 GMT
> FWIW - many patients find that side effects diminish or disappear after
> some period of time. I was lucky, from the outset I had no ill effects.

Mine got worse and worse.  And they were so insidious and gradual that
my doc and I didn't connect them to the metformin.  I did (he didn't)
when my liver enzymes were occasionally elevated, too.

Susan
Nicky - 10 Aug 2007 21:22 GMT
>My symptoms include constipation, fatigue,  waking in the middle of the
>night and not being able to fall back asleep, and pains in my
>thigh/knee/calf/foot (not all at the same time -- the pain sort of travels,
>hitting different areas on different nights) ) of the leg on the side I am
>sleeping on. This happens only when I lie down., If I'm lying on my left
>side, the left foot will be affected. On my right side, the right foot.

I hadn't made the connection between sleeping side - but yup. And they
all went away when I stopped the met. I feel much brighter without it,
and the unexplained pains have gone away. Still got plenty of pains
associated with other stuff, but I like not having mystery pains : )

Nice A1c, btw :D

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.6%  BMI 25
Cheri - 10 Aug 2007 00:37 GMT
J J Levin wrote in message
>Ahh, some good news. Test results:
>
>A1c was 5.8% (3 months ago), now 5.3%

Great results Jay!!!

Cheri
Alan S - 10 Aug 2007 00:39 GMT
>Ahh, some good news. Test results:
>
[quoted text clipped - 15 lines]
>
>Jay

CONGRATULATIONS!!!


Cheers, Alan, T2, Australia.
d&e, metformin 1500mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraltraveloz.blogspot.com/
latest: Mossman Gorge in the Daintree Rainforest
http://loraldiabetes.blogspot.com/
latest: Self-Testing and Type 2 Management
Loretta Eisenberg - 10 Aug 2007 00:50 GMT
Jay you sure are doing good.  congratulations.  

I am getting mine tomorrow and crossing my fingers.

Loretta
J J Levin - 10 Aug 2007 02:15 GMT
> Jay you sure are doing good.  congratulations.
>
> I am getting mine tomorrow and crossing my fingers.
>
> Loretta

Well, we want GOOD news from you!!

My fingers are crossed for you too!

Jay
 
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