> In May, 2004, I took an antibiotic called Tequin for pneumonia. At the end
> of June, 2004, I was diagnosed with diabetes. No one in either my mother's
> family or my father's family has ever had diabetes. In May, 2007, Tequin was
> taken off the market by the FDA because it had a 17times higher risk of
> causing diabetes. It does make you wonder.
>> In May, 2004, I took an antibiotic called Tequin for pneumonia. At the end
>> of June, 2004, I was diagnosed with diabetes. No one in either my mother's
>> family or my father's family has ever had diabetes. In May, 2007, Tequin was
>> taken off the market by the FDA because it had a 17times higher risk of
>> causing diabetes. It does make you wonder.
> Prednisone use (steroid) was the cause of my diabetes.
I think in my case too. The killer was ulcerative colitis, which had
me on pretty massive doses for quite a while. As a result I had a
permanently raging hunger and ate about tons more than I usually
did. The nurses in the hospital thought it very amusing that I
followed the food trolley with them round the wards in order to pick
up the extra meals from people who'd died so recently that their meals
hadn't been stopped.
> I am still on it
> 11 months later. Can not reduce dosage without return of Polymyalgia
> rheumatica.
That's a very nasty one. You have to take it for some years until the
PMR finally gets fed up and goes away. Your PMR hasn't gone, all
you're doing just now is controlling the inflammation to stop it
getting worse. It's only finally really gone when you can stop doing that.
I got PMR after the UC, I suspect partly because my native steroid
production had been damaged by the earlier heavy steroid use. And age
of course. Every doctor I saw diagnosed me as suffering from age as
well as everything else :-)
> Results of usage are dramatic: thinning skin, hair loss or
> growth, watering eyes, weight gain, almost the same symptoms as ioabetes
[quoted text clipped - 3 lines]
> reduce Prednisone dosage, but still, must be very careful of spikes --
> had one today that was a bit fierce.
It's good to have got down to 7mgs. That's around the point where it
gets really hard to get lower, especially if you suffer from age as
well :-) I was told I'd probably never be able to get off, have to
take it for the rest of my life.
The way of reducing dosage which I found worked was the alternate day
method. Keep one day's dosage the same, and reduce the other. So for
example you'd go from 7 & 7 to 7 & 6 to 7 & 5 and so on, until finally
you get down to 7 & 0. Although it has a short half life, the anti
inflammatory effects last a lot longer than the drug in the
bloodstream, and the inflammation takes a while to get started. So you
still control the inflammation, while the days of zero give your dozy
adrenal a regular kick up the backside to start doing their thing
instead of relying on your pills. As their production increases, so
your dosage is able to be reduced.
I probably had diabetes while I was doing that, or at least
progressively worsening prediabetes. Fortunately I didn't know it, so
I had one less thing to worry about :-)
Good luck with the PMR. It does eventually get fed and go away.

Signature
Chris Malcolm cam@infirmatics.ed.ac.uk DoD #205
IPAB, Informatics, JCMB, King's Buildings, Edinburgh, EH9 3JZ, UK
[http://www.dai.ed.ac.uk/homes/cam/]
Andrew B. Chung, MD/PhD - 04 Aug 2007 13:07 GMT
> >> In May, 2004, I took an antibiotic called Tequin for pneumonia. At the end
> >> of June, 2004, I was diagnosed with diabetes. No one in either my mother's
[quoted text clipped - 6 lines]
> I think in my case too. The killer was ulcerative colitis, which had
> me on pretty massive doses for quite a while.
Sad to read about your having been afflicted with UC.
> As a result I had a permanently raging hunger
Sad to read about your having issues with the hunger that arose
because the prednisone was helping you overcome your UC.
Your would not have fared as well if the prednisone had not made you
hungrier.
> and ate about tons more than I usually did.
This is the actual cause of your acquiring the visceral adipose tissue
(VAT) that caused the insulin resistance (IR/MetS) that has led to
your developing type-2 diabetes.
> The nurses in the hospital thought it very amusing that I
> followed the food trolley with them round the wards in order to pick
> up the extra meals from people who'd died so recently that their meals
> hadn't been stopped.
If you had known then as you know now that hunger is wonderful and not
being hungry is terribly bad and had taken this to heart, you would
not have overeaten and you would not have been afflicted with type-2
diabetes despite the taking prednisone for UC.
> > I am still on it
> > 11 months later. Can not reduce dosage without return of Polymyalgia
[quoted text clipped - 7 lines]
> I got PMR after the UC, I suspect partly because my native steroid
> production had been damaged by the earlier heavy steroid use.
It was more likely due to the VAT that you acquired from overeating to
kill the hunger because of your issues with the hunger.
Be hungry... be healthy... be blessed:
http://HeartMDPhD.com/PressRelease
Prayerfully in Jesus' awesome love,
Andrew <><
--
Andrew B. Chung, MD/PhD
Cardiologist