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Medical Forum / Diseases and Disorders / Diabetes / April 2007

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Just a diabetes care question :-)

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Diana - 10 Apr 2007 16:49 GMT
Is there a difference between Symlin and Byetta?

I was on the Symlin but it did not do anything to help me so the nurse took
me off it but if Byetta is different I will bring this up to her even if I
have to go in sooner than expected.

TIA !
sharppointy1 - 10 Apr 2007 18:12 GMT
> Is there a difference between Symlin and Byetta?
>
[quoted text clipped - 3 lines]
>
> TIA !

Yes, they are different.  Similar class of drug, but indicated for
different types of diabetes.  Try Googling it, I don't know the
difference well enough to explain it :-)
Diana - 11 Apr 2007 19:22 GMT
>> Is there a difference between Symlin and Byetta?
>>
[quoted text clipped - 9 lines]
> different types of diabetes.  Try Googling it, I don't know the
> difference well enough to explain it :-)

thanks for trying :-) I have searched for a difference but could not find
one that I understood.
W. Baker - 11 Apr 2007 20:13 GMT
: >> Is there a difference between Symlin and Byetta?
: >>
[quoted text clipped - 9 lines]
: > different types of diabetes.  Try Googling it, I don't know the
: > difference well enough to explain it :-)

: thanks for trying :-) I have searched for a difference but could not find
: one that I understood.
Byetta works fo rpeole who are not taking insulin , while Symlin is for
those who are taking insulin.  I gather the effects are similar, but the
drugs are not interchangeable.

Wendy
Richard Evans - 11 Apr 2007 21:08 GMT
>Byetta works fo rpeole who are not taking insulin , while Symlin is for
>those who are taking insulin.  I gather the effects are similar, but the
>drugs are not interchangeable.

I'm a T2 who has used both in conjunction with insulin.
Diana - 11 Apr 2007 21:33 GMT
>>Byetta works fo rpeole who are not taking insulin , while Symlin is for
>>those who are taking insulin.  I gather the effects are similar, but the
>>drugs are not interchangeable.
>
> I'm a T2 who has used both in conjunction with insulin.

Did either of them help if so which one? I am type 2 also. Thanks
Richard Evans - 11 Apr 2007 21:46 GMT
>>>Byetta works fo rpeole who are not taking insulin , while Symlin is for
>>>those who are taking insulin.  I gather the effects are similar, but the
[quoted text clipped - 3 lines]
>
>Did either of them help if so which one? I am type 2 also. Thanks

I found Symlin worked better. Mostly I was turned off by the
cumbersome nature of the Byetta. It comes in a pen with a 30-day
supply and had to be kept refrigerated. The Symlin came in indvidual
vials, each one with several days supply. I could carry one vial and
leave the others in the fridge. With the Byetta, I was tied to the
fridge. I *could* carry it with me on occasion, but it was too big to
fit in the pouch in which I carry my supplies.

Also, the Byetta used pen tips that had to be changed with each
injection. A pain to deal with if I was dining out. The Symlin uses
standard syringes that I can reuse several times.

Bottom line: Symlin dropped my A1C from 6.7 to 5.4.
Diana - 11 Apr 2007 21:23 GMT
> : >> Is there a difference between Symlin and Byetta?
> : >>
[quoted text clipped - 20 lines]
>
> Wendy

Oh ok now I understand. thanks :-)  I take insulin and I also take Metformin
so didn't know for sure. Thanks for helping me understand. Jim did a
wonderful job with the link it is just I don't comprehend very well. Smart
in other areas but not in understanding what I read LOL Thanks again Wendy.
Nicky - 11 Apr 2007 21:46 GMT
>Oh ok now I understand. thanks :-)  I take insulin and I also take Metformin
>so didn't know for sure. Thanks for helping me understand. Jim did a
>wonderful job with the link it is just I don't comprehend very well. Smart
>in other areas but not in understanding what I read LOL Thanks again Wendy.

Diana, Byetta works by mimicking a gut hormone that your body makes
naturally - called GLP-1. It helps your body to produce the right
amount of insulin faster, and also slows the digestion so you feel
full longer - because you are! Whether it's useful to you as a help to
diabetic control depends on how shot your beta cells are - but it
might be a help on the diet front independently of that, although it's
not supposed to be prescribed as a weight loss drug. Some people can
feel very sick from it, but most people seem to get over that. They
start you on one dose, and work you up to the second, higher dose if
required. In mice, Byetta looks like it actually regenerates beta
cells - but of course no-one knows if it does the same in humans!

There's a complementary drug called Januvia that suppresses the
hormones that remove your own GLP-1 drug - I think that's also
possible to take alongside insulin. Frank Jefferson's on it, I think -
might be worth googling his experiences?

I'm afraid I have no idea what Symlin does!

HTH,

Nicky.
T2 dx 05/04 + underactive thyroid
D&E, 100ug thyroxine
Last A1c 5.5%  BMI 25
Diana - 12 Apr 2007 00:43 GMT
>>Oh ok now I understand. thanks :-)  I take insulin and I also take
>>Metformin
[quoted text clipped - 28 lines]
> D&E, 100ug thyroxine
> Last A1c 5.5%  BMI 25

Thank you Nicky and yes you were a great help in my understanding.
rk - 12 Apr 2007 05:24 GMT
>>Oh ok now I understand. thanks :-)  I take insulin and I also take
>>Metformin
[quoted text clipped - 29 lines]
> D&E, 100ug thyroxine
> Last A1c 5.5%  BMI 25

Well from what you state Byetta does, it doesn't do the same as
Symlin.  Symlin is another Hormone our bodies produce when it
produces Insulin.  The hormone is Amylin.  Almost all Type 1's
also have a loss of the Amylin hormone.
J.C. Hartmann - 11 Apr 2007 03:49 GMT
> Is there a difference between Symlin and Byetta?
>
[quoted text clipped - 3 lines]
>
> TIA !

http://tinyurl.com/2rdb8n
Diana - 11 Apr 2007 19:45 GMT
>> Is there a difference between Symlin and Byetta?
>>
[quoted text clipped - 4 lines]
>> TIA !
> http://tinyurl.com/2rdb8n

Thank you Jim. I appreciate the link. I read the information but I don't
understand most of it. I did see your last paragraph and understood it and I
am wondering why this nurse practitioner did not try the Byetta first since
I am type 2.

I will ask her when I see her again because something does have to give
here. I have no life this way. I aim to claim it back again though so will
try whatever works.

Again thank you and I hope your post then helps many many others.
 
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