<<snip>>
For researchers, these results may stimulate efforts to develop safer
alternatives to warfarin and better treatments for people with brain
hemorrhages
<<snip>>

The above states .. "we have been causing ten times the rate of brain
hemorrhage and this FACT will now enable us to test more drugs BECAUSE
we NOW .. have .. MANY more patients / trusting souls to work with ..
"

Source: American Academy of Neurology (AAN)

Drug Linked to Increase in Brain Hemorrhage Cases
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Medical News   Keywords
WARFARIN, BRAIN HEMMORHAGE, NEUROLOGY, AMERICAN ACADEMY OF NEUROLOGY,
STROKE
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Description

The rate of brain hemorrhages associated with blood thinning drugs
quintupled during the 1990s, according to a study published in the
January 9, 2007, issue of Neurology, the scientific journal of the
American Academy of Neurology. In people over age 80, the rate
increased more than tenfold.

Newswise - The rate of brain hemorrhages associated with blood
thinning drugs quintupled during the 1990s, according to a study
published in the January 9, 2007, issue of Neurology, the scientific
journal of the American Academy of Neurology. In people over age 80,
the rate increased more than tenfold.

Most of the increase is due to greater use of the drug warfarin, which
is commonly prescribed to prevent blood clotting. Blood clots can lead
to ischemic stroke, the most common type of stroke. An intracerebral
brain hemorrhage is a stroke caused by bleeding in the brain.

The use of warfarin increased after studies showed it reduced the risk
of stroke caused by blood clots for people with atrial fibrillation, a
condition that causes irregular heart rhythm and becomes more common
as people age.

"Warfarin is highly effective in preventing ischemic stroke among
people with atrial fibrillation," said study author Matthew L.
Flaherty, MD, of the University of Cincinnati. "For many people, the
benefits of preventing ischemic stroke continue to outweigh the risk
of a hemorrhagic stroke.

"Our findings should not discourage the use of warfarin when it's
appropriate. Doctors can use these findings to make sure they are
weighing the risks and benefits of warfarin use for their patients.
For researchers, these results may stimulate efforts to develop safer
alternatives to warfarin and better treatments for people with brain
hemorrhages."

For the study, researchers identified all patients in the greater
Cincinnati area hospitalized with a first-time intracerebral
hemorrhage during three years: 1988, 1993-94, and 1999. In 1988, the
annual rate of intracerebral hemorrhages associated with use of blood
thinning drugs was .8 cases per 100,000 people. In 1999, the rate was
4.4 cases per 100,000 people. For people age 80 and older, the rate
increased from 2.5 in 1988 to 45.9 in 1999.

The study was supported in part by the National Institute of
Neurological Disorders and Stroke.

The American Academy of Neurology, an association of more than 20,000
neurologists and neuroscience professionals, is dedicated to improving
patient care through education and research. A neurologist is a doctor
with specialized training in diagnosing, treating and managing
disorders of the brain and nervous system such as stroke, Alzheimer's
disease, epilepsy, Parkinson disease, and multiple sclerosis. For more
information about the American Academy of Neurology, visit http://
www.aan.com.

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