Yesterday I had a hypo from Byetta; I hadn't thought it was possible. It
was after breakfast, I tested 79 on my fasting test before breakfast. I
injected the Byetta and ate some leftover ravioli, it was 70 carbs. I know
the carbs were close because I had ravioli for dinner the night before and
weighed my portion. 2 hours after eating, I tested 80 and at about 4 hours,
I started having vision problems, a sure sign of hypo in me. I tested 61 so
had a glucose tab and 2 small cookies. It took a long time for the carbs to
start working because the Byetta was still keeping my stomach from
emptying. I tested again at the 6 hour and was 124, I was 102 at 8 hours.
Byetta frequently delays my BG peaks for 4-6 hours but I never went that
low at 4 hours. It has me worried because it is hard to treat a hypo when
the Byetta is keeping your stomach closed.
Anon
coonskin@amestwp.com - 07 Dec 2006 17:21 GMT
"Yesterday I had a hypo from Byetta; I hadn't thought it was possible.
It was after breakfast, I tested 79 on my fasting test before breakfast.
I injected the Byetta and ate some leftover ravioli, it was 70 carbs. I
know the carbs were close because I had ravioli for dinner the night
before and weighed my portion. 2 hours after eating, I tested 80 and at
about 4 hours, I started having vision problems, a sure sign of hypo in
me. I tested 61 so had a glucose tab and 2 small cookies. It took a long
time for the carbs to start working because the Byetta was still keeping
my stomach from emptying. I tested again at the 6 hour and was 124, I
was 102 at 8 hours.
Byetta frequently delays my BG peaks for 4-6 hours but I never went that
low at 4 hours. It has me worried because it is hard to treat a hypo
when the Byetta is keeping your stomach closed."
In the two byetta groups I follow in a small minority this happens. This
does not include those who take drugs which produce insulin by the brute
force method along with it.
In most the byetta causes insulin release around the 90 bg mark and
stops when falling below it.
Stomach emptying is only one of the effects, it slows not stops it
happening.
I suspect with you and those mentioned above very high carb meals
prevents somehow the byetta effect of turning off liver glucose release
which along with the carb spike adds even more glucose in a downward
spiral.
As you mention, adding carbs only tends to aggravate it which is
consistent with that view. More carbs more insulin release along with
more liver glucose and a hypo results.
I would suspect the carb slug from the night before also for distorting
the liver turn off effect byetta has. Many incretin effects are
affected by the previous meal.
Byetta is not delaying the glucose peak, with a large carb intake the
byetta is starting to decrease in your blood at 4 hours with plenty of
carbs incoming still, you can not cheat mother nature.