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Medical Forum / Diseases and Disorders / Diabetes / December 2006

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New Diabetes Drug Improves Blood Sugar, Weight Loss (HealthDay via Yahoo! News)

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admin@ng2000.com - 06 Dec 2006 00:56 GMT
http://www.ng2000.com/fw.php?tp=diabetes

TUESDAY, Dec. 5 (HealthDay News) -- The new drug called rimonabant
(brand name Acomplia) helped improve blood sugar control and promote
weight loss in people with type 2 diabetes, according to study results
released Tuesday by drug maker Sanofi-Aventis.
GysdeJongh - 06 Dec 2006 20:53 GMT
> http://www.ng2000.com/fw.php?tp=diabetes
>
> TUESDAY, Dec. 5 (HealthDay News) -- The new drug called rimonabant
> (brand name Acomplia) helped improve blood sugar control and promote
> weight loss in people with type 2 diabetes, according to study results
> released Tuesday by drug maker Sanofi-Aventis.

In plain English :
Throughout your body there are "Buttons"
These "Buttons" are pressed without you knowing it ; ouside your "will
power"
It causes some people to eat too much
Now finally there is a medicine , a pil , not an injection , that will glue
this "Button" firmly in place
Now YOU can decide yourself what to eat and what not to eat
You will loose weight
You will improve in a lot of ways

Disclaimer :
I do not sell it
The good news is from a pharmaceutical company ; they will get very rich
very soon
I will start it as soon as I can
I think
T2 , 1000 mg Metformin / day
Exercise
Low Carb

Here is the source :
Rimonabant is the first in class that works on the canaboid I receptors
Sanofi-aventis 12/05/06
http://en.sanofi-aventis.com/index.asp
http://en.sanofi-aventis.com/Images/20061205_Serenade_en_tcm24-14785.pdf

In the SERENADE study, treatment-naive type 2 diabetes patients receiving
rimonabant 20mg per day for a duration of six months significantly lowered
their HbA1c levels by 0.8% from a baseline value of 7.9 as compared to a
reduction of 0.3% in the placebo group (p=0.002). In addition, patients with
an HbA1c level greater than or equal to 8.5% at baseline, significantly
reduced their HbA1c by 1.9% with rimonabant as compared to 0.7% with placebo
(p<0.0009). Over 50% of patients in the rimonabant arm of the trial achieved
HbA1c levels below 7%, the target for good glucose control as recommended by
the American Diabetes Association (ADA).(i) Importantly, these improvements
in blood glucose control were accompanied by significant and clinically
meaningful reductions in body weight of 6.7 kg (14.8 lbs) in patients
treated with rimonabant 20mg, while those patients on placebo lost only 2.7
kg (5.95 lbs) (p<0.0001).

hth
Gys
 
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