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Medical Forum / Diseases and Disorders / Diabetes / December 2006Max Metformin Dosage
What's the maximum dosage per day of Metformin which doctors prescribe? Does it differ between Metformin Regular & Metformin XR? > What's the maximum dosage per day of Metformin > which doctors prescribe? Depends on the formulation. > Does it differ between Metformin Regular & Metformin > XR? Yes. 2000 mg is max for the extended release (XR aka ER) 2550 mg is max for the regular These maximum numbers are for healthy kidneys and close monitoring of serum creatinine. May GOD continue to heal our hearts with HIS living water so that we can love others a little bit more, dear neighbor whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love > What's the maximum dosage per day of Metformin > which doctors prescribe? > > Does it differ between Metformin Regular & Metformin > XR? This is the generally accepted rule: Metformin HCI The usual starting dose is one 500-milligram tablet twice a day, taken with morning and evening meals. Your doctor may increase your daily dose by 500 milligrams at weekly intervals, based on your response up to a total of 2,000 milligrams. An alternative starting dose is one 850-milligram tablet a day, taken with the morning meal. Your doctor may increase this by 850 milligrams at 14-day intervals, to a maximum of 2,550 milligrams a day. The usual maintenance dose ranges from 1,500 to 2,550 milligrams daily. If you take more than 2,000 milligrams a day, your doctor may recommend that metformin be divided into three doses, taken with each meal. Metformin XR The usual starting dose is one 500-milligram tablet once daily with the evening meal. Your doctor may increase your dose by 500 milligrams at weekly intervals, up to a maximum dosage of 2,000 milligrams a day. If a single 2,000-milligram dose fails to control your blood sugar, you may be asked to take 1,000-milligram doses twice a day. If you need more than 2,000 milligrams a day, the doctor will switch you to regular metformin. C >> What's the maximum dosage per day of Metformin >> which doctors prescribe? [quoted text clipped - 30 lines] > milligrams a day, the doctor will switch you to regular > metformin. Why different max dosage between Regular & XR? > Why different max dosage between Regular & XR? Pharmacokinetics. May GOD continue to heal our hearts with HIS living water so that we can love others a little bit more, dear neighbor whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love > What's the maximum dosage per day of Metformin > which doctors prescribe? 2500 mg. > Does it differ between Metformin Regular & Metformin > XR? Don't think so.  SignatureSee my webpage: http://mysite.verizon.net/juliebove/index.htm > > What's the maximum dosage per day of Metformin > > which doctors prescribe? [quoted text clipped - 5 lines] > > Don't think so. Actually it does. 2500 mg is excessive for the XR (aka ER) May GOD continue to heal our hearts with HIS living water so that we can love others a little more, dear Julie whom I love unconditionally. Prayerfully in Christ's amazing love, Andrew <>< -- Andrew B. Chung Cardiologist, Atlanta, Georgia, USA http://HeartMDPhD.com/HolySpirit As for knowing who are the very elect, these you will know by the unconditional love they have for everyone including their enemies (Matthew 5:44-45, 1 Corinthians 13:3, James 2:14-17). http://HeartMDPhD.com/Love >>What's the maximum dosage per day of Metformin >>which doctors prescribe? > > 2500 mg. It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S. Australia, I believe, has a max of 3000. >>Does it differ between Metformin Regular & Metformin >>XR? > > Don't think so. The maximum daily dose of XR is 2000, by the manufacturer's recommendation. Susan > x-no-archive: yes > [quoted text clipped - 13 lines] > The maximum daily dose of XR is 2000, by the manufacturer's > recommendation. So why would the max daily dose differ between XR & Regular? > So why would the max daily dose differ between XR & Regular? I dunno, perhaps because it isn't processed/excreted as quickly, a littler dab'll do ya. :-) Susan >It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S. >Australia, I believe, has a max of 3000. News to me - not that I dispute it, just wasn't aware of that. Cheers, Alan, T2, Australia. d&e, metformin 1000mg, ezetrol 10mg Everything in Moderation - Except Laughter. -- http://loraldiabetes.blogspot.com/ http://loraltravel.blogspot.com/ latest: Pompeii, Amalfi, Bari >>It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S. >>Australia, I believe, has a max of 3000. > > News to me - not that I dispute it, just wasn't aware of > that. I think Jan dug that up some time ago when we were discussing it. Susan > x-no-archive: yes > [quoted text clipped - 5 lines] > > I think Jan dug that up some time ago when we were discussing it. And I can't remember where from either :) >> x-no-archive: yes >> >>>>It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S. >>>>Australia, I believe, has a max of 3000. >>> >>> News to me - not that I dispute it, just wasn't aware of >>> that. >> >> I think Jan dug that up some time ago when we were discussing it. > And I can't remember where from either :) Possibly from here: http://www.npsradar.org.au/site.php?page=1&content=/npsradar/content/latestnews.html >>> x-no-archive: yes >>> [quoted text clipped - 13 lines] > >http://www.npsradar.org.au/site.php?page=1&content=/npsradar/content/latestnews.html Thank you. Another new and useful site I hadn't seen before. Cheers, Alan, T2, Australia. d&e, metformin 1000mg, ezetrol 10mg Everything in Moderation - Except Laughter. -- http://loraldiabetes.blogspot.com/ http://loraltravel.blogspot.com/ latest: Pompeii, Amalfi, Bari On 12/2/06 3:14 PM, in article 12n4287no9eor21@news.supernews.com, "Ozgirl" <are_we_there_yet@maccas.com> wrote: >>> x-no-archive: yes >>> [quoted text clipped - 14 lines] > http://www.npsradar.org.au/site.php?page=1&content=/npsradar/content/latestnew > s.html I wonder if there has been a change in their thinking on the maximum dose. I know that when I was first put on it my doctor and the Diabetes Teaching Centre said that 2500mg. was the max. Martha T2 Canada > x-no-archive: yes > > It's actually just a tad higher, at 3 x 850 mg: 2550 in the U.S. > Australia, I believe, has a max of 3000. > > Susan Thats the same as it is here in the UK. Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid control more than anything else at that dose.!! The drug company responsible ( which one??) really need to start addressing the pharmacologic aspects of this drug. IMHO it is primarily to deal with obesity/T2 ! Very few reports suggest the contary. Larry Cloudedbrains wrote: > > x-no-archive: yes > > [quoted text clipped - 4 lines] > > Thats the same as it is here in the UK. : Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid : control more than anything else at that dose.!! The drug company : responsible ( which one??) really need to start addressing the : pharmacologic aspects of this drug. IMHO it is primarily to deal with : obesity/T2 ! Very few reports suggest the contary. : Larry I don't believe tha tMetformin is used primarily as a product fo rdealing with obesity. It may result in an average weight loss of about 8 lbs! Not a great deal if one is obese. It deals with the release of glucagon from the liver, giving you less glucose running around in the bloodstream, as well as helping with insulin resistance, not pirimarily fo rweight loss at all. It doesn't tend to cause you to gain weight as inculin or actos and avandia can. Wendy Metformin is used in people likely to have a level of insulin resistance! Its one of the primary drugs used in t2's IK as its proven to work extremely well! I only take 1000mg a day as dont tolerate more even on the slow release! > : Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid > : control more than anything else at that dose.!! The drug company [quoted text clipped - 13 lines] > > Wendy > Metformin is used in people likely to have a level of insulin resistance! > Its one of the primary drugs used in t2's IK as its proven to work extremely > well! Uh, did you think Wendy was saying something contradicting that? Priscilla > I only take 1000mg a day as dont tolerate more even on the slow release! > [quoted text clipped - 15 lines] > > > > Wendy > Cloudbrains: 3 grams/day?? Well this drug is more for obesity/lipid > control more than anything else at that dose.!! The drug company > responsible ( which one??) really need to start addressing the > pharmacologic aspects of this drug. IMHO it is primarily to deal with > obesity/T2 ! Very few reports suggest the contary. Actually, it's not a weight loss or lipid lowering drug at all. It improves insulin sensitivity and, to some degree, inhibits glucose release from the liver. Susan |
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