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Medical Forum / Diseases and Disorders / Diabetes / December 2006

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How bad does NPH suck?

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Lynn - 29 Nov 2006 19:22 GMT
I've got four weeks left before my due date, and my insulin resistance has
noticeable increased.  It is a struggle to drop my carbs low enough maintain
good control - especially with all of the holiday foods.  Exercise is
possible, but even slow walking brings on uncomfortable contractions.  With
work and a lot of discipline, I do still have the capability of keeping my
numbers within range, but it is extremely frustrating.  I finally asked the
Docs about taking insulin, and all they would prescribe is NPH - 5 units in
the AM and PM to start out with.  99% of the posts I've read make NPH sound
like the drug from hell, which makes me extremely wary of even picking up
the prescription.  The only other insulin they will prescribe is Regular,
but only after they "see how I do on NPH".

So.  My questions are -
Is NPH likely to cause more harm than good?
Isn't Regular insulin available without a prescription?  Would this be a
better option inspite of the Doc's opinion?
Are there any other non-prescription insulin options?
And finally, should I just suck it up and go without any?

Lynn
GD, 36wks
Gantlet - 29 Nov 2006 19:37 GMT
you can also try to ask your question at the American Diabetes Associations
message boards. good luck wish i could help more.

http://community.diabetes.org/n/pfx/forum.aspx?nav=messages&webtag=adatype2

Signature

Tom

www.TomsDiabeticDiary.com

> I've got four weeks left before my due date, and my insulin resistance has
> noticeable increased.  It is a struggle to drop my carbs low enough
[quoted text clipped - 18 lines]
> Lynn
> GD, 36wks
Ozgirl - 29 Nov 2006 19:53 GMT
> I've got four weeks left before my due date, and my insulin resistance has
> noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 17 lines]
> Lynn
> GD, 36wks

Lynn, I believe any insulin would be better than none. Don't
cut the carbs, treat the consequences instead. The last
month or so of pregnancy puts an enormous amount of pressure
on the pancreas. Having said that the major problems caused
by high bg's in pregnancies are not a factor at this point.
The problem you may encounter if bg's are too high at this
stage is baby gaining extra weight. What exactly are your
bg's running at? I would still opt for the insulin, you
don't need the worry of trying to keep excellent control
with the big job ahead in a few weeks ;) All you need
insulin for at this stage is to assist with some bg
lowering, not tight control.
Kurt - 29 Nov 2006 20:16 GMT
> I've got four weeks left before my due date, and my insulin resistance has
> noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 14 lines]
> Are there any other non-prescription insulin options?
> And finally, should I just suck it up and go without any?

Hi Lynn,

I've never had GD but I have used NPH and I agree with your assessment
that it is the insulin from hell!  Last time I used R it was available
without presciption but you should never just arbitrarily switch
medications without conjsulting your doctor, especially with insulins
as they all have different release and duration times.  What I would
suggest to you is to express your concerns to your doctor and ask to
switch to a different kind of insulin and if he reuses then I would get
a second opinion from another doctor, preferably an endo.  Good luck.

Best,
Kurt
T1 using Humalog and Lantus
Ozgirl - 29 Nov 2006 20:28 GMT
> > I've got four weeks left before my due date, and my insulin resistance has
> > noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 25 lines]
> switch to a different kind of insulin and if he reuses then I would get
> a second opinion from another doctor, preferably an endo.  Good luck.

With 4 weeks to go there is not a lot of time for doctor
shopping. Lynn is controlling but with a lot of effort (and
no doubt stress). A bit of any insulin at this point will
take a bit of that stress away. If she were to be on insulin
full time, outside of pregnancy then there would be time for
experimentation and choices. A set amount of insulin twice a
day for a few short weeks is going to cause less stress than
chasing all over looking for a more suitable insulin at this
point in her pregnancy. I'd go with what her doctor
recommends if it were me.
TigerLily - 29 Nov 2006 20:41 GMT
good reply Jan

it's the insulin needs of pregnancy that need to
be addressed

i went thru my entire pregnancy on NPH insulin and
had FEWER problems with it when i was pregnant
than when i wasn't

5 units is a very conservative dose of NPH to
start at...... i'd say, go with your Dr's
intentions and follow thru..... you'll do just
fine

ps....... Lantus and Levemir aren't approved for
use in pregnancy right now

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> "Kurt" <kurtwheeling1965@hotmail.com> wrote in message

news:1164829816.045411.167490@80g2000cwy.googlegroups.com...

> > > I've got four weeks left before my due date, and my
> insulin resistance has
[quoted text clipped - 56 lines]
> point in her pregnancy. I'd go with what her doctor
> recommends if it were me.
Ozgirl - 29 Nov 2006 20:53 GMT
> good reply Jan
>
[quoted text clipped - 15 lines]
> > "Kurt" <kurtwheeling1965@hotmail.com> wrote in
> message

news:1164829816.045411.167490@80g2000cwy.googlegroups.com...

> > > > I've got four weeks left before my due date,
> and my
[quoted text clipped - 86 lines]
> doctor
> > recommends if it were me.

I used actrapid and protophane for my GD pregnancies. I saw
my endo at every ante natal visit and he just adjusted for
me each time from the data in my log book.
Donna B - 29 Nov 2006 20:56 GMT
In alt.support.diabetes on Wed, 29 Nov 2006 13:41:27 -0700  in Msg.#

> good reply Jan

Finally! I found out who Jan is. <G>

Signature

Donna B  : ^>  <*>
06-07-06 Diagnosis T2 hbA1C 8.1, D&E & Metformin 500mg.
09-11-06 hbA1C 5.0

"We are going through a tough period when the culture of violence has been
expanding & our world faces disaster scenarios like the clashes of
civilizations & polarizations in various directions. Therefore, we need
mutual understanding among different beliefs & civilizations more than any
time in history." - Turkey’s prime minister, Recep Tayyip Erdogan, after a
meeting with the pope. NYT, 11-28-06

Alan S - 29 Nov 2006 22:30 GMT
>In alt.support.diabetes on Wed, 29 Nov 2006 13:41:27 -0700  in Msg.#
>
>> good reply Jan
>
>Finally! I found out who Jan is. <G>

Shh! Don't tell anyone else...

Cheers, Alan, T2, Australia.
d&e, metformin 1000mg, ezetrol 10mg
Everything in Moderation - Except Laughter.
--
http://loraldiabetes.blogspot.com/
http://loraltravel.blogspot.com/
latest: Pompeii, Amalfi, Bari
Jackie Patti - 07 Dec 2006 17:09 GMT
> I've never had GD but I have used NPH and I agree with your assessment
> that it is the insulin from hell!  Last time I used R it was available
[quoted text clipped - 4 lines]
> switch to a different kind of insulin and if he reuses then I would get
> a second opinion from another doctor, preferably an endo.  Good luck.

Can you get an appointment with an endo in under a month there?

I've never gotten in to see one that fast...
rk - 07 Dec 2006 18:11 GMT
: > I've never had GD but I have used NPH and I agree with your assessment
: > that it is the insulin from hell!  Last time I used R it was available
[quoted text clipped - 8 lines]
:
: I've never gotten in to see one that fast...

I can call up my endo and get an appointment within 2 days, usually it's one
day.  I've also done this when searching for a new endo and got in within 1
week.

Signature

Reisa, T1, Animas IR1250 Pumper
DX-5/00 ASD-7/00
A1C: 6.2% (8/24/06)
Daily CHO: 150-200gm
TDD: 34-38u

Jackie Patti - 07 Dec 2006 19:04 GMT
> I can call up my endo and get an appointment within 2 days, usually it's one
> day.  I've also done this when searching for a new endo and got in within 1
> week.

I've been able to get in to see a current endo in a week or two, but
never to see a new endo in under a month.

Where are you?  Just curious.
rk - 07 Dec 2006 19:14 GMT
: > I can call up my endo and get an appointment within 2 days, usually it's one
: > day.  I've also done this when searching for a new endo and got in within 1
[quoted text clipped - 4 lines]
:
: Where are you?  Just curious.

happened the same when I lived in CA (99% of my life) and now that i'm in
OH it's still the same.  Might be the fact that I'm a T1. JIA.

Signature

Reisa, T1, Animas IR1250 Pumper
DX-5/00 ASD-7/00
A1C: 6.2% (8/24/06)
Daily CHO: 150-200gm
TDD: 34-38u

Hi_Therre - 07 Dec 2006 23:12 GMT
>: > I've never had GD but I have used NPH and I agree with your assessment
>: > that it is the insulin from hell!  Last time I used R it was available
[quoted text clipped - 12 lines]
>day.  I've also done this when searching for a new endo and got in within 1
>week.

Two days?  Damn RK, you must have the Midas touch.  It took me 3 weeks
to get an appt with a new dentist tomorrow morning.  A couple years
ago the ol GP said it would take about 2 to 3 months to see an endo in
Ft Smith.
rk - 08 Dec 2006 00:45 GMT
: >: > I've never had GD but I have used NPH and I agree with your assessment
: >: > that it is the insulin from hell!  Last time I used R it was available
[quoted text clipped - 17 lines]
: ago the ol GP said it would take about 2 to 3 months to see an endo in
: Ft Smith.

I guess..
Kurt - 08 Dec 2006 04:40 GMT
> : > I've never had GD but I have used NPH and I agree with your assessment
> : > that it is the insulin from hell!  Last time I used R it was available
[quoted text clipped - 12 lines]
> day.  I've also done this when searching for a new endo and got in within 1
> week.

Same here.  Mine on the same day if it's really important, he always
squeezes me in but I have only done that once.  A lot might depend on
what insurance you have - if you're HMO it might take longer.

It might help for someone to be more urgent in your needs when setting
up an appointment and dealing with the gatekeeper.

Kurt
oldal4865 - 29 Nov 2006 21:42 GMT
>I've got four weeks left before my due date, and my insulin resistance has
>noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 17 lines]
>Lynn
>GD, 36wks

   NPH is the insulin from Hell for people who must shoot exactly as much
as they need. . .no more,  no less.   That's me and every other T1 in the
world.    The problem is the variability of NPH.    Fast today,  slow
tomorrow,  medium next Tuesday.   That means that the large doses needed for
T1 can cause random hypos.

Folks like you do not shoot "exactly as much as they need,  no more,  no
less".    You use insulin as a supplement.   You deliberately shoot "too
little"    That means the "from Hell" aspect rarely applies.

Rule of Thumb:  "Exactly as much" as a non-pregnant T1 needs = ~ 0.2
units/day/kg body wt.   A late term pregnant T1 can easily require 2 times
as much,   Late term pregnant T2 women can easily require twice as much
again.     That means if she weighed about 110 lb,   the rule of thumb for a
late term pregnant T1 woman would call for somewhere around 20 units per
day.   It looks like your doc is starting low.

One key to avoiding the "from Hell" aspect. . .instead of trying to get by
with one or two big doses during the day,  split the total daily dose into
several doses.   I was splitting it into 4 doses when I switched to a more
modern insulin.   Someone like you,  who deliberately shoots "too little"
might get away with 2-3 doses/day.

All of these multiple doses assume you are really concerned about going low
or going hypo.

More doses = lower chance of hypo;
Fewer doses = greater chance of hypo.

In the U.S.,  NPH is not a prescription insulin.   Neither is Insulin R.
You walk into Wal-Mart,  plunk down your money,  and walk out with either
insulin.   Of course,  No prescription = No insurance reimbursement.   IIRC,
Wal-Mart Insulin R is less than $20/vial.   Don't know about NPH prices.

However,   folks in your shoes will likely end up using Insulin R about the
same way as NPH with the proviso that you inject even more often during the
day.   Nothing wrong with that.    Guy once stabilized himself during a
period of severe problems by shooting a small dose of Insulin R every few
hours,  night and day.   IIRC,  it was every 3 hours over the entire 24
hours.   A royal pain but it worked fine.   You're not T1 so you might get
by with a few less.

However,   as far as controlling FbG,   NPH is one of the better insulins so
long as you don't have to shoot too-big a dose.  Just keep the dose small
enough so that you don't go hypo at 3 a.m.,  (umm. . .you have to test at 3
a.m. for best results).

FWIW,  I had the best results controlling FbG with NPH when I shot as close
to midnight as possible.   That meant that NPH was most likely peaking after
3 a.m.,  i.e.  "after" our time of least need for insulin and "during" our
time of maximum need for insulin to control FbG.

Insulin supplementation is generally a fine idea for any T2 at any time.  It
will not do "more harm" so long as you keep the doses within reason,   that
is,  deliberately shooting "too little" and thus relying on your
still-active T2 beta cells to fine tune your sugars.

One trick with NPH,  shoot a small dose 3 hours before a meal.    That puts
the most common NPH insulin peak into the middle of the Post Prandial bG
peak.   Then shoot a small dose around midnight to put the most common peak
into the early morning hours.

The more conservative docs don't like using analog insulins on pregnant
ladies.    Insulin R and NPH are as close to "human" insulin as the pharma
companies can manage.

Regards
 Old Al
Lynn - 30 Nov 2006 00:27 GMT
Thanks everyone for the replies.  You guys are great.  I agree that
treatment from an Endo would be much better - I don't have a lot of
confidence in my OB's knowledge of diabetes - but I just don't have the time
left to pursue that option.  I know that a large baby is the only concern at
this stage of the pregnancy, but I had a nightmare of a birth with my first
child - a 9.5 pounder - so it is extremely important to me not to grow one
that big again.  ;-)

Random hypos were my biggest fear.  When the nurse said they were giving me
NPH, I had this image in my head of checking my blood every hour around the
clock to make sure I wasn't crashing.  Around 65% of my 2 hour numbers are
under 120, so I was really hoping for a fast acting insulin to use as a
correcting bolus.  Also, my fasting bGs run from 90 to 105, so going low in
the middle of the night is a big concern.  I am, however, usually awake
around 3 am for a bathroom run, so it wouldn't be a big deal to check and
see how I'm doing.  It sounds like 5 units of NPH is low for my body weight
(170) anyway, so I feel more secure.  I did pick up the 'script, but I think
I will wait until the morning to start.

Lynn
GD, 36wks
Ozgirl - 30 Nov 2006 00:42 GMT
> Thanks everyone for the replies.  You guys are great.  I agree that
> treatment from an Endo would be much better - I don't have a lot of
[quoted text clipped - 3 lines]
> child - a 9.5 pounder - so it is extremely important to me not to grow one
> that big again.  ;-)

Most people have a bit of a nightmare with the first. Head
size counts :)

> Random hypos were my biggest fear.  When the nurse said they were giving me
> NPH, I had this image in my head of checking my blood every hour around the
[quoted text clipped - 6 lines]
> (170) anyway, so I feel more secure.  I did pick up the 'script, but I think
> I will wait until the morning to start.

You could test it for day time first before doing a night
shot. But the amount isn't a lot and you aren't going to be
reducing carbs are you?
Lynn - 30 Nov 2006 01:02 GMT
> You could test it for day time first before doing a night
> shot. But the amount isn't a lot and you aren't going to be
> reducing carbs are you?

I'll wait until the morning to start just for my own peace of mind.  ;-)  I
have a strong dislike of medications in general.  I don't even take Tylenol
for a headache.  I've only gained 6 pounds during the pregnancy, though, so
I won't be reducing my carbs any more.

I do have another question, though.  The syringes they gave me are from
ReliOn - individually wrapped, 29 gauge, 0.3cc, $17 for 100 of them.  Do you
guys use this kind more than once?  Also, I've never injected insulin before
so I'm a little nervous about it (the procedure, not the pain).  Anything to
watch out for?  Wasn't I supposed to get something to clip the needle off
for disposal purposes?

Make that several questions.

Lynn
Larry from N.J. - 30 Nov 2006 01:36 GMT
Lynn, here is a site that will give you a video on insulin injections!! Hope
it helps

http://www.bddiabetes.com/us/main.aspx?cat=1&id=258

>> You could test it for day time first before doing a night
>> shot. But the amount isn't a lot and you aren't going to be
[quoted text clipped - 15 lines]
>
> Lynn
Lynn - 30 Nov 2006 01:52 GMT
> Lynn, here is a site that will give you a video on insulin injections!!
> Hope it helps
>
> http://www.bddiabetes.com/us/main.aspx?cat=1&id=258

Very nice.  Thanks Larry.
oldal4865 - 30 Nov 2006 12:05 GMT
>> Lynn, here is a site that will give you a video on insulin injections!!
>> Hope it helps
>>
>> http://www.bddiabetes.com/us/main.aspx?cat=1&id=258
>
>Very nice.  Thanks Larry.

  The BD demo outlines a super-conservative protocol.   Those of us who are
"stuck" with a lifetime of injections tend to streamline the process,
mostly with no ill effects    (Zero ill-effects for me over the last 10
years).    So don't panic if you miss one of their super-safe steps.

My shortcuts:

  1.   I re-use needles,   usually about 4 times but sometimes more.
        But if I drop an uncapped syringe,  it's history.
  2.  I inject enough air in the vial for several shots when I start a new
syringe.
       That means I only inject air with a new,  "perfectly" sterile,
"perfectly" empty syringe.
  3.  I skip the alcohol swab
  4.  I don't bother with warming my insulin.   I inject cold,  straight
from the refrigerator.
  5.  I often inject through my clothing
  6.  I use a plastic bottle gleaned from the household waste as a sharps
container.

A comment on the fat hypertrophy, fat atrophy and scarring of the fat
mentioned in the BD blurb.   Those are conditions more often seen in the
old, animal insulin days.   They are not seen as often with the new human
and analog insulins.

Regards
 Old Al
Lynn - 30 Nov 2006 13:30 GMT
>>> Lynn, here is a site that will give you a video on insulin injections!!
>>> Hope it helps
[quoted text clipped - 31 lines]
> Regards
>  Old Al

Thanks.  I gave myself my first injection this morning.  Didn't even feel
the needle go in.  I didn't bother with the alcohol.  I like the idea of
only using a new syringe to inject air into the vial.

One concern that I had was the injection site.  The skin on my belly is
stretched tight - no chance of pinching any fat there.  Besides that, I have
this fear of the insulin going into the amniotic sac or worse, the baby
kicking the wrong place at the wrong time and getting stuck.  I injected
into my hip, but I can't really pinch any skin there either.  I left the
needle in for a few seconds, but a drop of insulin came out when I removed
the needle.  Also, the needle is 1/2 inch.  Much longer than I expected.
Should I stick the whole 1/2 inch in?

Lynn
Larry from N.J. - 30 Nov 2006 13:46 GMT
Hi Lynn

I have only been injecting for 1 year now, but was instructed that the
"Less" body fat to use a shorter needle. I'm using an (8mm)  5/16 length due
to my Low body fat. I would "Think" you are using a longer than needed
needle if you can't pinch up the fat. Check with your Doc on that. This is
just my scenario I am in!

>>>> Lynn, here is a site that will give you a video on insulin injections!!
>>>> Hope it helps
[quoted text clipped - 47 lines]
>
> Lynn
Larry from N.J. - 30 Nov 2006 13:50 GMT
>>>> Lynn, here is a site that will give you a video on insulin injections!!
>>>> Hope it helps
[quoted text clipped - 47 lines]
>
> Lynn
oldal4865 - 30 Nov 2006 18:04 GMT
Lynn wrote in message ...

>Thanks.  I gave myself my first injection this morning.  Didn't even feel
>the needle go in.  I didn't bother with the alcohol.  I like the idea of
[quoted text clipped - 10 lines]
>
>Lynn

   I had that same problem when I was a skinny guy.   AFAIK,  they
recommend shoving the needle all the way in but you don't have to shove it
in at right angles to your body.    I "angled" it in until I got fatter and
changed to the shorter needles.

Back of the upper arm usually has more fat available but I can't manage the
contortions.

I use 5/16 inch long by 31 gauge needles.      I much prefer the lack of
pain and convenience of the shorter,   thinner needles.   I use BD  (no
choices allowed with my mail order plan).   I don't know if Relion come in
the shorter, thinner styles.

Sometimes I see that drop,  sometimes I don't.   The standard attack is to
leave the syringe in the fat layer for up to 10 seconds.    The drop is
particularly annoying when you use a pen.   I never did figure out how to
use a pen and not get that drop.

The drop is not much of a problem to me.   I set my own insulin doses then
report them to the doc every 6-12 months.   In effect,  I inject what I need
to to make it work.   I may "think" I am injecting 9 units,   may actually
be injecting 8 units because of the drop,  but I don't care because the
dose. . .whatever it really is. . .is working.

I shoot my slow insulins into my thighs.   I find that so painless that I
cannot shoot through clothes lest I miss,  not notice,  and just dribble the
insulin over the skin.    I use the top side of my upper thighs as viewed
when sitting.   Some folks use one of the two inner sides of their upper
things as viewed when sitting.   In contrast to my pain-free experiences
with thighs,  one of our former posters found much of his thigh to be
uncomfortably sensitive.   YMMV

You don't want to shoot NPH into a muscle!     The first (and only time)
that I tried for a self-administered NPH buttocks shot,  that's what
happened.   Into the muscle means much faster absorption which send me very
low.    Also, I have read some vague reports that direct injection of
insulin into muscle or into a vein at the concentrations* of insulin
available in vials to us common folk causes some damage .

(*When the docs use IV insulin,  they dilute vial insulin 100-fold,  then
piggy back the diluted insulin into a steadily flowing saline drip)

Gallows Humor:   Dr Biggs' IV insulin protocol has some subtle humor in it.
One of the instructions reads:

"Call endocrine MD**   if. . . .other physicians turn off drip for any
reason"

(**Dr Biggs or one of his partners)

Regards
 Old Al
Larry from N.J. - 30 Nov 2006 21:37 GMT
> Lynn wrote in message ...
>>
[quoted text clipped - 57 lines]
> insulin into muscle or into a vein at the concentrations* of insulin
> available in vials to us common folk causes some damage .

Hi Al
I agree, and I "Learned" from this group when I inject to 'PULL" back on my
syringe after injection ( A few units), look at syringe to make sure no
blood is present, then INJECT   Hope this is correct??  Larry
> (*When the docs use IV insulin,  they dilute vial insulin 100-fold,  then
> piggy back the diluted insulin into a steadily flowing saline drip)
[quoted text clipped - 10 lines]
> Regards
>  Old Al
Alexander Arnakis - 30 Nov 2006 05:52 GMT
>    NPH is the insulin from Hell for people who must shoot exactly as much
>as they need. . .no more,  no less.   That's me and every other T1 in the
>world.    The problem is the variability of NPH.    Fast today,  slow
>tomorrow,  medium next Tuesday.   That means that the large doses needed for
>T1 can cause random hypos.

I was on an NPH/Regular regimen for years, before going to my current
Lantus/Humalog treatment. I've found that it's not the insulin (of any
type) that's variable, but rather the body's constantly changing
needs. These changing needs include both the obvious (like variable
food intake and exercise), as well as the non-obvious (like
psychological stress, sub-clinical colds or flu, or random kicking in
of the body's own insulin production).

The difference is that with NPH (and to a lesser extent, Regular) you
have to tailor your food intake and exercise to fit the insulin,
whereas with Lantus/Humalog it's the other way around. This gives you
a lot more flexibility with your meals and (I've found) is a great
help in avoiding weight gain.

I still get as many hypos with Lantus/Humalog as I did with
NPH/Regular. The only way for a Type 1 to avoid hypos altogether is to
have the target BG in a high "safe" range -- but that would invite
more long-term complications.

Regarding the alleged "large doses" required by Type 1's, my total
combined daily dosage is typically less than 50 units. (And it's
remained about that much over 41 years of diabetes.) This is less than
what many Type 2's need, with their insulin resistance.
Lynn - 30 Nov 2006 11:27 GMT
> The difference is that with NPH (and to a lesser extent, Regular) you
> have to tailor your food intake and exercise to fit the insulin,
> whereas with Lantus/Humalog it's the other way around. This gives you
> a lot more flexibility with your meals and (I've found) is a great
> help in avoiding weight gain.

Now that you mention it, I remember this when my younger brother was first
dx with T1 almost 11 years ago.  They had him on a very strict diet - when
and how much to eat.  His blood sugar was under control with this method,
but he was 14 at the time, very active and athletic, and had high calorie
needs that were not being met by the diet.  It was awful seeing him hungry
all of the time, and dropping weight that he didn't need to lose.  After a
few months, Mom was able to get him in to see a juvenile diabetes specialist
who immediately changed his regimen to use insulin to match his diet instead
of the other way around.  It was a life saver for him.

Lynn
shoppa@trailing-edge.com - 29 Nov 2006 22:31 GMT
> I've got four weeks left before my due date, and my insulin resistance has
> noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 10 lines]
> So.  My questions are -
> Is NPH likely to cause more harm than good?

It's a start. It has a mild peak at approx 4-8 hours. Others here will
badmouth it but it and Regular kept me alive for several decades, so I
don't see the harm in the vile sense you're talking about.

With any insulin hypoglycemia is a risk. NPH's peak is more prolonged
and mild than regular and this makes it in a way the most benign for
hypo risks. The one gotcha is the middle of the night, but actually any
long-lasting insulin might undesirably peak there.

It's not really the type of the insulin, but how skillfully it is used.
If your docs are very comfortable with NPH, it's a fine place to start.

> Isn't Regular insulin available without a prescription?  Would this be a
> better option inspite of the Doc's opinion?

Both Regular and NPH are non-prescription in all of the US.

> Are there any other non-prescription insulin options?
> And finally, should I just suck it up and go without any?

No, don't go without any. Won't do you any good.

It is not as hip as the other long-duration insulin analogs, but it may
also be true that the long-duration insulin analogs were not yet
officially tested for use by pregnant women.

Tim.
Ma¢k - 30 Nov 2006 14:46 GMT
[Default] On Wed, 29 Nov 2006 14:22:37 -0500, "Lynn"
<noemail@noemail.com> Maniacally Screamed the following like a drunken
"Lynn" <noemail@noemail.com> into the madness of usenet:

>I've got four weeks left before my due date, and my insulin resistance has
>noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 17 lines]
>Lynn
>GD, 36wks

If you want this baby, you need to follow your doctors advice on this
one.  Diabetic Pregnancies are high risk and need high risk teams to
help manage them.  Anyone online giving you advice to do something
against your instructions would be a fool.

The approach to add insulin slowly and cautiously is the correct one.
The doctors do not want to add too much insulin too fast sending you
hypo by mistake

Take it slow and follow the diabetic pregnancy specialist's advice. If
you don't have one, contact http://www.diabeticmommy.org and find out
which types of doctors you should be seeing.

Signature

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Lynn - 30 Nov 2006 14:59 GMT
> [Default] On Wed, 29 Nov 2006 14:22:37 -0500, "Lynn"
> <noemail@noemail.com> Maniacally Screamed the following like a drunken
[quoted text clipped - 39 lines]
> you don't have one, contact http://www.diabeticmommy.org and find out
> which types of doctors you should be seeing.

Mack,

Thanks for responding.  I know that the newsgroup posters can only give
opinion, but I've always felt that the experience of many people who have
been there, done that is as valuable as one doctor's advice.  In this case,
the replies have made me feel much more secure about following orders.

I also wanted to say that I hope you and your loved ones find comfort in
mourning the loss of your mother.

Lynn
Kurt - 30 Nov 2006 17:16 GMT
> > [Default] On Wed, 29 Nov 2006 14:22:37 -0500, "Lynn"
> > <noemail@noemail.com> Maniacally Screamed the following like a drunken
[quoted text clipped - 75 lines]
> been there, done that is as valuable as one doctor's advice.  In this case,
> the replies have made me feel much more secure about following orders.

Mack is right and the only one besides myself to really tell you the
truth about your need to work with your doctor.  Insulin is not
something one should play around with because it can be a very
dangerous medication, and also one that saves our lives.  How's that
for a paradox? :)

Experience of others is always interesting to read but when it comes to
medication, especially insulin, any change must be done under the
supervision of a medical professional.  

Best,
Kurt
David - 01 Dec 2006 06:44 GMT
Hello Lynn,

> I've got four weeks left before my due date, and my insulin resistance has
> noticeable increased.  It is a struggle to drop my carbs low enough maintain
[quoted text clipped - 7 lines]
> the prescription.  The only other insulin they will prescribe is Regular,
> but only after they "see how I do on NPH".

First of all, congratulations on your upcoming birth.

I was diagnosed nearly 25 years ago and have been on various insulins
the whole time.  It is manageable but you must take extreme care and
this would be far more to ask of what is a hopefully temporary problem
in your case.  I also have a friend that just was diagnosed with GD
8 weeks before her due date.  They gave her insulin, though I don't
know what was prescribed.  She was scheduled for a C-section and
didn't make it to term due to an insulin induced low that wasn't
taken care of before she went in for a non-stress test.  They had
to get the baby out 9 days earlier than planned.  Mother and
son are doing fine.  The GD went away immediately after the birth.

> So.  My questions are -
> Is NPH likely to cause more harm than good?
> Isn't Regular insulin available without a prescription?  Would this be a
> better option inspite of the Doc's opinion?
> Are there any other non-prescription insulin options?
> And finally, should I just suck it up and go without any?

My advise is to cope as best as you can without the insulin.  If your
Bg is high or you can't cope for another month use the insulin and
dose that was prescribed.  Check your Bg's to make sure you are fine.

Do not use any faster acting insulins.  NPH doesn't have any long
term problems, nor short ones.  It is far more manageable than
Regular or any other shorter acting insulin.  The dose should be
small as you only want to help your blood sugar to stay lower
for the coming month.  You still need the willpower to help
eat right, check your sugars, and have a healthy baby.

The reason that Regular, fast acting, and too high a dose of
NPH are a hazard is that you may recover from a problem but
the baby will have a harder time.  You want a blood sugar
in the range your doctor wants and if NPH will help try it.
Just make sure to check your sugars and make sure you aren't
low or high.  Stay in touch with your doctor and if you go
low get food or get help immediately.

> Lynn
> GD, 36wks

Good luck to you and your child,

David
 
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